1.Treatment of Compensatory Hyperhidrosis with Botulinum Toxin A: A case report.
Sang Ho SHIN ; Eun Young SHIN ; Du Hwan KIM ; Jeong Hun SUH ; Jung Gil LEEM ; Jin Woo SHIN
The Korean Journal of Pain 2009;22(3):253-256
Conventional thoracoscopic sympathectomy is an effective method in treating palmar-axillary hyperhidrosis. However, this may result in a postoperatively compensatory hyperhidrosis. Conservative treatments of compensatory hyperhidrosis consist of aluminum chloride, anticholinergics, iontrophoresis, and botulinum toxin A injections. Surgical treatments in compensatory hyperhidrosis include excision of axillary tissue, liposuction, and thoracoscopic sympathectomy. Intradermal injection of botulinum toxin A has used to treat focal axillary or palmar hyperhidrosis. Botulinum toxin A bestows significant benefits with few side-effects and is well-tolerated, with beneficial results lasting from 4-16 months. We report a case illustrating the beneficial use of botulinum toxin A in a 25-year-old healthy male patient with compensatory sweating of the flank after thoracoscopic sympathectomy. Modified Minor's starch iodine test was used to allow accurate assess the impact of hyperhidrosis on the patient. In conclusion, Botulinum toxin type A is a valuable therapy for compensatory sweating after endoscopic thoracic sympathectomy.
Adult
;
Aluminum
;
Aluminum Compounds
;
Botulinum Toxins
;
Botulinum Toxins, Type A
;
Chlorides
;
Cholinergic Antagonists
;
Humans
;
Hyperhidrosis
;
Injections, Intradermal
;
Iodine
;
Lipectomy
;
Male
;
Starch
;
Sweat
;
Sweating
;
Sympathectomy
2.Predictors of Voiding Dysfunction after Mid-urethral Sling Surgery for Stress Urinary Incontinence.
Jin Wook KIM ; Du Geon MOON ; Jung Ho SHIN ; Jae Hyun BAE ; Jeong Gu LEE ; Mi Mi OH
International Neurourology Journal 2012;16(1):30-36
PURPOSE: Postoperative voiding dysfunction is a bothersome complication after mid-urethral sling surgery. The current study presents multiple repeated postoperative voiding trials against a urine load of preoperative functional bladder capacity, as estimated by a preoperative frequency volume chart, to identify the relevance of preoperative and immediate factors to the outcome. METHODS: A total of 180 patients were enrolled from August 2008 to August 2011. Patients received mid-urethral sling surgery with a transobturator tape, with or without concomitant cystocele repair. Patients reported relevant medical histories and a 3-day frequency volume chart and underwent urodynamic studies. After surgery, patients were filled to their maximum bladder capacity as dictated by their frequency volume chart and performed the first voiding trial. Two subsequent voiding trials were performed after natural filling. Failure of any single voiding trial was considered failure. Patients who failed the final voiding trial received intermittent catheterization to follow-up. After screening for relevant factors with the use of univariate analyses, preoperative, surgical, and postoperative factors predicting outcome were estimated by logistic regression analysis. RESULTS: The urine load at the voiding trial and the peak flow rate immediately preceding the voiding trial predicted voiding trial success in the multivariate analysis. Urine load and previous trial peak flow rate were relevant when tested against each individual voiding trial. Preoperative and surgical factors, such as age, parity, and concomitant cystocele repair, showed significance in the univariate analysis. Overall, 16.1% of patients who passed the first voiding trial failed on subsequent trials, whereas 36.8% of patients who failed the first voiding trial succeeded. CONCLUSIONS: Postoperative voiding dysfunction is transient and is associated with the immediate voiding conditions following surgery. Close observation against urine overload in the bladder is important when weaning patients back to normal voiding conditions.
Catheterization
;
Catheters
;
Cystocele
;
Female
;
Follow-Up Studies
;
Humans
;
Logistic Models
;
Mass Screening
;
Multivariate Analysis
;
Parity
;
Suburethral Slings
;
Urinary Bladder
;
Urinary Incontinence
;
Urinary Retention
;
Urodynamics
;
Weaning
3.A study on intestinal lesions of experimentally reinfected dogs with Metagonimus yokogawai.
