Epidemiological studies of monoclonal B-cell lymphocytosis (MBL) have been conducted in limited geographical regions. Little is known about the prevalence of MBL in Asia. We investigated the prevalence and immunophenotypic characteristics of MBL in Koreans who had idiopathic lymphocytosis (lymphocyte count >4.0×109/L) and were ≥40 years of age. A total of 105 leftover peripheral blood samples met these criteria among those from 73,727 healthy individuals who visited the Health Promotion Center, Samsung Medical Center, Korea, from June 2018 to August 2019. The samples were analyzed using eight-color flow cytometry with the following monoclonal antibodies: CD45, CD5, CD10, CD19, CD20, CD23, and kappa and lambda light chains. The overall prevalence of MBL in the study population was 2.9% (3/105); there was one case of chronic lymphocytic leukemia (CLL)-like MBL (CD5+CD23+), one case of atypical CLL-like MBL (CD5+CD23−), and one case of CD5−MBL with a lambda restriction pattern. This is the first study on the MBL prevalence in an East Asian population, and it reveals a relatively low prevalence of MBL in healthy Korean individuals with lymphocytosis.

PURPOSE: To determine the MR findings of cervical lymphadenopathy which distinguish tuberculouslymphadenitis(TL) from metastatic lymphadenopathy(ML). MATERIALS AND METHODS: We retrospectively analyzed the MRfindings of 14 patients with TL and 19 with ML. Thirty-nine lesions in 14 patients with TL and 80 lesions in 19with ML were classified into three categories: conglomerate lesion (TL, 7; ML, 8); discrete lesion withoutnecrosis (TL, 3; ML, 15); and discrete lesion with necrosis (TL, 29; ML, 57). Between TL and ML, we compared age,sex, bilaterality, multiplicity, associated pulmonary tuberculosis, infiltration of adjacent fat, muscle, skin andsubcutaneous tissue, margin, and signal intensities on T1- and T2-weighted images. In discrete lesion, we alsocompared the minimal to maximal dimension ratio, and in discrete necrotic lesion, the thickness and evenness ofrim enhancement, and the location and extent of necrosis. RESULTS: There were statistically significantdifferences between TL and ML in age(34.7+/-13.1 years; 56.1+/-14.3 years), male to female ratio(3:11; 13:6),bilaterality(1/14; 10/19), multiplicity(5/14; 14/19), and associated active pulmonary tuberculosis(7/14; 1/19). OnT2-weighted images, TL showed predominantly homogeneous (30/39) or high (20/39) signal intensity, similar to thatof cerebrospinal fluid, but the signal inteusity of ML was predominantly heterogeneous(58/80), or lower than orsimilar to that of fat(41/80). Between TL and ML, however, there were no statistically significant differences ininfiltration of adjacent tissue, margin, signal intensity and its heterogeneity on T1-weighted image, minimal tomaximal dimension ratio, thickness and evenness of rim enhancement, or the location and extent of necrosis. CONCLUSION: In cervical lymphadenopathy, the existence of TL rather than ML is suggested by single or unilaterallesion in a young woman, by associated active pulmonary tuberculosis, or by homogeneous high signal intensity onT2-weighted MR images.
Cerebrospinal Fluid ; Female ; Humans ; Lymphatic Diseases* ; Male ; Necrosis ; Neoplasm Metastasis* ; Population Characteristics ; Retrospective Studies ; Skin ; Tuberculosis* ; Tuberculosis, Pulmonary

"The computer-based electronic academy of anatomy as the ideal goal", we made this concept to a reality by establishing ANATOMY forum in a nationwide bulletin board system. The concept of ANATOMY forum was designed at a small group meeting of members in Korean Association of Anatomist on October, 1992. Beginning on October 8, 1993, ANATOMY forum offers bulletins, file transfers and citizen band emulation for the anatomist as well as anyone who wants to join. We are providing library area for file transfer with four different library sections-EDUCATION, RESEARCH, INFORMATION OF ACADEMIC SOCIETY and ANATOMY IN GENERAL. In the bulletins we have two kinds of message area. One includes five message sections for the use of all members, consisting of NOTICE, LIBRARY INFORMATION, FOR MEDICAL PERSONNEL, QUESTION and ANSWER and MISCELLANEOUS NOTEBOOK. The another message area is for the executive use of anatomist, including five sections-EDUCATION, LABORATORY, RESTING PLACE, ACADEMIC SOCIETY and CONFERENCE ROOM. Currently we have 115 useful files in the library section, and more than 4,000 informative messages in the bulletins. The number of members of ANATOMY forum is now over than 1,000 including 48 anatomists of the most medical schools in Korea. The majority of the members are medical personnel and medical students. The ANATOMY forum is a group of people who wants to exchange ideas and informations on medical science and anatomy-related topics.
Anatomists ; Education* ; Group Processes ; Humans ; Korea ; Schools, Medical ; Students, Medical ; Telecommunications*