1.Treatment of Compensatory Hyperhidrosis with Botulinum Toxin A: A case report.
Sang Ho SHIN ; Eun Young SHIN ; Du Hwan KIM ; Jeong Hun SUH ; Jung Gil LEEM ; Jin Woo SHIN
The Korean Journal of Pain 2009;22(3):253-256
Conventional thoracoscopic sympathectomy is an effective method in treating palmar-axillary hyperhidrosis. However, this may result in a postoperatively compensatory hyperhidrosis. Conservative treatments of compensatory hyperhidrosis consist of aluminum chloride, anticholinergics, iontrophoresis, and botulinum toxin A injections. Surgical treatments in compensatory hyperhidrosis include excision of axillary tissue, liposuction, and thoracoscopic sympathectomy. Intradermal injection of botulinum toxin A has used to treat focal axillary or palmar hyperhidrosis. Botulinum toxin A bestows significant benefits with few side-effects and is well-tolerated, with beneficial results lasting from 4-16 months. We report a case illustrating the beneficial use of botulinum toxin A in a 25-year-old healthy male patient with compensatory sweating of the flank after thoracoscopic sympathectomy. Modified Minor's starch iodine test was used to allow accurate assess the impact of hyperhidrosis on the patient. In conclusion, Botulinum toxin type A is a valuable therapy for compensatory sweating after endoscopic thoracic sympathectomy.
Adult
;
Aluminum
;
Aluminum Compounds
;
Botulinum Toxins
;
Botulinum Toxins, Type A
;
Chlorides
;
Cholinergic Antagonists
;
Humans
;
Hyperhidrosis
;
Injections, Intradermal
;
Iodine
;
Lipectomy
;
Male
;
Starch
;
Sweat
;
Sweating
;
Sympathectomy
2.Acute Sialadenitis in Children and Adolescents: CT Findings and Clinical Manifestations according to Glandular Involvement.
A Leum LEE ; Young Tong KIM ; Jong Kyu HAN ; Sung Shick JOU ; Du Shin JUNG
Journal of the Korean Radiological Society 2008;59(3):155-161
PURPOSE: This study was designed to compare the CT findings and clinical manifestations in children and adolescents with acute sialadenitis according to the involved salivary glands. MATERIALS AND METHODS: The study included fifty children and adolescents (34 boys, 16 girls) with acute sialadenitis that was diagnosed during the past five years. All of the subjects were divided into three groups: group I (parotid gland involvement, n = 16), group II (submandibular gland involvement, n = 20) and group III (involvement of both glands, n = 14). We analyzed the presence of an abscess, sialolith, bilaterality, cellulitis and lymphadenopathy on CT scans. The analyzed clinical data were age, sex, lymphadenopathy, pain, swelling, presence of a mass, tonsillitis, treatment period and surgical treatment if it was performed. RESULTS: The presence of an abscess, sialolith, cellulitis, swelling, age, presence of a palpable mass and treatment period were statistically significant factors for the patients in the three groups. An abscess was combined only in group I patients. There was a high rate of sialolith in group II patients and cellulitis in group III patients as seen on CT scans. Swelling in group II patients and group III patients and the presence of a palpable mass in group I patients were identified as clinical manifestations. Age was younger in group I patients (mean age, 5.3 years) than in group II patients (mean age, 12.9 years) and group III patients (mean age, 15.2 years). The treatment period was longer for group I patients. CONCLUSION: For acute sialadenitis in children and adolescents, age, presence of an abscess, sialolith, cellulitis, swelling, presence of a palpable mass and treatment period were different according to the involved salivary glands.
Abscess
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Adolescent
;
Cellulitis
;
Child
;
Humans
;
Lymphatic Diseases
;
Palatine Tonsil
;
Salivary Gland Calculi
;
Salivary Glands
;
Sialadenitis
;
Tonsillitis
3.Anomalous Systemic Arterial Supply to Normal Basal Segments of Left Lower Lobe: A Report of Two Cases.
Ki Man LEE ; Jong Joon AHN ; In Du JEONG ; Byung Chul KIM ; Je Kyoun SHIN ; Jong Pil JUNG ; Jae Cheol HWANG ; Jae Hee SUH
Tuberculosis and Respiratory Diseases 2001;50(6):710-717
Two cases of an anomalous systemic arterial supply to the basal segments of the left lower lobe without pulmonary wequestration are presented. In the first case, a preoperative diagnosis was made by chest CT, and confirmed by angiograpy, in a 22-year old man who had a recurrent hemoptysis. There was systemic arterial supply that originated from the thoracic descending aorta and no pulmonary arterial supply to the basilar segment of the left lower lobe. However, the pulmonary parenchyma was normal without sequestration. Ligation of the abnormal artery and a left lower lobectomy were performed without complication. In the second case, there were characteristic features of this anomaly on chest CT and the angiogram in a 31-year-old man with symptoms of hemoptysis. The patient refused surgery.
