A relationship between preceding acute paralytic poliomyelitis and the later development of motor neuron disease has only occasionally been suggested since it was first postulated by Charcot in 1875. The authors recently experienced a 20-year-old male who was considered to have postpoliomyelitis muscular atrophy. We report this case in view of its rarity and necessity of differential diagnosis from other neuromuscular disorders. Clinical presentation included slowly progressive muscle wasting of left thigh for 4 years, mild weakness of left arm and both thigh, intermittent fasciculation, and previous history of acute paralytic poliomyelitis. Electromyographic findings showed fibrillation potentials, positive sharp waves, fasciculations, giant motor unit potentials and reduced interference patterns. Muscle biopsy revealed scattered small angulated fibers, individual myofiber degeneration and mild inflammatory cell infiltration.
Arm ; Biopsy ; Diagnosis, Differential ; Fasciculation ; Humans ; Male ; Motor Neuron Disease ; Poliomyelitis ; Postpoliomyelitis Syndrome* ; Thigh ; Young Adult

During last 20 years from 1959 to 1978, 75 cases of the congenital pyloric stenosis were admitted to department of pediatrics of Yonsei University College of Medicine, and evaluated clinically. The results obtained are asfollows: 1.Vomiting is usually developed during 2 to 4 weeks of life(38 cases, 50%) and the ratio of male to female was 6.5:1. 2. The incidence among siblings were 37 cases in 1st born, 20 cases in 2nds and 9 cases in 3rds. 3. The duration from onset to admission showed a eak incidence between one to two weeks(41 cases among 75 cases) 4. In the symptoms and physical findings; Non-bile stained vomiting was developed in all of the cases, abdominal masses palpated in 67 cases(90%), and visible peristaltic waves were observed in 25 cases(33%). 5. Metabolic alkalosis was developed in 25 cases (33%), serum Na concentration was ranged between 130~150mEq/l in 59 cases and serum K concentration between 3~5mEq/l in 65 cases. 6. 70 cases received surgical treatment. 69 cases were improved, and one case was expired due to aspiration pneumonia. 4 cases were improved with medical treatment including anticholinergics.
Alkalosis ; Cholinergic Antagonists ; Female ; Humans ; Incidence ; Male ; Pediatrics ; Pneumonia, Aspiration ; Pyloric Stenosis ; Pyloric Stenosis, Hypertrophic* ; Siblings ; Vomiting

Cutis marmorata telangiectatica congenita(CMTC) is a rare congenital cutaneous vascular anomaly. The major skin findings are persistent, fixed cutis marmorata, telangiectasia, and phlebectasia. In approximately 50 % of patients, the disorder tends to be associated with various con-genital anomalies. We describe in this report a 4-month-old male infant with CMTC. The patient had red or violet marbled patches, telangiectases, and atrophy on the right arm present at birth. During the follow up period of 12 months, there was no change in the cutis marmorata pattern and telangiectases, whereas the atrophy has been less prominent than at the initial visit.
Arm ; Atrophy ; Follow-Up Studies ; Humans ; Infant ; Male ; Parturition ; Skin ; Telangiectasis ; Viola

No abstract available.
Animals ; Mucous Membrane* ; Rats*

Scurvy is a manifestation of deficiency of vitamin C, which was characterized by follicular hyperkeratosis, hemorrhagic manifestation, fatigue, muscular ache and pains, swollen jonts, swollen bleeding gums, and peripheral edema. Rescently we experienced a cases of scurvy in 13 month old boy who had been nourished by artificial feedings with ricegruel without additional vitamin C. Rentgenographic findings of bone revealed rosaries in all costochondral junctions and typical scorvutic changes in both femur. Scury is very rare disease in korea now. A brief review of literature was done.
Ascorbic Acid ; Edema ; Femur ; Gingiva ; Hemorrhage ; Humans ; Infant ; Korea ; Male ; Muscle Fatigue ; Rare Diseases ; Scurvy*

We evaluated the role of antimicrobials in the treatment of chronic maxillary sinusitis in children with chronic cough. At the first visit 216 of 276 cases with chronic cough had radiologically abnormal maxillary sinuses (78.3%). By the Waters x-rays around 50 cases each were assigned randomly to four groups; among them, 48 cases were given an amoxicillin, 51 cases were given trimethoprim-sulfamethoxazole (TMS), 53 cases were given amoxcillin plus TMS and 50 cases were given expectorant plus decongestant (control) group. Thus, 202 children were included for data analysis. Treatment was given for two weeks in each group. The group treated with antimicrobials had a significantly higher cure rate than that of expectorant plus decongestant group (P < 0.001). Most of the patients who had roentgenographic improvement have successfully recovered from the chronic cough and the other cardinal signs of chronic sinusitis.
Adolescent ; Anti-Infective Agents/therapeutic use* ; Child ; Child, Preschool ; Chronic Disease ; Cough/drug therapy* ; Female ; Human ; Male ; Sinusitis/drug therapy*

