Objective:To study the environment suitability of multi-parameter patient monitor. Methods: Choosing six different types of multi-parameter patient monitor from different manufactures, we tested six main parameters of the multi-parameter patient monitor when they had gone through the environmental tests, and the test limits come from field environment. Results:Each of the samples was not up to the standards. Conclusion:At present a clear most of the multi-parameter patient monitor in the market are designed and produced for using indoors, which are not suitable for using in field environment. We need to enhance the protection of the multi-parameter patient monitor against field environment, and improve the environment suitability.

Bio-safety problem was emerging as more and more important with the development of biotechnology,and many governments concerned about it.We analyzed the different category of biotechnology related with bio-safety problem,and found out its main influencing factors and safety results.In the course of research and development of biotechnology,misuse,abuse and non-moral use are three main human factors.We concluded that the situation of bio-threat would be more diverse,and also the misuse chance would increase.It will be benefited that public health manager make regulations and legislature with full dimension of bio-safety assessment of different biotechnologies.

Objective To explore the influential factors of the healthy lifestyle of college students, so as to provide basis for drafting the health education measure appropriate for college students. Methods 5400 college students received the assessment with the healthy lifestyle scale for college students to analyze the influential factors. Results Some factors affect the healthy lifestyles of college students, such as gender, temperament, self-rated health, self-rated achievement, type of college, grade, residential peer, birth region, educational levels of parents and family' s monthly-earning, and r -square for total score and each dimension of the healthy lifestyle of college students respectively were 0. 3202,0. 4173,0. 2104,0. 2247,0. 1936,0. 0922,0. 2013,0. 2181,0. 162. Conclusion Colleges should take different measures to stimulate student interest in taking health-promoting lifestyles based on their characteristics so as to develop healthy lifestyles during their college student life.

Objective To explore the regulatory effects of IFNs on the expression of MMP - 2 andCath - D in osteosarcoma cell and provide experimental evidence for clinical treatment of osteosarcomametastasis. Methods The changes of MMP - 2 and Cath-D were half quantatively measured by Cell ELISA in a human osteosarcoma cell line OS - 732, treated with IFN - ? and IFN -?. Results The resultdemonstrated that both of IFNs were capable of significantly decreasing their expression (P

Objective: To investigate the effects of insulin on the DNA synthesis and cell cycle distribution of human periodontal ligament cells (PDLs). Methods:PDLs were treated with insulin at the doses (U/L) of 0.01～1 000 for 72 h,DNA synthesis of the cells was measured by 3H-TdR incorporation and cell cycle distribution was studied by flow cytometer. Results : Insulin at 1 U/L to 1 000 U/L showed a significant concentration dependent stimulation of 3H thymidine uptake, and the effect of insulin at 100 ～ 1 000 U/L were not statistically different from that at 10 U/L. The percentage of PDL cells in G1 phase during exponential growth was decreased by insulin, while that in S phase and (G2+M) was increased in experimental group. Conclusion: Insulin increases DNA synthesis of PDL cells ,and stimulates the transformation of cells from G1 to S phase.

Objective To investigate the correlation of platelets-to-lymphocyte ratio (PLR) with neutrophil-to-lymphocyte ratio (NLR) from pretreatment in the Xinjiang Uygur patients with nasopharyngeal carcinoma.Methods In this retrospective analysis,96 cases of nasopharyngeal carcinoma patients with pathologically diagnosis were collected.Receiver operating characteristic (ROC) curve analysis suggested that optimum PLR and NLR cut-off point for nasopharyngeal carcinoma.The patients were divided into high-PLR and low-PLR groups,high-NLR and low-NLR groups,respectively.The survival rate was calculated with Kaplan-Meier method.The Log rank statistics was used to test differences between groups.The prognostic factors that may affect patients with nasopharyngeal carcinoma in Uighur population of Xinjiang were analyzed by COX proportional hazards models.Results For high-PLR and low-PLR groups,5-year overall survival,and progression-free survival were 46.6％ and 79.3％,49.8％ and 82.7％,respectively;the difference was statistically significant (all P ＜ 0.01).For high-NLR and low-NLR groups,5-year overall survival rate,and progression-free survival rate were 41.3％ and 41.3％,50.8％ and 82.5％,respectively;the difference was statistically significant (all P ＜ 0.01).Univariate analysis showed that N stage,clinical stage,NLR,and PLR had significantly impact on overall survival and progression-free survival (all P ＜ 0.05);multivariate analysis showed that PLR and clinical stage had statistical significance in Uighur patients with nasopharyngeal carcinoma for progression-free survival and overall survival (all P ＜ 0.05).Conclusions PLR may be independent factor that influences the prognosis of patients with nasopharyngeal carcinoma in Uighur population of Xinjiang.

