1.A Case of Gastritis Cystica Polyposa, Presenting as a Submucosal Tumor - like Lesion.
Sin Ae KIM ; Young Duk CHO ; Moon Sang LEE ; Jin Hong KIM ; Sung Won CHO ; Chan Sup SHIM
Korean Journal of Gastrointestinal Endoscopy 1990;10(2):337-340
Gastritis cystica polyposa (GCP) is a lesion characterized by all the histological features described for hyperplastic polyps, And there is s marked proliferation of muscular elements and entrapment of numerous epithelial cysts. These lesions have been described at gastroenterostomy stomas, at peptic ulcer edges, and in association with carcinoma. It is rare that GCP presenting as a submucosal tumar-like lesion develops in the absence of above mentioned associated conditions. We had experienced a 69 year-old man with GCP. Barium X-ray and endoacopic findings showed submucosal tumor in antrum, and endoscopic ultrasonograpic findings showed markedly thickened mucosal layer with scattered hypoechoeic areas and the submucosal layer well preserved. GCP was confirmed by histological examination of resected stomach.
Aged
;
Barium
;
Gastritis*
;
Gastroenterostomy
;
Humans
;
Peptic Ulcer
;
Polyps
;
Stomach
2.Partial remission with transarterial embolization in a case of metastatic adrenal cortical carcinoma.
Moon Soo KOH ; Myung Shik LEE ; Seong Woon HONG ; Duk LIM
Journal of Korean Medical Science 1991;6(2):173-176
A case of metastatic adrenal cortical carcinoma in which partial remission was achieved with transarterial embolization is presented as probably the first reported case in the literature to date. A 29-year-old woman was admitted because of adrenal cortical carcinoma which had not responded to mitotane. A left adrenalectomy with segmentectomy of the involved liver had been done previously. Abdominal computerized tomography demonstrated multiple large metastatic tumors in the liver. Transarterial embolization with Gelfoam and 20 mCi of 131I-labeled lipiodol was performed and resulted in a decrease in tumor size and biochemical parameters. Transarterial embolization can be one of the therapeutic modalities for metastatic adrenal cortical carcinomas.
Adrenal Cortex Neoplasms/metabolism/*therapy
;
Adult
;
*Embolization, Therapeutic
;
Female
;
Gelatin Sponge, Absorbable
;
Hepatic Artery
;
Humans
;
Hydrocortisone/metabolism
;
Iodine Radioisotopes
;
Iodized Oil
;
Liver Neoplasms/metabolism/*secondary/*therapy
3.Clinical Studies on Neonatal Hepatitis.
Hong Kyu LEE ; Moon Hee LEE ; Dong Gwan HAN ; Duk Jin YUN
Journal of the Korean Pediatric Society 1978;21(5):389-395
43 cases of neonatal hepatitis were clinicallt evaluated, who were admitted to the pediatric department of Severance hospital furing period from April, 1956 to Februart, 1976. The following results were obtained. There was little difference in sex incidence, and most of them were admitted at the age of 1 month to 3 months after birth. Clinical symptoms and signs on admission were jaundice(95%), hepatomegaly(95%), splenom-egaly(41%), fever(41%), and cough(20%). Clay-colored stool was found in 34 cases(79%), and jaundice was found within 6 weeks after birth in most patients. In laboratory studies, total bilirubin, SGOT, SGPT, and Al. phosphatase were all elevated, and return to normal level at 5 weeks after admission. For the precise diagnosis, needle biopsy of the liver was done in 18 cases, among which 14cases showed multinucleated giant cells in specimen, but in 4 cases, giant cells were not observed, and only intrabepatic cholestasis was seen. As complication, bronchopneumonia(9 cases), sepsis(6 cases), rickets(3 cases), and bleeding(4 cases) developed, but which did not influence the prognosis. Most patients were recovered completely, but 6 patients died during admission and 7 patients were discharged in a hopeless condition.
