Cardiovascular Diseases ; psychology ; Humans ; Life Style

Cerebral ischemic postconditioning refers to conduct a series of intermittent occlusion in order to reduce ischemia-reperfusion injury during the early reperfusion after cerebral ischemia.Because of its good prospects for clinical application,it has attracted widespread attention in recent years.This article reviews the neuroprotective mechanisms of ischemic postconditioning.

Objective: This work studied platelet-neutrophil aggregates (PNA) expression in patients with acute ST-segment elevation myocardial infarction (STEMI). Methods: Our research included in 2 groups: STEMI group, n=40 patients admitted in our hospital and Control group, n=30 normal subjects. Blood levels of PNA, platelet-monocyte aggregates (PMA) and platelet-lymphocyte aggregates (PlyA) were measured by lfow cytometry at admission and the results were compared between 2 groups. Results: Compared with Control group, STEMI group had similar blood levels of PlyA and PMA,P=0.245 andP=0.312; while increased blood level of PNA,P<0.05. Correlation analysis showed that platelet-leukocyte aggregates (PLA) level was positively related to CK-MB (r=0.4992,P<0.01) and cTnI (r=0.4365,P<0.01). Conclusion: Blood level of PLA, especially PNA was significantly higher in STEMI patients which suggested that increased PNA might be sued as a new index for AMI diagnosis in clinical practice.

Objective: To explore the relationship between endogenous estrogen level and myocardial no-reflow after reperfusion in postmenopausal acute ST-elevation myocardial infarction (STEMI) patients. Methods: A total of 100 postmenopausal STEMI patients with percutaneous coronary intervention (PCI) were enrolled and divided into 2 groups: Reflow group,n=77 and No-reflow group,n=23. Myocardial no-reflow was defined by TIMI≤2 grade or TIMI 3 grade and MBG≤2 grade after PCI. Blood levels of endogenous estrogen were examined before PCI; the relationship between endogenous estrogen level and myocardial no-reflow was assessed by Logistic regression analysis. Results: Compared with Reflow group, No-reflow group showed increased blood levels of estrone, estradiol, high sensitivity C-reaction protein (hs-CRP),P<0.05 and decreased sex hormone binding globulin (SHBG),P<0.05. Univariate analysis indicated that the length of lesion, thrombus score≥4, blood levels of estrone, estradiol and hs-CRP were positively related to no-reflow occurrence,P<0.05. Multi Logistic regression analysis presented that thrombus score≥4 (OR=4.994, 95%CI 1.987-10.518,P=0.035) and estradiol level (OR=4.091, 95% CI 1.105-8.582;P=0.046) were the independent risk factors for no-reflow occurrence. Conclusion: High blood level of endogenous estrogen was positively related to myocardial no-reflow after PCI in postmenopausal STEMI patients, which implied that endogenous estrogen might be the independent risk factor for no-reflow occurrence.

Objective To investigate the mental health status of patients with coronary artery stent implantation. Methods Symptom Checklist (SCL-90) was used to evaluate the mental health conditions of 218 patients after coronary artery stent implantation with man-machine conversation and computer evaluation. Results It was found that 48 cases in excellent mental health, accounting for 22.02%; 56 cases in good mental health condition, accounting for 25.69%; 82 cases in normal mental health condition, accounting for 37.61%; and 32 cases in poor mental health, accounting for 14.68%. In addition to the interpersonal factor, hostility and psychosis factors, the other six factors’overall average score was more than 2. More than 50% of the staff scored greater than 3, and their average positive factors were greater than 43 items in somatization, depression, anxiety and fear. Conclusion The patients after coronary artery stent implantation suffered from many psychological problems.

0.05). Conclusion The rapid paper strip method could be applied as the rapid method for monitoring the fecal colifom group in surface water.

Objective To detect the effect of the antiphospholipid antibodies on the Schwann cells in vitro and to find if the Extract of Ginkgo biloba 761(EGb761)has any protective effects.Methods The immunoglobulins(Ig)were extracted from the serum of the patient with autoimmune polyneuropathies and those with controls.Ig only or Ig plus calf serum(served as complement)were added into the culture solutions of the Schwann cells.The density of the cell in one high power field,the cell perimeter and area were detected and compared to those blank and those controls.Results The shape of the Schwann cells in both the Ig and Ig plus calf serum solution were greatly changed.The densities of the cells in them were both lower than the blank ones,with more severe in the cells with calf serum.There was no significant different between the solutions with or without EGb761.Conclusion Ig from the patients with autoimmune polyneuropathies could attack the Schwann cells in vitro,with the existence of complements,the destruction was even more severe.No protection of EGb761 could be found in these situations.

Objective To introduce the clinical significance and pathophysiologic aspects of the circulatory and cardiac complications in terminal stage cirrhosis.Methods Recently relevant literatures were reviewed and summarized.Results Haemodynamic changes in cirrhosis arose on the basis of combined humoral and nervous dysregulation,with abnormalities in cardiovascular regulation,volume distribution and cardiac performance.Conclusion Comprehending the mechanisms of cardiovascular complications will contribute a lot for the treatment of terminal stage cirrhosis.

OBJECTIVE To evaluate the effectiveness of applying neuronal stem cells to bridging a 10mm long facial nerve defect in rabbits using a tissue engineered artificial nerve. METHODS Thirty-six Japanese white rabbits were randomly divided into three groups of 12. Group A: chitosan guidance channels with collagen protein sponge were filled with neuronal stem cells and NGF; Group B: chitosan guidance channels with collagen protein sponge were filled with NGF; Group C: autograft nerve. A series of examinations were performed, including electrophsiological methods, histological staining of nerve, Brdu and S100 immunohistochemical staining, at 12 weeks after operation. RESULTS At 12 weeks after operation, all examination results from Group A were better than from Group B(P0.05). CONCLUSION Neuronal stem cells can be used as seeding cells in peripheral nerve tissue engineering for repairing 10mm facial nerve defects.

Objective:To investigate the mechanism of the effect of tonifying kidney recipes(TKR) on osseointegration of the Titanium Implants by established animal model of osteoporosis rats.Methods:Fifty-four female SD rats were randomly divided into three groups:A:Sham group, B:ovariectomy(OVX) group C:OVX+TKR group. After operation, tonifying kidney recipes was given orally in C group. The results were observed by bone histomorphometry. Results:Trabeculae area (Tb?Ar,%), trabeculae width (Tb?Wi), combined bone lamella width (CBLW), osteoblast number (OB?N) in C group were significantly increased compared with B group (P