Hemangiopericytoma is a relatively uncommon vascular tumor. It was first described by Stout and Murray in 1942. Here, we report a case of a primary prostatic hemangiopericytoma, which has been reported approximately <10 cases. This may be the first case of a prostatic hemangiopericytoma in Korea. A 35-year-old male patient presented with an episode of dysuria and perineal discomfort over the past 3 months. The radiological and histological features indicated a malignant hemangiopericytoma. Systemic chemotherapy was selected as the primary treatment. After 5 cycles of chemotherapy, the size of masses of the prostate and lung decreased. Four months after then, the patient died from hemoptysis.
Adult ; Drug Therapy ; Dysuria ; Hemangiopericytoma* ; Hemoptysis ; Humans ; Korea ; Lung ; Male ; Prostate

Hemangiopericytoma is a relatively uncommon vascular tumor. It was first described by Stout and Murray in 1942. Here, we report a case of a primary prostatic hemangiopericytoma, which has been reported approximately <10 cases. This may be the first case of a prostatic hemangiopericytoma in Korea. A 35-year-old male patient presented with an episode of dysuria and perineal discomfort over the past 3 months. The radiological and histological features indicated a malignant hemangiopericytoma. Systemic chemotherapy was selected as the primary treatment. After 5 cycles of chemotherapy, the size of masses of the prostate and lung decreased. Four months after then, the patient died from hemoptysis.
Adult ; Drug Therapy ; Dysuria ; Hemangiopericytoma* ; Hemoptysis ; Humans ; Korea ; Lung ; Male ; Prostate

We retrospectively reviewed eleven patients with advanced bladder carcinoma (T3b-4) who were treated with methotrexate, vinblastine, doxorubicin and cisplatin (M-VAC) chemotherapy alone. 1. The mean age and the cycle were 64 years ( 50-75) and 4.7 cycles ( 1-II) respectively. 2. In primary lesions, four (36.4 per cent) showed partial response, six (54.5 per cent) minor response and one (9.1 per cent) clinically stable, and therefore response rate was 36.4 per cent. There was no case of complete remission. In extravesical lesions, progression was seen in a case of liver metastasis and no remarkable changes was seen in bone metastatic case. 3. Maximal effect of clinical response was observed after completion of 3-4 cycles in cases of partial remission. 4. There were marked improvement of clinical symptoms such as loss of hematuria and dysuria during 1 or 2 cycles of chemotherapy. Even though there was no case of complete remission in our cases, 3-4 cycles of M-VAC monotherapy may be considered as a kind of treatment of the advanced transitional cell carcinoma or bladder in selected cases.
Carcinoma, Transitional Cell* ; Cisplatin ; Doxorubicin ; Drug Therapy ; Dysuria ; Hematuria ; Humans ; Liver ; Methotrexate ; Neoplasm Metastasis ; Retrospective Studies ; Urinary Bladder* ; Vinblastine

Although it has been estimated that from 90 to 95% of all vesical neoplasms are of epithelial origin, and about 80% or more of carcinomas of the bladder are of transitional cell type, pratically all of the other constituents of the bladder have been known to give rise to benign and malignant tumors. A clinical observation was made on the non-transitional cell bladder tumors of the patients in the department of urology, Seoul National University Hospital during the period from 1966 to April, 1976. The following results were obtained: 1) During the period, 3699 patients were hospitalized, there were 293 cases of bladder tumors giving a rate of 7.9%. 2) Among 187 cases of bladder tumors there were 15 cases of non-transitional bladder tumors with a rate of 8%. 3) Age distribution was between 28 and 76 years. 4) Following symptoms could be found, hematuria in 93%, frequency 40%, dysuria 33% and other symptoms. 5) Squamous cell carcinoma was observed on 8 cases (4.3%), adenocarcinoma 3(1. 6%), metastatic carcinoma 2 (1.0%), malignant lymphoma 1 (0.5%). 6) Segmental resection was performed in 5 cases, total cystectomy 4, TUC 2 cases. Radiation and chemotherapy were combined in special cases. 7) 3 patients with squamous cell carcinoma died within 1 year after treatment.
Adenocarcinoma ; Age Distribution ; Carcinoma, Squamous Cell ; Cystectomy ; Drug Therapy ; Dysuria ; Hematuria ; Humans ; Lymphoma ; Seoul ; Urinary Bladder Neoplasms* ; Urinary Bladder* ; Urology

