Objective A pronunciation aid device had been made by using dental prosthodontic method for the treatment of pronunciation disorder, which is caused by movement dysfunction because of defect of soft palate tissues in cleft lip and palate patients.Methods According to the defect condition in the mouth, two types of pronunciation aid devices had been produced regularly by using maxillary impression, plaster casting and thermoplastic resin materials and so on. Results In the first group of cases, after 3 patients were wearing soft palate movement pronunciation aid device, and then they were given pronunciation training, it is found that their language clearances degrees had been promoted obviously. In the second group of cases, 2 patients were wearing naso-pharynx cavity closing pronunciation aid device, it is found that their nasal sound and nasal leakage were disappeared. And in the same time we gave patients pronunciation training, and after one year, their language clearances degrees were found to be more obviously increased than before.Conclusions Naso-pharynx cavity closing pronunciation aid device and soft palate movement pronunciation aid device are an effective non-surgical treatment methods for the treatment of naso-pharynx cavity closing dysfunction and soft palate movement dysfunction.

Objective To observe the different efficacy of combination of inhaled ipratropium bromide and salbutamol and inhaling the two drugs separately. Methods Sixty -five patients with COPD were divided into 3 groups,and treated with different drugs. We observed the lung function FEV1 , the improvement of symptoms and side - effects. Results The FEV_1 and improvement of symptoms in combination group were significantly better than those in seperatin group (P

TCM boosts plenty theories and practice on delaying aging.Many TCM recognitions on the mechanism of female aging are still useful.The female has menstration,pregnancy,and lactation physiologically,which are different from the male,so the mechanism of the female aging is obviously different from the male.Many factors leads to female aging,such as the growth of age,interaction between deficiency,qi stagnation,blood stasis,and turbid phlegm,and results in functional retrogradation of the whole body.A deep discussion on the mechanism and law of female aging will bring about positive significance in the prevention and treatment of this disease.

Objective To know the related risk behaviour and counter nursing measures for patients with schizophrenia. Methods Investigated 162 patients with schizophrenia to know their disease-related risk behaviour. Results There were 48 patients had risk behaviour, 83.33% dangerous behaviour was occurred within 2 weeks after enter the hospital. Most dangerous behaviour such as uprash damage, self damage and went astray had occurred from 8:00 to 17:00, commit suicide often occurred from 12:00 to 14:00 or 17:00 to 8:00. Conclusions Evaluation in early stage, strengthen management, build up cooperated relationship between patients and nurses, carry out proper psychological nursing and avoid risk behaviour can effective protect patients with schizophrenia.

China ; Female ; Humans ; Neonatology ; ethics ; trends

Objective:To study the the correlation between the diameter or angle of thoracic-lumber pedicle and vertebral number.Method:X-ray and CT scan were performed on 46 male spine specimens.The length of pediele screw path,the cress-section angle(e) and the sagittal angle(f) of the pedicle,the width of the inner diameter of the pediele and the distance between the two pedicles were measured.The ordinal number of T1-L5 vertebral segment was numbered by 1-17.SPSS 11.5 software was used for statistical analysis.Result:The data showed a positive linear correlation with the vertebral numbers including length of T1-L4 pedicle screw path (R2=0.716),T8-L5 pedicle width (R2=0.673),T4-L5 pedicle distances (R2=0.771),T1-T2 f-angle (R2=0.767) ,T2-T4 f-angle (R2=0.908),T12-L5 pediele e-angle (R2=0.710).The negative linear correlation with thevertebral numbers included T2-T3 pedicle width(R2=0.792),T1-T4 pedicle distances(R2=0.866),T7-L5 f-an-gle(R2=0.931),T1-T6 pedicle e-angle (R2=0.774).However,the T1-T2 and T4-T7 pediele width,the T4-T6 pediele f-angle,as well as the T6-T12 pedicle e-angle had no significant correlation with the vertebral num-bers.Conclusion:Apart from the T1-T2 and T4-T7 pedicle width,the T4-T6 pedicle f-angle and the T6-T12 pedicle e-angle,the diameter or angle of the thoracic-lumbar pedicle have correlation with the vertebral numbers with meaningful linear regression equation.

