No abstract available.
Dysgerminoma*

No abstract available.
Dysgerminoma*

No abstract available.
Dysgerminoma* ; Teratoma*

No abstract available.
Dysgerminoma* ; Female ; Ovary* ; Pregnancy*

No abstract available.
Dysgerminoma* ; Female ; Ovary*

Complete gonadal dysgenesis with 46,XY karyotype is a clinical condition characterized by the absence of testicular tissue but typical Mullerian structures in a phenotypically female individual. The condition presents as primary amenorrhoea or delayed puberty. Eventually, malignant neoplasms may arise. We report a case of a 16-year-old patient with Swyer syndrome presenting with primary amenorrhoea and with previous diagnosis four years earlier of a malignant dysgerminoma in the right ovary.
Swyer syndrome ; dysgerminoma ; gonadal dysgenesis

Dysgerminoma comprises 3%–5% among ovarian malignancies, mostly seen in adolescent and early adult women. The recurrence rate is approximately 10%–20%, occurring within 2 years of diagnosis, and has been reported that more than 75% occur in the 1st year. A 19‑year‑old nulligravid initially presented with severe abdominal pain, who underwent emergency exploratory laparotomy and left salpingo‑oophorectomy, whose histopathologic result revealed dysgerminoma, Stage IC2. Recurrence of dysgerminoma was noted on the contralateral ovary 10 months after for which she had undergone another surgery for wedge resection of the right ovarian mass and complete surgical staging. She received adjuvant chemotherapy without complications. Despite two consecutive surgeries and chemotherapy, she had conceived naturally and her pregnancy was carried to term with no complications and delivered to a live baby girl by normal spontaneous delivery. This case is a proof of how fertility‑sparing surgeries and chemotherapy in dysgerminoma can successfully preserve reproductive functions for future conceptions.
Chemotherapy, Adjuvant ; Dysgerminoma ; Pregnancy ; Recurrence

In 5 years (1994-1998), 168 patients with ovarian germ cell tumors were diagnosed and treated in HCM city Cancer Hospital. Ovarian germ cell tumor is a rare disease. These tumors were often detected in early stage (61.2% in stage I, among them 39.6% in stage IA). The tumor marker AFP plays an important role in diagnosis and follow-up the disease. AFP was positive in 60% cases of malignant germ cell tumors, among them 55.6% were immature teratomas, and AFP was negative in dysgerminoma. The rate of teratomas was highest: 53%, rate of dysgerminoma: 19%, endodermal sinus tumor 14.9%, embryonal carcinoma 9.5% and mixed forms 3.6%. It’s necessary to emphasize the role of preservative surgery in the treatment of these tumors
Ovarian Neoplasms ; alpha-Fetoproteins ; Dysgerminoma ; diagnosis ; therapeutics ;

45X/47XYY mosaicism is a very rare sex chromosomal disorder with limited clinical information. We experienced an unusual mosaic syndrome in a 16-year old woman with a phenotypic female, short stature, and immature secondary sexual characteristics. We performed both gonadectomy and found a gonadoblastoma in one gonad and dysgerminoma in another gonad.
Adolescent ; Chromosome Disorders ; Dysgerminoma* ; Female ; Gonadoblastoma* ; Gonads ; Humans ; Mosaicism

Adult ; Dysgerminoma ; pathology ; Female ; Humans ; Ovarian Neoplasms ; pathology