1.Immunostimulating effect of “M” capsule on nasopalatine cancer (NPC) patients after radiotherapy
Journal of Medical Research 2002;18(2):3-9
M capsules are applied to treat NPC after radiotherapy. In comparision with 28 NPC patients who are do not use M capsules we have some remarks: the number of white blood cells, lymphocytes and lymphocyte subset increase faster and remain more stable, and there is a decrease of IgA/VCA titre lower and more stable in patients who used M capsules in comparision with those in the control group. In the using M capsules group we find that the number of patients who survive over three years increase as well as the metastasis rate. This result shows that M capsule might have effecting rising the number of white blood cells in NPC patients who got treated radiotherapy, and help lasting the life of the NPC patients.
Radiotherapy
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Blood Cells
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Adjuvants, Immunologic
;
neoplasms
2.Dynamic of immunobiological parameters and their prognostic values on nasopharyngeal carcinoma (NPC) patients
Journal of Medical Research 2000;12(2):13-20
Studying the dynamy of immunobiological parameters after radiotherapy and estimating its prognostic values on 77 NPC patients with T1-3No-3Mo (UICC 1979) at Hanoi K hospital from 11/1994 to 12/1998. We have some results: The prognostic values have been found significantly in the quantity of leukocytes, the level of serum IgA/VCA, IgG/EBNA before radiotherapy, the frequency of HLA antigens A11, A2, B17 and the desequilibre linkage A11-B17, A2-B17. Especially, the increase of serum IgA/VCA after radiotherapy has significantly predicted recurrence of studied NPC patients
Nasopharyngeal Neoplasms
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Nasopharyngeal Diseases
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Radiotherapy
3.Prevalence and risk factors of the limitations in daily activities in the elderly
Giang Ngan Pham ; Dung Viet Truong ; Liem Chi Tran ; Hoat Ngoc Luu
Journal of Medical Research 2008;59(6):88-93
Background: Limitation of daily activities is the obstacle that prevents the elderly from achieving their desires. Objective: Aim to discover the prevalence and risk factors of the limitation in daily activities in the elderly. Subject and methods: This cross - sectional study was conducted in 4 provinces: Thai Nguyen, Ha Tay, Hue and Can Tho during June to December 2006 among 2.644 people at the age of 60 and above. Results: The overall prevalence of limitation of the elderly is 5.6%, and 4.3% is totally dependent and 1.3% is partly dependent. This proportion increases with age. It happens more in urban areas as opposed to rural and mountainous areas. Those living with their spouse have lower proportion of limitations. Can Tho and Ha Tay has the higher proportion of limitation than Hue and Thai Nguyen. Factors related to these limitations are aging (OR = 1.08; 1.06-1.10), not working at the current time (OR = 0.11; 0.05-0.28), ethnicity (OR = 2.25; 1.45-3.49), lack of physical exercise (OR = 2.24, 1.75-3.85), brain damage (OR = 15.18; 9.47-24.35), dementia (OR = 2.39; 1.62-3.54) and loss of vision (OR =1.32; 1.05-1.65). Conclusion: The limitation in daily activities tremendously affects the quality of life for the elderly. Age, working status, race, physical activity, accident of cerebral vessels, dementia and vision loss are statistic significant related factors for the limitation in daily activities of the elderly
Elderly
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daily activities
4.Investigation of hemostatic disorders in patients with congenital heart diseases undergoing open heart surgery at Hue Central Hospital
Sang Si Dong ; Minh Ngoc Nguyen ; Hoa Thi Thuy Phan ; Thuan Thi Nguyen ; Dung Thi Tran ; Hanh Phuoc Huynh
Journal of Medical Research 2007;51(4):55-62
Background: Open heart surgery with cardiopulmonary bypass (CPB) causes haemostatic abnormalities which result in postoperative excessive bleeding. Objectives: To investigate haemostatic disorders before - after CPB and postoperative bleeding. Subjects and methods: Sixty congenital cardiac patients with and without cyanosis were recruited consecutively. Hematology and coagulation tests were done 1 day before operation, 15 minutes after protamine administration, 2 and 6 hours after the operation in the intensive care unit (lCU). Mediastinal chest tube drainage (MCTO) was measured for the first 6h in the ICU. Results: Significant differences between 2 groups could be found for red blood cells, hemoglobin, hematocrit, fibrinogen, D-dimer, fibrinogen degradation products (FOP), von Kaulla and platelet aggregation to epinephrine before operation (p < 0.05). There were not significant differences in platelets, PT, APTT, platelet aggregation to adenosine diphosphate (AOP) in the acyanotic and cyanotic patients (p > 0.05). Most hematology parameters were decreased significantly and hemostasis measurements were prolonged after operation in both groups (p < 0.05). There was also the significant difference in MCTO between 2 groups (p < 0.05). Conclusion: Coagulation, hemostasis and fibrinolysis disorders; thrombocytopenia and acquired transient platelet dysfunction may be responsible for bleeding complications after CBP \r\n', u'\r\n', u'