Shin Yong KANG ; Seung Yull CHO ; Jong Yil CHAI ; Jung Bin LEE ; Du Hwan JANG
The Korean Journal of Parasitology 1983;21(1):58-74
The intestinal lesions were studied in dog metagonimiasis by reinfection. The metacercariae of M. yokogawai were collected from naturally infected sweetfish. A total of twenty dogs were divided into three groups; control, primary infection and reinfection groups. The 18 dogs were infected with 10,000 metacercariae; the 5 dogs in primary infection group were killed at the 5 days in 1 week, 4 weeks, 6 weeks after the infection. The remaining 13 dogs were kept for nine weeks, and challenged again with 5,000 metacercaricae. The reinfected dogs were killed at the 1 day, 3 days, 5 days and 1 week, 2 weeks, 4 weeks, 6 weeks, 8 weeks respectively. The chronologic changes of the intestinal lesions in both groups, the worm recovery rate, and distribution patten were examined by gross observation, light and scanning electron microscopies. From the results, it was inferred that the so-called spontaneous and/or self cure phenomena were of negligible importance in metagonimiasis in dogs. In the chronologic observations of pathologic process in intestine, it was also suggested that the host immunity tend to recover the intestinal integrity. And early invasion of young worm to the Lieberkuhn's crypt was considered as the primary cause of lesions of vill(Abstract is summarized again.)
parasitology-helminth-trematoda
;
Metagonimus yokogawai
;
metagonimiasis
;
dog
;
histology
;
pathology
;
electron microscopy
;
intestine
4.Anomalous Systemic Arterial Supply to Normal Basal Segments of Left Lower Lobe: A Report of Two Cases.
Ki Man LEE ; Jong Joon AHN ; In Du JEONG ; Byung Chul KIM ; Je Kyoun SHIN ; Jong Pil JUNG ; Jae Cheol HWANG ; Jae Hee SUH
Tuberculosis and Respiratory Diseases 2001;50(6):710-717
Two cases of an anomalous systemic arterial supply to the basal segments of the left lower lobe without pulmonary wequestration are presented. In the first case, a preoperative diagnosis was made by chest CT, and confirmed by angiograpy, in a 22-year old man who had a recurrent hemoptysis. There was systemic arterial supply that originated from the thoracic descending aorta and no pulmonary arterial supply to the basilar segment of the left lower lobe. However, the pulmonary parenchyma was normal without sequestration. Ligation of the abnormal artery and a left lower lobectomy were performed without complication. In the second case, there were characteristic features of this anomaly on chest CT and the angiogram in a 31-year-old man with symptoms of hemoptysis. The patient refused surgery.
Adult
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Aorta, Thoracic
;
Arteries
;
Bronchopulmonary Sequestration
;
Diagnosis
;
Hemoptysis
;
Humans
;
Ligation
;
Tomography, X-Ray Computed
5.Two Cases of Retinal Hemorrhage in Alcoholic Cirrhosis.
Young Shin KIM ; Du Ri SEO ; Jung Woo HAN ; Tae Kwann PARK ; Young Hoon OHN
Journal of the Korean Ophthalmological Society 2015;56(8):1284-1288
PURPOSE: To report 2 cases of retinal hemorrhage due to anemia and thrombocytopenia in patients with alcoholic cirrhosis. CASE SUMMARY: (Case 1) A 45-year-old female with alcoholic cirrhosis who was treated in the gastroenterology department presented with reduced vision in both eyes. Fundus examination showed multiple preretinal and subretinal hemorrhages with macular involvement in both eyes. Hematological findings revealed severe anemia and thrombocytopenia. One month after the transfusion treatment her visual acuity was improved and retinal hemorrhages resolved. (Case 2) A 47-year-old male presented with painless loss of vision in the left eye 3 days after orthotopic liver transplantation for the treatment of alcoholic cirrhosis. Fundus examination showed preretinal hemorrhages in both eyes with macular involvement in the left eye. During the transplantation, hematological findings revealed severe anemia and thrombocytopenia. Three months after the transfusion treatment his visual acuity was improved and retinal hemorrhages nearly completely resolved. CONCLUSIONS: Hematological abnormalities due to alcoholic cirrhosis can cause retinal hemorrhage. In the present cases the retinal hemorrhages were resorbed and the visual acuity recovered.
Alcoholics*
;
Anemia
;
Female
;
Gastroenterology
;
Hemorrhage
;
Humans
;
Liver Cirrhosis, Alcoholic*
;
Liver Transplantation
;
Male
;
Middle Aged
;
Retinal Hemorrhage*
;
Retinaldehyde*
;
Thrombocytopenia
;
Vision, Low
;
Visual Acuity
6.Recurrent Hypertensive Intracerebral Homorrhage.
