4.Hypertrophic cardiomyophthy: a family report.
Hai-Yun DONG ; Xiu-Ying WANG ; Yi XU
Chinese Journal of Contemporary Pediatrics 2010;12(6):1 p folowing 512-1 p folowing 512
Adolescent
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Adult
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Cardiomyopathy, Hypertrophic
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genetics
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Child
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Humans
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Male
5.Correlation between Angiotensin Converting Enzyme Gene Polymorphism and Kawasaki Disease
dong-hai, LIU ; xiu-ying, WANG ; yi, XU
Journal of Applied Clinical Pediatrics 1986;0(01):-
Objective To investigate the correlation between angiotensin converting enzyme(ACE) gene polymorphism and kawasaki disease(KD).Methods A 287 bp Alu fragment in intron 16 of the ACE gene was used as insertion(I)/deletion(D) polymorphism marker. The ACE genotype of 28 children (10 children complicated coronary dilataltion) with KD and 35 healthy controls were detected by polymerase chain reaction (PCR), and ACE concentration in blood serum was measured by ultraviolet-spectrophotometer assay.Results 1.The ACE concentration was significantly higher in KD group than that in healthy control group(P
6. Bisphosphonates promoting repair of injured vertebrae after thoracolumbar fracture internal fixation: A randomized controlled study
Academic Journal of Second Military Medical University 2017;38(4):443-446
Objective To explore the anti-osteoporosis effect of bisphosphonates on repairing injured vertebrae after thoracolumbar fracture internal fixation through a randomized controlled study. Methods Eighty-four patients with thoracolumbar fracture treated by orthopaedic internal fixation in Department of Orthopaedics, Nanjing General Hospital from Jun. 2014 to Jun. 2015 were included, and the patients were divided into the bisphosphonate treatment group (n=42) and control group (n=42) by random number method. The patients in both groups were given the routine anti-osteoporosis drugs such as calcitriol and calcium carbonate D3 after surgery; in addition, the patients in the bisphosphonate treatment group were also given alendronate sodium D3 tablets (each containing alendronate sodium 70 mg, 1 tablet per week), while the control group received a placebo. The bone mineral density (BMD) in thoracolumbar vertebral injury area of patients in the two groups was measured and compared at 1 month, 3 months, 6 months and 1 year after surgery. Results The BMD values of patients in two groups were significantly decreased immediately after reset compared with preoperation, and then they were increased continuously in follow-up. There was no significant difference in BMD between the two groups at 1 month or 3 months after sursery (P>0.05), while the BMD in the bisphosphonate treatment group was significantly higher than that in the control group at 6 months and 1 year after surgery (P<0.05). Conclusion Bisphosphaonate drugs can accelerate the repair of vertebral osteoporosis after thoracolumbar fracture internal fixation, showing a good clinical application value.
7.Non-invasive temperature estimation using backscattered ultrasound.
Hai-dong XU ; Zhao-ying ZHOU ; Ran LIU
Chinese Journal of Medical Instrumentation 2002;26(6):434-452
This article describes non-invasive temperature estimation using backscattered ultrasound based on the random medium model of biotissue. Its model, algorithm and key technology are introduced here and its development trend is discussed too.
Algorithms
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Computer Simulation
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Equipment Design
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Hyperthermia, Induced
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instrumentation
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Models, Biological
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Thermometers
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Ultrasonics
8.Premature ovarian failure treated with acupoint catgut implantation and artificial periodic therapy: a randomized controlled trial.
Wei-Dong LI ; Hua-Qun XU ; Jing-Qiang TANG ; Hai-Song QIU
Chinese Acupuncture & Moxibustion 2014;34(1):29-33
OBJECTIVETo compare the difference in the clinical efficacy on premature ovarian failure (POF) between the acupoint catgut implantation combined with artifical periodic therapy and the simple artificial periodic therapy and explore its effect mechanism.