Heart Defects
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Congenital/ pathology
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epidemiology
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Hemostatic Disorders/ pathology
;
diagnosis
5.Morbidity and mortality of acute respiratory infections in Thai Binh province, Vietnam, 2002-2005
Hien Tran Nguyen ; Dinh Ngoc Pham ; Dung Chi Tham ; Hoa Thuy Nguyen ; Dung Kim Thanh ; Chung Thanh Nguyen ; Diu Van Pham ; Kiyosu Taniguchi
Journal of Preventive Medicine 2008;96(4):5-12
Background: Acute Respiratory Infection (ARI) is a common disease in developing countries. Morbidity and mortality of ARI are high, especially among children under 15 years old. Objectives: To describe socio-graphic factors, seasonal patterns, risky areas and determine the morbidity and mortality rates of acute respiratory infections in Thai Binh province. Subjects and method: This retrospective study reviewed the medical records of 4,585 hospital admitted patients who were diagnosed with ARI including upper and lower respiratory infections such as sore throat, pharyngitis, bronchitis, pneumonia and bronchitis-pneumonia at 8 district hospitals and 1 provincial hospital in Thai Binh province during 2002-2005. The selected medical records were based on the available check list and two standard screening tests. Results:Morbidity and mortality of ARI in Thai Binh province were 61.6 and 0.52, respectively. ARI mainly occurred among children under 5 years old, of which the highest mortality was among those under 12 months of age. Male children were at higher risk of acquiring ARI, but less prone to death than female. Occupation did not significantly associate with the risk of ARI. The morbidity increased sharply during inter-season, e.g. March and October. Thai Binh city, Kien Xuong and Tien Hai district were reported with the highest morbidity in accompany of the high mortality as consequences. Conclusion: The prevention and control methods were recommended to annually focus on the male children aged less than 5 years old during March and October in Thai Binh city, Kien Xuong and Tien Hai district.
morbidity
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mortality
;
acute respiratory infections
6.Epidemiological characteristics of HIV/AIDS patients and community care in Thua Thien Hue
Ngoc Thi Tran ; Son Dinh Nguyen ; Minh Quang Duong ; Hoa Thai Nguyen ; Tam Le Nguyen ; Son Van Ly ; Son Huu Le ; Dung My Tran ; Hao Van Huynh
Journal of Preventive Medicine 2007;17(4):39-44
Background: HIV/AIDS pandemic really become danger to mankind on the earth. Objectives: Description epidemiological characteristics of HIV/AIDS patients. Studying clinical expression, learning aboutdemands of infected patients and community care for infected patients. Subjects and method: 71 HIV/AIDS people in Thua Thien Hue were studied in 2006. Using descriptive method to give epidemiological characteristics and behaviour of HIV/AIDS people. People were determined HIV/AIDS infection based on the criteria of Ministry of Health. The information were collected by target study. Results: HIV/AIDS people mainly from the age of 20 to 39 (83,10%), males were 52,10% and in various levels of education and all kinds of occupation. The rate of sexually transmitted infection was 84,5% and infection transmission was 15,5%. The rate of sexually transmitted infection within the last 12 months was 57,7%. 63,4% of infected people used condom while having sex with their spouses or partners. 1,4% of infected people using drug infection within the last month. 38% of the infected people had manifestations of AIDS, 77,8% of HIV/AIDS were treated with antiviral drugs. Families and communities had positive attitudes and behaviors to the HIV/AIDS people. Infected people being remoted from the society was 12,7%, 88,7% of them receiving supports from their communities such as disease treatment, spirit and material supports and job opportunities. Conclusion: Strengthen communication activities to change behavior of HIV/AIDS people and in communitiy to reduce alienation, discrimination for infected people. Execute socialization in care and support for HIV/AIDS people.
