Purpose: This integrative review aims to identify changes in people with schizophrenia during the COVID-19 pandemic. Methods: An integrative literature review method of Whittemore and Knafl was applied to integrate the studies. The literature search was conducted in six electronic databases using English and Korean search terms. Three researchers independently reviewed the extracted papers and rated their quality based on predetermined inclusion and exclusion criteria. A total of fifteen relevant studies were included. Results: The selected articles were all international papers, and most of them were quantitative studies. The changes observed in people with schizophrenia were summarized as follows: (1) changes in health outcomes: psychosocial (increased levels of depression, stress, anxiety, sleep disturbance, and psychotic-like experience) and physical (reduction in food intake, weight loss, changes in immunerelated clinical values, etc.); (2) changes in treatment and health management: increased hospitalization, decreased ICU hospitalization, and a decrease in outpatient visits and prescription rate. Conclusion This study confirmed the impacts of the COVID-19 pandemic on people with schizophrenia. It is necessary to develop mental health policies and appropriate nursing interventions to help people in preparing for possible future crises.

OBJECTIVE: To investigate the effect of slow walking speed on the gait. METHOD: Twenty healthy young male subjects were recruited. The temporospatial data, kinematic and kinetic data in sagittal plane at two different walking speed (2 km/hr, 4 km/hr) were obtained through three dimensional analyzer with the force plate, and compared these parameters at slow gait speed to those at normal gait speed. RESULTS: The cadence and step length decreased significantly and double support time increased significantly (p<0.05) at slow speed compared to at normal speed. The most peak angle of hip, knee and ankle joint decreased, maximal ankle dorsiflexion angle in stance phase increased significantly at slow speed compared to at normal speed (p<0.05). The most maximal extension and flexion moment and power in sagittal plane decreased compared to at normal speed (p<0.05). CONCLUSION: The results of this study demonstrate that only slow walking speed without any pathology may change the temporospatial, kinematic and kinetic parameters of gait, and these results may be useful to interpret the data of gait analysis in the disabled persons with slow walking speed.
Ankle ; Ankle Joint ; Disabled Persons ; Gait* ; Hip ; Humans ; Knee ; Male ; Pathology ; Walking*

OBJECTIVE: The aim of this study was to investigate the incidence of intrahemispheric diaschisis in subcortical lesions and relationships between involved structures and intrahemispheric diaschisis using positron emission tomography (PET). METHOD: Thirty stroke patients with unilateral subcortical lesions without cortical structural abnormality were recruited. The findings of [18F]Fluoro-2-Deoxy-D-Glucose PET were interpretated by experienced radiologist. RESULTS: In the lesions around basal ganglia, hypometabolism of ipsilateral whole hemisphere was observed in 8 of 20 patients and ipsilateral parietal, frontal, temporal, occipital lobe was observed in order of incidence. Intrahemispheric diaschisis had a tendency to expand when the centrum semiovale was involved. Crossed cerebellar dia-schisis was observed in 17 of 20 patients. In the lesions around thalamus, hypometabolism of ipsilateral whole hemisphere was observed in 6 of 8 patients, and ipsilateral frontal, temporal, parietal lobe was observed in order of incidence. Intrahemispheric diaschisis had a tendency to expand when the internal capsule was involved. Crossed cerebellar diaschisis was observed in 5 of 8 patients. CONCLUSION: This study shows that intrahemispheric diaschisis was observed in all patients with subcortical lesions without cortical structural abnormality and had a tendency to expand to larger area of the cerebral cortex when the connecting fibers between cortical and subcortical structures were involved.
Basal Ganglia ; Cerebral Cortex ; Humans ; Incidence ; Internal Capsule ; Occipital Lobe ; Parietal Lobe ; Positron-Emission Tomography ; Rabeprazole ; Stroke ; Thalamus