1.Clinical controlled study of acupuncture and movement therapy for treatment of fasciitis of lumber muscles
Chinese Journal of General Practitioners 2009;8(5):344-345
One hundred and fifty-two cases of fasciitis of lumber muscles were divided into two groups.The treatment group of 75 cares war treated with acupuncture and movement therapy bared on syndrome differentiation with meridians and collaterals using points of Shuigou(DU26)or Houxi(S13),Shousanli(LI10)or Tmchong(LR3);while 77 cages in the control group were treated with simple acupuncture and Ashi points and Weizhong(BL40).The total efficacy rate Wag 86.7%in the treatment group and 64.9%in the control group(P<0.01).The effect of immediate pain relief in treatment group WaR better than that of the control group,with the VAS scores significantly decreased(P<0.01).Acupuncture and movement therapy is effective for treatment of fasciitis of lumbar muscles.
2.Effect of milrinone on refractory heart failure
Chinese Journal of Primary Medicine and Pharmacy 2014;21(12):1801-1803
Objective To investigate the effects of the milrinone in adjuvant treatment of intractable heart failure.Methods 60 cases of patients with intractable heart failure were randomly divided into observation group and control group according to hospitalization sequence,30 cases each group.The control group was given conventional therapy for heart failure,the observation group based on the use of milrinone.Changes of cardiac function index,NT-proBNP were compared between two groups before and after medication,and recorded the adverse reactions and the efficacy evaluation.Results After taking drugs,HR,LVEDD of the two groups were significantly decreased(t =5.31,5.92,4.61,4.22,all P < 0.05),SV,LVEF and 6 minutes walking distance increased significantly(t =7.22,4.78,8.78,4.56,4.11,4.05,all P < 0.05) ; group HR,LVEDD were significantly lower than those in the control group(t =4.31,4.92,all P <0.05).SV,LVEF and 6-minute walking distance was significantly higher than that in the control group(t =4.31,4.92,4.11,all P < 0.05).After taking drugs,the observation group NT-proBNP levels decreased significantly than before treatment (t =14.55,P < 0.05),and significantly lower than that in the control group (t =7.12,P < 0.05).No significant change in NT-proBNP levels before and after treatment in control group was found (t =1.03,P > 0.05).The observation group in the total effective rate was 93.33 % (28/30),the control group was 63.33% (19/30),the difference was statistically significant(x2 =5.26,P < 0.05).5 cases of adverse reactions to the observation group,4 patients in the control group,no significant difference in the adverse reactions was found between the two groups (x2 =0.67,P > 0.05).Conclusion Low dose,short-term use of milrinone can make the heart function of patients with refractory heart failure was obviously improved,significantly improve the efficacy with higher safety.
3.Expression and significance of Pokemon protein and p53 protein in ovarian carcinoma
Chinese Journal of Primary Medicine and Pharmacy 2014;21(12):1782-1784
Objective To explore the expression of Pokemon protein and p53 protein in ovarian carcinoma and assure the relationship with clinicopathologic parameters.Methods 52 cases of ovarian cancer were enrolled as the observation group,60 cases of benign ovarian tissue as the control group.Expression of Pokemon protein and p53 protein were detected by immunohistochemistry.Results The positive rate of Pokemon protein were respectively 69.2% (36/52) in the observation group and 11.7% (7/60) in the control group,a significant differences between the two groups (x2 =12.74,P <0.01).The positive rate of p53 protein were respectively 78.8% (41/52) in the observation group and 15.0% (9/60) in the control group,a significant differences between the two groups(x2 =22.71,P < 0.01).Pokemon protein expression were associated with ovarian cancer tumor invasion depth (x2 =9.16,P < 0.05),clinical stage(x2 =5.86,P < 0.05),lymph node metastasis (x2 =32.28,P < 0.01) and recurrence (x2 =27.08,P < 0.01) and no significant relationship with tumor differentiation (x2 =0.82,P > 0.05).p53 protein expression were associated with ovarian cancer tumor invasion depth (x2 =8.24,P < 0.05),clinical stage (x2 =9.24,P < 0.05),lymph node metastasis (x2 =19.62,P < 0.01) and recurrence (x2 =21.16,P < 0.01) and no significant relationship with tumor differentiation(x2 =0.77,P >0.05).By correlation analysis,Pokemon protein expression had a significant positive correlation and p53 protein(r =0.297,P < 0.05).Conclusion Pokemon protein and p53 protein had closely related with diagnosis,lesion degree and prognosis in ovarian cancer.
4.Research and analysis of college students' depression status quo and physical exercise inter-vention measures
Chinese Journal of Medical Education Research 2014;(8):833-835,836
According to the epidemic situation of depression of college students, pathogenesis and intervention measures were analyzed by literature method in this paper, focusing on exploring the principles of exercise intervention in college sports-related depression, the benefits of exercise intensity and precautions. The purpose was to provide a way for college students' reasonable intervention, as well as provide a reference for further prevention treatment of depression of college students.