A clinical and statistical study was made on 196 cases of urinary tract tuberculosis seen during the period from January 1972 to December 1976. The results are summarized as follows: 1) Of the 196 patients, the most frequent age group was 21-40 years old, giving ratio of 64.8% 2) Sex distribution of male to female was 1.3 : 1. 3) The most frequent finding of urine was pyuria(88. 5%), in order of hematuria(79.6%) and proteinuria(82. 2%). The most common symptom was frequency, in order of dysuria, flank pain and scrotal pain. 4) By acid-fast stain and culture of urine, tubercle bacilli were demonstrated in 52.6% cases. 5) According to the result of urinary finding during chemotherapy, tubercle bacilli were not detected in 64.3% after chemotherapy for 6 months, and in 80 % after chemotherapy over 6 months. 6) The involved genitourinary tuberculosis were kidney(76. 9%). ureter(26.9%) and epididymis (11. 5%). 7) Tuberculosis in other organ combined with G-U tract Tb were 42.3%, such as pulmonary tuberculosis(30. 7%), pleura(6.4%) and lymph-node(2.6%) and pulmonary tuberculosis with urinary tuberculosis patients were 7.2%. 8) The positive roentogenographic finding in positive urine AFB was 75.6% and negative urine AFB was 86.5%.
Drug Therapy ; Dysuria ; Epididymis ; Female ; Flank Pain ; Humans ; Male ; Sex Distribution ; Statistics as Topic ; Tuberculosis* ; Tuberculosis, Pulmonary ; Urinary Tract*

A clinical observation was made on 46 cases of renal tuberculosis who were admitted to the Department of Urology, Eul Ji General Hospital, Seoul, Korea, during the period from January 1978 to December 1982. Following results were obtained. 1. The most common symptoms were urinary frequency (47.8%), gross hematuria (43.5%) flank pain (32.6%) and dysuria (21.7%). 2. Tubercle bacilli were demonstrated in 37% of patients by Ziehl-Neelson staining. The most common findings of urine were hematuria (73.9%), Pyuria (54.4%) and proteinuria (32.6%). 3. Excretory urographic findings in 46 cases of renal tuberculosis were non visualization (45.7%), calyectasis (28.3%), delayed visualization (15.2%), ureteral deformity (10.9%). 4. The most common finding of cystoscopy was hemorrhagic patches (44.4%), followed by sealed off ureteral orifice (s) in 30.6%, ulceration and tubercle formation in 25.0%. 5. Patients were managed by chemotherapy only in 47.8%, chemotherapy with nephrectomy in 43.5%, chemotherapy with reconstructive surgery in 8.7%.
Congenital Abnormalities ; Cystoscopy ; Drug Therapy ; Dysuria ; Flank Pain ; Hematuria ; Hospitals, General ; Humans ; Korea ; Nephrectomy ; Proteinuria ; Pyuria ; Seoul ; Tuberculosis, Renal* ; Ulcer ; Ureter ; Urology

We describe a 56-year-old man who developed an acute liver injury after taking alfuzosin for 1 month to control his newly diagnosed benign prostatic hypertrophy (BPH). There was no history of alcohol consumption or the taking herbal or traditional remedies. Viral causes, autoimmune hepatitis, and biliary tree obstruction were excluded. Other rare causes of hepatitis such as hemochromatosis, primary biliary cirrhosis and Wilson's disease were also absent in this patient. His liver test results began to improve after discontinuing the alfuzosin. Two weeks later, alfuzosin was administered again because the patient complained of dysuria. After 10 days of alfuzosin reuse, his liver test results worsened. Five months later after the complete discontinuation of the drug, his liver test results had returned to normal. This clinical sequence suggests that alfuzosin caused his acute liver injury.
Acute Disease ; Adrenergic alpha-Antagonists/*adverse effects ; Dysuria/pathology ; Humans ; Liver Diseases/*chemically induced/pathology ; Liver Function Tests ; Male ; Middle Aged ; Prostatic Hyperplasia/drug therapy ; Quinazolines/*adverse effects