Objective To observe the protective effect of dexamethasone, the inhibitor of nuclear factor-Kappa B, on the ischemia-perfusion injury of rat lung during the period of lung preservation. Methods Twenty-four rats were randomly divided into two groups: the control group and the trial group. The harvested lung blocks were flushed with and stored in the low-potassium-dextran (LPD) solution in control group, but in the trail group LPD containing dexamethasone solution was used. The lungs were stored at 4 ℃ for 16 h in both groups. The isolated rat lung reperfusion models were established and the donor lungs were perfused for 1 h. PaO_2 and PawP were measured at every 15 min intervals during reperfusion. After reperfusion, the lung tissue wet-to-dry (W/D) ratio and myeloperoxidase (MPO) activity were obtained. The protein and mRNA expression of intercellular adhesion molecule-1 (ICAM-1), nuclear factor-Kappa B (NF-?B) was also detected by using immunohistochemistry and semi-quantitative RT-PCR at the end of reperfusion. Results The levels of decreased PaO_2 and increased PawP in trail group were lower than in control group at the every interval time in the samples obtained 15 min after reperfusion (P

Objective To evaluate the protective effect by inhibiting nuclear factor-kappa B (NF-?B) by N-acetyl-L-cysteine(NAC) on donor rat lung. Methods 24 SD rats were randomly divided into two groups, the control group and the experiment group. The harvested lung blocks were flushed with and stored in the low-potassium-dextran (LPD) solution in control group, but in the experiment group, LPD solution containing NAC was used. The lungs were preserved at 4℃ for 16 hours in both groups. Isolated rat lung reperfusion models were established and the donor lungs were perfused for 1 hour. PaO_2 and PAwP were measured at every 15 min intervals during reperfusion. After reperfusion, the lung tissue wet-to-dry (W/D) ratio and myeloperoxidase(MPO) activity were obtained. The protein and mRNA expressions of intercellular adhesion molecule-1(ICAM-1) and nuclear factor-kappa B(NF-?B) were also observed by using immunohistochemistry and semi-quantitative RT-PCR at the end of reperfusion. Results After reperfusion for 60 minutes, in experiment group, PaO_2 drop in and increase PAwP lower than in control group (P

Objective To investigate expression of elderly patients with endometrial cancer of estrogen receptor and progesterone receptor and its clinical significance.Methods 45 elderly patients with endometrial carcinoma from March 2012 to June 2014 were selected as the observation group, over the same period healthy women with normal endometrium as control group, using S-P immunohistochemical method, to detect the expression of receptor and progesterone receptor in two groups.Results In observation group, estrogen and progesterone receptor positive expression rates were 60.00%, 46.67%, compared with control group(93.33%, 86.67%), was significantly lower (P<0.05).Patients with low differentiation of estrogen and progesterone receptor, positive expression rate was 37.50%, 25.00%, was lower than other two groups, but which had no difference.Estrogen, progesterone receptor positive expression rates in progress stage were 35.71%, compared with patients ( 80.65%, 74.19%) in early stage, was significantly lower (P<0.05).The positive expression rate of estrogen receptor in patients with lymph node metastasis was 66.67%, compared with the patients with no metastasis, the difference was not statistically significant.The positive expression rate of progesterone receptor was 76.67%, compared with the non metastasis group (46.67%), and was significantly lower (P<0.05).Conclusion The expression of estrogen and progesterone can reflect the biological behavior and prognosis of endometrial carcinoma in aged patients, and have important significance for clinical diagnosis and treatment.