Alanine Transaminase
;
Aspartate Aminotransferases
;
Bilirubin
;
Biopsy, Needle
;
Cholestasis
;
Diagnosis
;
Giant Cells
;
Hepatitis*
;
Humans
;
Incidence
;
Jaundice
;
Liver
;
Parturition
;
Prognosis
4.functional MRI of Language Area.
Jae Wook RYOO ; Dong Gyu NA ; Hong Sik BYUN ; Duk Woo RO ; Jae Min CHO ; Chan Hong MOON ; Duk Lyul NA ; Kee Hyun CHANG
Journal of the Korean Society of Magnetic Resonance in Medicine 1999;3(1):53-59
PURPOSE: To evaluate the usefulness of functional MR imaging(fMRI) for language mapping and determination of language lateralization. MATERIALS AND METHODS: Functional maps of the language area were obtained during word generation tasks and decision task in ten volunteers(7 right handed, 3 left-handed). MR examination were performed at 1.5T scanner with EPI BOLD technique. Each task consisted of three resting periods and two activation periods with each period of 30 seconds. Total acquisition time was 162sec. SPM program was used for the postprocessing of images. Statistical comparisons were performed by using t-statistics on a pixel-by-pixel basis after global normalization by ANCOVA. Activation areas were topographically analyzed(p<0.001) and activated pixels in each hemisphere were compared quantitatively by lateralization index. RESULTS: Significant activation signals were demonstrated in 9 of 10 volunteers. Activation signals were found in the premotor and motor cortices, the inferior frontal, inferior parietal, and mid-temporal lobes during stimulation tasks. In the right handed seven volunteers, activation of language areas was lateralized to the left side. Verb generation task produced stronger activation in the language areas and higher value of lateralization index than noun generation task or decision task. CONCLUSION: fMRI could be a useful non-invasive method for language mapping and determination of language dominance.
Brain
;
Hand
;
Magnetic Resonance Imaging*
;
Rabeprazole
;
Volunteers
5.Prognostic Value of Elactrophysiologic Tests in Bell's Palsy.
Duk Hong MOON ; Eun Hi SA ; Young Jin YUN ; Dong Jo LEE ; Seong Uk HONG
Journal of the Korean Neurological Association 1996;14(3):781-788
Bell's palsy is a relatively common, unilateral facial paralysis of unknown etiology. The purpose of this study was to evaluate the prognostic value of several electrophysiologic tests in Bell's palsy. Blink reflex (BR), side-to-side compound muscle action potential (CMAP) amplitude comparison, and side-to-side nerve excitability test (NET) threshold differ once have been studied during the first 2 weeks in 66 patients with Bell's palsy. According to the early response of BR(Rl), the patients were divided into 3 groups: Rl< or = 13ms(17cases) ; Rl>13ms(22cases), and absent BR(27cases). There was a remarkable tendency towards a satisfactory recovery from paralysis if BR occurred during the first 2 weeks from onset(p<0.001). In patients with normal BR, 88.2% had a satisfactory recovery, when the reflex was absent a bad prognosis was given in 59.3% of the patients. According to side-to-side CMAP amplitude comparison, the patients were divided into 2 groups; CMAP amplitude comparison > or = 25% (35cases), and CMAP amplitude comparison <25% (31cases). There was a tendency towards a satisfactory recovery from paralysis if side-to-side CMAP amplitude comparison was more than 25% (p < 0,003). In patients with more than 25% of CMAP amplitude comparison, 82.9% of the patients had a satisfactory recovery, but in patients with less than 25% of CMAP amplitude comparison, 51.6% of the patients had a bad prognosis. According to side-to-side NET threshold difference, the patients were divided into 2 groups, NET threshold difference < or = 3.5mA(43cases), and NET threshold difference >3.5mA (23cases). When the threshold of electrical excitability on both sides differs 3.5mA or more an unsatisfactory recovery has strongly to expected(p<0.001). In patients with less than 3.5mA of NET threshold, 81.4% had a satisfactory recovery, but in patients with more than 3.5mA of NET threshold, 60.9% had a bad prognosis. BR, side-to-side CMAP amplitude comparison, and side-to-side NET threshold difference seem to be useful independent indices for predicting the prognosis an early stage of the paralysis.