Adult
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Aorta, Thoracic
;
Arteries
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Bronchopulmonary Sequestration
;
Diagnosis
;
Hemoptysis
;
Humans
;
Ligation
;
Tomography, X-Ray Computed
4.Recurrent Hypertensive Intracerebral Homorrhage.
Hack Gun BAE ; Du Shin JUNG ; Jae Won DOH ; Kyeong Seok LEE ; Il Gyu YUN
Journal of Korean Neurosurgical Society 1999;28(3):335-339
The purpose of this study is to characterize the recurrence and to investigate the risk factors for the recurrence in the 989 patients who had hypertensive intracerebral hemorrhage between 1989-1995. Fifty-three patients(5.4%) had two episodes of hemorrhage with median interval of 22.3+16.3 months(range, 1.7-71.9 months). The probable risk of recurrent hemorrhage was the highest within two years of the first hemorrhage, being 3.6 % in the first year and 3.5 % in the second year. The sites of the recurrent hemorrhage were different from the initial site in all patients. The common patterns of recurrence were "ganglionic(putamen/caudate nucleus)-thalamic" in 26.8% and "ganglionic-ganglionic in 21.4%. The "lobar-lobar" pattern was noted in only 2 patients, The overall mortality was 28.3%. In patients who had ganglionic-ganglionic pattern, the mortality was significantly inc reased (p<0.005). No recurrent hemorrhage occurred during the regular treatment for hypertension. The only significant tactor for recurrent hemorrhage was the antihypertensive therapy of less than 3 months after the initial attack(p<0.005). Considering lifelong treatment for hypertension, long-term regular control for hypertension will be required to prevent the recurrent hemorrhage.
Hemorrhage
;
Humans
;
Hypertension
;
Intracranial Hemorrhage, Hypertensive
;
Mortality
;
Recurrence
;
Risk Factors
5.Predictors of Voiding Dysfunction after Mid-urethral Sling Surgery for Stress Urinary Incontinence.
Jin Wook KIM ; Du Geon MOON ; Jung Ho SHIN ; Jae Hyun BAE ; Jeong Gu LEE ; Mi Mi OH
International Neurourology Journal 2012;16(1):30-36
PURPOSE: Postoperative voiding dysfunction is a bothersome complication after mid-urethral sling surgery. The current study presents multiple repeated postoperative voiding trials against a urine load of preoperative functional bladder capacity, as estimated by a preoperative frequency volume chart, to identify the relevance of preoperative and immediate factors to the outcome. METHODS: A total of 180 patients were enrolled from August 2008 to August 2011. Patients received mid-urethral sling surgery with a transobturator tape, with or without concomitant cystocele repair. Patients reported relevant medical histories and a 3-day frequency volume chart and underwent urodynamic studies. After surgery, patients were filled to their maximum bladder capacity as dictated by their frequency volume chart and performed the first voiding trial. Two subsequent voiding trials were performed after natural filling. Failure of any single voiding trial was considered failure. Patients who failed the final voiding trial received intermittent catheterization to follow-up. After screening for relevant factors with the use of univariate analyses, preoperative, surgical, and postoperative factors predicting outcome were estimated by logistic regression analysis. RESULTS: The urine load at the voiding trial and the peak flow rate immediately preceding the voiding trial predicted voiding trial success in the multivariate analysis. Urine load and previous trial peak flow rate were relevant when tested against each individual voiding trial. Preoperative and surgical factors, such as age, parity, and concomitant cystocele repair, showed significance in the univariate analysis. Overall, 16.1% of patients who passed the first voiding trial failed on subsequent trials, whereas 36.8% of patients who failed the first voiding trial succeeded. CONCLUSIONS: Postoperative voiding dysfunction is transient and is associated with the immediate voiding conditions following surgery. Close observation against urine overload in the bladder is important when weaning patients back to normal voiding conditions.
Catheterization
;
Catheters
;
Cystocele
;
Female
;
Follow-Up Studies
;
Humans
;
Logistic Models
;
Mass Screening
;
Multivariate Analysis
;
Parity
;
Suburethral Slings
;
Urinary Bladder
;
Urinary Incontinence
;
Urinary Retention
;
Urodynamics
;
Weaning
6.A study on intestinal lesions of experimentally reinfected dogs with Metagonimus yokogawai.
