The pediatric population with the orbital and eyeball malformations has been an important part in ophthalmic plastic surgery.The pediatric is with great difference from adult in physiology and anatomy.Besides,visual function,orbit and face during childhood are still under development.The orbital deformityes during the childhood,especially for some congenital abnormalities,are always associated with or a cause of visual disfunction.And the congenital or acquired anophthalmia or microphthalm may lead to the retardation of orbital growth and overall of the face afterwards,so it is not only a simple cosmetic surgery for the oculoplastic surgery in the pediatric population,but also the reconstruction of function.Thus we should pay special attention for the oculoplastic surgery to the effect of development of visual function and orbit in the pediatric.Accordingly,it is crucial to select a proper surgical timing and method for ophthalmic plastic surgery in the pediatric.

Objective To study the relationship between the serum HBV DNA level and theprogress of hepatitis B. MethodsHBV DNA was quantified by branch DNA signal amplification as-say(bDNA). 172 patients of different clinical types infected with HBV were investigated for HBVDNA. Results At the less than 0.7mmol/ml of HBV DNA level, 88.0% were acute patients,32.2% chronic,66.7% chronic with the fulminant hepatic failure, 19.4% cirrhotic, and 37.5% HCCpatients. The degree of fibrosis in the liver tissue is significantly higher in the group with more than 35years old. than in that with less than 35 years old ( P < 0.01 ). All chronic patients were analyzed,HBV DNA level is significantly higher in patients less than 35 years old than in patients more than 35years old ( P < 0.01 ). Conclusion This research demonstrated that existence and replication ofHBV were the main causes for the progress of hepatitis B.

One hundred and fifty-two cases of fasciitis of lumber muscles were divided into two groups.The treatment group of 75 cares war treated with acupuncture and movement therapy bared on syndrome differentiation with meridians and collaterals using points of Shuigou(DU26)or Houxi(S13),Shousanli(LI10)or Tmchong(LR3);while 77 cages in the control group were treated with simple acupuncture and Ashi points and Weizhong(BL40).The total efficacy rate Wag 86.7%in the treatment group and 64.9%in the control group(P＜0.01).The effect of immediate pain relief in treatment group WaR better than that of the control group,with the VAS scores significantly decreased(P＜0.01).Acupuncture and movement therapy is effective for treatment of fasciitis of lumbar muscles.

Objective To observe the clinical effects and safety of ganciclovirum for children infectious mononucleosis.Methods 56 cases diagnosed children were divided into ganciclovirum group(n=30) and virazole group(n=26) randomly.The two groups accepted ganciclovirum and virazole treatment respectively.The clinical effects and side effects were compared.Results The fever period,the time of lymph node,liver,spleen enlargement,pharyngitis of ganciclovirum group were shorter than those of virazole group.The difference was significant.No obvious side effect was observed during ganciclovirum treatment period.Conclusion Ganciclovirum is more effective and safe for children infectious mononucleosis.

Precision medicine promotes the development of individual medicine,but also brings about problems to patients' personal privacy,especially for the protection of genetic information.The priority is to establish relative legal framework and specific regulations.America has issued Precision Medicine Initiative:Privacy and Trust Principles and Data Security Policy Principles and Framework,which have become the pioneer in the establishment of related principles and systems.In order to promote the development of Chinese laws and regulations,it is essential to use American practice as reference according to the specific national conditions,and definitely build up several principles,such as informed consent,honesty and credibility,reasonable care and benefit balance,in order to provide perfect genetic data protection system for patients.

According to the epidemic situation of depression of college students, pathogenesis and intervention measures were analyzed by literature method in this paper, focusing on exploring the principles of exercise intervention in college sports-related depression, the benefits of exercise intensity and precautions. The purpose was to provide a way for college students' reasonable intervention, as well as provide a reference for further prevention treatment of depression of college students.

Objective To analyze the effect of artery perfusion intervention combined with radiation and chemotherapy in the treatment of locally advanced cervical cancer,and to provide clinical reference.Methods One hundred and eighteen cases with locally advanced cervical cancer patients were divided into observation group and control group by random digits table method,each group 59 cases,all patients in two groups received preoperative chemoradiation,observation group based on this,and added arterial perfusion interventional chemotherapy,compared the clinical curative effect of two groups.Results The effective rate in observation group was significantly higher than that in control group[93.22％(55/59) vs.77.97％(46/59)] (x2 =5.567,P=0.018).Seventeen cases in observation group with Ⅰ and Ⅱ degree of nausea,vomiting,2 cases with Ⅲ degree of nausea,vomiting,4 cases with Ⅰ degree of bone marrow suppression,the incidence of adverse reactions were 38.98％(23/59);18 cases in control group with Ⅰ and Ⅱ degree of nausea,vomiting,3 cases with bone marrow suppression,the incidence of adverse reactions were 35.59％ (21/59),there was no statistically significant difference between two groups (x2 =0.145,P =0.703).Conclusions Preoperative arterial perfusion intervention combined with chemoradiotherapy can effectively improve the curative effect for locally advanced cervical cancer,and has no increase in adverse reactions,and has important clinical value.

Objective To investigate the effect of Calf Spleen Extractive Injection(CSEI) on immune function of immunocompromised mice. Methods BALB/C mice were divided into normal group (n=20), model group (n=20) and positive control group (n=20), CSEI high dose group (1.20 mL/kg, n=20), middle dose group (0.60 mL/kg, n=20) and low-dose group (0.30 mL/kg, n=20). Besides the normal group, mice in other groups were intraperitoneal injected cyclophosphamide at dose of 80 mg/kg for three consecutive days to induce immunocompromised model. Continuous dosing after 10 days to viscera index, index, natural killer cells (natural killer cell, NK) kill rate, the number of peripheral blood leukocytes (white blood cell, the WBC), lymphocyte count (lymphocytes, LYM) and serum against sheep red blood cells (the Sheep Red blood cell, SRBC) IgG levels as examining index, verify the CSEI effect on the regulation of immune function was low immune function in mice. Results Compared with model group, CSEI groups of high middle and low dose had improved viscera index, phagocytic coefficient, NK cell killing activity, serum specific antibody level, peripheral WBC count and lymphocyte count(P<0.05). Conclusion CSEI has possess immunomodulatory effects on the immunocompromised mice.

Objective To investigate the effect of early rehabilitation treatment on functional improvement after total knee arthroplasty. Methods 48 patients (53knees) of rehabilitation in our hospital from 2010 to 2013 were divided into 2 groups, 22 patients (25knees) in control group were given common rehabilitation training, 26 patients (28 knees) in observation group were given early rehabilitation treatment. Results All the ROM, knee score and function score of 2 groups were improved, and observation group were better than that of control group (P<0.05),at the last follow-up, the PF, BP and VT of observation group were better than control group (P<0.05) . Conclusion Early rehabilitation treatment can significantly promote the knee function recovery after surgery and improve the life quality of patients, so it deserves to be generalized.

This review will discuss aerosol device technologies available for pulmonary vaccine deliveries.The possibilities of adopting aerosol-generation for the purpose of pulmonary immunization are described.Aerosol-generation systems might offer advantages in respect to vaccine stability and antigenicity.The noninvasive,relatively safe and low-cost net of pulmonary delivery may provide great benefits to the public health vaccination campaign.