1.The value of emergency sonography in the diagnosis of patients with abdominal trauma
Jian LIU ; Zhenchai LI ; Lingdi DU
Medical Journal of Chinese People's Liberation Army 2001;0(12):-
Objective To assess the value of emergency ultrasound in the diagnosis of patients with abdominal trauma. Methods Retrospective study was performed on 245 patients with abdominal trauma. All patients were examined with emergency ultrasound, and their sonographic findings were compared with their CT and operative findings. Results 1) Abnormal signs suggestive of injury were detected in 346 organs among 245 patients, and correct diagnosis was made in 299 cases, while misdiagnosis occurred in 47. The overall accuracy of sonographic diagnosis was 86.4%. 2) The accuracy rate of sonographic diagnosis of various organs: for splecn, liver, kidney, mesentery, bladder, retroperitoneal injuries were 93.4%, 91.9%, 80.9% and 51.3% respectively. 3) The accuracy of sonography on the free fluid and retroperitoneal fluid were 100% (213/213) and 89.5% (51/57) respectively. Conclusion Emergency sonography to evaluate patients for injury caused by abdominal trauma is highly accurate.
3.Quantized Study of Thoracic Vertebra with Different Rotational Degrees
Chinese Journal of Rehabilitation Theory and Practice 2008;14(12):1187-1189
Objective To probe into the quantizing rule of the thoracic vertebra rotation.Methods6 healthy corpses specimen were fixed on a wooden apparatus and rotated from 0° to 90° for X-ray examination.A X-ray examination was taken at each 5° rotational point.The characteristic of the image at each examinational point was observed.ResultsThere was radiology characteristic at each rotational point.ConclusionThe thoracic vertebra rotational degree could be quantized by X-ray examinations.
4.Application of the cervical back muscle trainer in the cervical back muscle exercise
Chinese Journal of Rehabilitation Theory and Practice 2006;12(5):445-446
ObjectiveTo investigate the effect of a cervical back muscle trainer. MethodsA cervical back muscle trainer designed by ourself was used in 128 patients with different kinds of cervical spondylosis. The situation of pain and activity of daily life of the patients before and 1 month after treatment were recorded and compared. ResultsThe neck pain of all of the patients nearly completely disappeared in a month and their activity of daily life improved significantly(P<0.01). ConclusionThe cervical back muscle trainer can improve the stability of cervical vertebrae through increasing the strength of the cervical back muscle, which can be used as an assistant rehabilitation approach of all kinds of cervical spondylosis.
5.MRI study on the surface area of occipital lobe in children with ametropic amblyopia
Han-Jian DU ; Jian WANG ; Bing XIE ; Li CHEN ;
Ophthalmology in China 2006;0(05):-
Objective Using MRI techniques and the FreeSurfer software package to research the occipital lobe's surface area in children with ametropic amblyopia.Design Prospective,nonrandomized clinical trial.Participants The amblyopic group included 10 children with ametropic amblyopia.The control group included 10 children with normal sight.Methods The brain MRI scan was per- formed with SIEMENS AVANTO 1.5 Tesla scanner.For the surface area analysis,3-demensional MPRAGE images were analyzed with FreeSurfer software package.Main Outcome Measures Occipital lobe related surface area(cuneus,later occipital,lingual,perical- carine)of bilateral hemisphere.Results No difference was between the ages of the two groups.The surface areas of the lingual,pefical- carine,cuneus of bilateral hemisphere and lateraloccipital on the left hemisphere in amblyopic patients were smaller than those of nor- real children(P
6.A magnetic resonance imaging study of the gray matter configuration in amnestic mild cognitive impairment patients
Chuanming LI ; Li GUI ; Hanjian DU ; Bing XIE ; Jian WANG
Chinese Journal of Neurology 2010;43(12):853-857
Objective To investigate the cortex gray matter configuration in amnestic mild cognitive impairment(aMCI)patients using MRI technology, FMRIB software library(FSL)and Freesurfer software.Methods Twenty aMCI patients and 20 normal control subjects were recruited and studied. They were matched by age, sex and education. All the patients and healthy volunteers underwent MRI scan using SEMENTS trio 3.0 T MRI. The subtile three-dimensional brain images were obtained using high resolution scanning technique. The imaging data was processed and analyzed with FSL and Freesurfer software. The cortex gray matter density and thickness in different brain areas of aMCI patients and normal control subjects were calculated and compared using statistic analysis. Results Compared to that in the controls, cortex gray matter density in the aMCI patients showed remarkable decreases in left frontal lobe, temporal lobe,parietal lobe, and slight decrease in right thalamus, temporal lobe and island lobe; For cortex thickness,aMCI patients showed significant decreases in left anterior cingulate gyrus((2. 19 ±0. 24)mm), inferior parietal lobe((2. 27 ± 0. 15)mm), bilateral parahippocampal gyrus((2. 03 ± 0. 15),(2. 04 ±0. 17)mm), precentral gyrus((2. 20 ± 0. 11),(2. 31 ± 0. 19)mm), postcentral gyrus((1.88 ± 0. 11),(1.82 ± 0. 09)mm), superior frontal gyrus((2. 42 ± 0. 34),(2. 40 ± 0. 28)mm), middle frontal gyrus ((2.31±0.31),(2.33 ±0.29)mm), supramarginal gyrus((2.53 ±0.33),(2.55 ±0.23)mm),temporal pole((3.41 ±0.68),(3.30 ±0.56)mm)and transverse temporal gyrus((2.04 ±0. 12),(2. 01 ± 0. 11)mm; t = 2. 13-3.75, P < 0. 05), no significant changes in the other areas(t = 0. 09-1.88, P > 0. 05). Conclusions Our results suggest that there are significant changes in gray matter configuration in cortex of aMCl patients. The changes of cortical thickness is earlier than the changes of gray matter density.