Shin Yong KANG ; Seung Yull CHO ; Jong Yil CHAI ; Jung Bin LEE ; Du Hwan JANG
The Korean Journal of Parasitology 1983;21(1):58-74
The intestinal lesions were studied in dog metagonimiasis by reinfection. The metacercariae of M. yokogawai were collected from naturally infected sweetfish. A total of twenty dogs were divided into three groups; control, primary infection and reinfection groups. The 18 dogs were infected with 10,000 metacercariae; the 5 dogs in primary infection group were killed at the 5 days in 1 week, 4 weeks, 6 weeks after the infection. The remaining 13 dogs were kept for nine weeks, and challenged again with 5,000 metacercaricae. The reinfected dogs were killed at the 1 day, 3 days, 5 days and 1 week, 2 weeks, 4 weeks, 6 weeks, 8 weeks respectively. The chronologic changes of the intestinal lesions in both groups, the worm recovery rate, and distribution patten were examined by gross observation, light and scanning electron microscopies. From the results, it was inferred that the so-called spontaneous and/or self cure phenomena were of negligible importance in metagonimiasis in dogs. In the chronologic observations of pathologic process in intestine, it was also suggested that the host immunity tend to recover the intestinal integrity. And early invasion of young worm to the Lieberkuhn's crypt was considered as the primary cause of lesions of vill(Abstract is summarized again.)
parasitology-helminth-trematoda
;
Metagonimus yokogawai
;
metagonimiasis
;
dog
;
histology
;
pathology
;
electron microscopy
;
intestine
7.Two Cases of Retinal Hemorrhage in Alcoholic Cirrhosis.
Young Shin KIM ; Du Ri SEO ; Jung Woo HAN ; Tae Kwann PARK ; Young Hoon OHN
Journal of the Korean Ophthalmological Society 2015;56(8):1284-1288
PURPOSE: To report 2 cases of retinal hemorrhage due to anemia and thrombocytopenia in patients with alcoholic cirrhosis. CASE SUMMARY: (Case 1) A 45-year-old female with alcoholic cirrhosis who was treated in the gastroenterology department presented with reduced vision in both eyes. Fundus examination showed multiple preretinal and subretinal hemorrhages with macular involvement in both eyes. Hematological findings revealed severe anemia and thrombocytopenia. One month after the transfusion treatment her visual acuity was improved and retinal hemorrhages resolved. (Case 2) A 47-year-old male presented with painless loss of vision in the left eye 3 days after orthotopic liver transplantation for the treatment of alcoholic cirrhosis. Fundus examination showed preretinal hemorrhages in both eyes with macular involvement in the left eye. During the transplantation, hematological findings revealed severe anemia and thrombocytopenia. Three months after the transfusion treatment his visual acuity was improved and retinal hemorrhages nearly completely resolved. CONCLUSIONS: Hematological abnormalities due to alcoholic cirrhosis can cause retinal hemorrhage. In the present cases the retinal hemorrhages were resorbed and the visual acuity recovered.
Alcoholics*
;
Anemia
;
Female
;
Gastroenterology
;
Hemorrhage
;
Humans
;
Liver Cirrhosis, Alcoholic*
;
Liver Transplantation
;
Male
;
Middle Aged
;
Retinal Hemorrhage*
;
Retinaldehyde*
;
Thrombocytopenia
;
Vision, Low
;
Visual Acuity
8.A Case of Colonic Duplication Cyst Mimicking Gastrointestinal Stromal Tumor.
Hee Chul JUNG ; Seok Won JUNG ; In Du JEONG ; Sung Jo BANG ; Jung Woo SHIN ; Neung Hwa PARK ; Young Min KIM ; Dae Hwa CHOI ; Do Ha KIM
Intestinal Research 2009;7(1):64-67
Duplications of the gastrointestinal tract are rare congenital malformations that are usually present during the first decade of life. However, a smaller number of cases may remain occult until adulthood. Overall, the colon is the least common site of congenital gastrointestinal duplications. Colonic duplications can present with symptoms of diverticulitis and can be confused with acquired giant cysts or masses. We present a rare case of a duplication cyst of the colon in a female adult. Although the preoperative evaluations, including an abdominal CT scan and colonoscopy, were suggestive of a gastrointestinal tumor of the colon, the final diagnosis was a colonic duplication cyst based on the histopathologic examination of the resected specimen. Even if intestinal duplication cysts are uncommon, they should be considered in the differential diagnosis of intestinal masses.