Hack Gun BAE ; Du Shin JUNG ; Jae Won DOH ; Kyeong Seok LEE ; Il Gyu YUN
Journal of Korean Neurosurgical Society 1999;28(3):335-339
The purpose of this study is to characterize the recurrence and to investigate the risk factors for the recurrence in the 989 patients who had hypertensive intracerebral hemorrhage between 1989-1995. Fifty-three patients(5.4%) had two episodes of hemorrhage with median interval of 22.3+16.3 months(range, 1.7-71.9 months). The probable risk of recurrent hemorrhage was the highest within two years of the first hemorrhage, being 3.6 % in the first year and 3.5 % in the second year. The sites of the recurrent hemorrhage were different from the initial site in all patients. The common patterns of recurrence were "ganglionic(putamen/caudate nucleus)-thalamic" in 26.8% and "ganglionic-ganglionic in 21.4%. The "lobar-lobar" pattern was noted in only 2 patients, The overall mortality was 28.3%. In patients who had ganglionic-ganglionic pattern, the mortality was significantly inc reased (p<0.005). No recurrent hemorrhage occurred during the regular treatment for hypertension. The only significant tactor for recurrent hemorrhage was the antihypertensive therapy of less than 3 months after the initial attack(p<0.005). Considering lifelong treatment for hypertension, long-term regular control for hypertension will be required to prevent the recurrent hemorrhage.
Hemorrhage
;
Humans
;
Hypertension
;
Intracranial Hemorrhage, Hypertensive
;
Mortality
;
Recurrence
;
Risk Factors
7.Acute Sialadenitis in Children and Adolescents: CT Findings and Clinical Manifestations according to Glandular Involvement.
A Leum LEE ; Young Tong KIM ; Jong Kyu HAN ; Sung Shick JOU ; Du Shin JUNG
Journal of the Korean Radiological Society 2008;59(3):155-161
PURPOSE: This study was designed to compare the CT findings and clinical manifestations in children and adolescents with acute sialadenitis according to the involved salivary glands. MATERIALS AND METHODS: The study included fifty children and adolescents (34 boys, 16 girls) with acute sialadenitis that was diagnosed during the past five years. All of the subjects were divided into three groups: group I (parotid gland involvement, n = 16), group II (submandibular gland involvement, n = 20) and group III (involvement of both glands, n = 14). We analyzed the presence of an abscess, sialolith, bilaterality, cellulitis and lymphadenopathy on CT scans. The analyzed clinical data were age, sex, lymphadenopathy, pain, swelling, presence of a mass, tonsillitis, treatment period and surgical treatment if it was performed. RESULTS: The presence of an abscess, sialolith, cellulitis, swelling, age, presence of a palpable mass and treatment period were statistically significant factors for the patients in the three groups. An abscess was combined only in group I patients. There was a high rate of sialolith in group II patients and cellulitis in group III patients as seen on CT scans. Swelling in group II patients and group III patients and the presence of a palpable mass in group I patients were identified as clinical manifestations. Age was younger in group I patients (mean age, 5.3 years) than in group II patients (mean age, 12.9 years) and group III patients (mean age, 15.2 years). The treatment period was longer for group I patients. CONCLUSION: For acute sialadenitis in children and adolescents, age, presence of an abscess, sialolith, cellulitis, swelling, presence of a palpable mass and treatment period were different according to the involved salivary glands.
Abscess
;
Adolescent
;
Cellulitis
;
Child
;
Humans
;
Lymphatic Diseases
;
Palatine Tonsil
;
Salivary Gland Calculi
;
Salivary Glands
;
Sialadenitis
;
Tonsillitis
8.A Case of Colonic Duplication Cyst Mimicking Gastrointestinal Stromal Tumor.
Hee Chul JUNG ; Seok Won JUNG ; In Du JEONG ; Sung Jo BANG ; Jung Woo SHIN ; Neung Hwa PARK ; Young Min KIM ; Dae Hwa CHOI ; Do Ha KIM
Intestinal Research 2009;7(1):64-67
Duplications of the gastrointestinal tract are rare congenital malformations that are usually present during the first decade of life. However, a smaller number of cases may remain occult until adulthood. Overall, the colon is the least common site of congenital gastrointestinal duplications. Colonic duplications can present with symptoms of diverticulitis and can be confused with acquired giant cysts or masses. We present a rare case of a duplication cyst of the colon in a female adult. Although the preoperative evaluations, including an abdominal CT scan and colonoscopy, were suggestive of a gastrointestinal tumor of the colon, the final diagnosis was a colonic duplication cyst based on the histopathologic examination of the resected specimen. Even if intestinal duplication cysts are uncommon, they should be considered in the differential diagnosis of intestinal masses.
