1. Study on periodontal status of patients with pre-diabetes
Dongsiqi JIN ; Yanting LIAO ; Lu HE ; Huanxin MENG ; Peng LI
Chinese Journal of Stomatology 2019;54(3):157-163
Objective:
To investigate periodontal status of patients with pre-diabetes and evaluate the prevalence of periodontal pathogens in oral cavity.
Methods:
All the subjects were under regular care in urban area of Beijing, including 88 subjects with normal blood glucose (normal blood glucose group), 27 pre-diabetic patients (pre-diabetic group), 58 well-controlled diabetic patients (glucose well controlled group) and 72 poor-controlled diabetic patients (glucose poor controlled group). Whole unstimulated saliva samples were collected before periodontal examination. Periodontal parameters, including plaque index (PLI), probing depth (PD), bleeding index (BI), bleeding on probing (BOP) and clinical attachment loss (CAL), were examined at mesial-buccal and distal-lingual sites of each tooth. Number of missing teeth was recorded. DNA was extracted from the salivary deposition,
2. Preliminary study of subgingival microorganism changes after glycine powder air-polishing treatment during periodontal maintenance phase
Yibing ZHAO ; Dongsiqi JIN ; Lu HE ; Huanxin MENG
Chinese Journal of Stomatology 2017;52(7):410-414
Objective:
To research the variation of subgingival microorganisms after 65 μm glycine powder air-polishing (GPAP) in patients with periodontitis during periodontal maintenance phase and make comparison with conventional method.
Methods:
From Department of Periodontology, Peking University School and Hospital of Stomatology, twenty-one patients at the age of 35-72 (8 males and 13 females) who were systematically healthy were recruited in this study. According to splitting-mouth design, one side of a mouth was randomly assigned to the experiment group (21 patients, 248 teeth, 1 488 sites) with 65 μm GPAP therapy while the opposite side served as the control group (21 patients, 249 teeth, 1 494 sites) with ultrasonic scaling plus polishing paste therapy. The clinical periodontal parameters including probing depth (PD), bleeding index (BI), bleeding on probing (BOP) and plaque index (PLI) were recorded. Using sterile currette, the subgingival plaque samples were collected at the mesio-buccal site of the first or second molars at baseline, 2, 4, 8 and 12 weeks after therapy, respectively. After Congo red staining, the microorganisms were classified into cocci, bacilli and spirochetes and counted respectively.
Results:
All clinical periodontal parameters have no difference between two groups at baseline and after treatment 12 weeks. In the experiment group and the control group, PD ([2.33±0.90] and [2.37±1.18] mm), BI (0.96±0.70 and 0.98±0.78) and PLI (0.00[1.00] and 0.00[1.00]) of two groups after treatment 12 weeks were better than those at baseline (PD: [2.48±1.17] and [2.46±0.99] mm; BI: 1.07±0.72 and 1.08±0.75; PLI: 0.00 [1.00] and 0.00 [1.00]) (