2.Concentrations of welding fume by local exhaust ventilation.
Sung Ki PARK ; Kyeong Dong CHUNG ; Doo Hie KIM
Korean Journal of Occupational and Environmental Medicine 1993;5(1):163-170
No abstract available.
Ventilation*
;
Welding*
4.Brain MRI Findings for the Patient with the Late Onset Schizophrenia: Comparison among Patients with the Early Onset Schizophrenia, Progressive Schizophrenia, Senile Dementia and Controls.
Doo Sung PARK ; Young Ho LEE ; Young Hee CHOI ; Young Soo PARK ; Young Cho CHUNG
Journal of the Korean Society of Biological Psychiatry 1997;4(1):74-83
With increasing tendency of incidence and interest for the late onset schzophrenia, concerns about whether this disorder is etiologically or phenomenogically distinctive entity or not have increased also. To clarify the disease entity of the late onset schzophrenia and the role of structural brain changes in its etiology, authors tried to prove following hypothesis : Are there any evidences of structural brain changes in the late-onset schizophrenia? ; If present, are they not different from those of the early-onset schizophrenia or progressive schizophrenia? ; And are they not different from those of senile dementia? Subjects were 6 patients with the late-onset schizophrenia, 6 patients with the early-onset schizophrenia, 6 patients with progressive schizophrenia, 6 patients with Alzheimer's dementia, and 6 controls. We measured regions of interest of the magnetic resonance images by computer assisted planimetry using the AutoCad and digitizer. Our study results may suggest that the third ventricular enlargement and a reversal of normal difference between left and right temporal lobe and left-right difference in posterior lateral ventricle are common brain pathology for all type of schizophrenia including the late onset schzophrenia. And also suggest that brain structural changes of the late onset schizophrenia are related with neurodevelopmental abnormality rather than degenerative change.
Alzheimer Disease*
;
Brain Diseases
;
Brain*
;
Dementia
;
Humans
;
Incidence
;
Lateral Ventricles
;
Magnetic Resonance Imaging*
;
Schizophrenia*
;
Temporal Lobe
5.In Vitro Tissue Engineering of Cartilage using Autologous Fibrin Glue and Chondrocytes.
Sung Pyo HONG ; Jin Sik BURM ; Jae Kyung PARK ; Jin Young KIM ; Doo Hyung LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(3):383-391
Neomorphogenesis of cartilage using chondrocyte-polymer constructs is a potential source for development of cartilage reconstruction. Current tissue engineering techniques of neocartilage rely on in vivo implantation of polymer-chondrocyte constructs. The purpose of this study was to find a way to bioengineer cartilage in vitro by entrapping chondrocytes in a molded autologous fibrin glue. Chondrocytes isolated from the cartilage of rabbit joints were combined with fibrinogen extracted by a single cryoprecipitation of autologous plasma, and they were then polymerized with thrombin to create a fibrin glue with a final cell density of 2.5x10(6) cells/ml. The collagen for a control study was used as a polymer. The polymer-chondrocyte constructs were cultured for 4 weeks and the fibrin-chondrocyte constructs molded in the shape of a human ear were cultured for 6 weeks in vitro. Morphometric, histochemical, and histomorphometric analysis including glycosaminoglycan quantitation confirmed the following results: 1) Highly-concentrated autologous fibrinogen was easily extracted by a single cryoprecipition of autologous olasma. 2) The fibrin-chondrocyte constructs demonstrated the presence of actively proliferating chondrocytes with the production of cartilaginous matrix(collagen and glycosaminoglycan) at 1 week after culture, as well as gross and histologic evidence similar to those of normal cartilage at 3-4 weeks after culture. 3) The collagen-chondrocyte constructs demonstrated lower degrees of hardness and transparency, as well as a lower density of cells and glycosaminoglycan during the culture period. 4) Neocartilage generated from fibrin-chondrocyte constructs in the shape of a human ear nearly retained their original configuration and size without degeneration for 6 weeks of culture in vitro. This study demonstrated a novel method for bioengineering the molded cartilage in vitro using autologous fibrin glue as a matrix scaffold. The generated cartilage showed gross and histologic evidence similar to those of normal cartilage, retaining the original gross dimension. With further refinement, this may be a new application of tissue engineering for the reconstruction of cartilage.
Bioengineering
;
Cartilage*
;
Cell Count
;
Chondrocytes*
;
Collagen
;
Ear
;
Fibrin Tissue Adhesive*
;
Fibrin*
;
Fibrinogen
;
Fungi
;
Hardness
;
Humans
;
Joints
;
Plasma
;
Polymers
;
Thrombin
;
Tissue Engineering*
6.Stevens-Johnson Syndrome Associated with Toxic Hepatitis.
