The aim of this review is to realize the significance of physical activity for colorectal cancer survivors, collect the common tools to assess colorectal cancer patients' physical activity, understand the current status and its influencing factors of colorectal cancer patients' physical activity as a reference to Chinese relevant research and provide a basis for carrying out medical or nursing intervention.

AIM: To explore the significance of platelet activation, fibrinolytic activity and the changes of vasoactive mediators in acute myocardial infarction in rabbits and the intervention of amiodarone and metoprolol. METHODS: Fifty New Zealand white rabbits were randomly assigned to five groups, ten for each. Group Ⅰ: sham group, group Ⅱ: acute myocardial infarction(AMI) group, group Ⅲ: AMI and lidocaine group, group Ⅳ: AMI and amiodarone group, group Ⅴ: AMI and metoprolol group.The middle point of left ventricular coronary artery was ligated (groupⅡ,Ⅲ, Ⅳ and Ⅴ ) or a sham ligation(group Ⅰ). Four hours later, blood was collected for measuring plasma concentration of TXB 2, 6-Keto-PGF 1?, ET, NO, plasma activity of t-Pa and PAI.After that, the heart was taken out to evaluate the infarction size(IS). RESULTS: Plasma concentration of TXB 2, ET, NO and plasma activity of PAI were significantly higher in groupⅡ,Ⅲ, Ⅳ and Ⅴ than those in group Ⅰ(P0.05).Compared to group Ⅱ, plasma concentration of ET, NO and PAI activity were significantly decresed (P

To analyze colostomy patients′bowel function assessment tools and application status by describing the bowel function characteristics of colostomy patients and making a summary of colostomy patients ′bowel function through the literature research .The purpose of this article is to provide the reference for measurement of colostomy patients by thinking the application problems of bowel function assessment tools .

Objective To analyze and provide reference for developing clinical practice guidelines of ostomy care suitable for the domestic health care settings. Methods Content analysis method was used to analyze clinical practice guidelines searched from the Internet. Results A total of 13 clinical practice guidelines were included. All the guidelines were published between 2005 to 2016 without update. Four of them were evidence-based guidelines, the rest were not. A total of 21 items were identified as being related to ostomy care. Conclusions Although the existing clinical practical guidelines are instrumental to guiding clinical ostomy care practice, most of them were not evidence-based guidelines without high methodological quality. Meanwhile, some guidelines lack specific and updating recommendations for ostomy care, which may cause problems in ostomy care practice. What′s more, some recommendations may not suit for China because they were made in the foreign circumstance. Researchers and clinical nurses should develop local practice guidelines of ostomy care with consideration of the actual medical conditions in China and the best evidence.

Objective:To explore the current situation of eHealth literacy of tumor patients and to analyze its influencing factors so as to provide a reference for clinical promotion measures of eHealth literacy.Methods:From November 2019 to January 2020, 132 tumor patients in a ClassⅢGrade A cancer hospital were selected by convenience sampling. Patients were investigated with the Chinese version of the eHealth Literacy Scale (eHEALS) and self-designed General Information Questionnaire. Single factor analysis and multiple stepwise regression were used to analyze the influencing factors of eHealth literacy of tumor patients.Results:The total score of eHealth literacy of tumor patients was (24.21±9.07) . Regression analysis showed that the main influencing factors of eHealth literacy of tumor patients included the age, domicile place, number of internet tools, number of channels for obtaining health information, discussion with family members about using internet to find health resources ( F=28.020, P<0.001) . Conclusions:Tumor patients have low levels of eHealth literacy. We should pay attention to the elderly, rural residents, people who lack internet access tools and lack access to health information. When conducting eHealth education, the health education needs of this group of people cannot be ignored. Discussion with family members about using the internet to find health resources may improve eHealth literacy of tumor patients. We can fully mobilize the support of family members when carrying out eHealth literacy promotion program.

Objective:To evaluate the quality of domestic and foreign hospice care practice guidelines for cancer patients, so as to provide a basis for the future development of scientific and systematic hospice care guidelines for cancer patients or the formulation of evidence-based nursing practice plans for hospice care of cancer patients in China.Methods:Practice guidelines on hospice care for cancer patients were systematically retrieved from domestic and foreign databases, guidelines and professional society websites from the establishment of the database to July 25, 2020. Two investigators screened the guidelines strictly according to the inclusion and exclusion criteria, and evaluated the methodological quality of the included guidelines by using the currently internationally recognized guideline evaluation tool, the Appraisal of Guidelines for Research and Evaluation version Ⅱ (AGREE Ⅱ) .Results:A total of 14 guidelines were included for quality analysis, 9 guidelines were Grade A, 1 guidelines was Grade B, and 4 guidelines were Grade C. The average standardized scores of the 6 areas in AGREEⅡ of the 14 guidelines from high to low were scope and purpose (91.87%) , clarity (83.73%) , stakeholder (72.82%) , applicability (66.81%) , rigor (63.84%) and independence (58.04%) . The subject content analysis of 9 Grade A guidelines showed that common topics in the practice guidelines for hospice care of cancer patients included forming interdisciplinary teams, identification of end-of-life patients, assessment of end-of-life needs, end-of-life communication, providing of individualized nursing, end-of-life symptom management, bereavement support, support and training for nurses.Conclusions:Evidence-based guidelines for hospice care of cancer patients are lacking in China. The existing practice guidelines for hospice care of cancer patients in foreign countries are of high quality and cover a comprehensive range of topics, which can provide a reference for our country to formulate hospice care guidelines in line with national conditions or to transform the best evidence into our country's hospice care practice.

Objective:To construct advanced practice competencies for nurses in tumor prevention and early screening and promote nurses' professional role in cancer prevention and treatment.Methods:A literature review was conducted to draft advanced nursing practice competencies in tumor prevention and early screening. A first-round expert consultation questionnaire was developed, followed by two rounds of Delphi expert consultations involving 25 experts from 10 hospitals and institutions nationwide engaged in clinical nursing, nursing management, clinical medicine, genetics, and epidemiological research in tumor prevention and screening.Results:Advanced practice competencies for nurses in tumor prevention and early screening were formulated around seven aspects: communication, health promotion and education counseling, clinical practice, professional development, ethical decision-making, evidence-based practice and research, and leadership.Conclusions:Core competencies necessary for nurses to engage in advanced practice in tumor prevention and early screening were established, thus providing a basis for enhancing their role in cancer care.

With the continuous development of health care, people's awareness of health care is gradually enhanced. Pain has become an important part of disease rehabilitation and nursing. The research and evidence of pain assessment and management are increasing year by year. As the most direct assessor and manager of patients' pain, it is particularly important for nurses to identify and effectively manage different types of pain as soon as possible. In this background, the Registered Nurses' Association of Ontario (RNAO) released Clinical Best Practice Guidelines:Assessment and Management of Pain(Third Edition)in 2013. This article mainly introduces the development, application scope, methodology, main content, quality evaluation and subsidiary information of the guide.