2.Amplification of epidermal growth factor receptor gene in primary cervical cancer.
Korean Journal of Obstetrics and Gynecology 1993;36(7):1835-1848
No abstract available.
Epidermal Growth Factor*
;
Receptor, Epidermal Growth Factor*
;
Uterine Cervical Neoplasms*
3.Syphilis Prevalence in Young Men who want Oversea Employment.
Seong Bae PARK ; Jai Il YOUN ; Soo Duk LIM
Korean Journal of Dermatology 1980;18(6):539-544
Serologic tests for syphilis, including the qualitative and quantitative VDRL test and TPHA test, were carried out on 18, 151 healthy young men, who took a medical check-up for the overseas employment at Kyunghee University Hospital from April, 1978 to February, 1979. The syphilitics who revealed TPHA reactive, were given a questionare that dealt with three items. The results are summarized as follows. 1) The reactive rate of VDRL test was 3. 1% among 18, 151 healthy young men, 2) The biologic false positive rate of VDRL test was 7. 7% among the 520 men in whom TPHA test was carried out, using TPHA as standard. 3) The reactive rate of TPHA test was 2. 7% among 18, 109 men. On 42 men the TPHA test was not carried out. 4) With regard to the VDRL quantitative test, the reactive rate of the group with a titration of 1: 4 or lower was 85,2% out of 480 syphilitics. 5) In 480 syphilitics, 45. 8% (220) had a history of venereal 72.3%(347) had no general knowledge of syphilis, and 86. 2% (414) was unaware of his syphilitic infection.
Employment*
;
Humans
;
Male
;
Prevalence*
;
Serologic Tests
;
Syphilis*
4.The Findings of Cerebrospinal Fluids in 338 parients with Syphilis.
Seong Bae PARK ; Jai Il YOUN ; Soo Duk LIM
Korean Journal of Dermatology 1981;19(2):193-199
We examined cerebrospinal fluids of 338 patients with syphilis who underwent the routine physical examinations or visited out-patient skin clinic at Kyunghee University hospital from January, 1978 to December, 1979. They were diagnosed as syphilis only with serological tests such as VDRL and TPHA tests. The patients did not have any neurologic symptoms associated with syphilis or any other clinical syphilitic syrnptoms. They did not have any history of receiving antisyphilitic treatment. The VDRL test, cell count, protein value, sugar and chloride levels in cerebr-ospinal fluid were tested in these patients. The results were as follows. 1) CSF VDRL reactive rate was 2. 1% among 388 patients with syphilis. 2) CSF celI count was not less than 5/mm in 2 patients (28. 6%) among the 7 patients with syphilis, who showed the positive reactivity of CSF VDRL, and in 13 patients (3. 9%) among the 331 patients with syphilis who did not show the positive reactivity of CSF VDRL. 3) CSF protein level was more thnn 45ml/dl in 3 patients (42. 9%) among the 7 patients with syphilis who showed the positive reactivity of CSF VDRL anct ig, 65 patients (19. 6%) among the 331 patients with syphilis who did not show the positive reactivity of CSF VDRL. 4) Both CSF sugar and chloride levels were within norrnal limits in all of the 7 patients who showed the positive reactivity of CSF VDRL.
Cell Count
;
Cerebrospinal Fluid*
;
Humans
;
Neurologic Manifestations
;
Outpatients
;
Physical Examination
;
Serologic Tests
;
Skin
;
Syphilis*
5.A Case of Glassy Cell Carcinoma of the Uterine Cervix.
Chang Soo PARK ; Duk Soo BAE ; Je Ho LEE ; Jeong Sik KIM ; Jae Hong NOH
Korean Journal of Gynecologic Oncology and Colposcopy 2000;11(2):205-208
Glassy cell carcinoma (GCC) of the uterine cervix is a rare and highly malignant tumor, accounting for only 1%~2% of all cervical carcinomas. It is typically composed of malignant cells having a moderate amount of cytoplasm with "ground glass" appearance, distinct cell membranes that stain with eosin or periodic acid-Schiff, and large nuclei with prominent nucleoli. Since its original description in 1956 by Glucletmann and Cherry, 200 - 250 cases of GCC of the uterine cervix have been listed in the literature. We report here the clinicopathological study of one case of glassy cell carcinoma with brief review of the literature.
Cell Membrane
;
Cervix Uteri*
;
Cytoplasm
;
Eosine Yellowish-(YS)
;
Female
;
Prunus
7.Flow Cytometric Analysis of DNA patterns in Carcinoma of the Uterine Cervix.
