1.The impact of body mass index changes on traumatic brain injury patients’ outcomes during hospitalization
Bahram AMINMANSOUR ; Soroush SAMERI ; Mehdi SHAFIEI ; Mehdi MAHMOODKHANI ; Donya Tehrani SHEIBANI
Chinese Journal of Traumatology 2024;27(6):323-327
Purpose::Obesity is a complex multifactorial disease with increasing prevalence worldwide. The present study was conducted, since there were different results on the effect of obesity on the prognosis of patients with moderate and severe brain trauma, and the issue was less investigated.Methods::The present descriptive-analytical study was conducted in 2 hospitals, Al-Zahra and Kashani in year 2022. Patients with Glasgow coma scale (GCS) score of 9 -12 (moderate concussion) and patients with a GCS score of < 8 (severe concussion) who consented to participate in the study were included in the study. Patients who died; had serious injuries related to the chest, abdomen, pelvis, spine, and organs, in addition to the concussion; had a part of their body amputated during the same incident; received medications; or had diseases which caused obesity like diabetes were excluded from the study. Patients’ height and weight were extracted for calculating the body mass index (BMI). Their functional independences were measured at admission and discharge according to the Glasgow outcome scaleextended (GOSE) scale. All the data were analyzed in SPSS 26.Results::This study examined a total of 287 traumatic brain injury (TBI) patients (251 with moderate concussion and 36 with severe concussion). In total, 91 (36.3%) patients with moderate TBI had a lower BMI, and 14 (38.9%) patients with severe TBI had a constant BMI. There was a significant difference between the mean changes of BMI and the GOSE, functional independence measure (FIM) motor ( p =0.006), FIM cognitive ( p =0.023), and FIM total scores ( p =0.002) in patients with severe TBI; however, significant difference was found only between the mean changes of BMI, GOSE and FIM motor scores ( p=0.001) in patients with moderate TBI. Conclusion::BMI is a risk factor affecting treatment results in patients with TBI, which should be controlled.
2.Patients With Hemangioblastoma: Mood Disorders and Sleep Quality
Ali RIAZI ; Yaser EMAEILLOU ; Nima NAJAFI ; Mohammad HOSEINIMANESH ; Mohammad Ibrahim ASHKARAN ; Donya Sheibani TEHRANI
Brain Tumor Research and Treatment 2024;12(2):87-92
Background:
Sleep has confirmed physical, psychological, and behavioral benefits, and disruptions can result in disturbances in these states. Moreover, it can be linked bidirectionally with susceptibility to and the subsequent status of brain tumors. The current study examined mood disorders and sleep quality before and after surgery for hemangioblastoma brain tumors.
Methods:
Thirty-two patients diagnosed with hemangioblastoma brain tumors between 2017and 2023 underwent surgical treatment. The Karnofsky Performance Status and ECOG performance status scales, the Brunel Mood Scale, the Morningness-Eveningness Questionnaire, and the MiniSleep Questionnaire were employed to assess the patients.
Results:
The findings indicate that after surgery, sleep quality and mood disorders, including tension, vigor, and depression, did not exhibit significant differences in these patients (p>0.05). However, tension, vigor, depression, and sleep quality did have a significant impact on their functional status post-surgery (p<0.05).
Conclusion
Depression is the significant mood factor in patients with brain tumors that impact their functional status. In this context, it is recommended that psychological therapies be considered for them, alongside conducting more comprehensive and in-depth studies on psychological disorders in patients with brain tumors.
3.Authors’ Reply to Letter to the Editor: Commentary on In-Fracture Pedicular Screw Placement During Ligamentotaxis Following Traumatic Spine Injuries, a Randomized Clinical Trial on Outcomes (Korean J Neurotrauma 2023;19:90–102)
Arman SOURANI ; Majid REZVANI ; Jamalodin ASADI ; Mina FOROUGHI ; Donya Sheibani TEHRANI
Korean Journal of Neurotrauma 2023;19(4):509-510
4.Basilar Skull Fractures and Their Complications in Patients With Traumatic Brain Injury
Mehdi SHAFIEI ; Bahram AMINMANSOUR ; Mehdi MAHMOODKHANI ; Mohammadamin SEYEDMOALEMI ; Donya Sheibani T TEHRANI
Korean Journal of Neurotrauma 2023;19(1):63-69
Objective:
Since traumatic brain injury is more common in young people, who are the main workforce and builders of society, it is important to consider the effects caused by brain injury on them. In this study, we investigated the clinical manifestations, complications, and prognosis of patients with basilar skull fractures.
