1.Investigation on flavonoids from fruits of Illicium oligandrum
Wenzhao TANG ; Dongmin SU ; Shishan YU ; Jing LIU ; Jing QU ; Yunbao LIU
Chinese Traditional and Herbal Drugs 1994;0(10):-
Objective To isolate and identify the flavonoids from the fruits of Illicium oligandrum.Methods The flavonoids were isolated by silica-gel,Sephadex LH-20,and ODS column chromato-graphies.Their structures were elucidated by 1H-NMR,13CNMR,and ESI-MS.Results Eleven flavonoids were isolated and identified as kaempferol(Ⅰ),quercetin(Ⅱ),quercetin-3-O-?-D-galactopyranoside(Ⅲ),isorhamnetin-3-O-?-D-glucopyranoside(Ⅳ),quercetin-3-O-?-L-arabinopy-ranoside(Ⅴ),quercetin-3O-?-L-rhamnopyranoside(Ⅵ),dihydroquercetin-3O-?-L-rhamnopyranoside(Ⅶ),dihydrokaempferol-3O-?-L-rhamnopyranoside(Ⅷ),quercetin-3O-?-D-(6″-O-?-L-rhamnopy-ranosyl) glucopyranoside(Ⅸ),kaempferol-3-O-?-D-(6″-O-?-L-rhamnopyranosyl) glucopyranoside(Ⅹ),isorhamnetin-3-O-?D-(6″-O-?-L-rhamnopyranosyl) glucopyranoside(Ⅺ).Conclusion All these compounds are firstly obtained from the plants of fruits of I.oligandrum and compounds Ⅳ,Ⅴ,Ⅶ,Ⅷ,and Ⅺ are isolated from the plants of Illicium L.for the first time.
2.Diagnostic accuracy of urine dipstick for proteinuria in older outpatients.
Dongmin LIM ; Dong Young LEE ; Soung Ha CHO ; One Zoong KIM ; Sang Woo CHO ; Su Kyoung AN ; Hwe Won KIM ; Kyoung Hyoub MOON ; Myung Hee LEE ; Beom KIM
Kidney Research and Clinical Practice 2014;33(4):199-203
BACKGROUND: The urine dipstick is widely used as an initial screening tool for the evaluation of proteinuria; however, its diagnostic accuracy has not yet been sufficiently evaluated. Therefore, we evaluated its diagnostic accuracy using spot urine albumin/creatinine ratio (ACR) and total protein/creatinine ratio (PCR) in proteinuria. METHODS: Using PCR > or = 0.2g/g or > or = 0.5g/g and ACR > or = 300mg/g or > or = 30mg/g as the reference standard, we calculated the diagnostic accuracy profile: sensitivity, specificity, positive and negative predictive value, and the area under the curve (AUC) of the receiver operating characteristic curve. RESULTS: PCR and ACR were available for 10,348 and 3,873 instances of dipstick testing. The proportions with PCR > or = 0.2g/g, > or = 0.5g/g and ACR > or = 300mg/g, > or = 30mg/g were 38.2%, 24.6% and 8.9%, 31.7%, respectively. The AUCs for PCR > or = 0.2g/g, > or = 0.5g/g, and ACR > or = 300mg/g were 0.935 (trace: closest to ideal point), 0.968 (1+), and 0.983 (1+), respectively. Both sensitivity and specificity were > 80% except for PCR > or = 0.5g/g with trace cutoff. For the reference standard of ACR > or = 30mg/g, the AUC was 0.797 (trace) and the sensitivity was 63.5%. CONCLUSION: Urine dipstick test can be used for screening in older outpatients with ACR > or = 300mg/g or PCR as the reference standard for proteinuria. However, we cannot recommend the test as a screening tool with ACR > or = 30mg/g as the reference owing to its low sensitivity.
Albuminuria
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Area Under Curve
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Humans
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Mass Screening
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Outpatients*
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Polymerase Chain Reaction
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Proteinuria*
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Reagent Strips
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ROC Curve
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Sensitivity and Specificity
3.Chemical constituents of Neoalsomitra integrifoliola.
Dongmin SU ; Wenzhao TANG ; Shishan YU ; Yunbao LIU ; Jing QU ; Dequan YU
China Journal of Chinese Materia Medica 2012;37(11):1593-1596
OBJECTIVETo study the chemical constituents of the n-BuOH fraction of 95% ethanolic extract of leaves of Neoalsomitra integrifoliola.
METHODThe compounds were isolated with kinds of column chromatography. The structures were determined by MS and NMR spectroscopic techniques.
RESULTEight compounds were isolated from the n-BuOH fraction of 95% ethanolic extract and their structures were identified as 2-phenylethyl rutinoside (1), rutin (2), kaempferol-3-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (3), isorhamnetin-3-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (4), methyl chlorogenate (5), guanosine (6), adenosine (7), myo-inositol (8), respectively.
CONCLUSIONAll compounds were isolated from this genus for the first time.
Cucurbitaceae ; chemistry ; Drugs, Chinese Herbal ; chemistry ; Organic Chemicals ; analysis ; chemistry ; isolation & purification
4.A case of pediatric tracheal inflammatory myofibroblastic tumor.
Shichao QIN ; Dongmin WEI ; Chenyang XU ; Tongdong SU ; Dapeng LEI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2023;37(10):840-842
Inflammatory myofibroblastic tumor is a rare tumor of mesenchymal origin. A case of intratracheal inflammatory myofibroblastic tumor in a male child was reported. The clinical characteristics, diagnosis, treatment and prognosis of the disease were reviewed based on the literature, and a differential diagnosis between inflammatory myofibroblastic tumor and hamartoma was performed to ultimately confirm the nature of the tumor in the child.
Humans
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Child
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Male
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Trachea/pathology*
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Granuloma, Plasma Cell/diagnosis*
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Prognosis
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Diagnosis, Differential
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Tomography, X-Ray Computed