1.Multimodal Hallucination (Audio-visual, Kinaesthetic and Scenic) Associated with the Use of Zolpidem.
Dushad RAM ; Najla EIMAN ; Basavana GOWDAPPA
Clinical Psychopharmacology and Neuroscience 2015;13(2):215-217
We are reporting a case of zolpidem induced multimodal hallucinations in a 22 year old female without any history of psychiatric disorders. Zolpidem, by acting on gamma-amino butyric acid type A receptor has a potential to cause a paradoxical reaction and there also exists a possibility of an induced delirium with its use. This case reports evaluates its potential to cause multimodal hallucinations. Zolpidem needs to be prescribed judiciously with the caution of potential side effects particularly in females.
Butyric Acid
;
Delirium
;
Female
;
Hallucinations*
;
Humans
;
Sleep Initiation and Maintenance Disorders
2.Atomoxetine Augmentation in a Case of Treatment Resistant Panic Disorder with Multiple Augments Failure: A Case Report.
Dushad RAM ; Shwetha PATIL ; Basavana GOWDAPPA ; Iyshwarya RAJALAKSHMI
Clinical Psychopharmacology and Neuroscience 2015;13(3):321-323
Atomoxetine, a selective norepinephrine inhibitor, is effective in comorbid anxiety and attention deficit hyperactivity disorder, however its role in panic disorder is unknown. We are presenting a case of panic disorder, who initially partially responded to clonazepam. When clonazepam was added with sertraline, escitalopram, desvenlafaxin, she did not improve significantly until paroxetine was added. When clonazepam-paroxetine combination was added with propranolol, etizolam, olanzepine, risperidone and amisulpride the symptom remission did not occur until a trial of Atomoxetine was done.
Anxiety
;
Attention Deficit Disorder with Hyperactivity
;
Citalopram
;
Clonazepam
;
Norepinephrine
;
Panic Disorder*
;
Panic*
;
Paroxetine
;
Propranolol
;
Risperidone
;
Sertraline
;
Atomoxetine Hydrochloride
3.Diagnostic approach and use of CTPA in patients with suspected pulmonary embolism in an emergency department in Saudi Arabia
Feras ALMARSHAD ; Ali ALAKLABI ; Abdulrahman Al RAIZAH ; Yousof ALZAHRANI ; Somaya Awad ALJOHANI ; Rawaby Khalid ALSHAMMARI ; Al-zahraa Saleh AL-MAHLAWI ; Abdulaziz Abdullah ALAHMARY ; Mosaad ALMEGREN ; Dushad RAM
Blood Research 2023;58(1):51-60
Background:
In patients with suspected pulmonary embolism (PE), the literature suggests the overuse of computerized tomography pulmonary angiography (CTPA) and underuse of clinical decision rules before imaging request. This study determined the potential for avoidable CTPA using the modified Wells score (mWS) and D-dimer assay in patients with suspected PE.
Methods:
This hospital-based retrospective study analyzed the clinical data of 661 consecutive patients with suspected PE who underwent CTPA in the emergency department of a tertiary hospital for the use of a clinical prediction rule (mWS) and D-dimer assay. The score was calculated retrospectively from the available data in the files of patients who did not have a documented clinical prediction rule. Overuse (avoidable) CTPA was defined as D-dimer negativity and PE unlikely for this study.
Results:
Of 661 patients’ data examined, clinical prediction rules were documented in 15 (2.3%).In total, 422 patients (63.8%) had required information on modified Wells criteria and D-dimer assays and were included for further analysis. PE on CTPA was present in 22 (5.21%) of PE unlikely (mWS ≤4) and 1 (0.24%) of D-dimer negative patients. Thirty patients (7.11%) met the avoidable CTPA (DD negative+PE unlikely) criteria, and it was significantly associated with dyspnea. The value of sensitivity of avoidable CTPA was 100%, whereas the positive predictive value was 90.3%.
Conclusion
Underutilization of clinical prediction rules before prescribing CTPA is common in emergency departments. Therefore, a mandatory policy should be implemented regarding the evaluation of avoidable CTPA imaging to reduce CTPA overuse.