Methods:
This cross-sectional study was conducted from March 2021 to March 2022 at the Kashani Hospital, Esfahan, Iran. Patients with basilar skull fractures were included in this study by census for one year. Recorded patient information was divided into two parts:demographic information, including age and sex, and disease information including loss of consciousness, signs of meningitis, need for surgery, and neurologic examination.
Results:
In this study, 100 patients were included, of whom 89 were men. The most common complication was pain at the site of the trauma, followed by bruising and bleeding from the site of the trauma. Raccoon eyes and cerebrospinal fluid leakage were observed in 19% and 32% of the patients, respectively.
Conclusion
As the occurrence of trauma has an economic burden on the country's health system, we must identify its consequences and problems and prevent its occurrence as much as possible by implementing educational measures.
5.In-Fracture Pedicular Screw Placement During Ligamentotaxis Following Traumatic Spine Injuries, a Randomized Clinical Trial on Outcomes
Majid REZVANI ; Jamalodin ASADI ; Arman SOURANI ; Mina FOROUGHI ; Donya Sheibani TEHRANI
Korean Journal of Neurotrauma 2023;19(1):90-102
Objective:
To investigate the efficacy and safety of two different techniques for spinal ligamentotaxis. Spine ligamentotaxis reduces the number of retropulsed bone fragments in the fractured vertebrae. Two different ligamentotaxis techniques require clinical evaluation.
Methods:
This was a randomized clinical trial. The case group was defined as one pedicular screw insertion into a fractured vertebra, and the control group as a no-pedicular screw in the index vertebra. Spine biomechanical values were defined as primary outcomes and complications as secondary outcomes.
Results:
A total of 105 patients were enrolled; 23 were excluded for multiple reasons, and the remaining were randomly allocated into the case (n=40) and control (n=42) groups. The patients were followed up and analyzed (n=56). The postoperative mid-sagittal diameter of the vertebral canal (MSD), kyphotic deformity correction, and restoration of the anterior height of the fractured vertebrae showed equal results in both groups. Postoperative retropulsion percentage and pain were significantly lower in the case group than in the control group (p=0.003 and p=0.004, respectively). There were no group preferences for early or long-term postoperative complications.
Conclusions
Regarding clinical and imaging properties, inserting one extra pedicular screw in a fractured vertebra during ligamentotaxis results in better retropulsion reduction and lower postoperative pain.
6.Half-Saline Versus Normal-Saline as Irrigation Solutions in Burr Hole Craniostomy to Treat Chronic Subdural Hematomata: A Randomized Clinical Trial
Mehdi MAHMOODKHANI ; Mohammad SHARAFI ; Arman SOURANI ; Donya Sheibani TEHRANI
Korean Journal of Neurotrauma 2022;18(2):221-229
Objective:
This study aimed to evaluate the efficacy and safety of half-saline (HS) serum as an irrigation solution in chronic subdural hematoma (CSDH) surgery using the burr hole craniostomy (BHC) technique.
Methods:
This randomized clinical trial was conducted in university hospital referral centers from 2020 to 2021. Sixty-three patients with CSDH eligible for BHC were primarily enrolled. Two patients were excluded because of concurrent stroke. Sixty-one patients were randomly allocated into case (HS=30) and control (normal-saline [NS]=31) groups. HS was used to irrigate the hematoma in the case group and NS was used in the control group. The patients were followed-up. Clinical variables including demographic and medical findings, postoperative computed tomography findings, postoperative complications, hospitalization period, recurrence rate, and functional status measured by the Barthel type B index were recorded.
Results:
Forty-six of 61 patients were male (75.4%), and the patients’ mean age was 65.4±16.9 years, with equal distribution between the 2 groups. Postoperative effusion and postoperative hospital stay duration were significantly lower in the HS group than in the NS group (p=0.002 and 0.033, respectively). The postoperative recurrence within 3 months in both groups was approximately equal (6.6%). In terms of functional outcomes and postoperative complications, HS showed similar results to those of NS.
Conclusion
HS as an irrigation fluid in BHC effectively reduced postoperative effusion and hospital stay duration without considerable complications.