1.Clinical significance of combined detection of serum pre-S1,pre-S2 antigen and HBeAg for diagnosis of HBV infection
International Journal of Laboratory Medicine 2014;(9):1112-1113
Objective To investigate the clinical significance of combned detection of serum pre-S1 ,pre-S2 antigen and hepatitis B virus(HBV) e antigen(HBeAg) for diagnosis of HBV infection .Methods Enzyme-linked immunosorbent assay(ELISA) was employed to detect the serum pre-S1 ,pre-S2 antigen and HBeAg of 450 patients with chronic hepatitis B and real-time fluorescent quantitative polymerase chain reaction (FQ-PCR) was used to detect their HBV DNA .Results In patients with different HBV DNA levels ,serum pre-S1 ,pre-S2 antigen and HBeAg showed different expression ,the higher the load ,the higher the expression (P<0 .05) .Pre-S1 ,pre-S2 antigen and HBeAg were all correlated with HBV DNA (P<0 .05) and the descending order of rele-vance were HBeAg ,pre-S1 and pre-S2 antigen .Combied detection of the three indicators showed the highest correlation with HBV DNA .The positive proportion of HBV DNA of patients with the three indicators positive was markedly higher than those in pa-tients with single or two indicators positive (P<0 .05) .Conclusion Combind detection of serum pre-S1 ,pre-S2 antigen and HBeAg may reflect well on HBV replication .
2.Influence of atorvastatin on C-reactive protein level and clinical prognosis for chronic cardiac insufficiency combined with paroxysmal atrial fibrillation patients
Chinese Journal of Postgraduates of Medicine 2012;35(28):21-23
ObjectiveTo investigate the influence of atorvastatin on C-reactive protein (CRP) level and clinical prognosis for chronic cardiac insufficiency combined with paroxysmal atrial fibrillation patients.Methods One hundred and eight-six chronic cardiac insufficiency combined with paroxysmal atrial fibrillation patients were divided into observation group(93 cases) and control group (93 cases) by random number table.The control group was given conventional treatment such as cardiotonic and diuretic,while the observation group was given atorvastatin 20 mg one time/night for 1 year on the basis of conventional treatment.Before and after treatment,lipid,left atrial diameter,left ventricular ejection fraction (LVEF),CRP and clinical outcome were compared.Results Lipid levels of the control group were not significantly different before and after treatment(P > 0.05 ).In observation group,the levels of total cholesterol (TC),low density lipoprotein-cholesterol (LDL-C) and highdensity lipoprotein-cholesterol(HDL-C) after treatment were improved compared with those before treatment [ (4.1 ± 0.6) mmol/L vs.(4.8 ± 0.6) mmol/L,(2.7 ±0.3) mmol/L vs. (3.5 ±0.5) mmol/L,(1.0 ±0.1) mmol/L vs. (0.9 ±0.1) mmol/L,P <0.05].After treatment,the levels of TC,LDL-C and HDL-C in observation group were improved compared with those in control group (P< 0.05 ).There was no significant difference in left atrial diameter and LVEF before and after treatment in two groups.The levels of CRP before and 1 month and 6 months after treatment were ( 15.2 ±3.8),(12.1 ±2.7),(9.9 ±2.8) mg/L in observation group,and (15.0 ±3.8),(14.0 ±2.9),(13.7 ±2.8)mg/L in control group,and there were significant differences between two groups 1 month and 6 months after treatment(P < 0.05).The incidences of atrial fibrillation recurrence and conversion for persistent or permanent atrial fibrillation in observation group were significantly lower than those in control group [6.5% (6/93) vs.21.5% (20/93),6.5% (6/93) vs.19.4% ( 18/93 ),P < 0.05 ].ConclusionAtorvastatin can reduce CRP level of chronic cardiac insufficiency combined with paroxysmal atrial fibrillation patients,and reduce and delay recurrence and progress of paroxysmal atrial fibrillation.
3.Application of theory of quality control in nursing of patients with acute cerebrovascular disease undergoing interventional therapy
Chinese Journal of Practical Nursing 2012;28(31):6-8
Objective To investigate the effect of the application of quality control theory in nursing of patients with acute cerebrovascular disease undergoing interventional therapy.Methods 64 cases of patients with acute cerebrovascular disease from November 2009 to October 2011 in our hospital undergoing interventional therapy were chosen as the research object.They were randomly divided into the control group and the observation group with 32 cases in each group.The control group was given routine care,while the observation group was given nursing intervention under the instruction of quality control theory.The hospital stay,complication rates,satisfaction and SAS score,SDS score between the two groups of patients were compared.Results The length of stay,complication rate,satisfaction degree,SAS scores and SDS scores after the intervention in the observation group were significantly better than those of the control group.Conclusions Application of the theory of quality control in nursing of patients with acute cerebrovascular disease has a better effect,demonstrating an evident advantage in reducing complications and improving patients' mental state.
4.The influence of oxiracetam plus mNGF on serum Lp-PLA2 and S100B protein in patients with acute cerebral infarction
Chinese Journal of Primary Medicine and Pharmacy 2013;20(20):3067-3069
Objective To study the influence of oxiracetam plus mouse nerve growth factor(mNGF) on serum lysophosphatidic acid 2(Lp-PLA2) and S 100B protein in patients with acute cerebral infarction.Methods 124 patients with acute cerebral infarction were randomly divided into the observation group (n =62 cases) and the control group(n =62 cases).The patients in the control group were treated through the conventional treatment,while the patients in the observation group were treated by oxiracetam plus mNGF on the basis of conventional therapy.They were treated for 21 days.Serum Lp-PLA2 and S100B were detected.Results The total effective rate of the observation group was 98.4%,which was significantly higher than 90.3% of the control group (x2 =3.96,P < 0.05).Serum LpPLA2 and S100B were decreased in two groups after treatment.Serum Lp-PLA2 and S100B in the observation group were lower than those in the control group(t =20.9091,3.7273,all P < 0.05).Conclusion Oxiracetam plus mNGF can decrease serum Lp-PLA2 and mNGF in patients with acute cerebral infarction.
