Objective To observe the effect of thymalfasin on non-operative treatment of cervical cancer.Methods Seventy-eight patients with advanced cervical cancer were divided into two groups according to the digital table,each group in 39 cases.The two groups were treated with concurrent chemoradiotherapy.The observation group was given 1.6 mg of thymalfasin subcutaneously each Monday to Friday.While the control group received no additional treatment.And then the two groups were compared in terms of curative effects,adverse reactions,immune states and cellular immune functions.Results The results showed that the differences of curative effects[there were 23 patients in the control group,as compared with 31 patients in the observation group,achieved a complete response(CR),x2=3.852,P<0.05],adverse reactions(grade Ⅲ or Ⅳ radiation-induced enteritis occurred in 4 patients in the observation group,and 12 patients in the control group,x2=5.032,P<0.05;Grade Ⅲ or Ⅳ leukopenia occurred in 16 patients in the observation group,and 25 patients in the control group,x2=4.165,P<0.05;Grade Ⅲ or Ⅳ nausea,vomit occurred in 6 patients in the observation group,and 14 patients in the control group,x2=4.303,P<0.05),immune states and cellular immune functions between the two groups were significant[the counts of CD+3(t=9.236,P<0.05),CD+4(t=7.445,P<0.05),CD+4/CD+8(t=7.445,P<0.05) and NK(t=9.256,P<0.05)]were significantly higher in the observation group after treatment.Conclusion In the treatment of advanced cervical cancer,concurrent chemoradiotherapy combined with thymalfasin can improve the curative effect,reduce the side effects,improve the quality of life and enhance the immunity.

Objective To understand the current situation of medical postgraduates'!honesty edu-cation, find the weak point and explore new ways of the honesty education. Methods The honesty educa-tion survey questionnaire was designed and conducted to the postgraduates of Grade 2014 in Peking University Health Science Center. The research contents included the basic information of postgraduates, honesty cognition, clean and self-discipline, honesty education, the recommendation of honesty education and the application of honesty education carrier. 1 038 questionnaires of a total of 1 142 questionnaires were recovered and the recovery rate was 90.9%. EPIData3.0 software was used for double entry and database establishment, and SPSS 19.0 software for statistical treatment. Results 82.3% (854) of the postgraduates recognized the work of clean government, but only 62.1% (644) of the postgraduates concerned about it. 78.3% (813) of the postgraduates expressed hatred for the dishonest behavior and hoped to eliminate it. 77.6%(806) postgraduates often paid attention to honest education content which was pushed by the new media. 16.5% (171) postgraduates thought that the new media was very important to the honest cognition. Conclusions We should pay more attention to medical postgraduates'!honesty education, find its weak points according to the investigation and make full use of the network and new media. And at the same time we should combine the actual environment to establish a hierarchy of honesty education system, and carry out honesty education through total environment which contains the school administrators, instructors/head teachers and tutors.

Our army medical morals was engendered and developed along with our army medical treatment work.This text is tight and tight hold the "a thought","twice important history affairs","two standard points"and "a slogan",tally up developments experience of the Land Revolution,expatiated process and the basically composition of the mode.

Objective To study the effect of laparoscopicassisted radical gastrectomy in advanced gastric cancer.Methods According to the inclusion criteria,164 patients with advanced gastriccancer who treated in the Cancer Institute and Hospital,Chinese Academy of Medical Sciences betweenJanuary and June of 2009 were enrolled into the study.Based on the operation methods,all cases were divided into the experimental group(laparoscopy group,n =79)and the control group(laparotomy group,n =85).Except for the laparoscopicassisted radical gastrectomy,patients received the same treatment in thethe experimental group and control group.Intraoperative indexes,postoperative pathological results and recovery,complications and 5year survival rate were observed and compared between groups.Results Therecovery time of patient's general condition in the experimental group was shorter than that of the controlgroup(P <0.05).The difference of serious postoperative complications rate between the two groups wassignificant(P <0.05).The difference of 5year survival rate between the two groups was not significant(P >0.05).Conclusion Laparoscopicassisted radical gastrectomy is safe and feasible in the treatmentof advanced gastric cancer.This technique could get equal treatment effect as laparotomy and it has obviousadvantage in postoperative recovery.

Objective To evaluate the key points of anesthetic management for retroperitoneoscopic nephrectomy combined with inferior vena cava ( IVC ) tumor thrombectomy. Methods Perioperative clinical data of 3 patients undergoing retroperitoneoscopic nephrectomy combined with IVC tumor thrombectomy from December 2010 to June 2014 were retrospectively analyzed.There were 2 cases of level Ⅰthrombus and 1 case of level Ⅱthrombus.All the patients were given general anesthesia with intubation.Brief inferior vena cava occlusion was performed in the patient with level Ⅱ thrombus. Results The operation was completed smoothly in all the cases without conversions to open surgery. The operating time was 244, 333, and 289 min, respectively. The total IVC control time for level Ⅱ thrombus was 10 min.No intraoperative pulmonary embolism and other severe anesthetic complications occurred. One patient with level ⅠIVC thrombus was extubated and sent back to surgical ward after surgery, and the remaining 2 patients underwent intensive care monitoring overnight and were extubated and discharged to surgical ward on the next day. Conclusions Retroperitoneoscopic nephrectomy and IVC thrombectomy is a brand-new, difficult but feasible procedure. Anesthesiologist should have a full recognition of surgical procedures and make perfect anesthetic plan to ensure close collaboration. Furthermore, circulatory swing during IVC clamping and perioperative severe complications such as pulmonary embolization and massive hemorrhage cannot be neglected.