Doo Han KIM ; Jung Bock LEE ; Yoon Kee PARK ; Sung Nack LEE
Korean Journal of Dermatology 1977;15(2):205-209
Pseudoxanthoma. elasticum is a rare, heritable, systemic disease of connective tissue characterized by degeneration of elastic tissue and mainly affecting the skin, eyes and blood vessels. Recently, according to Pope (1974), it can be inherited as an autosomal dominant or recessive trait. We presented a study of 5 cases of pseudoxanthoma elasticum of autosomal recessive inheritance, which showed typical peau d'orange skin lesions. Two among the 5 cases were associated with angioid streaks, a case with myopia and broderline mental retardation, and 2 cases without any other systemic disturbances.
Angioid Streaks
;
Blood Vessels
;
Connective Tissue
;
Drug-Induced Liver Injury*
;
Elastic Tissue
;
Intellectual Disability
;
Myopia
;
Pseudoxanthoma Elasticum
;
Skin
;
Stevens-Johnson Syndrome*
;
Wills
7.Pseudozanthoma Elasticum: Report of 5 Case.
Doo Han KIM ; Yoon Kee PARK ; Jung Bock LEE ; Sung Nack LEE
Korean Journal of Dermatology 1977;15(2):197-203
Pseudoxanthoma. elasticum is a rare, heritable, systemic disease of connective tissue characterized by degeneration of elastic tissue and mainly affecting the skin, eyes and blood vessels. Recently, according to Pope (1974), it can be inherited as an autosomal dominant or recessive trait. We presented a study of 5 cases of pseudoxanthoma elasticum of autosomal recessive inheritance, which showed typical peau d'orange skin lesions. Two among the 5 cases were associated with angioid streaks, a case with myopia and broderline mental retardation, and 2 cases without any other systemic disturbances.
Angioid Streaks
;
Blood Vessels
;
Connective Tissue
;
Elastic Tissue
;
Intellectual Disability
;
Myopia
;
Pseudoxanthoma Elasticum
;
Skin
;
Wills
8.An experimental study of epidermal separation by dispase under negative pressure.
Kyung No LEE ; Sung Pyo HONG ; Choong Hyun CHANG ; Doo Hyung LEE ; Jai Kyung PARK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(1):33-38
No abstract available.
9.Intestinal parasite survey of Kyungpook National University Hospital patients.
Dong Wik CHOI ; Sung Deok PARK ; Jae Woun KIM ; Doo Hong AHN ; Young Myung KIM
The Korean Journal of Parasitology 1971;9(2):47-53
For seven years from 1962 to 1968, fecal specimens of the patients were examined not only for the discovery of intestinal protozoa and helminths, but also to provie data on the incidence of intestinal parasites among the residents of Kyungpook Province, Korea. The Formalin-ether sedimentation, Lugol solution, and Heidenhain's iron-hematoxylin stained films were prepared for the recovery of intestinal parasites. Of 2,414 samples of feces examined, 35.7 percent were found to be infected with one or more species of protozoa. Among six species of protozoa detected, Entamoeba coli was observed most frequently(15.3%) followed by Entamoeba histolytica (11.9%), and then the Enteromonas hominis least often(1 case). For the survey of helminth, of a total of 5,288 fecal specimens examined, 86.7 percent were positive for one or more species of helminths. Trichocephalus trichiurus revealed the highest infection rate (83.6%), while Trichostrongylus orientalis was next (61.6%), and Ascaris lumbricoides was unexpectedly low(40.9%). The incidence for hookworm and Clonorchis sinensis was 22.4 percent and 29.8 percent respectively. Triple infections were found more frequently than double infections, and mixed infections of six or more species of helminths were observed in 3.8 percent of specimens.
parasitology-helminth-protozoa-nematoda-cestoda-trematoda
;
Entamoeba coli
;
Entamoeba histolytica
;
Enteromonas hominis
;
Endolimax nana
;
Iodamoeba butschlii
;
Giardia lamblia
;
Trichocephalus trichiurus
;
Trichostrongylus orientalis
;
Ascaris lumbricoides
;
hookworm
;
Clonorchis sinensis
;
Enterobius vermicularis
;
Paragonimus westermani
;
Metagonimus yokogawai
;
Taenia species
;
epidemiology
;
stool examination
;
Formalin-ether
;
sedimentation
;
Lugol solution
;
Heidenhain's iron-hematoxylin
10.Congenital bile duct cyst.
Myung Hee YOON ; Mi Sung JEONG ; Hyung Ja PARK ; Shinna KIM ; Doo Sun LEE
Journal of the Korean Pediatric Society 1991;34(5):707-714
No abstract available.
Bile Ducts*
;
Bile*
;
Choledochal Cyst*