METHODSSixty-five patients of POF were randomized into the two groups. In a western medication group, 32 cases were treated with the artificial periodic therapy with the oral administration of medroxyprogesterone acetate tablets. In a catgut implantation + western medication group, 33 cases were treated with the acupoint catgut implantation combined with artificial periodic therapy. The acupoints of Neiguan (PC 6), Zusanli (ST 36), Guanyuan (CV 4) and Sanyinjiao (SP 6) were selected. The treatment was lasted for half a year and the follow-up visit was for another half a year in the two groups. Kupperman index was used to assess the improvements in the clinical symptoms. The levels of serum sexual hormones such as follicle stimulating hormone (FSH) and estradiol (E2) were evaluated of the patients in the two groups before and after treatment. The efficacy was compared between the two groups.
RESULTSThe scores of the clinical symptoms were all significantly improved after treatment and in the follow-up in the two groups (P < 0.01, P < 0.05). In the 6-month follow-up visit after treatment, the result in the catgut implantation + western medication group was better than that in the western medication group (8.17 +/- 1.19 vs 13.68 +/- 1.08, P < 0.01). FSH was reduced after treatment in the two groups (all P < 0.01) and E2 was increased (all P < 0.05). The curative and remarkably effective rates were 75.8% (25/33) and 81.8% (27/22) after treatment and in the follow-up visit in the catgut implantation + western medication group, which were better than 67.9% (19/28) and 53.6% (15/28) in the western medication group separately (P < 0.05, P < 0.01).
CONCLUSIONThe acupoint catgut implantation combined with artificial periodic therapy achieve the remarkable improvements in the clinical symptoms of POF in the patients and the better results as compared with the simple western medication therapy. The combined therapys efficacy is stable and the long-term efficacy is apparently superior. The effect mechanism is related to the improvements in the serum sexual hormone levels.
Acupuncture Points ; Acupuncture Therapy ; Adolescent ; Adult ; Catgut ; utilization ; Female ; Follicle Stimulating Hormone ; metabolism ; Humans ; Primary Ovarian Insufficiency ; metabolism ; therapy ; Prostheses and Implants ; Treatment Outcome ; Young Adult
9.L1-L2 complete traumatic fracture-dislocation of the lumbar spine: a case report.
Gang-xiang WANG ; Zhi-gang WANG ; Hai-dong ZHOU ; Hong-yu XU
China Journal of Orthopaedics and Traumatology 2015;28(9):868-869
Adult
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Humans
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Joint Dislocations
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surgery
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Lumbar Vertebrae
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injuries
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surgery
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Male
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Spinal Fractures
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surgery
10.The effects of mild stress to gastrointestinal motility and oxytocin in hypothalamic paraventricular nucleus of rats
Hengcai ZHOU ; Zhaoming ZHOU ; Xi HAI ; Meng XU ; Zhe CHEN ; Rong DONG
Chinese Journal of Behavioral Medicine and Brain Science 2013;22(9):788-790
Objective To study the changes of gastrointestinal movement function in rats with chronic unpredictable mild stress(CUMS) and explore the mechanisms underlying it.Methods The rats were divided into stress model group and control group.The stress model rats were induced by 21-day chronic unpredictable mild stress as well as social-isolated fed.The rate of ink propulsion of gastrointestinal tract and the contraction of intestinal canal in rats were observed.Immunohistochemistry was adopted to detect the expression of OT in rats.Results (1) After the models were induced,weight-gain and sucrose preference of model group ((69.97 ± 9.81) g,(49.05± 5.98) g) were lower than those in control group ((116.27 ± 13.60) g,(83.51 ± 3.08) g) (P < 0.001),and both the crossing-score and rearing-score ((24.00 ± 13.52),(3.90 ± 2.51)) were lower than those in control group ((53.60 ± 27.98),(11.50 ± 8.85)) in the open-field test.(2) The rate of ink propulsion of model group ((67.33 ± 6.24) %) was decreased when compared to the control group ((76.83 ± 10.00) %) (P < 0.05),and the intestinal canal contraction amplitude and contraction frequency ((1.37 ± 0.18) g,(0.58 ± 0.02) S-1) were lower than those in control group ((1.88 ± 0.13) g),(0.62 ± 0.04) S-1) (P < 0.05).(3) Compared with the control group (6.07 ± 3.71),OT immunoreactive substance was increased in model group (59.17 ± 16.08) of rats (P<0.001).Conclusion Chronic stress can cause the decrease in gastrointestinal movement function of rats.These changes may be related to the increased expression of OT in paraventricular nucleus.