[Objective]To investigate the capability of synthesis BMP-2-derived peptide on osteogenic induction in bone marrow stem cells(BMSEs),and to evaluate the osteoinductivity of BMP-2-derived peptide in vitro.[Method]After segregating and cultivating four weeks Wistar rats marrow stromal cells in induction group were induced by osteogenasis medium containing 200 gg/ml BMP-2-derived peptide,and in non-inductional group BMSCs were still culture with DMEM medium.Following continue culture for 2~4 weeks,cells film preparation,alkaline phosphatase activity and calcium deposition were measured.Type I collagen(CoM)and osteopontin(OPN)mRNA expression were measured using real-time fluorescent quantitative polymerase chain reaction(FQ-PCR)technique.The capability of synthesis BMP-2-derived peptide on osteogenic induction of BMSCs was investigated.[Result]After inductived with BMP-2-derived peptide.BMSCs cultured survived well greatly changed in cell morphology,and showed a biological and morphologie characteristics similar to those of osteoblasts.The lever of alkaline phosphatase activity and calcium deposition increased.Col-Ⅰand OPN mRNA were expressed at higher level.In non-inductional group no conspicuous osteogenic induction was shown.[Conclusion]BMP-2-derived peptide can induce BMSCs to differentiate into osteoblasts.It has the similar capacity of osteogenic induction as nature BMP-2,so BMP-2-derived peptide is an ideal cell agent for bone tissue engineering,and can be available widely.

Objective:To knock the phospho-sugar mutase gene (psm) out of the genome of S. mutans strain UA159 and to construct the mutant will lay a foundation for the study of the function of the psm. Methods:Two upstream and downstream DNA sequences of the psm were selected and cloned respectively into multiple cloning sites I and II of suicide plasmid pFW5 to construct the recombinant plasmid which was confirmed by enzyme digesting and sequencing. The recombinant plasmid was transformed into S. mutans UA159 by natural transformation and antibiotic was used to screen the positive transformants. According to the principle of homologous recombination, allelic exchange between the recombinant plasmid and S. mutans UA159 was achieved. Results:By PCR analysis and sequencing, it was confirmed that the psm of S. mutans UA159 was substituted for resistant gene of spectinomycin. Conclusion: The psm-negative mutants of S. mutans UA159 is successfully constructed.

Objective According to the characteristics of digital medicine and demand of digitized management in hospital, we establish a storage system which is cheap, highly expansible, and reliable. Methods The multi personal computer storage system (MPCSS) was constructed by assembling the hardwares and softwares. The image data were archived from major server to storage PC by using NEUSOFT PACS archiving manage system and backuped on storage PC. We simulated the situation that the data on storage PC was lost and restored the data. We also expanded the storage system to enlarge its capacity. Results Average transfer rate from MPCSS was 27 7 Mbit/s (1 byte=8 bit); average cost for this system was 74 RMB/G; six cases in the 187 repeated reading of 100 patients failed. MPCSS can store backup and restore the image data, and can expand the storage size. Conclusion MPCSS is very cheap compared with other high capacity systems or devices. It is feasible and suitable for digital image storage.

Objective To solve the new problems for quality assurance of PACS which imported by the use of PACS.Methods The medical imaging quality control system used between imaging modality and image acquisition gateway was designed.Results The medical imaging quality control system could partially solve the problem for quality assurance of PACS.Conclusion With the use of medical image quality control system,wrong or low quality image can be found and modified earlier.Therefore,the veracity of medical information and medical image of PACS can be improved farther.

Objective To develop a remover of formaldehyde in indoor air. Methods Activated carbon was used as the raw materials, potassium hydroxide as the activator. The activated carbon was modified through activation and impregnation. The influence factors for the formaldehyde adsorption property of activated carbons were evaluated, such as the size, activation temperature, activation time and impregnation time. Results The optimum technics conditions for developing the formaldehyde remover and the optimum conditions to absorb formaldehyde were confirmed. The mass adsorption capacity of the adsorbent was 49.6%, the BET surface area was about 1 591 m2/g and the total pore volume was 1.01 cm3/g. Conclusion The mass adsorption capacity of formaldehyde and the BET surface area of the modified activated carbon in the present paper are better than those of unmodified activated carbon.