So far today the blood Picture of specific dermatoses such as leprosy, syphilis, skin tubercuIosis, pemphigus and eczema was studied a good many ways. Author has studied the blood picture especially red blood cells, hemoglobin, hematocrit, white blood cells and its differential counts in 217 cases of various skin diseases such as contact. dermatitis, urticaria, chronic eczema, atoPic dermatitis, seborrheic dermatitis, erythema multiforme, erythemanodosum, drug eruption, prurigo, lichen urticatus, exfoliative dermatitis and purpura. At the same time liver function tests were performed in 46 cases including 25 cases of contact dermatitis, 6 cases of chronic eczema, 5 cases of atopic dermatitis, 5 cases of urticaria and 5 cases of exfolistive dermatitis. Afterwards the correlations of those two groups were investigated. Among all mentioned above dermatose except purpura no changes of red blood cells, hemogiobin and hematocrit were observed according to the authors own control of normal values which were obtained in 62 normal healthy adults. Other findings are as follows; 1. In contact dermatitis leucocytes and eosinophils are increased while neutrophils slightIy decreased. 2. Moderate increase of lymphocytes in urticaria. 3. In chronic eczema leucocytes and lymphocytes slightly increased but neutrophils somewhat decreased. 4. In atopic dermatitis leucocytes and eosinophils increased and there was also moderate increase of lyrnphocytes. 5. In seborreheic dermatitis monocytes and basophils were increased but eosinophils were slightly increased. 6. In erythema multiforme monocytes were decreased and leacocytes increased slightly. 7. In erythema nodosum neitrophils increased and lymphocytes and monocytes were decreased. 8. In drug eruption monocytes were decreased. 9. ln Prurigo eosinophils were increased. 10.:ln lichen uiticatus neutrophils were decreased. 11. In exfoliative dermatitis there are marked increase of leucocytes and eosinophils and decrease of neutrophiIs, lymphocytes and basophils. 12. In purpura red b!ood cells, hemoglobin, hematocrit were decreased. The increase of white blood cells in contact dermatitis and exfoliative dermatitis almost paralleled with the extension of their lesions. Marked liver function disturbarces were found in a good many cases cf exfoliativedermatitis while slight degree of liver function disturbances were found in some cases of contact dermatitis and it was found that some cases of chronic eczema, urticaria and atopic dermatitis gave some influence to liver function. The fact of leucocytes increase in exfoliative dermatitis and contact dermatitis seems more or less go parallels with liver function disturbances.
Adult ; Basophils ; Dermatitis ; Dermatitis, Atopic ; Dermatitis, Contact ; Dermatitis, Exfoliative ; Dermatitis, Seborrheic ; Drug Eruptions ; Eczema ; Eosinophils ; Erythema Multiforme ; Erythema Nodosum ; Erythrocytes ; Hematocrit ; Humans ; Leprosy ; Leukocytes ; Lichens ; Liver ; Liver Function Tests ; Lymphocytes ; Monocytes ; Neutrophils ; Pemphigus ; Prurigo ; Purpura ; Reference Values ; Skin Diseases* ; Syphilis, Cutaneous ; Urticaria

Radiologic findings of Total colonic Aganglionosis(T.C.A.) were analized in 15 patients with the results asfollows; 1. Male to female ratio was 8:7. 2. There were six cases of small calibered colon, seven cases of normalcolon and two cases of megacolon. 3. Free reflux of barium into the small bowel was observed in seven cases out ofeight in which retrograde filling was tried. 3. Delayed films (24 hrs or more) were available in eight cases andmost of the barium remaned in bowel in six cases. 5. There were abnormal colonic contractions in three cases,decreased redundancy in five and five cases of irregular, hypertrophic mucosal wall suggesting enterocolitis. 6.Part of ileum were also aganglionic in five cases. There seems to be no pathognomonic barium enema findings inT.C.A. But combination of these findings may suggest the possibility of T.C.A. T.C.A. should be considered indifferential diagnosis of bowel obstruction in infants. Barium enema should be complete and delayed films alwaysbe obtained.
Barium ; Colon ; Diagnosis ; Enema ; Enterocolitis ; Female ; Hirschsprung Disease ; Humans ; Ileum ; Infant ; Male ; Megacolon

No abstract available.
Gait*

A case of lupus vulgaris who has the typical skin lesion on the patella region of the right knee was presented. The patient is 9 years old, the generally healthy male, and is no special finding of chest X-ray but tuberculin test was strong positive. The skin lesion started about 2 years ago as baby's palm sized erythematous patch with apple jelly nodule on the right knee joint region. Diagnosis was made by characteristic of clinical appearance and histulagial finding including other laboratory data. The treatment was done with INAH, PAS, streptomycin and pyridoxine for 3 months. Now,The skin lesion is almost healed and still continue treatment and observation go on.
Child ; Diagnosis ; Humans ; Knee Joint* ; Knee* ; Lupus Vulgaris* ; Male ; Patella* ; Pyridoxine ; Skin ; Streptomycin ; Thorax ; Tuberculin Test

