Various neurotransmitters have been proposed as possible mediators of penile erection. Especially, norepinephrine and serotonin might have a important role in sexual arousal and penile erection. And it could be hypothesized that the psychogenic impotence is associated with the depletion or imbalance of norepinephrine and serotonin from evidences such as the symptomatic manifestation of depression and the antidepressant-induced sexual dysfunction. The authors investigates the association of norepienphrine and serotonin with psychogenic impotence. The psychogenic impotent group(PIG) consisted of twenty-three patients with psychogenic impotence and the controlled group(CG) consisted of twenty-seven patients without psychogenic impotence. PIG had no organic cause accounting for their erectile dysfunction. The Beck Depression Inventory(BDI) and the State-Trait Anxiety Inventory(STAI) were applied to each subject to assess mood, state anxiety(SA) and trait anxiety(TA). Plasma norepinephrine level from systemic blood and 5-hydroxyindoleacetic acid(HIAA) levels from 24-hours urine were measured in each subject. The mean score of BDI of PIG was significantly higher than that of CG(p=0.015). PIG had a tendency of higher TA compared with CG(p=0.054). And also SA was higher in PIG, bud did not show significant difference(p=0.193). The level of norepinephrine was significantly lower in patient with psychogenic impotence(p=0.000). And the level of 24-hours urine 5-HIAA was lower in PIG but did not show significant difference(p=0.494). Although the authors did not exclude depressive disorders in PIG, the present findings suggest that psychogenic impotence might have higher depressive mood and trait anxiety, and be associated with the depletion of norepinephrine in systemic blood.
Anxiety ; Arousal ; Depression ; Depressive Disorder ; Erectile Dysfunction* ; Humans ; Hydroxyindoleacetic Acid ; Male ; Neurotransmitter Agents ; Norepinephrine* ; Penile Erection ; Plasma ; Serotonin*

No abstract available.
Meningitis, Aseptic*

Goltz syndrome is known as a rare mesoectodermal hereditary disease, characterized by focal dermal atrophies with hernias of adipose tissue and also associated with a multitude of possible skeletal, dental, ophthalmological and other abnormalities. We experienced a case of Goltz syndrome. An one day old female newborn had focal atrophic and telangiectatic skin lesions, microphthalmia, syndactyly and urinary tract abnormality. The finding of skin biopsy was consistent with focal dermal hypoplasia. We report the case with a brief review and related literatures.
Adipose Tissue ; Atrophy ; Biopsy ; Female ; Focal Dermal Hypoplasia* ; Genetic Diseases, Inborn ; Hernia ; Humans ; Infant, Newborn ; Microphthalmos ; Skin ; Syndactyly ; Urinary Tract

PURPOSE: It has been presumed that male sexual dysfunction correlates highly with psychological factors. We assessed psychological factors such as anxiety, depression, and gender role in patients of psychogenic impotence. We also evaluated the differences in serum lipid profile, norepinephrine and serotonin between the patients and age-matched control subjects. SUBJECTS AND METHODS: Twenty-five men with psychogenic impotence were enrolled in this study, and thirty patients were enrolled as the age-matched control subjects. Lipid profile and norepinephrine were measured with random blood samples. Twenty-four hour urinary 5-hydroxyindoleacetic acid (5-HIAA), a urinary metabolite of serotonin, was measured. Psychological assessment, including Minnesota Multiphasic Personality Inventory (MMPI), Beck's Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI) for anxiety, and the Bem Sexual Inventory (BSRI) for gender role, was conducted. RESULTS: There was no significant difference between the patients and control subjects I any laboratory test except low-density lipoprotein (LDL). The value of LDL wee within normal reference ranges but significantly higher in the patients (p<0.05). Scores for depression (p<0.001), psychasthenia (p<0.001), social introversion (p<0.001), schizophrenia (p<0.01), hypochondriasis (p<0.05), and hysteria (p<0.05) were significantly higher in men with sexual dysfunction than in the controls. Patients with sexual dysfunction had higher scores for state and trait anxiety, especially trait anxiety, than the control subjects (p<0.05). In BSRI, a female profile was more apparent in patients than in the control group (37% versus 14%). CONCLUSIONS: These results suggest that psychosocial factors such as stress, anxiety, and depression are highly correlates with male sexual dysfunction. These factors are poorly correlated with random norepinephrine, lipid profiles and serotonin in the patients with sexual dysfunction.
Anxiety* ; Depression* ; Erectile Dysfunction ; Female ; Gender Identity* ; Humans ; Hypochondriasis ; Hysteria ; Introversion (Psychology) ; Lipoproteins ; Male* ; MMPI ; Norepinephrine ; Psychology* ; Reference Values ; Schizophrenia ; Serotonin

