1.Survival analysis of patients with pathologic T2-3N0 squamous cell carcinoma of thoracic esophagus after esophagectomy
Dongkun ZHANG ; Xiaodong SU ; Tiehua RONG
Cancer Research and Clinic 2013;(6):375-377,381
Objective To analyze the clinicopathologic features of patients with pathologic T2-3N0 thoracic esophageal squamous cell carcinoma (ESCC) and correlation to their prognosis.Methods The clinicopathologic data of 422 patients with pathologic T2-3N0 thoracic ESCC,who were treated with surgery were analyzed.Cumulative survival rate was analyzed by the Kaplan-Meier method and compared by Log-rank test.Cox regression model was used for multivariate prognostic analysis.Results The overall 1-,3-and 5-year survival rates were 89.3 %,63.5 % and 52.5 %,respectively.Univariate analysis revealed that the factors affecting the prognosis included gender (x2 =7.45,P < 0.01),depth of invasion (x2 =7.79,P < 0.01) andtissues differentiation (x2 =15.81,P < 0.01).They were also independent prognostic factors according Cox regression multivariate survival analysis.Conclusion The gender,depth of invasion and differentiation should be independent prognostic factors of pathologic T2-3N0 ESCC.Surgery is still the standard treatment for pathologic T2-3N0 esophageal cancer.
2.Application of ultrasonically activated scalpel in open thyroid surgery
Dongkun ZHANG ; Zhuming GUO ; Quan ZHANG ; Wenkuan CHEN ; Hao LI ; Shunlan WANG
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(06):-
OBJECTIVE To investigate the use ofultrasonically activated scalpel (UAS) in open thyroid surgery. METHODS From February 2004 to March 2005, thyroidectomy were performed in 77 cases by the same operation team. Forty seven cases received UAS thyroidectomy and 30 cases underwent conventional thyroidectomy. The operation time, estimated blood loss in operation, postoperative draining volume within the 24 hours, the length of hospitalization and postoperative complications between two groups were compared. RESULTS The average operation time of lobectomy and total/subtotal thyroidectomy in the UAS group were 61?4.34 and 85?3.02 minutes, and in conventional group were 82?3.37 and 121? 2.51 minutes. There was a significant difference in average operation time (P0.05). CONCLUSION The use of UAS in thyroid surgery was safe and can reduce the operation time.
3.The Nuss procedure for complicated pectus excavatum
Liang XIE ; Gang CHEN ; Jiming TANG ; Xiaosong BEN ; Haiyu ZHOU ; Pu XIAO ; Zihao ZHOU ; Xiong YE ; Dongkun ZHANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2011;27(11):648-650
Objective To summarize the experiences of Nuss procedure for complicated pectus excavatum.Methods From August 2006 to July 2011,443 patients with pectus excavatum received Nuss operation.Among them,95 patients with complicated pectus excavatum (CT Haller index > 6) received modified technique of Nuss procedure,including multi-bar technique,oblique placed bar,double arc bar technique; fix with wire ; osteotomies ; auxiliary small incision; thoracoscopy placed by different lateral.Results All operations were successfully accomplished without severe complications.The mean operative time was (90.13 ± 39.12 ) minutes and the mean volume of blood loss was (45.41 ± 19.23 )ml.The mean hospital stay was (7.21 ± 2.87 ) days.All patients have been satisfied with their surgical correction.Therapeutic results evaluation was excellent in 75.8% of patients,good in 16.8%.Conclusion Multi modified technique of Nuss procedure can lead to a satisfactory outcome for complicated pectus excavatum patients.
4.CT morphology of mandibular bone and mandibular nerve canal in hemimandibular elongation.
Gui-mei ZHANG ; Tao WANG ; Xiaobin MAO ; Dongkun YANG
West China Journal of Stomatology 2012;30(2):152-155
OBJECTIVETo study morphology feature of mandibular anatomical characteristics and mandibular nerve canal of hemimandibular elongation (HE) using CT, and provide reference for the clinical treatment.
METHODS19 patients with HE were scanned using multidetector CT. Mimics 10.0 software was used for three-dimensional reconstruction, and CT images were reconstructed on different sections. The position of mandibular nerve canal, mandibular foramen and thickness of mandibular cortical bone were measured, and compared with control group (without mandibular lesion).