Xeroderma pigmentosum, a rare, genetically determined dermatosis, is often cornplicated by malignant chagnes of various types-most commonly, basal-cell epithelioma, squamous cell epithelioma, less frequently malignant meIanoma, keratoacanthoma, fibrosarcoma, and endothelioma have been reported. In Korea, no case has ever been reported in literature except four cases at a symposium for dermatology, two of them complicated by basal-cell epithelioma, and the others by squamous cell epithelioma. This case reported was complicated by squamous cell epithelioma. As one of the anticancer treatments, especially for skin cancer, Bleomycin is, now, drawing the attention for its high therapeutic index with only few side effects. For this case, we injected Rleomycin 15mg at once, twice a week, for 8 weeks, So total injection was 16 times and 240mg of Bleomycin was given in total. While this amount given for this case was not enough for the complete treatment of squamous cell epithelioma, we got the following results: 1. Clinically, the ulcerated lesion of the cancer on the right ala nasi had shrunken in size with reepithelialization at the margin showing clear surface, and 2. microscopically, the atypical cancer cell masses and individual cell keratinizations had been decreased in size and in number, and less remarkable comparing to those in untreated stage at his first visit to the hospital.
Bleomycin* ; Carcinoma* ; Dermatology ; Fibrosarcoma ; Keratoacanthoma ; Korea ; Skin Diseases ; Skin Neoplasms ; Ulcer ; Xeroderma Pigmentosum

The authors experienced a case of typical pellagra in 45-year old male. He has been a heavy alcoholic history about 30 years duratian. Well-marginated erythematous created scaly patches, hyperpigmentation and fissures developed on both forearms and both ear lobes, both periorbicular areas, and Casals and klace on the aa0erior neck repeatedly. The skin leaions were aggravated in summers, improving a little in winters from 3 years ago. The psychoneurotic symptoms, neurologic disturbances, and GI troubles accompanied the skin lesions. Diagnosis was made by the characteristic clinical findings. He was treated with nicotinamide and vitamin B complex, and most of symptoms improved much. Authors reported the case and reviewed the literatures.
Alcoholics ; Diagnosis ; Ear ; Forearm ; Humans ; Hyperpigmentation ; Male ; Middle Aged ; Neck ; Neurologic Manifestations ; Niacinamide ; Pellagra* ; Skin ; Vitamin B Complex

With development of immunochemical methods for anlysis of serum proteins, quantitative determination of serum immunoglobulin levels and purification of them have been made possible in recent years. There are numerous reports about immunoglobulin levels in various diseases. A search of the literature reveals very few reports of quantitative immunoglobulin determinations in allergic dermatoses. The present study was conducted to find quantitative changes of serum immunoglobulins in a few allergic dermatoses. To quantify the IgG, IgA and IgM, one hundred and two sera were analysed form 30 normal control group, 30 contact dermatitis patients, 12 stopic dermatitis patients and 30 urticaria patients by modified Oudin's capillary tube method. The results are as follows. 1.In contact dermatitis the IgG was significantly increased to compare with control group(p<0.01) 2.In atopic dermatitis the IgA was significantly increased to compare with control group(p<0.01) 3.In urticaria the IgG was increased (p<0.05) 4.The IgM has no differences between allergic dermatoses and control group.
Blood Proteins ; Capillaries ; Dermatitis ; Dermatitis, Atopic ; Dermatitis, Contact ; Humans ; Immunoglobulin A ; Immunoglobulin G ; Immunoglobulin M ; Immunoglobulins ; Skin Diseases* ; Urticaria

Two cases of leukemia cutis associated with leukemia has been demonstrated. Case 1: 24 year old man had been fever, arthralgia and leproma like hard infiltrated nodular lesion with hemorrhagic macules was noted on face and upper arms and trunk, Monocytic Jeukemia has been presented. In peripheral blood and bone marrow finding, immature blood cells was counted in about 80%, Case 2: 64 yearold woman, had been erythematous papule with itching on lower extremities and coin ized ulcerated nodule was noted on lumbosacral region. Myeloid leukemia has been presented. In peripheral blood and bone marrow finding, immature blood cells was counted in about 7.2%. Diagnosis of cutaneous lesions was by clinical apperance and histopathological change. By laboratory examination, monocytic leukemia and myeloid leukemia was revealed in peripheral blood and bone marrow preparation.
Arm ; Arthralgia ; Blood Cells ; Bone Marrow ; Diagnosis ; Female ; Fever ; Humans ; Leukemia* ; Leukemia, Myeloid ; Lower Extremity ; Lumbosacral Region ; Numismatics ; Pruritus ; Ulcer ; Young Adult

The proteins, especially the 19S globulin (IgM) and 7S globulin (IgA) in the CO2 snow-induced blister fluids of 10 male healty volunteers were analyzed immunoelectrophoretically. The fnllawing results were obtained. 1) Compared with autologous serum, all blister fluids tested lacked some protein fraction lines. 2) The 19S globulin (lgM) line was absent in all of the blister fluids except one which was contaminated with blood. 3) The 7S globulin (IgA) line was present in all of the blister fluids when undiluted. In 1 : 2 dilution, however, it was absent, or of trace amount in a few cases.
Blister* ; Humans ; Male ; Volunteers

Several immunosuppressive agents were used to prolong the survival of full-thickries skin homografts in albino rats. The grafts were squares in size of 2.0cm. The results were as follows. 1. The mean survival time of skin homografts in control group was 6.0 days. 2. Total body X-irradiation (500r) to the recipients 24 hours before grafting resulted in prolongation of survival of the grafts. (Mean, 12.5 days) 3. Administration of Imuran(azathioprine) to the recipients in a does of 5mg/kg/day for 7 days. before grafting resulted in prolongation of survival of the grafts. (Mean, 9. 6 days) 4. Spleneetomized homografted rats showed no prolongation of survival of the grafts. (Mean, 6.1days) 5. Administration of prednisolone to the recipients in a does of 2mg/kg/day for 7 days before grafting resulted in no prolongation of survival of the grafts. (Mean, 6.3 days) 6. Above results were discussed and compared with those of others.
Allografts* ; Animals ; Azathioprine* ; Immunosuppressive Agents* ; Prednisolone* ; Rats* ; Skin* ; Splenectomy* ; Survival Rate ; Transplants ; Whole-Body Irradiation*