Statistical observation was made on 117 cases of malignant tumors in the urinary tract who had been admitted to Department of the Urology, St. Mary's Hospital from January 1, 1966 to May 31. 1972. Statistical observation included age, sex, clinical manifestation, annual distribution, organ distribution and methods of operation. The results were as follows; 1. Male patients were more common than female patients, and most of them were over the age of 40 years. Hematuria was the most common symptom, and other symptoms were pain, mass and dysuria. Operations were performed in 79 patients, and remaining patients were treated with radiation, chemotherapy and hormone therapy. 2. The urinary bladder was the most commonly involved organ, and other organs were in order of kidney, prostate and penis. Histologically, transitional cell carcinoma in the bladder was the most common and next in order was of renal cell carcinoma, Wilms' tumor and squamous cell carcinoma of penis.
Carcinoma, Renal Cell ; Carcinoma, Squamous Cell ; Carcinoma, Transitional Cell ; Drug Therapy ; Dysuria ; Female ; Hematuria ; Humans ; Kidney ; Male ; Penis ; Prostate ; Urinary Bladder ; Urinary Tract* ; Urology ; Wilms Tumor

A clinical observation was made on the patients with bladder tumor admitted to the Department of Urology, Seoul Adventist Hospital during the periods from January 1978 to December 1981. The following results were obtained. 1. During the periods, 930 patients were hospitalized, and there were 36 cases of bladder tumor giving an incidence rate of 3.9%. 2. There were 25 males and 11 females with a ratio of 2.3:1. 3. Age distribution was between 23 and 77 years, the highest incidence rate was in the age group of 60-69years. 4. The clinical manifestation included gross hematuria (88.9%), frequency (69.4%), dysuria (44.4%) and the others. 5. On I.V.P. findings, 29 cases (80.6%) revealed normal upper tract, 6 cases (16.7%) were unilateral hydronephrosis, and 31 cases (86.1%) revealed filling defect in the bladder. 6. The tumors were located mainly at the lateral wall and trigonal area of bladder (50.0%). 7. Of 36 cases of bladder tumor, 30 cases (83.3%) were transitional cell carcinoma, 3 cases (8.3%) squamouscell carcinoma, and each 1 case (2.8%) adenocarcinoma, metastatic carcinoma and leiomyoma. 8. Among 36 cases, T.U.R. was performed in 17 cases, and intravesiCal chemotherapy in 11 cases. 9. Of 11 patients who received intravesical chemotherapy, 6 were recurred within 1 year showing a recurrencerate of 54.5%.
Adenocarcinoma ; Age Distribution ; Carcinoma, Transitional Cell ; Drug Therapy ; Dysuria ; Female ; Hematuria ; Humans ; Hydronephrosis ; Incidence ; Leiomyoma ; Male ; Seoul ; Urinary Bladder Neoplasms* ; Urinary Bladder* ; Urology

A clinical observation was made on 60 cases of genitourinary tract tuberculosis who were admitted to National Medical Center during the period from January 1976 through December 1980. Following results were obtained 1. Incidence of genitourinary tract tuberculosis was 6% of all in patients. 2. Most frequent symptoms was those of vesical symptoms such as frequency (53.3%), hematuria (55%) and dysuria (28.3%). 3. Tuberculosis in other combined with genitourinary tract tuberculosis were such as pulmonary tuberculosis (38.3%), pleurisy (5%), spine tuberculosis (3.3%) and tuberculous intestinal fistula (3.3%). 4. Tuberculous epididymitis without radiographic evidence of tuberculous invasion were 12 cases among the patients. 5. The most frequent finding of urine was pyuria (45%) , hematuria (45%) and proteinuria (33.3%). 6. Tubercle bacilli were demonstrated by staining in 26.6%. 7. Excretory urographic findings in 60 cases of renal tuberculosis were non visualization (50%). calyectasis (26.6%). delayed visualization (21.6%), ureteral abnormality (21%) and contracted bladder (15%). 8. Patients were managed by chemotherapy only in 20%, chemotherapy with nephrectomy in 38.3% and chemotherapy with reconstructive surgery in 20%.
Drug Therapy ; Dysuria ; Epididymitis ; Hematuria ; Humans ; Incidence ; Intestinal Fistula ; Male ; Nephrectomy ; Pleurisy ; Proteinuria ; Pyuria ; Spine ; Tuberculosis* ; Tuberculosis, Pulmonary ; Tuberculosis, Renal ; Ureter ; Urinary Bladder