Sang Tag EUM ; Chang Soo PARK ; Sun Young KANG ; Duk Soo BAE ; Je Ho LEE
Korean Journal of Gynecologic Oncology and Colposcopy 1999;10(4):342-349
OBJECTIVE: Flow cytometric deoxyribonucleic acid (DNA) content analysis has been shown to be of prognostic importance in some cancers. In this study, DNA patterns obtained by flow cytometry in patients with cervical cancer have been shown to be related to a prognostic importance in cervical carcinoma. METHODS AND MATERIALS: We retrospectively reviewed 59 cervical cancer patients who admitted to the department of obstetrics and gynecology, Samsung Medical Center firom January 1995 to May 1997. RESULTS: A total of 59 archival paraffin-embedded blocks were proc 42.4 percent were found to be DNA content aneuploid (DNA-A) and 57.6 percent DNA content diploid (DNA-D). The S-phase fraction was significantly increased with stage. The incidences of aneuploid and relative DNA index were not significantly increased with the stage(P=0.280) and age of patients(P=0.088). The results had no significant differences between the squamous cell carcinoma and adenocarcinoma, and no relationship between the groups with keratinizing cell type and nonkeratinizing type(P=0.409). The DNA ploidy patterns were not significantly correlated with metastasis to lymph node(P=0.179), tumor size(P=0.109), invasion depth(P=0.361) and recurrent group(P=0.285). High S-phase fraction had a tendency to correlate with the invasion depth(P=0,011), size(P=0.027), lymph node metastasis(P=0.039) and recurence(P=0.099) of cervical cancer. CONCLUSION: Flow cytometric DNA content analysis is being used more frequently in the management of different malignant tumors. Our study shows that DNA content analysis may not serve as an important biological indicator in determining the prognosis in cervical carcinoma, but High S-phase fraction has been connected with more aggressive tumors.
Adenocarcinoma
;
Aneuploidy
;
Carcinoma, Squamous Cell
;
Cervix Uteri*
;
Diploidy
;
DNA*
;
Female
;
Flow Cytometry
;
Gynecology
;
Humans
;
Incidence
;
Lymph Nodes
;
Neoplasm Metastasis
;
Obstetrics
;
Ploidies
;
Prognosis
;
Retrospective Studies
;
Uterine Cervical Neoplasms
8.Alveolar Soft-Part Sarcoma of the Female Genital Tract.
Ji Young KIM ; Jong Dae WHANG ; Chang Soo PARK ; Duk Soo BAE ; Je Ho LEE
Korean Journal of Obstetrics and Gynecology 1998;41(11):2875-2878
Alveolar soft-part sarcoma of the female genital tract are extremely rare. Fewer than 30 cases have been described in the literature. We experienced a case of alveolar soft-part sarcoma of the female genital tract which was diagnosed by routine light microscopic study using ultrastructural and immunohistochemical stain. We report this case with a brief review of the literature.
Female*
;
Humans
;
Sarcoma, Alveolar Soft Part*
9.The reasonable timing of the adjuvant radiotherapy in the treatment of uterine carcinosarcoma according to the surgical intent: suggestion based on progression patterns.
Jeong Il YU ; Doo Ho CHOI ; Seung Jae HUH ; Won PARK ; Dongryul OH ; Duk Soo BAE
Radiation Oncology Journal 2013;31(2):72-80
PURPOSE: We designed this study to identify and suggest the reasonable timing of adjuvant radiotherapy in the treatment of uterine carcinosarcoma according to the surgical intent and patterns of progression. MATERIALS AND METHODS: We retrospectively analyzed a total of 50 carcinosarcoma patients diagnosed between 1995 and 2010. Among these 50 patients, 32 underwent curative surgery and 13 underwent maximal tumor debulking surgery. The remaining five patients underwent biopsy only. Twenty-six patients received chemotherapy, and 15 patients received adjuvant radiotherapy. RESULTS: The median follow-up period was 17.3 months. Curative resection (p < 0.001) and stage (p < 0.001) were statistically significant factors affecting survival. During follow-up, 30 patients showed progression. Among these, eight patients (16.0%) had loco-regional progression only. The patients who had received adjuvant radiotherapy did not show loco-regional progression, and radiotherapy was a significant negative risk factor for loco-regional progression (p = 0.01). The time to loco-regional progression was much earlier for non-curative than curative resection (range, 0.7 to 7.6 months vs. 7.5 to 39.0 months). CONCLUSION: Adjuvant radiotherapy in the treatment of carcinosarcoma might be related to a low loco-regional progression rate. Radiotherapy should be considered in non-curatively resected patients as soon as possible.
Biopsy
;
Carcinosarcoma
;
Follow-Up Studies
;
Humans
;
Radiotherapy, Adjuvant
;
Retrospective Studies
;
Risk Factors
10.a case of primary adenocarcinoma of fallopian tube.
Kwon Il ROH ; Hae Suk KIM ; Duk Soo BAE ; Chang Jae SHIN ; Jung Gu KIM
Korean Journal of Obstetrics and Gynecology 1991;34(1):144-151
No abstract available.
Adenocarcinoma*
;
Fallopian Tubes*
;
Female