Objective:To explore the impact of continuous nursing education on the quality of life, psychological state and satisfaction of patients with inflammatory bowel disease based on micro-video.Methods:In chronological order, 83 patients with inflammatory bowel disease (hospitalized from January to June, 2019 in Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology) were divided into two groups, the control group with 42 cases (discharged from the hospital from January to March, 2019) carried out regular telephone continuing nursing education and the intervention group with 41 cases (discharged from hospital from April to June, 2019) were provided the continuous nursing education in the form of telephone plus micro-video. Before intervention and after 3 months of intervention, quality of life, levels of anxiety and depression and nursing satisfaction were evaluated by inflammatory bowel disease questionnaire (IBDQ), Self-rating Anxiety Scale(SAS), Self-rating Depression Scale(SDS), digital table method and compared between the two groups.Results:There was no significant difference in quality of life, levels of anxiety and depression before intervention between the two groups( P>0.05). After 3 months of intervention, the scores of IBDQ, SAS, SDS were 155.1±23.7, 58.7±15.1, 59.5±11.1 in the intervention group and 115.7±21.7, 71.5±16.7, 72.8±12.0 in the control group, the differences between the two groups were statistically significant ( t values were 7.910, 3.642, 5.223, P<0.01). The nursing satisfaction score was 89.32±6.34 in the intervention group and 81.45±7.21 in the control group, the difference between the two groups was statistically significant ( t value was -5.284, P<0.01). Conclusions:Continuous nursing education in the form of micro-videos can increase the quality of life of the inflammatory bowel disease patients, improve mental state and their nursing satisfaction in further.

Humans ; Pneumonia ; Pulmonary Fibrosis ; T-Lymphocytes, Regulatory ; Th17 Cells

Aim To investigate the therapeutic value of fosinopril in heart failure.Methods Thirty SD rats were divided into three groups at random.Rats in heart failure group and fosinopril group were given an 8 weeks overswimming exercise to induce heart failure and the heart failure rats in fosinogril group were treated with fosinopril orally (2 mg?kg?d-1) for 6 weeks.14 weeks later the hemodynamic indexes, myocardiac apoptosis rate, left ventricular mass index (LVMI) and myocardiac interstitial fibrosis were determined.Results The hemodynamic indexes in heart group were remarkably different from those in normal control group, while there was a significant improvement in fosinopril group (P

0.05),but in ages(P

Aortic Valve ; Fibroma ; Heart Neoplasms ; Humans

Aged ; Benzylisoquinolines ; therapeutic use ; Bronchoalveolar Lavage ; Female ; Humans ; Male ; Middle Aged ; Oxidative Stress ; Phytotherapy ; Pneumoconiosis ; metabolism ; therapy ; Quality of Life ; Treatment Outcome

Adult ; Burns ; etiology ; Humans ; Male ; Middle Aged ; Paraquat ; adverse effects ; Scrotum ; injuries

Adult ; Asthma, Occupational ; therapy ; Bronchoalveolar Lavage ; Humans ; Male ; Textiles ; adverse effects

Foam Cells ; pathology ; Gastrointestinal Neoplasms ; pathology ; Humans

Objective To study the effect of Jade -Screen Powder (JSP)on regulating expression of 5 microRNAs associated with helper T cells in asthmatic mouse model.Methods Forty Balb /c mice were randomly di-vided into 4 groups,1 0 mice for each group,namely normal control,asthma model,JSP treatment and Dexamethasone treatment.The mouse models of allergic inflammation on both upper and lower airways were established by ovalbumin sensitization and challenge.Interleukin(IL)-1 3 and IL -1 7 expressions were detected from lung homogenates by ELISA.Hematoxylin and eosin staining was also performed to observe the pathological changes in the lung tissue.The expressions of miR -1 46a,miR -1 46b,miR -21 0,miR -1 26 and miR -21 a were detected by quantitative real time PCR from splenocytes.Results The lower levels of IL -1 3 [(6.382 ±1 .690)μg/L]and IL -1 7 [(24.21 2 ± 1 .250)μg/L]were found in JSP treatment group compared with those in the asthma model group [(20.1 54 ±7.960)μg/L;(50.31 2 ±5.770)μg/L,rseparately],there was significant difference in IL -1 3 between JSP group and the asthma model group,as well as IL -1 7 (t =3.785,P =0.005;t =9.891 ,P =0.000).Same findings were found in Dexamethasone treated group as well [IL -1 3:(9.366 ±3.460)μg/L,IL -1 7:(29.1 32 ±4.960)μg/L;t =2.779, P =0.024;t =6.225,P =0.000].However,upregulation of miR -21 0 was observed in JSP treatment group (2.052 ± 0.871 )compared with that in the asthma model group (4.034 ±1 .379)(3.95 folds,t =2.71 8,P =0.026).Mean-time,the expression of miR -1 26 in JSP group (4.920 ±0.924)and Dexamethasone group (3.862 ±1 .51 0)in-creased compared with asthma model group (6.024 ±0.447)(2.1 5 folds,t =2.405,P =0.043,and 4.48 folds,t =-3.069,P =0.01 5).Conclusions Th2 and Th1 7 T cells participate in the pathogenesis of asthma and the asthmatic process can be inhibited by JSP.JSP may affect the helper T cells by regulating miR -21 0 and miR -1 26.