5.Effect of ~(60)Co-?-Rays on the Active Component of Radix Paeoniae Rubra
China Pharmacy 2005;0(24):-
OBJECTIVE: To study the change of the active components in Radix Paeoniae Rubra before and after the radiation of 60Co-?-rays.METHODS: The content of paeoniflorin in Radix Paeoniae Rubra before and after the radiation of 60Co-?-rays was determined by HPLC on Spherigel ODS C18(150 mm?4.6 mm,5 ?m) chromatographic column.The mobile phase consisted of methanol-water(gradient elution) with the detection wavelength set at 260.5 nm.RESULTS: The content of paeoniflorin in Radix Paeoniae Rubra dropped by nearly 20% after the radiation of 60Co-?-rays.CONCLUSION: The effect of the radiation of 60Co?-rays on the active component should be taken into consideration in treating the Chinese drugs preparation of Radix Paeoniae Rubra.
6.Distribution of pathogens and research of drug resistance on 712 sputum specimens
International Journal of Laboratory Medicine 2006;0(02):-
Objective To investigate the distribution and the drug resistance of pathogens isolated from 712 sputum specimens in the hospital.Methods 712 sputum specimens collected from the hospital underwent microorganism culture and drug sensitivity test.Disc diffusion screening and the K-B disc diffusion confirmatory method were applied to detect ESBLs,K-B test was used to judge their sensitivityies to drugs.Results The positive rate of sputum culture was increasing apparently(38% in 2003,49% in 2004 respectively).Pseudomonas aeruginosa,Escherichia coli,Klebsiella pneumoniae,and Staphylococcus epidermidis,Enterobacter,and Staphylococcus aureus were six most commonly detected oxygen-dependent bacterias.The results of the drug resistance test showed that the multiple drug resistance to antibiotics was serious.More and more enterobacteriaceae producing ESBLs were found.Conclusion Gram-negative bacilli are the major pathogens in the sputum culture,multiple drug resistance is serious. Therefore monitoring drug resistance is very important for instructing clinical doctors to use antibiotics properly.
7.Significance of Detection of Serum HBV DNA in Hepatitis B Patients
Journal of Shanghai Jiaotong University(Medical Science) 2000;20(6):527-528
Objective To study the relationship between the serum HBV DNA level and theprogress of hepatitis B. MethodsHBV DNA was quantified by branch DNA signal amplification as-say(bDNA). 172 patients of different clinical types infected with HBV were investigated for HBVDNA. Results At the less than 0.7mmol/ml of HBV DNA level, 88.0% were acute patients,32.2% chronic,66.7% chronic with the fulminant hepatic failure, 19.4% cirrhotic, and 37.5% HCCpatients. The degree of fibrosis in the liver tissue is significantly higher in the group with more than 35years old. than in that with less than 35 years old ( P < 0.01 ). All chronic patients were analyzed,HBV DNA level is significantly higher in patients less than 35 years old than in patients more than 35years old ( P < 0.01 ). Conclusion This research demonstrated that existence and replication ofHBV were the main causes for the progress of hepatitis B.
8.Clinical analysis of 52 cases of acute pulmonary embolism
Clinical Medicine of China 2008;24(5):451-453
Objective To explore the early characteristics,risk factors and correct diagnosis procedure of acute pulmonary embolism.Methods The onset,axillary examination and susceptibility of 52 cases of acute pulmonary embolism between Jan 2004 and Dec 2005 were analyzed.Results The early manifestation of acute pulmonary embolism was difficulty in breathing,chest pain,hemota and fatigue.Only 11.5%patients presented all the obove symptomes at the same time.D-dimer>500μg/L was 100%.Blood gas analysis showed hypoximia in 94.2%,typical SⅠQⅢTⅢin 13.6% on electrocardiograph,pulmonary artery hypertension in 82.5%on ultrasonography,dilated right in 38.5%of all the subjects.The diagnosis rate was 82.7%at the first diagnosis.Lower limb deep vein embolism,chronic cardiac,kidney disease,malignant tumor and periooperation patients were the risk factors.Conclusion Acute pulmonary embolism is specific-free of clincial manifestation,patients with history of vertigo but excluding difficulty in breathing,chest pain,hemato should go proper examination.
9.Research into featured content P.E class to Chongqing medical colleges foreign students
Chinese Journal of Medical Education Research 2011;10(5):560-562
This article applies documentary,expert interview, questionnaire and other methods to study the physical education teaching of foreign students in Chongqing, and explores the construction of P.E features teaching content teaching to foreign students in medical colleges.
10.Progress of encephalopathy of premturity
International Journal of Pediatrics 2012;39(2):173-176
The encephalopathy of prematurity is a complex amalgam of primary destructive disease and secondary developmental disturbances.The interrelations between destructive and developmental mechanisms at cellular and molecular level in the genesis of the encephalopathy are emphasized and reviewed.We focus on its latest definition,microglia activation induced oligodendrocyte injury,neuronal/axonal impairments,and recent insights of thalamus,subplate neurons and cerebral cortex injury.