Action Potentials
;
Bell Palsy*
;
Blinking
;
Facial Paralysis
;
Humans
;
Paralysis
;
Prognosis
;
Reflex
6.A Case of Hereditary Spastic Ataxia.
Young Jin YUN ; Duk Hong MOON ; Dong Jo LEE ; Seon Chool HWANG ; Seong Uk HONG
Journal of the Korean Neurological Association 1995;13(2):396-400
Hereditary spastic ataxia is a familial neurological disorder which exhibit the features of a progressive combined pyramidal tract and cerebellar deficiency. The main features are progressive gait disturbance, incoordination, nystagmus, visual impairment, hyperreflexia, extensor plantar response, peripheral neuropathy, and pes cavus. A 27-year-old male patient with spastic ataxic gait was evaluated. He showed characteristic features of hereditary spastic ataxia. There were another twelve affected members in four generations of his family which may be inherited by autosomal dominant pattern. One of them is reported with review of the literature on familial spastic ataxia.
Adult
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Ataxia*
;
Family Characteristics
;
Foot Deformities
;
Gait
;
Humans
;
Male
;
Muscle Spasticity*
;
Nervous System Diseases
;
Peripheral Nervous System Diseases
;
Pyramidal Tracts
;
Reflex, Abnormal
;
Reflex, Babinski
;
Vision Disorders
7.A case Report of a Spontaneous cervical Hematomyelia.
Dong Jo LEE ; Young Jin YUN ; Duk Hong MOON ; Eun Hi SA ; Seon Chool HWANG ; Seong Uk HONG
Journal of the Korean Neurological Association 1995;13(2):383-386
The spontaneous hematomyelia is an uncommon event and its predisposing conditions are vascular malformation, syringomyelia, pregnancy and delivery, angioma, hemophilia, anticoagulant therapy, etc. We have recently experienced the patient with spontaneous onset and resolving hematomyelia in the cervical spinal cord. A 30-year-old male patient with non-traumatic spinal shock was evaluated. On MRI, a hematomyelia along cervical spi-nal cord was revealed. A suspicious AV malformation was noticed at C3-4 level. Fol-low-up MRIs showed spontaneous resolution of the hematoma.
Adult
;
Hemangioma
;
Hematoma
;
Hemophilia A
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Pregnancy
;
Shock
;
Spinal Cord
;
Spinal Cord Vascular Diseases*
;
Syringomyelia
;
Vascular Malformations
8.Signal Averaged Electrocardiography Using Holter Tape in Patients without Heart Disease.
Soon Chul BAE ; Seok Jun MOON ; Jae Goo KWON ; Duk Whan JANG ; Chang Won LEE ; Hong Soon LEE ; Soo Woong YOO ; Moo Yong RHEE ; Hak Choong LEE
Korean Circulation Journal 1997;27(1):42-48
BACKGROUND: Ventrlcular tachyarrhythmias are major cause of sudden cardiac death in patients after myocardial infarction and their accurate detection seems to be important in prevention of sudden cardiac death. Clinical findings, treasmill test, holter monitoring and coronary angiography have been used to search for high risk group in sudden cardiac death. Recently electrographysiologic stimulation has been to this, but it is not practical, because of high cost and invasiveness. Signal averaged electrocardiogram(SAECG) may be helpful in prediction of high risk group in sudden cardiac death. So we try to know the values of SAECG in Korean patients without heart disease. RESULTS: 1) The mean value and standard deviation of Time domain analysis is as follows ; fQRS : 106.8+/-12.3ms, RMS : 36.2+/-21.5(micro)V, LAS : 27.2+/-8.1ms. 2) The mean value and standard deviation of Spectral turbulence analysis is a follows ; LSCR : 58.6+/-3.9, ISCM : 95.2+/-0.8, ISCSD : 71.8+/-15.7, SE : 6.9+/-1.8. CONCLUSION: There was no significant difference between male and female. Time domain analysis shows significant differences among each hour but spectral turbulence analysis did not. Spectral turbulence analysis shows high specificity.