HIV/ immunology
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isolation &
;
purification
;
pathogenicity
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Community Health Services/ organization &
;
administration
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Epidemiologic Methods
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7.Situation of extremity injury caused by traffic accident in Viet Duc hospital from 2000 to 2004
Dung Trung Tran ; Hoa Ngoc Pham ; Toan Van Ngo ; Thach Van Nguyen ; Thuy Xuan Nguyen ; Quan Viet Doan ; Phuoc Van Nguyen
Journal of Surgery 2007;57(1):97-102
Background: Situation of extremity injury caused by traffic accidents and occupational accidents are increasing in Vietnam. Therefore, the prevention and fight against these accidents are one of the key objectives to reduce the burden on the families of victims as well as for society. Objectives: To outline situation of extremity injury patients caused by traffic accident, treated in Viet Duc hospital from 2000-2004. Subjects and method: A retrospective study was conducted on 19.845 patients (14.562 males, 5.283 females, aged from 1-97 years old). The subjects were divided into 3 main groups: alone upper extremity injury, alone lower extremity injury and multiple fractures. Results: Extremity injury was common seen in people of working age (78.1%), men more than women (2.76/1 ratio), left foot more than right foot and it was common been in multiple fracture situation due to complex mechanisms of injury (50.3%), alone extremity injury (49.7%). The lower extremity injury was more common seen than upper extremity injury. Open fracture injury (27.3%), in which open fractures in lower extremity were more common seen. Open fractures in both 2 leg bones was the most common seen, accounted for 57.4% among total of open fractures. Amputation accounted for 8.3% among all case of open fractures and 2.3% among all case of extremity injuries. Conclusion: Extremity injury (lower extremity and upper extremity) caused by traffic accidents is common seen. The average, there are 3 emergency surgeries due to open fracture injury were performed daily in Viet Duc hospital per a total of about 11 traumatic emergency surgeries.
Fractures
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Bone
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Arm Injuries
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Leg Injuries
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Accidents
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Traffic
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8.The situation of HIV/AIDS infection of prisoners at Binh Dien prison from 2005-2006
Tam Le Nguyen ; Minh Quang Duong ; Hue Thanh Dinh ; Son Dinh Nguyen ; Ngoc Thi Tran ; Hoa Thai Nguyen ; Son Van Ly ; Son Huu Le ; Dung Thi My Tran ; Hung Chi Nguyen
Journal of Preventive Medicine 2007;17(4):45-50
Background: With the development of HIV/AIDS pandemic in community, amount of HIV/AIDS people more and more increase in prison. Objectives: Determine the rate of HIV/AIDS infection of prisoners at Binh Dien prison. Learning about related elements to HIV/AIDS infection. Subjects and method: Prisoners at Binh Dien prison. Method: 492 prisoners were chosen, interviewed directly and taken blood samples to HIV test. Using cross-sectional study on accidental samples. Techniques were used in this study: SERODIA-HIV and ELISA technique. Results: The rate of current HIV/AIDS infections was 21,74%, some HIV/AIDS related factors in the prison included sex, religion, income source, marrital status, common knowledge of HIV/AIDS, drug addiction history, needle sharing, sexually transmitted disease history, body tatoos and forskin inserted with metal balls, alcohol and beer drinking history, some factors such as: age and educational level were not associated with HIV/AIDS infection in prison. Conclusion: Strengthen interventional activities in prison to prevent HIV/AIDS spread between prisoners. To prisoners who were not infected HIV/AIDS: strengthen educational communication to they may prevent themselves from HIV/AIDS infection behaviors. To HIV/AIDS prisoners: Need to educate and consult especially to they have right behaviors, prevent HIV/AIDS spread for the others while they were in prison as well as they return to society.
HIV Infections/ blood
;
complications
;
epidemiology
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