Functional knee braces are commonly prescribed to support anterior cruciate ligament (ACL) reconstruction. The aim of this study was to evaluate the current literature on the use of functional knee braces of ACL with respect to biomechanical, clinical and functional outcomes. A literature search was conducted (2000 to 2017) by two independent reviewers using PubMed MEDLINE database. Articles were retrieved by an electronic search using keywords (anterior cruciate ligament, brace, and bracing) and their combinations. Current functional braces used to treat ACL injury were identified. Studies that met inclusion criteria were assessed for pertinent data. Fourteen studies met the inclusion criteria. Functional knee brace reportedly did not improve long-term clinical and functional outcomes following ACL reconstruction, but some studies suggest that functional brace may have some benefit with regard to biomechanics, proprioception, and subsequent injury rates. Functional knee brace after ACL reconstruction was found no significant difference in clinical and functional outcomes. But Further large-scale recent studies will be required to determine long-term outcomes of the brace.
Anterior Cruciate Ligament Reconstruction ; Anterior Cruciate Ligament* ; Braces* ; Knee ; Ligaments ; Proprioception

We report a case of polycythemia vera combined with coagulation disorder. The patient was 54 years old man who complained of continuous bleeding after incision of skin abscess 20days ago. Laboratory tests were revealed prolonged aPTT and slightly prolonged PT. Coagulation factor, I, VIII, IX, XI and fibrinogen decreased, however FDP did not increased. It appears that patient with polycythemia vera have chronic activation of coagulation system, probably initiated by activation of factor XII. Platelet aggregation test to ADP, collagen, epinephrine was also revealed poor response.
Abscess ; Adenosine Diphosphate ; Blood Coagulation Factors ; Collagen ; Epinephrine ; Factor XII ; Fibrinogen ; Hemorrhage ; Humans ; Platelet Aggregation ; Polycythemia Vera* ; Polycythemia* ; Skin

Cavernous lymphangioma in mediastinum is a rare congenital malformation of lymphatic system and is caused by lack of adequate drainage from the sequestrated lymphatic vessels to the venous system due to insufficiency or atresia of the efferent lymphatic channels The authors experienced 10 month-old male patient with cavernous lymphangioma in mediastinum documented by chest CT and open biopsy The review of the literature was made briefly.
Biopsy ; Drainage ; Humans ; Infant ; Lymphangioma* ; Lymphatic System ; Lymphatic Vessels ; Male ; Mediastinum* ; Tomography, X-Ray Computed

Mucocutaneous Lymph Node Syndrome(MLNS), a recently recognized entity was first reported by Dr. T. Kawasaki in Japan in 1967 and then about 12,000 cases have been reported since 1967; it is now being found in the United States, but it's etiology is still unknown. The characteristic symptoms is high fever, hypermia of conjunctivae and sclera, reddening of lips and oral cavity, palmer and solar erythema with desqumation and swelling of cervical lymph nodes. Authors insisted that this entity was quite distinct from periarteritis nodosa, Steven-Johnson syndrome, scarlet fever, erythema multiforme and in many ways. We experienced four cases of it and all cases were male and three or them were under the age of two years. All cases had the episodes of high fever, and three of them showed the characteristic symptoms of desquamation, indurtive edema and cervical lymphnodes swelling. In our cases, the fever was continued for about 13 days and desquamation appeared near the end of second weeks of illness. This disease has been treated with various antibiotics and aspirin, but the key point of treatment is how to prevent the complications. From these cases, it may be an interesting disease entity which might be evaluated by careful investigations and follow up study.
Anti-Bacterial Agents ; Aspirin ; Conjunctiva ; Edema ; Erythema ; Erythema Multiforme ; Fever ; Humans ; Japan ; Lip ; Lymph Nodes ; Male ; Mouth ; Mucocutaneous Lymph Node Syndrome* ; Polyarteritis Nodosa ; Scarlet Fever ; Sclera ; United States

Anti-leucine-rich glioma inactivated-1 (LGI1) antibody has been known as the most common antibody in autoimmune limbic encephalitis. We report a case of a 63-year-old woman who presented with repetitive memory impairment. She was diagnosed with anti-LGI1 limbic encephalitis by clinical symptoms, magnetic resonance imaging, electroencephalography, and antibody test. Hepatocellular carcinoma (HCC) was discovered incidentally. Clinical seizures were completely controlled after hepatic segmentectomy without immunotherapy. This is the first case report showing the relationship between HCC and anti-LGI1 limbic encephalitis.

Takayasu's arteritis is a chronic inflammatory disease of unknown etiology involving the thoracic and abdominal aorta and its major branches. In some cases other vessel such as renal arteries, coronary arteries, and even pulmonary arteries may be involved. Total aortography is very important, because the clinical features are determined by the extent and severity of the specific artery involved in the occlusive phase of the disease. We report a case of Takayasu's arteritis type IV in a 38 year man with pulmonary arterial involvement and pulmo-nary hypertension.
Aorta, Abdominal ; Aortography ; Arteries ; Arteritis* ; Coronary Vessels ; Hypertension ; Hypertension, Pulmonary* ; Pulmonary Artery ; Renal Artery ; Takayasu Arteritis*