5.On how to strengthen the construction and management of the students communites in institution of higher learning
Journal of Chongqing Medical University 2000;25(z1):143-144
In the planned economic system, the old ways of management of college students domitories have existed for tens of years. But there are some problems which hamper the training of creative and high-quality talents. After the socialization of university rear service, it is necessary to strengthen the management of students community, speed up its construction, improve the quality of campus culture and provide good services. This will be probed in the article.
6.Comparison of reproductive outcome of different treatment for tubal pregnancy
Chinese Journal of Primary Medicine and Pharmacy 2011;18(10):1327-1328
Objective To investigate the choice of treatment of tubal pregnancy.Methods 128 patients with tubal pregnancy were randomly divided into 43 patients of drug group,42 cases of laparoscopy group,43 cases laparotomy group.The differences of pregnancy status,time to pregnancy,tubal smooth the situation,length of stay,discharge of blood β-HCG were compared.Results Lapamscopic surgery therapy whose intrauterine pregnancy rate reached 80.9%,one year intrauterine pregnancy rate was up to 66.7%,tubal flow rate was 78.6%,and the pregnancy and discharge time was significantly shorter,and the level of β-HCG decresaed when they would go out hospital.Conclusion Laparoscopic surgery therapy had small trauma,better pregnancy rate,low ectopic pregnancy rate,better tubal patency rate,and it could improve fertility,and make discharging quickly,and was an effective treatment for patients with tubal pregnancy.
7.Etiological factor analysis of 73 pericardial effusion patients
Chinese Journal of Primary Medicine and Pharmacy 2011;18(15):2070-2071
ObjectiveTo find out the etiological factor characteristics and age composition of pericardial effusion,to improve clinical diagnosis and treatment,reduce the misdiagnosis rate. Methods73 pericardial effusion patients in our department were admitted by age into youth group, middle age group and elderly group, and the etiological factor characteristics and age composition of pericardial effusion were analyzed respectively. ResultsThe main pathogenic factors of 73 pericardial effusion patients were cancer, heart failure, tuberculosis, non-specific pericarditis, nontuberculous bacterial infections, as well as renal failure, pulmonary infection, trauma, myocarditis, acute myocardial infarction, collagen disease, hypothyroidism. There was statistically significant of etiological factors on the three groups (P < 0.01 ). ConclusionPathogenic factors of pericardial effusion were affected by many factors, and the significant difference in age composition should be well focused in clinical practice.
8.The risk factors of progressive cerebral infraction
Chinese Journal of Primary Medicine and Pharmacy 2012;19(3):323-324
Objective To explore the risk factors of progressive cerebral infraction.Methods 112 cases with progressive cerebral infarction and 112 cases of acute cerebral infarction were selected.Patients were observed and recorded blood pressure,temperature,WBC,cholesterol,GLU and fibrinogen.Results The differences between blood pressure,temperature,WBC,cholesterol,GLU,fibrinogen and artery stenosis were statistically significant.Conclusion Infections,systolic blood pressure decreased,hyperglycemia,hyperlipidemia,and large artery stenosis were related to progressive cerebral infarction.
9.Curative effect of endoscopic sinus surgery on treatment of non-invasive fungal maxillary sinusitis
Chinese Journal of Primary Medicine and Pharmacy 2009;16(4):613-614
Objective To explore the clinical efficacy of endoscopic sinus surgery on the treatment of non-invasive fangal the maxillary sinusitis. Methods 21 patients with non-invasive fungal maxillary sinusitis patients were given endoscopic sinus surgery. Completely remove of the nasal cavity and sinus disease, fully open, washing si-nusos and give nasal endoscopy on a regular fine. Results Follow-up of 6 months to 4 years,18 cases of cure,1 case of loss of information. 2 case of relapse. Cases of recurrence were cured by endoscopic sinus dressing. Conclusion Endoseopie sinus surgery is an effective measure on trentment of non-invasive fungal maxillary sinuses.
10.Determination of Rhodium by Inductively Coupled Plasma Atomic Emission Spectrometry With Chemical Vapour Generation Sample Introduction Technique
Chinese Journal of Analytical Chemistry 2010;38(3):421-424
An inductively coupled plasma atomic emission spectrometry(ICP-AES) combined with a boron hydride vapour generation device was used for the determination of rhodium in waste catalyst. When the flow rate of sample and sodium borohydride solution was 2 mL/min, waste rate was 6 mL/min, the optimum conditions were as follows: 0.4 L/min of carrier rate, 1.0 mol/L of acidity of nitric acid for vapor generation and concentration of sodium borohydride 1.2(m/V). The study showed that a two-fold increase in the efficiency of rhodium was achieved as compared to nebulization. The detection limit was 6.9 μg/L, which is slight better than that of with nebulization. The linear range for rhodium was 20-1500 μg/L with a correlation coefficient of 0.9986. The mean recovery of sample analysis was 95.5%. Excellent agreement was found between the present method and FAAS.