Objective To evaluate the clinical value of high-frequency color doppler ultrasound in diagnosis of common carotid artery vasculopathy of diabetes mellitus. Methods High-frequency color doppler ultrasound was used to detect the intima-media thickness (IMT), inner diameter(CCAD), resistent index (RI) and atherosclerotic plaque of common carotid artery in 40 patients with diabetes, and then compared with 35 normal cases. Results IMT,CCAD and RI as well as incidence of atherosclerotic plaque of common carotid artery in diabetics were signifi-cantly higher than that in the control group(P < 0.05). Conclusion High-frequency color doppler ultrasound can di-rectly show the degree of carotid lesion and atherosclerotic plaque, and is of practical value and a guide in diagnosing atherosclerosis and preventing brain embolism in diabetics.

Objective To compare the efficacy of ultrasound -guided percutaneous catheter drainage and incision and drainage catheter in treatment of liver abscess.Methods 50 cases with liver abscess who had given ultrasound -guided percutaneous catheter drainage as the observation group were randomly selected and 50 cases with liver abscess who had given open catheter drainage over the same period were selected as the control group.The cure rate,white blood cell count(WBC),body temperature returned to normal,extubation time,hospitalization and the occurrence of complications of two groups were compared.Results (1)The WBC,body temperature returned to nor-mal,extubation time,hospitalization of the observation group were (4.35 ±1.45 )d,(3.68 ±1.68)d,(10.85 ± 1.66)d,(13.76 ±2.80)d,which were significantly shorter than (7.66 ±2.83)d,(6.22 ±2.75 )d,(13.05 ± 1.95)d,(17.96 ±2.91 )d of the control group.The difference between the two groups had statistically significant (t1 =8.352,t2 =9.145,t3 =7.552,t4 =8.443,all P <0.05);(2)One case of postoperative wound infection of the observation group,the complication rate was 2%,two cases of postoperative wound infection of the control group,one case of empyema,two cases of bleeding,the incidence was 10%,the difference in the incidence of complications between the two groups were statistically significant(χ2 =6.73,P <0.05).Conclusion Ultrasound -guided percu-taneous catheter drainage was trauma,quick recovery,safer,which is worthy of clinical application.

Objective To compare the value of hardness rating and area ratio method of ultrasound elastog-raphy in differential diagnosis of benign and malignant lesions.Methods ultrasound imaging data of 120 cases with breast lesions(130 breast)who were pathologically confirmed during the period from January 201 1 to June 2013 were retrospectively analyzed,there were 62 malignant tumors,68 benign tumors,the sensitivity,specificity,accuracy of hardness rating and area ratio method of ultrasound elastography in differential diagnosis of benign and malignant lesions were assessed.Results (1 )The ultrasound elastography of 52 cases with benign tumor were 0 -2point, 16 cases were 3-4point,10 cases with malignant tumors were 0 -2point,52 cases were 3 -4point,the difference between two groups were statistically significant(χ2 =11.55,P<0.05);(2)The average area ratio of benign tumor was (1.09 ±0.37),malignant tumors was (2.28 ±1.68),the difference between two groups were statistically signifi-cant(t =6.22,P=0.01);(3)the sensitivity,specificity,accuracy of elastography hardness rating in diagnosis of malignant breast tumors were 83.87%,6.47%,80.00%,the area ratio method were 80.65%,75.00%,77.68%, joint inspection of two groups were 93.10%,93.55%,93.09%,joint inspection had obvious advantages,the differ-ence was statistically significant(all P<0.05 ).Conclusion Hardness rating and area ratio method of ultrasound elastography in differential diagnosis of benign and malignant lesions had higher value and higher diagnostic accuracy of combined.

Objective To investigate the effect and mechanism of ganoderma acid in therapy of the rat essential hypertension.Methods 30 male spontaneously hypertensive rat (SHR) were divided randomly into three groups:control group (CG),ganoderma acid group (Gan) and captoril (Cap) as positive control group.SHR were fed with distilled water (10 ml/kg) in control group,ganoderma acid (0.6 g/kg ) in Gan group,catopril (0.03 g/kg) in Cap group.After 8-weeks therapy,5 ml blood was extracted,rats in every group were sacrificed to get the aorta.The mRNA expression of superoxide dismutase (SOD),nitric oxide synthase (NOS) and high density lipoprotein (HDL) were detected by RT-PCR and the apoptosis of endothelial cells were measured by flowcytometry.Results After the 8 weeks therapy,as compared with the CG group,blood pressure of SHR in Gan group became stable[(112.6±3.2) mm Hg](P＜0.01).The expression of SOD,NOS and HDL showed obviously upregulated,and apoptosis of endothelial cell decreased significantly (P＜0.01).NO contents increased,and MDA,ET-1 decreased (P＜0.01).The contents of LDL decreased and HDL increased (P＜0.01).Conclusions Ganoderma acid may improve the function of endothelial cell and decrease the blood pressure by promoting the mRNA expression and activity of SOD,cleaning the radical ions and inhibiting the apoptosis of the endothelial cell.

