Porocarcinoma is a rare, cutaneous adnexal malignancy usually seen in elderly patients. We present three females with varying lesions located at the head region with a history of a sudden increase in growth. Histologically, all were composed of nests of basaloid cells showing atypia, mitotic figures and eccrine-differentiated ductal elements. One patient underwent excision (0.5 cm margin) and was recurrence-free one-month post-op. This series also brings a brief review of the current literature on porocarcinoma.
Eccrine Porocarcinoma

No abstract available.
Eccrine Porocarcinoma ; Poroma*

Eccrine porocarcinoma is a very rare, locally-aggressive, potentially fatal, malignant cutaneous neoplasm that arises from the intraepithelial ductal portion of the eccrine sweat gland. Eccrine porocarcinoma may develop either spontaneously or from a longstanding benign eccrine poroma. Herein, we describe two cases of eccrine porocarcinoma and review the related literature.
Eccrine Porocarcinoma* ; Poroma ; Sweat Glands

Eccrine porocarcinoma (EP) is a rare malignant tumor arising from the intraepidermal eccrine duct. The tumor cells frequently contain glycogen, but prominent clear cell changes in EP are rarely reported. A 78-year-old woman presented with a slightly pruritic, erythematous, verrucous plaque on her left thigh. Histopathological examination revealed intraepidermal tumor cell nests composed of small basaloid cells and duct-like structures lined by periodic acid-Schiff (PAS)-positive cuticles. Besides the typical findings of EP, clear cell changes were predominantly observed in the tumor cell aggregations. Herein we report a case of the clear cell variant of EP rarely reported in previous literature.
Aged ; Cell Aggregation ; Eccrine Porocarcinoma ; Female ; Glycogen ; Humans ; Thigh

Malignant eccrine poroma is a rare skin appendageal tumor arising from the intraepidermal ductal portion of the eccrine sweat gland. It may develop either spontaneously or from a long-standing eccrine poroma. It usually affects the aged and is located most commonly on lower extremities. We report a case of malignant eccrine poroma occurring on the suprapubic area of a 75-year-old Korean man. He underwent wide excision and flap coverage.
Aged ; Eccrine Porocarcinoma ; Humans ; Lower Extremity ; Poroma ; Skin ; Sweat Glands

Eccrine porocarcinoma is a rare malignant tumor arising from the intraepidermal ductal portion of the eccrine sweat gland. Seborrheic keratosis is a common epithelial tumor in elderly patients; it is not considered to be precancerous. We report a case of eccrine porocarcinoma associated with seborrheic keratosis in a 69-year-old male. Such a case has not been reported in Korean dermatologic literature. Although reports of seborrheic keratosis transforming into a sweat gland tumor are rare in worldwide literature, the present case suggests that seborrheic keratosis may develop into malignant sweat gland tumors.
Aged ; Eccrine Porocarcinoma* ; Humans ; Keratosis, Seborrheic* ; Male ; Sweat Glands

Aged ; Eccrine Porocarcinoma ; pathology ; Female ; Humans ; Sweat Gland Neoplasms ; pathology

Malignant eccrine poroma is a rare malignant tumor that arises from the intraepithelial ductal portion of the eccrine sweat gland. It may be developed either spontaneously or from a preexisting benign eccrine poroma. We report a case of malignant eccrine poroma on right lower abdomen in a 78-years-old female, which has been present for 1 year. In our case the tumor demonstrated without local invasion and distant metastasis, and was successfully removed by surgery.
Abdomen* ; Eccrine Porocarcinoma* ; Female ; Humans ; Neoplasm Metastasis ; Poroma ; Sweat Glands

A ‘collision’ tumor refers to the existence of two different neoplasms within the same tumor. Sometimes, the term ‘biphasic tumor’ is also used. However, a ‘collision’ tumor is defined as the occurrence of two neoplasms within proximity of each other yet maintaining distinctly defined, separate boundaries. In contrast, a ‘biphasic’ tumor demonstrates two or more phenotypically distinct neoplastic cell populations merging within the same space. Here, we report a case of collision tumor associated with sarcomatoid eccrine porocarcinoma and basal cell carcinoma arising in a 57-year-old male patient.
Carcinoma, Basal Cell* ; Eccrine Porocarcinoma* ; Humans ; Male ; Middle Aged

PURPOSE: Eccrine porocarcinoma is a very rare, potentially fatal tumor which arises from the intraepidermal portion of the eccrine sweat ductal apparatus. It does not have a characteristic clinical feature but does have a high incidence of metastasis. It may be developed de novo or in a preexisting benign eccrine poroma. It usually affects older people and is located most commonly on lower extremities. We report a rare case of eccrine porocarcinoma which developed on the back without metastasis. METHODS: The patient was a 94-year-old woman who showed a painful, ulcerated, dark brown colored polypoid 3.5x3.0cm sized mass on the back for 3 years. We totally excised the lesion including normal tissue. RESULTS: After wide excision of the lesion, pathologist reported an eccrine porocarcinoma. Histopathologic findings reveal that the classic type of eccrine gland carcinoma, eccrine porocarcinoma. Immunocytochemical studies showed a positive reactivity to anti-EMA antibody and anti-CEA antibody. CONCLUSION: Authors experienced a rare case of primary eccrine porocarcinoma on the back. Because of the propensity to develop local recurrence, wide excision of the primary tumor with histologic confirmation of negative margins represents the only curative treatment regimen for eccrine porocarcinoma.
Eccrine Glands ; Eccrine Porocarcinoma ; Female ; Humans ; Incidence ; Lower Extremity ; Neoplasm Metastasis ; Poroma ; Recurrence ; Sweat ; Ulcer