Coronary Angiography
;
Death, Sudden, Cardiac
;
Electrocardiography*
;
Electrocardiography, Ambulatory
;
Female
;
Heart Diseases*
;
Heart*
;
Humans
;
Male
;
Myocardial Infarction
;
Sensitivity and Specificity
;
Tachycardia
9.Clinical Studies on Purpura.
Kir Young KIM ; Ki Sup CHUNG ; Hong Kyu LEE ; Hun Young MOON ; Ki Young LEE ; Duk Jin YUN
Journal of the Korean Pediatric Society 1977;20(4):271-278
We observed clinically 150 cases who were admitted with complaing of purpura at the Pediatric Department of Severance Hospital Yonsei University College of Medicine during a period of 9 years from July, 1966 to June, 1975. In 150 cases, leukemia, 33 cases (22.0%), was most common disease, followed by I.T.P., allergic purpura, meningococcemia, aplastic a nemia, sepsis in order aqnd the incidence was 20.0% (30 cases), 19.3% (29 cases), 19.3% (29 cases), 14.0% (21 cases), 4.0% (6 cases) respectively. And we observed 1 case of thrombocytopenic purpura complicated with scarlet fever and primary hypersplenism respectively. The highest incidence was between the age of one and six years, and males were affected more frequently than females. Clinical manifestations were anemia, fever, abdominal pain, vomiting, joint pain in general symptoms and nasal bleeding, melena, gum bleeding in hemorrhagic symptoms. Major symptoms were fever, abdominal pain, anemia, na sal bleeding, melena, gum bleeding in thrombocytopenic purpura, and fever, abdominal pain, vomiting, meningeal irritation signs in non-thrombocytopenic purpura. I the laboratory findings, mean value of platelet count was below 40,000/mm(3) in thrombocytopenic purpura, but 190,000/mm(3) in non-thrombocytopenic purpura. And bleeding time was prolonged above 5 minutes in thrombocytopenic purpura, but was below 1 minute in non-thrombocytopenic purpura.
Abdominal Pain
;
Anemia
;
Arthralgia
;
Bleeding Time
;
Epistaxis
;
Female
;
Fever
;
Gingiva
;
Hemorrhage
;
Humans
;
Hypersplenism
;
Incidence
;
Leukemia
;
Male
;
Melena
;
Platelet Count
;
Purpura*
;
Purpura, Schoenlein-Henoch
;
Purpura, Thrombocytopenic
;
Scarlet Fever
;
Sepsis
;
Vomiting
10.Influenza epidemic in the pediatric patients in Seoul, 1991.
Hyun Mi KIM ; Se Ho OH ; Eun Young CHO ; Ki Soo KIM ; Young Seo PARK ; Hyung Nam MOON ; Chang Yee HONG ; Young Suhn KIM ; Kee Duk PARK
Journal of the Korean Pediatric Society 1993;36(3):379-385
Influenza virus culture was performed in 149 patients with influenza-like illness who were admitted or visited to the Department of Pediatrics, Asan Medical Center from january, 1991 to March, 1991. The results were as follows; 1) Of the 149 patients, influenza virus were isolated in the 15 cases. 15 isolates were characterized by the WHO Collaborating Center for influenza: 7 cases were very similar to influenza A/Taiwan/1/86 (H1N1), 1 case was A/Beijing/353/89 (H3N2), 7 cases were B/Guangdon-g/55/89. 2) The age of 15 patients who were confirmed by viral isolation was between 11 months to 10 years. 3) The most common clinical symptoms were fever, vomiting, cough, nausea in deceasing order. 4) Of the total 149 patients, Reye syndrome occured in two patients and myositis occured in one: Influenza A/Taiwan/1/86 (H1N1) virus was isolated in one Reye syndrome patient.
Chungcheongnam-do
;
Cough
;
Fever
;
Humans
;
Influenza, Human*
;
Myositis
;
Nausea
;
Orthomyxoviridae
;
Pediatrics
;
Reye Syndrome
;
Seoul*
;
Vomiting