Adult
;
Colon
;
Colonoscopy
;
Diagnosis, Differential
;
Digestive System Abnormalities
;
Diverticulitis
;
Female
;
Gastrointestinal Stromal Tumors
;
Gastrointestinal Tract
;
Humans
9.Clinical Outcomes of Lamivudine Therapy in HBeAg Positive Chronic Hepatitis B with Minimally Elevated ALT.
Dong Ha HAN ; Neung Hwa PARK ; Jung Woo SHIN ; Seok Won JUNG ; Young Tae HWANG ; Hyun Soo KIM ; In Du JEONG ; Sung Jo BANG ; Do Ha KIM
The Korean Journal of Hepatology 2007;13(2):146-156
BACKGROUND/AIMS: The aim of this study was to compare the efficacy of lamivudine therapy between chronic hepatitis B (CHB) patients, whose ALT levels less than 2 times the upper limit of normal (ULN) and patients whose ALT levels are more than 2 times ULN. METHODS: We retrospectively analyzed 508 consecutive patients with HBeAg-positive CHB who were treated with lamivudine for 1 year or more. Forty-six patients (Group A) with pretreatment ALT levels less than 2 times ULN were retrospectively compared with 462 patients (Group B) whose ALT levels are more than 2 times ULN. RESULTS: HBeAg seroconversion was achieved in 15 (32.6%) of group A and 162 (35.1%) of group B. The cumulative rates of HBeAg seroconversion in group A and B were 19% and 21% at 12 months; 35% and 31% at 24 months; and 38% and 39% at 36 months, respectively. HBV breakthrough was observed in 20 (43.5%) of group A and 192 (41.6%) of group B. The cumulative breakthrough rates of group A and B were 18% and 12% at 12 months; 33% and 29 % at 18 months; 45% and 42% at 24 months, respectively. Post-treatment relapse in group A and B occurred in 56% (5/9) and 41% (44/108), respectively. Therefore, the rates of the HBeAg seroconversion, breakthrough, and post-treatment relapse were not significantly different between these two groups. CONCLUSIONS: Lamivudine therapy in HBeAg-positive CHB patients whose ALT levels are minimally elevated is as effective as in treatment of the patients whose pretreated ALT levels are twice more than ULN.
Adolescent
;
Adult
;
Aged
;
Alanine Transaminase/*analysis
;
Antiviral Agents/pharmacology/*therapeutic use
;
Drug Resistance, Viral
;
Female
;
Hepatitis B e Antigens/*analysis
;
Hepatitis B, Chronic/diagnosis/*drug therapy
;
Humans
;
Lamivudine/pharmacology/*therapeutic use
;
Male
;
Middle Aged
;
Prognosis
;
Treatment Outcome
10.Risk Factors for Lymph Node Metastasis after Endoscopic Resection for Early Colorectal Cancer.
Kyung Hoon LIM ; Seok Won JUNG ; In Du JEONG ; Sung Jo BANG ; Jung Woo SHIN ; Neung Hwa PARK ; Hye Jeong CHOI ; Dae Hwa CHOI ; Do Ha KIM
Intestinal Research 2008;6(2):103-109
BACKGROUND/AIMS: Although endoscopic resection is widely used for the treatment of early colorectal cancer, the risk factors for lymph node metastasis are not clear. This study was designed to determine the risk factors for lymph node metastasis in patients with colorectal cancer who are treated by endoscopic resection. METHODS: The medical records of patients with histologically-proven early colorectal cancers who were treated by endoscopic resection between January 2002 and September 2008 were retrospectively reviewed. Information regarding the demographic data of patients and the clinicopathologic characteristics were recorded and analyzed. RESULTS: Twenty-nine patients who underwent subsequent surgical treatment after endoscopic resection for early colorectal cancer were enrolled in this study. Six patients (20.7%) had lymph node metastases on surgical pathologic examination. The predictive factors for lymph node metastasis were tumor morphology (non-polypoid flat tumors [p=0.019]), absence of background adenomas (p=0.033), and deep submucosal invasion > or = 2,000 um (p=0.012). Unexpectedly, the presence of vascular invasion was not associated with lymph node metastasis. CONCLUSIONS: The presence of vascular invasion might not be an absolute indication for additional surgical treatment of early colorectal cancer; however, deep submucosal invasion, accompanied by a gross tumor with a non-polypoid flat morphology, and the absence of background adenomas are potential risk factors for lymph node metastasis.
Adenoma
;
Colorectal Neoplasms
;
Humans
;
Lymph Nodes
;
Lymphatic Metastasis
;
Medical Records
;
Neoplasm Metastasis
;
Retrospective Studies
;
Risk Factors