RESULTSCompared with the control group, the distance between mandibular nerve canal and mandibular surface were statistically different at the section of long axis of mandibular first molar centre (LAMFM)-lingual, long axis of mandibular second molar centre (LAMSM)-buccal, LAMSM-superior, retromolar area centre to the mandibular angle (RAC-MA)-buccal, RAC-MA-superior, RAC-MA-inferior and horizontal level of mandibular foramen under 5 mm (HLMFU5)-lingual, HLMFU5-anterior, HLMFU5-posterior (P<0.05); the thickness of mandibular cortical bone were statistically different at the LAMFM-buccal, LAMFM-inferior (P<0.05); lowest point of mandibular foramen (LPMF)-superior border of mandibular ramus (SBMR) and LPMF-inferior border of mandibular ramus (IBMR) were statistically different (P<0.05).
CONCLUSIONIn the patients with hemimandibular elongation, the thickness of mandibular cortical bone gradually decreases in all directions from the mandibular first molar to the mandibular ramus. Compared with the control group, mandibular nerve canal located buccally and superiorly at mandibular second molar and retromolar area, mandibular foramen located more anterior and lower inside mandibular ramus.
Female ; Humans ; Male ; Mandible ; Mandibular Nerve ; Molar ; Tomography, X-Ray Computed
5.Quality of life analysis of 96 patients who underwent a Nuss procedure
Xiong YE ; Gang CHEN ; Wenliang LIN ; Meixia HU ; Yanlan LI ; Yunhui LIANG ; Yanhong ZHAO ; Xiaosong BEN ; Haiyu ZHOU ; Jiming TANG ; Liang XIE ; Pu XIAO ; Dongkun ZHANG ; Zihao ZHOU
Chinese Journal of Thoracic and Cardiovascular Surgery 2012;(11):644-646
Objective The Nuss procedure is a minimally invasive pectus repair.The aim of this study was to explore the changes in quality of life in patients who underwent a Nuss procedure.Methods 96 patients,who underwent a Nuss procedure in our institution,were interviewed at preoperation,1 year after operation with the bar in place,and before the planned bar removal.The Nuss Questionnaire modified by George Krasopoulos et al,which evaluates psychosocial and physical well-being,was independently used by patients.Results Most of the scoring of the individual questions and the total score of individual patients revealed a significant improvement,both in preoperation vs.1 year after operation and 1 year after operation vs.before the planned bar removal.Conclusion The Nuss procedure has been shown to improve the quality of life in patients with pectus excavatum deformity in the short term.
6.The influence of the minimal invasive Nuss procedure on the postoperative pulmonary function of pectus excavatum patients
Guohua ZHOU ; Gang CHEN ; Liang XIE ; Jiming TANG ; Xiaosong BEN ; Haiyu ZHOU ; Dongkun ZHANG ; Xiong YE ; Zihao ZHOU ; Wenliang LIN
Chinese Journal of Thoracic and Cardiovascular Surgery 2017;33(12):733-737
Objective To study the influence of the minimal invasive Nuss procedure on the pulmonary function of post-operative pectus excavatum patients. Methods Conduct retrospective analysis on the data from 676 pectus excavatum patients who were treated by the minimal invasive Nuss procedure from August 2006 to November 2014. Wherein 182 cases have com-plete preoperative and postoperative pulmonary-function data of one year, three years. These cases were divided into 3 groups according to the age, namely, children group( from 6 to 12 years old, 34 cases) , adolescents group( from 13 to 18 years old, 80 cases) , adults group( above 18 years old, 68 cases) , among which there were 71 cases with pulmonary function data of 1 year after removal of steel plate, they were divided into 3 groups in the same way,namely, children group(20 cases), adoles-cents group(22 cases), adults group(29 cases) . To compare and analyze the pulmonary function indicatrix of patients with dif-ferent ages in preoperative stage, 1 year, 3 years postoperative stages and 1 year after dismantling the steel plate stage, and to investigate the influence of the minimal invasive Nuss procedure on the postoperative lung function. Results The pulmonary function indicatrix in preoperative stage, 1 year, 3 years postoperative stages of the children group did not have significant difference(P>0. 05); the FVC, FEV1 indicatrix of adolescents and adults groups declined after operation in 1 year and 3 years compared with the preoperative stage(P<0. 05), FEF 25% -75%, FEF 50%, FEF75% were improved after operation in 1 year and 3 years compared with the preoperative stage(P<0. 05);the pulmonary function indicatrix of three age groups in the 1 year after dismantling the steel plate stage had all improved, in which the pulmonary function indicatrix of the children group improves most significantly(P<0. 05). Conclusion After the minimal invasive Nuss procedure before the plate dis-mantling process, the pulmonary function of children patients remains to be similar. Partial ventilatory function was damaged in the adolescents and adults patients. After the plate dismantling process, the pulmonary function indicatrix of each age group hasimproved in different degrees. Improvement effect is the most significant in patients below the age of 12.