Objective To raise final diagnosis of infant' tuberculosis of lungs and toreduce misdiagnosis by approaching baby' imaging appearance.Methods Analyzing 12 cases of infant' tuberculosis of lungs of final diagnosis during near two yeas.Results In 12 cases,8 cases were to cough up phlegm,5 cases were being breathlessness and to gasp for breath,10 cases have a temperature,hyperthermia was understanding 40 ℃,minimum was 38 ℃,4 cases have night sweat,5 cases were being symptomsis,5cases have symptom of nervous system, there were 3 cases with headache and hyperspasmia,1 case with conscious disturbance;All cases were examined by normal side projection,among these there are 6 cases were examined by plain scan and enhancement scanning of CT;There were 7cases with acute miliary tuberculosis,3 cases with primary complex,2 cases with mediastinal lymphadenectasis, 1case with pure mediastinal lymphadenectasis;1 case with secnd pulmonary tuberculosis,1 case with superior' pulmonary atelectasis lobe of left lung;3 cases with tuberculous meningoencephalitis,1 case with spinal tuberculosis,1 case with Tuberculous abdominal cavity,3 cases with pleural fluid and pleural thickening among 12 cases.Conclusion Earlier diagnosis can be reached according by Baby' imaging appearance and clinical symptom, to treat in time.

Objective To evaluate the clinical efficacy of neo-adjuvant chemotherapy in the treatment of cervical cancer. Methods A total of 32 patients,of which 12 cases of Ⅰ b2,8 cases of Ⅱ a,5 case of Ⅱ b and 7 cases of Ⅲ, were all treated with 2 - 3 cycles of PF chemotherapy before treatment with cisplatin 100 mg/m2, d 1;5-fluorouracil 1000 mg/m2 ,d1-5. The chemotherapy was performed for 3 weeks followed by three weeks rest as one cycle. Results Short-term effect was 81.3% (26/32), with 3 cases of Ⅰ b2 and 1 cases of Ⅱ a had been completely relieved after 2 - 3 cycles of chemotherapies. Simultaneously, chemotherapy improved the removal rate of surgery. Among these 32 patients, there were 4 cases achieved complete response (CR) ,22 cases achieved partial response (PR) ,5 case of stable disease ( SD), 1 cases of progressive disease(PD). The overall response rate( CR +PR) was 81.3% (26/32) ,and the control rate ( CR + PR + SD) was 96. 9% (31/32). The main adverse events included myelosuppression and gastrointestinal response, which were all tolerable. Conclusions The neo-adjuvant chemotherapy reduced the size of cancer,which can improve removal rate of surgery and the quality of life.

Objective To investigate the psycho-physiological characteristics of experimental tonic cold and heat pain in a behavioral study. Methods Sixty healthy subjects went through the tonic cold and tonic heat stimulation in a counter-balanced order. Psychological traits were measured before the experiment. Pain intensity ratings were recorded together with continuous Infrared thermal imaging recording. SF-MPQ was employed to assess pain intensity and affective measures. Results Anxiety and fear were positively correlated with cold pain intensity on SF-MPQ,while GESE was negatively correlated with that of heat pain (r =0.57,P <0.05; r =0.45,P <0.05,respectively). Verbal descriptors chosen from SF-MPQ for cold and heat pain significantly differed(χ2=18.6,P =0.04). Infrared thermal imaging results showed after stimulation,heat pain intensity ratings decreased simultaneously with skin surface temperature recovery to baseline. In contrast,skin surface temperature began to return to baseline well before the cold sensation began to diminish(t =34.57,P <0.05; t =23.66,P <0.05). Conclusion Experimental tonic cold and heat pain are not psychophysically identical,but may be predicted by different psychological traits,and may reside in differential peripheral and central processing in human.

Interleukin-22 (IL-22) is a new kind of eytokine discovered in 2000. The major sources of IL-22 are activated T1 -cells and NK-cells. Tissue cells at outer body barriers, i.e. of the skin, kidney, the di-gestive and respiratory systems all highly express IL-22R or respond to IL-22. IL-22 functions by promoting the anti-microbial defense, inducing phase reactants, protecting against damage and enhancing natural immu-nity. Furthermore, IL-22 mediates the proliferation, differentiation and apoptesis in cancer cells, that gives us a new idea about tumor therapy.