7.Research about perilla oil-induced human breast cancer cell line MCF 7 apoptosis
Yurou DU ; Jumei ZHAO ; Shengjun ZHANG ; Jian LI ; Minli LIU
Chongqing Medicine 2014;(21):2753-2755,2758
Objective To investigate perilla oil on human breast cancer MCF7 cell growth inhibition and induction of apoptosis , and provide a theoretical basis for the development of perilla oil anti-tumor .Methods Breast cancer MCF7 cells were treated with different dilutions of perilla oil to do tumor cell growth inhibition MTT experiment ,to observe the changes in the nuclear morpholo-gy of apoptotic cells with Hoechst 33258 and PI staining and fluorescence microscopy ,and to detect rate of apoptosis and apoptotic peak with flow cytometry .Results Perilla oil inhibited the proliferation on human breast cancer cell line MCF7 with a time-and concentration-dependent manner .Typical apoptotic nuclear morphological changes could be observed with Hoechst 33258 and PI staining under a fluorescence microscope .Detected by flow cytometry ,apoptosis rate was increased with time and concentration . Conclusion Perilla oil can inhibit human breast cancer MCF7 cell proliferation and induce apoptosis ,suggesting that it may be used as an anticancer drug in clinical practice .
8.The value of ankylosing spondylitis disease activity score in evaluating disease activity of ankylosing spondylitis
Xuna DU ; Yan LI ; Shengli ZHANG ; Jian ZHU ; Feng HUANG
Chinese Journal of Internal Medicine 2012;51(3):206-209
Objective To investigate the value of ankylosing spondylitis(AS)disease activity score (ASDAS)and the Bath AS disease activity index(BASDAI)in evaluating disease activity in AS.Methods ASDAS and BASDAI were used to evaluate disease activity in patients with AS,taking the patients' global scores,physician global scores and treatment decision as the “gold standard” for disease activity.According to the “gold standard”,the patients were divided into low and high disease activity groups.Statistical analysis included descriptive statistics,linear correlation and regression and ROC curve.Results A total of 227 patients with AS were included.ASDAS and BASDAI showed good correlation with disease activity as reflected by the patients' global score[r for BASDAI,ASDAS based on ESR(ASDAS-ESR)and ASDAS based on C-reactive protein(ASDAS-CRP)were 0.713,0.698 and 0.725,respectively,P =0.000]and the physician global score(r for BASDAI,ASDAS-ESR and ASDAS-CRP were 0.771,0.782,0.847,respectively,P =0.000).Both scores showed good discriminative ability for high and low disease activity states.ASDAS-CRP had the highest sensitivity.Conclusion ASDAS is a promising tool for evaluating disease activity in AS patients.
9.Anxiety and depression among the medical staff of a children's hospital
Hongying LI ; Yue ZHANG ; Jian TANG ; Xiaoke ZHAO ; Senjie DU
Chinese Journal of Physical Medicine and Rehabilitation 2015;37(11):861-866
Objective To explore the prevalence of anxiety and depression among the medical staff of a children's hospital, and to understand their relationship with age, gender, educational background, family income, family harmony, position, marital status, experience, title, work pressure, weekly working hours, chronic diseases and stressful events.Methods The medical staff of a children's hospital were evaluated using Zung's self-rating anxiety scale (SAS) and self-rating depression scale (SDS).The scores were correlated with age, gender, educational background, family income, family harmony, position, marriage, working years, title, work pressure, weekly working hours, chronic diseases, and stressful events data collected about the same respondents.Results There were 320 respondents suffering from anxiety disorders and 392 experiencing depression among the 677 medical staff surveyed.There were 288 who suffered from anxiety associated with depression.There was a significant difference between the males and the females.Marital status, family harmony, chronic disease and stress events were all significant predictors of anxiety or depression.A univariate analysis showed that neither education nor family income had significant predictive power, but age, professional title,working years, working pressure and working in different departments were all significant predictors.Medical staff with different weekly working hours showed significantly different average levels of anxiety, but position had no such effect.Position was, though, significantly correlated with depression score, while weekly working hours were not.Multivariable logistic regression models showed that educational background, working pressure, family harmony, chronic disease and stressful events were all significant predictors of anxiety.Working pressure, family harmony and chronic disease were related to depression.Conclusion Significant anxiety and depression were observed among the medical staff of this children's hospital.Working pressure, family harmony and chronic disease are strong predictors of anxiety and depression.
10.Advances of non-invasive detection of intracranial pressure
Zhenwei DU ; Jian SUN ; Mingxin QIN ; Shangbin LI ; Zhao ZHANG
International Journal of Biomedical Engineering 2014;37(5):307-310
In recent years,with the increasement of intracranial pressure detection accuracy,the use of intracranial pressure detection in clinic become more common.Various of technologies are used in clinic that can be divided into invasive methods,such as epidural catheter,subarachnoid bolt,intraventricular catheter,fiberoptic catheter and micro-sensors transducer,and non-invasive methods,such as evoked otoacoustic emissions,transocular method,transcranial doppler,imaging method and magnetic induction method.This paper reviews the physiological basis of intracranial pressure detection and common intracranial pressure detection techniques,especially on noninvasive intracranial pressure detection methods.Advantages and disadvantages of different intracranial pressure detection methods are listed,and an outlook of the development of non-invasive intracranial pressure detection technology are made.