In order to collect infection surveillance data from hospital to unfold scientific research, infection surveillance information platform based on B/S structure is designed adapting with the object - based technology. The general structures, the possibility of tech-nology realization, function installation and major process of finishing a mission are explained in detail in the paper. Using this platform could not only realize the data sharing between researchers and clinicians but also promote the prevention and control of infection in hospital.

Objective To analyze the requirements of the Chinese PLA biosecurity and disease prevention and to develop an Internet information tracking system for infectious disease surveillance .Methods A focused crawler was used to automatically collect Internet information about infectious diseases before the information could be released , automatically correlated and analyzed .Results This system could claw the Internet information of infectious disease surveillance and build an infectious disease surveillance information knowledge database .Conclusion The use of this system can not only improve the efficiency of information studies , but also meet the information requirements of infectious disease prevention in Chinese PLA.

Objective By developing ultrasound picture archiving and communication system(PACS),to implement networking of ultrasound imaging equipment, central image storage and standardization of computer-aided diagnosis report.Methods Ultrasound image workstation was develop to acquire, display, manipulate and print ultrasound static and dynamic images using C++ computer language. Also, all ultrasound equipments in department formed the DICOM network . Central image server and ultrasound information system server we re connected together with all workstations by computer Ethernet network, thus, using switch, and connecting to hospital internet WWW server to distribut the image and report. Results Ultrasound DICOM digital images and high quality video image successfully acquired, displayed, processed and network communicated, seamless integrated with hospital information system, functions such as image central storage, computer-aided report and sharing printing were implemented. Conclusions Application of ultrasound image management system improves the administration and increases work efficiency in imaging diagnosis, promotes the reform of working pattern of doctors and provides more convenience for work, research and study. Image systems highly increase the level of patient care service. Standardization of medical reports computer-aided is superior to handwritten report.

ObjectiveTo investigate the characteristics of three vaginal bacteria inspection methods of Amsel method,gram staining Nugent score method and bacterial vaginosis (BV) Blue methodMethods The leucorrhea specimen of 99 vaginal fluid abnormal patients were examined by Amsel method,gram staining Nugent score method and BV Blue method,then compared and analyzedResultsThe positive rate was 28.28％ (28/99) in Amsel method,47.47％(47/99) in gram staining Nugent score method and 16.16％ (16/99) in BV Blue method.There were significant differences among three methods(P＜ 0.01 ).The specificity and sensitivity of gram staining Nugent score method was higher.ConclusionThe three vaginal bacteria inspection methods have advantage and shortcoming individually,suspecting patients should be followed up to detect and diagnose in chnic,or detected by many methods.The specificity and sensitivity of gram staining Nugent score method is higher,but BV Blue method is simple,faster,which has higher value in detection and diagnosis in BV.

To investigate the pathological changes in gunshot wound track in limbs of dogs produced under a hot and humid environment, 8 dogs were randomly divided into two groups: hot and humid environment group (HHE) and normal environment group(NE). Gross examination, optical microscopic examination (OM), electron microscopic examination (EM) were performed, and ATP, ADP, AMP content, energy charge (EC) in the gunshot wounds were observed at 4, 8, 12, 24h after wounding. The results indicated that 6～8 h after the injury, the wound tracks and discolored area of tissue in HHE group were more distinguished and enlarged than those in NE group, and the swelling of wounded limbs was obvious. Some of the wounds began to be odoriferous. The signs of infection began to be obvious. While the wounds of NE group did not give off obvious odor of decay until 12～24h after the injury. Under OM and EM, necrosis and damage of muscle fibers in the wound tracts were more obvious in the HHE group than that in NE group, showing a tendency of deterioration. In contrast the changes in the injured tissues in NE group showed a tendency of improving. ATP content of the injured tissues in the contusion region of HHE group was lower than that of NE group at 8h, ATP content of tissues in the shock region of HHE group was decreased continuously and was lower than that of NE group at 12h. ADP content of tissues in the contusion area of HHE group was lower than that of NE group at 8h and also in shock area at 12h. AMP content of tissues in the contusion area of HHE group was higher than that of NE group at 12h, whereas EC of tissues in the contusion area of HHE group was lower than that of NE group at 8h and 12h. Histopathological changes in tissues in the gunshot wound were serious and deteriorated gradually in hot and humid environment. At the same time the energy storage of muscle tissue in the gunshot wound track was lower and decreased more remarkably in this environment. Therefore early and complete debridement of gunshot wounds inflicted in hot and humid environment should be emphasized.

Objective To discuss the relationship of metabolizing enzyme Cystathionine βsynthase (CBS) G919A gene polymorphism with essential hypertension on Hui nationality in Xinjiang. Methods Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to detect the gene polymorphism, blood lipid, blood sugar and other biochemical indicators were tested at the same time. Result The distribution frequency of genotype GG, GA, AA and A,G, of CBS G919A was 76.4%, 19.0%, 4.5%, which was of no significant difference compared with the control group (P > 0.05). Conclusion Gene polymorphism of CBS G919A was existed, which was no relationship with essential hypertension on Hui nationality in Xinjiang.