Endobronchial metastasis from extrapulmonary carcinoma, both clinically and radiologically similar in appearance to a primary lung cancer, is rare. We present a case of endobronchial metastasis from parosteal osteosarcoma. The first abnormality noted on the chest radiography was tramline calcification with branching pattern along the right upper lobe bronchus and intermediate bronchus. This lesion progressed into a solid calcified nodule which increased in size. Another lesion with same pattern was also observed in the left lower lung zone.
Bronchi ; Lung ; Lung Neoplasms ; Neoplasm Metastasis ; Osteosarcoma* ; Radiography ; Thorax

We treated a rare case of TO that presented with recurrent massive hemoptysis that resulted in total obstruction of the bronchus intermedius by very large blood clots. Bronchoscopic intervention resulted in a full recovery from the atelectasis. However, there are no guidelines for preventing recurrence of the hemoptysis or disease progression. Conservative and expectant management are used to treat these patients and most do well.
Bronchi ; Disease Progression ; Hemoptysis ; Humans ; Pulmonary Atelectasis ; Recurrence

PURPOSE: To compare the accuracy of lateral radiography of the spine with that of morphometric X-rayabsorptiometry(MXA) in vertebral morphometry, and to evaluate normal vertebral morphometry using MXA in Koreanwomen. MATERIALS AND METHODS: A spine phantom was constructed using copper pipe. Its anterior and posteriorheights were measured directly, with lateral radiographs and with MXA, and the values thus obtained were compared.Inter -and intra -observer variations were evaluated by three radiologists. The vertebral morphometry of 30 youngwomen volunteers were imaged using thoracic and lumbar lateral radiographs and MXA, and analysis included themeasurement of anterior and posterior heights from T4 to L4. We also obtained the vertebral morphometry of 200normal Korean women who underwent MXA between March 1995 and February 1996, though those with osteoporosis andother spinal lesions were excluded from this study. Thoracolumbar vertebral indexes were statistically correlatedwith age, height and bone mineral. RESULTS: There were no statistically significant differences in the heights ofspine phantom measured by MXA compared with actual size (mean difference=0.28mm). Simple radiographs weremagnified by 23.7% at a phantom-table distance of 15cm, and distortion ranged from 0.5% to 22.5%, depending onphantom level and phantom-table distance. In the study of volunteers, the magnification rate between a simpleradiograph and MXA was about 26.6%. Anterior height increased progressively from the thoracic to the lumbar spine,though posterior height peaked at L2, and L4 was less than anterior height. In Korean women, indices of vertebralmorphometry decreased significantly with aging, with the most prominent decrease occurring during the seventhdecade. The mineral density of spinal bone decreased markedly after the sixth decade. CONCLUSION: Radiographsshowed more magnification and distortion than did MXA, though between morphometric X-ray absorptiometry (MXA) andactual size, there was no significant difference. The vertebral morphometric indices of Korean women and referredbone mineral density may provide useful data for determining and evaluating follow-up changes in spinalmorphology.
Absorptiometry, Photon ; Aging ; Copper ; Female ; Humans ; Osteoporosis ; Radiography ; Spine* ; Volunteers

BACKGROUND: Clinically apparent thyroid nodule is a very common disease in adults. Patients are often treated with thyroxine in order to reduce the size of the nodule, but the efficacy of thyroxine-suppressive therapy with thyroxine remains uncertain. We investigated the efficacy of thyroxine-suppressive therapy and the hormonal characteristics during thyroxine therapy to find out whether such measurement could be used to determine the effectiveness of this therapy in patients with benign solitary thyroid nodule proved by aspiration biopsy. METHODS: In this study, 54 patients were randomly assigned to receive L-thyroxine (Group I, n=24) or placebo (GroupII, n=30) for 1 year. High resolution ultrasonography (10MHz) was used to measure the size of the nodules at six month intervals. Thyroid hormones and thyroglobulin assay and FNA (fine needle aspiration) was done at the same time. The dose of thyroxine was 200ug/day. Patients were followed at 6 month intervals. RESULTS: The results were as follows: 1) 13 (54.1%) out of 24 Group I patients after adequate TSH suppression had a statistically significant reduction of nodule size and before-to-after nodule volume ratios were significantly different between the Group I and Group II patients. 2) In the responders among Group I patients, the before-to-after therapy ratio of the nodule volume was not related to the pretreatment nodule size, thyroid hormones and thyroglobulin levels. CONCLUSION: Thus we concluded that an adequate suppressive dose of L-thyroxine significantly altered the volume of the benign solitary thyroid nodules 12 months later.
Adult ; Biopsy, Needle ; Humans ; Needles ; Thyroglobulin ; Thyroid Gland* ; Thyroid Hormones ; Thyroid Nodule* ; Thyroxine* ; Ultrasonography