Adult
;
Colon
;
Colonoscopy
;
Diagnosis, Differential
;
Digestive System Abnormalities
;
Diverticulitis
;
Female
;
Gastrointestinal Stromal Tumors
;
Gastrointestinal Tract
;
Humans
9.A Case of Thymic Carcinoma with Behcet's Disease Combined with Immunoglobulin A Nephropathy.
Se Hee PARK ; Jung Ho KIM ; Jung Yoen LEE ; Sug Kyun SHIN ; Yong Kook HONG ; Jeong Hae KIE ; Du Yong KANG ; Chan Hee LEE
Journal of Rheumatic Diseases 2015;22(2):118-122
Behcet's disease is a systemic inflammatory disorder of unknown etiology, characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions. Renal involvement is rare in patients with Behcet's disease particularly immunoglobulin A (IgA) nephropathy. Other autoimmune diseases have been associated with increased risk of malignancy, but not Behcet's disease. Some cases of Behcet's disease accompanied by bladder cancer, thyroid cancer, stomach cancer, or hematologic malignancies have been reported. However, to the best of our knowledge, co-occurrence of Behcet's diseases with thymic carcinoma has not yet been reported. We experienced a 49-year-old male patient who had been treated for Behcet disease and IgA nephropathy, who presented with a large mediastinal mass on chest x-ray. After thymectomy, he was diagnosed with thymic carcinoma with complete resection.
Autoimmune Diseases
;
Behcet Syndrome
;
Glomerulonephritis, IGA*
;
Hematologic Neoplasms
;
Humans
;
Immunoglobulin A
;
Male
;
Middle Aged
;
Skin
;
Stomach Neoplasms
;
Stomatitis, Aphthous
;
Thorax
;
Thymectomy
;
Thymoma*
;
Thyroid Neoplasms
;
Ulcer
;
Urinary Bladder Neoplasms
;
Uveitis
10.Expression of Vascular Endothelial Growth Factor, Microvessel Density and Prognosis in Epithelial Ovarian Tumors.
Seong Lan CHOI ; Ji Young KIM ; Il Woong PARK ; Hyun Chul JUN ; Du Suck JUNG ; Joong Dong CHO ; Hyung Seok KIM ; Ji Shin LEE ; Jong Jae JUNG ; Ho Sun CHOI
Korean Journal of Obstetrics and Gynecology 2003;46(3):559-567
OBJECTIVE: It is still unclear whether angiogenic potential, which is believed to be a prerequisite for tumor development, is an important prognostic factor in ovarian carcinoma. The current study was designed to examine the relationship among Vascular endothelial growth factor (VEGF) expression, angiogenesis in ovarian neoplasms and clinicopathological prognostic variables. METHODS: A according to the WHO classification and FIGO staging epithelial ovarian carcinoma was classified. Microvessel density and VEGF status were evaluated by immunohistochemistry in 77 epithelial ovarian carcinomas. RESULTS: Positive immunostaining for VEGF was observed in 92.6% (50 out of 54) of ovarian carcinomas, which was significantly higher than that of low malignant potential (LMP) tumors (12 out of 23; 52.2%) (p<0.001). In ovarian carcinomas, positive VEGF immunostaining was also observed more frequently, even though not significantly, in tumor of elder age group (more than 60 years) (p=0.05) and less differentiated (p=0.05). CD34 immunostaining revealed increased microvessel density in ovarian carcinomas larger than 10 cm in size (p=0.029) and in mucinous type tumors (p=0.025). Microvessel counts of epithelial ovarian carcinomas examined were not correlated with VEGF expression. Histologic type (p=0.0428), differentiation (p=0.0083) and FIGO stage (p=0.0004) also influenced overall survival of ovarian carcinomas in univariate analysis. But multivariate analysis revealed that disease stage was the only significant and independent prognostic factor of ovarian carcinomas (p=0.001). In advanced ovarian tumors (stage III/IV), microvessel density was the only significant prognostic factor (p=0.002). CONCLUSION: Therefore, the expression of VEGF could be used as an adjuvant indicator of differing borderline tumor from ovarian carcinoma. And microvessel density of advanced ovarian carcinoma may enhance the predictability of patient at high risk for tumor progression who are potential candidate for further aggressive therapy.
Classification
;
Humans
;
Immunohistochemistry
;
Microvessels*
;
Mucins
;
Multivariate Analysis
;
Ovarian Neoplasms
;
Prognosis*
;
Vascular Endothelial Growth Factor A*