1. Comparison of the effect of percutaneous coronary intervention via radial and femoral arteries in elderly patients with coronary heart disease
Chinese Journal of Primary Medicine and Pharmacy 2019;26(16):1951-1955
Objective:
To compare the effect of percutaneous coronary intervention(PCI) via radial and femoral arteries in elderly patients with coronary heart disease(CHD).
Methods:
From March 2015 to March 2017, the clinical data of 167 elderly patients with CHD who underwent PCI in the People's Hospital of Quzhou were retrospectively analyzed.According to the different ways of artery puncture, the patients were divided into radial artery group(102 cases) and femoral artery group(65 cases). The related conditions in terms of preoperation and postoperation, changes of cardiac function before and after operation, and occurrence of complications were compared between the two groups.
Results:
The catheter insertion time and X-ray exposure time of the radial artery group were significantly longer than those of the femoral artery group[(3.47±1.04)min vs.(2.25±0.83)min, (25.17±8.49)min vs.(19.31±6.31)min,
2. Serum low-density lipoprotein receptor-related protein 6 level and its clinical significance in patients with acute myocardial infarction
Dongjian CHAI ; Jing ZHENG ; Zhenyan GAO ; Xiaoming TU ; Geyi ZHU
Chinese Journal of Postgraduates of Medicine 2020;43(2):154-157
Objective:
To investigate the clinical significance of serum low-density lipoprotein receptor-related protein 6 (LRP6) level in patients with acute myocardial infarction (AMI).
Methods:
One hundred and fifty patients with AMI were selected as the AMI group and 150 patients with suspected coronary heart disease without coronary artery stenosis were selected as control group from January 2017 to December 2018 in Quzhou People′s Hospital of Zhejiang. The serum LRP6 levels were determined by Western blot. The serum B-type brain natriuretic peptide (BNP) and cardiac troponin I (cTnI) levels were determined by enzyme-linked immunosorbent assay (ELISA).
Results:
The levels of total cholesterol (TC), triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) in AMI group were higher than those in the control group [(4.42 ± 0.79) mmol/L vs. (3.79 ± 0.82) mmol/L, (1.52 ± 0.33) mmol/L vs. (1.37 ± 0.38) mmol/L, (3.15 ± 0.34) mmol/L vs. (2.91 ± 0.28) mmol/L], and the level of high-density lipoprotein cholesterol (HDL-C) was lower than that in control group [(0.95 ± 0.26) mmol/L vs. (1.21 ± 0.33) mmol/L], and there were significant differences (