1.3D Reconstruction for Medical Image Based on ITK and OpenGL
Baoping HU ; Xiuzhen DONG ; Feng FU
Chinese Medical Equipment Journal 2009;30(7):14-16
Obiective To develop a new medical image processing platform based on ITK and OpenGL. Methods This platform was designed by VC ++ 6.0 and MFC class library. ITK class library was wsed to fulfill reading, writing,segmentation of images and iso-surface extraction. OpenGL was wsed to realize 3D surface rendering. Results The new 3D-medical imaging reconstruction system was designed. Conclusion This system not only can provide graphic interface which can not be realized by using ITK class library, but also enhance the ability of three-dimension visualization by using OpenGL.
2.Study on dielectric properties of human breast tissues
Qimei LIAO ; Xiuzhen DONG ; Feng FU
International Journal of Biomedical Engineering 2006;0(04):-
Breast cancer is one of the most common malignant tumours in women. It threatens the health and life of women. The imaging technology of breast electrical impedance scanning based on the dielectric properties of breast tissues develops a new aspect of early detection and auxiliary diagnosis of the breast cancer. The dielectric properties of human breast tissues reflect the pathological and physiological state of breast tissues and the measurement of these properties serves as the basis for electrical impedance scanning(EIS) technology. In this paper, the measurements and results of dielectric properties of human breast tissues are discussed, and the problems of measurement and the application perspective of the EIS are also explored.
3.Stem cells and repair of injured retina
yong, LIU ; dong-fu, FENG ; zhi-an, ZHU
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(02):-
Recently,the progress in employing transplanting stem cells to cure injured retina is very fast and has been continuously yielding exciting results.Various sources are used in the studies,including retina-derived cells such as M?ller cells and ciliary body cells,and non-retina-derived cells such as embryonic stem cells and brain-derived stem cells.This review briefly discusses the recent progress of these studies.
4.Role of mitochondrial ATP-sensitive potassium channels in attenuation of cerebral ischemia-reperfusion injury by dexmedetomidine in rats
Feng YUAN ; Hongguang FU ; Kai SUN ; Tieli DONG
Chinese Journal of Anesthesiology 2014;34(4):500-502
Objective To evaluate the role of mitochondrial ATP-sensitive potassium (mito-KATe) channels in attenuation of cerebral ischemia-reperfusion (I/R) injury by dexmedetomidine in rats.Methods One hundred and twenty healthy male Wistar rats,weighing 290-340 g,were randomly assigned into 5 groups (n =24 each) using a random number table:sham operation group (group S) ; group I/R; dexmedetomidine group (group D) ; 5-HD (a specific blocker of mito-KATPchannel) group and 5-HD + dexmedetomidine group (group 5-HD + D).The rats were anesthetized with intraperitoneal chloral hydrate.Focal cerebral I/R was produced by 2 h middle cerebral artery occlusion followed by reperfusion.In group D,dexmedetomidine 50 μg/kg was injected intraperitoneally before ischemia and after onset of reperfusion.In group 5-HD,5-HD 30 mg/kg was injected intraperitoneally at 1 h before ischemia.In 5-HD + D group,5-HD 30 mg/kg was injected intraperitoneally at 1 h before ischemia and the other procedures were similar to those previously described in group D.Twelve rats were chosen at 24 and 48 h of reperfusion to assess the neurological deficit score (NDS).The animals were then sacrificed and brains were removed for determination of cerebral infarct size by TTC staining.Results Compared with S group,NDS and cerebral infarct size were significantly increased at each time point in the other four groups (P < 0.05).Compared with group I/R,NDS and cerebral infarct size were significantly decreased in D and 5-HD + D groups (P < 0.05),and no significant change was found in the parameters mentioned above in 5-HD group (P > 0.05).Compared with group D,NDS and infarct size were significantly increased in group 5-HD + D (P < 0.05).Conclusion Mito-KATP channels are involved in reduction of I/R-induced cerebral injury by dexmedetomidine in rats.
5.Comparison of curative effect and thrombolysis time between r-tPA application and urokinase in the interventional thrombectomy and thrombolysis for acute and severe pulmonary embolism
Qichen FENG ; Xuan LI ; Guoxiang DONG ; Jun FU ; Changming WANG
Journal of Peking University(Health Sciences) 2014;(3):460-463
Objective:To study the influence of r-tPA and urokinase in curative effect and thrombolysis time on patients with acute and severe pulmonary embolism after interventional thrombectomy .Methods:After reviewing and analyzing the clinical data of 19 acute and severe pulmonary embolism patients , we classified them into two groups in accordance with the application of r-tPA and urokinase to compare the changes of their heart rate , blood pressure , pulmonary arterial pressure , arterial partial pressure of oxygen and hemachrome before and after thrombolysis , as well as the thrombolysis effect time the two groups took.Results: The heart rate, blood pressure, pulmonary arterial pressure , arterial partial pressure of oxygen of the patients in both groups gained remarkable improvement after operation ( P<0 .05 );the pulmonary arterial pressure of the r-tPA patient group dropped but not significantly compared with that before operation ( P>0.05); the pulmonary arterial pressure of the urokinase patient group dropped significantly compared with that study before operation ( P<0.05 ); the hemachrome of both patient groups did not significantly drop after operation ( P>0 .05 );the thrombolysis effect time by adop-ting r-tPA was remarkably shorter than that caused in thrombolysis by adopting urokinase ( P<0 .05 ) . Conclusion: Both r-tPA and urokinase are effective in interventional thrombolysis for acute and severe pulmonary embolism .However , r-tPA could significantly shorten the time caused in thrombolysis without increasing any bleeding risk.
