The hepatoprotective effect against carbone tetrachloride-induced liver was demonstrated in mice. Aqueous and methanol extract of ML root at the dose of 10mg/kg/day had reduced the serum ALT enzyme activity, bilirubine level and hepatic malonyl dialdehyd in mice. Methanol extract exerts high antioxydant effect, it inhibited CCl4 toxicity. Macroscopic and microscopic structure images of liver damage were improved obviously, restoration was noted
Plants, Medicinal ; liver ; Plant Roots

Methanol total dried extract of the root of Nho dong (Morinda longissima Y.Z.Ruan, Rubiaceae) collected in Chieng An commune, Son La town, Son La province was analyzed. From the fractions n.6 and n.18 of column chromatography with Silicagel adsorption and developing solvents Chloroform/Methanol (9/1) system, by thin layer chromatography, an anthranoid substance (CP4) was isolated. Spectral analysis showed its structure as its is 1,3- dihydroxy,4-methyl ethyl ether anthraquinone, first time found in nho dong
Anthraquinones ; Medicine, Traditional ; plants, medicinal ; Plant Roots ;

The authors studied total dry extract of roots of Nho dong – a valuable herb that Thai ethnic used to treat liver diseases, colitis and oedema. Roots collected at Chieng An commune, Son La town, Son La province. Isolating chemical components by column chromatography and thin layer chromatography, authors collected a substance called CP3. Results of spectral analyses by UV, IR, MS, and NMR techniques showed that CP3 was emodin
Medicine, Traditional ; Emodin ; Plant Roots

Background: Breast cancer is typically detected in women with a standard prevalence categorized by age of 80.1/100.000 people in the world. In Vietnam, the proportion for women was 17.4/100.000 people in 2000. The value of ultrasound has been acknowledged in the last few decades. However, there is an existing problem related to the proportion of inaccurate diagnosis (amounted to 10-20%), or suspect diagnosis. Thus, the diagnosis of breast cancer employing ultrasound (US) method not only overcomes the above obstacles, but also generates a number of advantages. \r\n', u'Objectives: To study the value of US and US lesions in the diagnostic for breast cancer. \r\n', u'Subjects and method: 621 patients with breast abnormalities were diagnosed and treated at K-hospital from 2003 to 2006. They underwent breast US scanning. The sonographic features were compared with pathologic results. \r\n', u'Results: Common signals of breast cancer: the mass of irregular shape: Se = 73.9%, Sp = 87; speculation margins: Se = 72.4%, Sp = 96.8%; hypoechoic mass: Se = 89.5%, Sp = 83.3%; heteroechoic density: Se = 98%, Sp = 68.5%. Other uncommon signals are: punctuate hyperechogenics of calcifications, acoustic shadow behinds the mass, the number of punctuate hyperechogenic > 5. The D/W index > 1: PPV = 95.9%. \r\n', u'Conclusion: Ultrasound is a valuable method for breast cancer diagnosis with Se = 89.47%, Sp = 86.49%, PPV = 92.96%, NPV = 83.72% and Acc = 88.41%.\r\n', u'
Breast cancer ; diagnosis ; Sonography

Geographical and racial factors constitute important distinctions between Kawasaki disease (KD) and multisystem inflammatory syndrome in children (MIS-C), but no study has been conducted in Vietnam. Forty-one children with KD from January 2018 to July 2020 and 42 with KD/MIS-C from August 2020 to December 2022 were included in this study. Of the patients, 52.3% were aged between 12 and 35 months. Only two were aged over 5 years, and both were belong to the KD/MIS-C group. A 59.5% of the patients were male. Apart from fever, all symptoms tended to be more frequent in patients with KD/MIS-C. The prevalence of diffuse skin rash, hand and foot edema or erythema and gastrointestinal signs was significantly higher in patients hospitalized with KD/MIS-C. There was no significant difference in laboratory findings between the two groups. Coronary artery dilation was more frequently observed in patients with KD/MIS-C compared to those with KD (40.5% vs. 14.6%, P = 0.009).

Background: Coordinating between soldiers and people bring significant results in protecting healthy for soldiers and people in malaria epidemic area.\r\n', u'Objectives: To evaluate epidemic supervision and propose solutions protecting healthy for soldiers and people in malaria epidemic area.\r\n', u'Subjects and methods: A retrospective cross sectional study was carried out on two provinces Binh Phuoc and Dak Lak\r\n', u'Results: there was 4 main disease types were fever, tuberculosis, diarrhea and malaria. Malaria at investigated times still accounted high rate comparing with general fever rate. Malaria risk contained in people living or working in forest and mountain field; free emigrants; armed forces and border guard. These subjects needed to improve regularly protection from malaria. Communication of health education is one of important method to prevent and control malaria.\r\n', u'Conclusion: It is necessary to implement strong methods (such as providing insecticide treated bed nets, indoor residual spray) to prevent and control malaria. \r\n', u'
Epidemic supervision ; healthy ; soldier ; malaria epidemic area.

Blepharoplasty is one of the most commonly performed aesthetic procedures. Surgical complications are rare, but can have severe consequences, such as permanent vision loss. In this report, we describe a patient who developed primary angle-closure glaucoma (ACG) with associated vision loss after a oculoplastic procedure using local anesthesia. So far, six similar cases have been described in the literature. It is believed that acute ACG is triggered by the surgical procedure in patients with predisposing risk factors such as a cataract. Surgical triggering factors include the use of buffered lidocaine/xylocaine with adrenaline/epinephrine, stress, and coverage of the eyes postoperatively. Due to postoperative analgesic use, the clinical presentation can be mild and atypical, leading to a significant diagnostic delay. Acute ACG should therefore be excluded in each patient with postoperative complaints by assessing pupillary reactions. If a fixed mid-wide pupil is observed in an ophthalmologic examination, an immediate ophthalmology referral is warranted. Surgeons should be aware of this rare complication in order to offer treatment at an early stage and to minimize the chance of irreversible vision loss.
Anesthesia, Local ; Blepharoplasty* ; Blindness ; Cataract ; Glaucoma ; Glaucoma, Angle-Closure* ; Humans ; Ophthalmology ; Postoperative Complications ; Pupil ; Referral and Consultation ; Risk Factors ; Surgeons