No abstract available.
Syringoma

No abstract available.

We report a case of pigmented spindle cell nevus occurred in a 4-year-old girl. The lesion was well-demarcated, 2.5 x 3mm sized black macule on the left thenar area. The histopathologic findings of excisional biopsy specimen revealed the prociferation of uniform spindle-shaped pigmented melanocytes at the dermoepidermal junction and sharply definded lateral margins.
Biopsy ; Child, Preschool ; Female ; Humans ; Melanocytes ; Nevus, Spindle Cell*

Two typical cases of epithelioid sarcoma were examined by immunohistochemical stain using antibodies to epithelial membrane antigen, carcinoembryonic antigen, vimentin and cytokeratin. Both cases showed positive reactivity for the four kinds of antibodies. These results point to the fact that epithelioid sarcoma simultaneously expresses epithelial markers and characteristic mesenchymal phenotypes. Epithelioid sarcoma appears to be a tumor derived from a multipotential mesenchymal cell with multidirectional differentiation.
Antibodies ; Carcinoembryonic Antigen ; Keratins ; Mucin-1 ; Phenotype ; Sarcoma* ; Vimentin

The congenital ball-and-socket ankle joint is a rare condition and is associated with congenital shortening of the lower extrimity and various skeletal abnormalities of the foot. This disease entity was reported in the German literature by Politzer in 1931 and in the English literature by Lamb in 1958. Several series have been reported since, suggesting that the condition may not be as rare as generally thought. This case is, to our knowledge, the first reported in this country.
Ankle Joint ; Ankle ; Foot

Annular erythema associated with lupus erythematosus/ Sjogrens syndrome has recently been described in Orientals. We present a patient with recurrent annular erythema who partially demonstrated features of lupus erythematosus. A 32-year-old man was referred to us for recurrent annular erythema. Laboratory findings revealed mild leukopenia and the presence of antinuclear antibodies at a titer of 320 with a finely speckled pattern on Hep-2 substrates. Anti-Ro/La antibodies were also detected. A skin biopsy specimen revealed the findings of perivascular and periappendageal lymphocytic infiltration without prominent hydropic degeneration of the basal layer. Skin lesions subsided with hydroxychloroquine (400-200mg/day).
Adult ; Antibodies ; Antibodies, Antinuclear ; Biopsy ; Erythema* ; Humans ; Hydroxychloroquine ; Leukopenia ; Sjogren's Syndrome ; Skin

A 65-year-old female patient visited our clinic complaining of multiple skin lesions since one year ago. There were yellowish to brownish colored, bean to walnut-sized nodules on both lower extremities. Dylon stain with polarizing microscopy, immunohistochemical stain to amyloid P and immunoglobuhn-kappa chain showed positive reactivities but keratin stain was negative. According to histopathologic and immunohistochemical findings, she was diagnosed as nodular amyloidosis.
Aged ; Amyloid ; Amyloidosis* ; Female ; Humans ; Lower Extremity ; Microscopy ; Skin

Condyloma acuminatum is a common viral disease which is transmitted by sexual intercourse. We experienced a case of condyloma acuminatum occurring in a patient of systemic lupus erythematosus who has been treated with various immunosuppressive agents for 10 years. This condylorna acuminatum was unusual in that it was very rapidly growing, recurrent and reluctant to various treatrnents. We investigated the type of human papillomavirus by Southern blot hybridization and schieved partial improvement by bleomycin intralesional injection together with 5-FU topical application.
Bleomycin ; Blotting, Southern ; Coitus ; Fluorouracil ; Humans ; Immunosuppressive Agents ; Injections, Intralesional ; Lupus Erythematosus, Systemic ; Virus Diseases

BACKGROUND: Opioids are frequently used to relieve pain or to induce sedation during monitored anesthesia care and regional anesthesia. Infusion rates for alfentanil range from 0.25-0.72 microgram/kg/min. This study was performed to define the optimal range of blood concentration of alfentanil to produce a conscious sedation without significant vital sign changes and side effects in spinal anesthesia patients. METHODS: One hundred patients were administered spinal anesthesia with 0.5% hyperbaric bupivacaine 12-18 mg and then a target controlled infusion (TCI) of alfentanil using a syringe pump equiped with a stelpump program. The target concentrations of alfentanil were 20 ng/ml (n = 20, group A20), 25 ng/ml (n = 20, group A25), 30 ng/ml (n = 20, group A30), 35 ng/ml (n = 20, group A35) and 40 ng/ml (n = 20, group A40). Sedation scale, bispectral index (BIS), systolic and diastolic blood pressure, heart rate, SpO2, and anxiety score were checked during the operation and postoperatively one hour later in the recovery room. RESULTS: The sedation scale was significantly higher in groups A30, A35, and A40 than in the other two groups (P < 0.05), but there were no significant difference in BIS among the groups. Mean infusion rates of alfentanil were 0.27-0.46 microgram/kg/min. Time from end of alfentanil infusion to response to a verbal command was significant delayed in groups A30, A35, and A40 than in the other two groups. Recall of operative procedure occurred in 50 65%. Intraoperative hypotension, bradycardia, and respiratory depression occurred more frequently in groups A35, and A40 than in the other three groups (P < 0.05). Incidences of postoperative nausea and vomiting were significantly higher in groups A35, and A40 than in the other three groups (P < 0.05). Heart rate and systolic and diastolic pressures were more significantly lowered during the operation in groups A35, and A40 than in the other three groups (P < 0.05). CONCLUSIONS: Alfentanil has an effective sedation effect at 40% of the analgesic dosage during spinal anesthesia. But, incidences of side effects, like hypotension, bradycardia, and nausea and vomiting increased with alfentanil target concentrations. TCI of alfentanil at 30 ng/ml produces effective sedation, antianxiety effect, and fewer side effects during spinal anesthesia.
Alfentanil* ; Analgesics, Opioid ; Anesthesia ; Anesthesia, Conduction ; Anesthesia, Spinal ; Anti-Anxiety Agents ; Anxiety ; Blood Pressure ; Bradycardia ; Bupivacaine ; Conscious Sedation* ; Heart Rate ; Humans ; Hypotension ; Incidence ; Nausea ; Postoperative Nausea and Vomiting ; Recovery Room ; Respiratory Insufficiency ; Surgical Procedures, Operative ; Syringes ; Vital Signs ; Vomiting

Mullerian agenesis or dysgenesis, rare developmental anomaly presenting as primary amenorrhea, is characterized by absence of vagina and absence or rudimentary development of the uterus. Anatomic anomalies of the axial skeleton and kindney often accompany this psychologically devatating condition. There are various methods of surgical treatment for congenital absence of the vagina. The six cases reviewed in this paper were all treated with McIndoe technique. All of 6 women experienced satisfactory sexual activity and were satisfied with vaginal depth following vaginal creation using a split thickness skin graft technique. Despite the existence of several alternative methods, the McIndoe technique is a relatively simple and highly successful procedure and hence is still prefered by many surgeons.
Amenorrhea ; Female ; Humans ; Sexual Behavior ; Skeleton ; Skin ; Transplants ; Uterus ; Vagina*