6.Individualized teaching mode in course of Digital Signal Processing
Ruigang LIU ; Feng FU ; Meng DAI ; Xiuzhen DONG
Chinese Medical Equipment Journal 2015;36(5):143-145
The communication between the students and the teacher was introduced from three aspects of foregone course, communication channel as well as homework and experiment. The individualized teaching mode was described involving expounding common difficulty, assigning and reading over the homework, individualized tutoring after school, on-line responding to the student's question, prompting the student to complete programming and answering questions in evening classes. It's pointed out that the individualized teaching has to take both common knowledge and student difference into considerations. Individulized mode enhances the teaching efficacy greatly.
7.Develepment and application of the inserted mouth gag
Dongmei WANG ; Yuxi FENG ; Wei FU ; Hui DONG ; Li TIAN
Chinese Journal of Practical Nursing 2015;(29):2242-2244
Objective To evaluate the effectiveness of mouth gag which can inserted into lavage tube during gastric lavage. Methods The Sixty- six cases of acute poisoning patients with gastric lavage according to random number table method were randomly divided into two groups, 33 cases in each group. Observation group used the inserted mouth gag, and the control group used the metal ones. Results The observation group were lower than the control group at the time required to insert the lavage tube [(2.23±0.19)s to (3.26±0.30)s] and the incidence of complication rate [18.2%(6/33) to 45.5%(15/33)], the oral cavity bleeding [6.0%(2/33) to 30.3%(10/33)], lavage tube displacement [0(0/33)to 24.2%(8/33)], lavage tube twisting[0(0/33) to 24.2%(8/33)], the difference was statistically significant (P<0.01), while higher in the rate of successful intubation[100.0%(33/33)] to [54.5%(18/33)], the difference was statistically significant, χ2=19.4,P<0.01. Conclusions The application of the mouth gag which can insert into gastric lavage improved the successful intubation rate, saved the rescue time, reduced the complication and improved the nursing quality.
8.Post-processing algorithm on images of electrical impedance tomography
Ruigang LIU ; Xiuzhen DONG ; Feng FU ; Fusheng YOU ; Xuetao SHI
Chinese Medical Equipment Journal 2004;0(08):-
Objective To study the image processing methods of electrical impedance tomography(EIT) in order to improve the display quality.Methods Evaluate the conductivity of the nodes using the conductivity of the adjacent triangle elements.The conductivity of any point in one triangle element was calculated according to the conductivity of 3 vertexes of the element by 2D linear interpolation method.Results The original blocky images of electrical impedance tomography by the triangle elements can be transformed into smoothing images.Conclusion The visual quality of the images is improved greatly.The image processing method is adaptive to all kinds of images of electrical impedance tomography based on triangle element.
9.Simulation study based on models of cerebral hemorrhage in electrical impedance tomography
Ansheng NI ; Guosheng YANG ; Xiuzhen DONG ; Feng FU ; Xinya ZHU
Chinese Medical Equipment Journal 2004;0(08):-
Objective To build finite-element models of cerebral hemorrhage on which a simulation study of electrical impedance tomography(EIT) is based.Method With a kind of four-layer concentric circle model of head,finite-element method and dynamic NOSER algorithm are performed to reconstruct the images.Result As to the single-focus model of the cerebral hemorrhage,the focus can be clearly imaged,while to the several-focus model,the focuses can be imaged with vaguely adjacent boundaries.Conclusion The dynamic NOSER algorithm is an effective method to image cerebral hemorrhage in EIT.
10.Effect and influencing factors on 131I treatment for cervical lymph node metastasis from papillary thyroid cancer
Yun DONG ; Fang FENG ; Chao MA ; Hongliang FU ; Hui WANG
Chinese Journal of Nuclear Medicine and Molecular Imaging 2016;36(4):330-333
Objective To assess the effect and influencing factors on 131I treatment for cervical lymph node metastasis (LNM) after operation in patients with PTC.Methods PTC patients (n =117;45 males,72 females;average age (45.17± 15.50) years) with postoperative cervical LNM from January 2010 to December 2014 were analyzed retrospectively.LNM was diagnosed by surgical pathology,imaging results and clinical follow-up.Single factor analysis was performed in age,gender,operation mode,TNM stage,131I treatment time and other factors.The results for 131I treatment effect included CR,PR,NC.Two-sample t test and x2 test were used.Results Among the 117 PTC patients with postoperative LNM,53 (45.3%) cases had non-131 I-avid metastasis.Fifty of the 64 (54.7%) patients with 131I-avid metastasis were treated with 131I.Nineteen patients (38.0%) achieved CR,22 (44.0%) achieved PR,and 9 (18.0%) showed invalid results.Fourteen of the 64 patients underwent another cervical lymph node dissection.Nine patients achieved CR,5 patients achieved PR,and 4 PR patients were then treated with 131I and finally achieved CR.Single factor analysis showed that the influencing factors of non-131I-avid lymph node included patients' age (t =3.459),serum Tg level (x2 =6.698) and metastasis with 1s F-FDG uptake (x2 =26.928;all P<0.05).The influencing factors of 131I treatment effect included lymph node dissection procedure (x2 =6.487),unilateral or bilateral lesion (x2=5.187) and LNM size (x2=8.099;all P<0.05).Conclusions 131I treatment is ineffective for nearly 50% of patients with non-131I-avid LNM.The influencing factors of 131I treatment effect include the lymph node dissection procedure,unilateral or bilateral lesions and LNM size.