1.The Relationship of Ki-67, Proliferating Cell Nuclear Antigen, AgNORs and p53 Protein Expression in Astrocytoma.
Dong Ja KIM ; Jae Weon LIM ; Yoon Kyung SOHN
Korean Journal of Pathology 1999;33(1):25-31
The grading of astrocytoma has traditionally relied on histological assessment, but there are some differences in their parameters, application, and reproducibility. Recently, numerous studies have attempted to correlate biological aggresiveness with tumor proliferation index using new immunohistochemical methods. The purpose of this study is to correlate the histopathological grades of astrocytoma with the expression of Ki-67, PCNA, p53 protein and AgNORs. The paraffin sections of 41 consecutive cases of astrocytomas were examined. Histologically the tumors were graded as three groups under the St. Anne-Mayo system and showed 14 cases in grade II, 15 cases in grade III and 12 cases in grade IV (glioblastoma multiforme). As a result, the Ki-67 labelling index and p53 protein expression tended to increase with increasing grade of malignancy. But the univariate analysis showed that there was no significant difference between the tumor grades (p>0.05). The PCNA labelling index and number of AgNORs revealed striking differences between the grade II and grade III astrocytomas (p<0.05). We concluded that the PCNA labelling index and AgNORs counting are useful markers for differentiation between grade II and III astrocytomas.
Astrocytoma*
;
Paraffin
;
Proliferating Cell Nuclear Antigen*
;
Strikes, Employee
2.Budd-Chiari syndrome by membranous obstruction of inferior vena cava: comparison of sonography and computed tomography.
Dong Ho LEE ; Jae Hoon LIM ; Young Tae KO ; Yup YOON ; Joo Won LIM
Journal of the Korean Radiological Society 1992;28(3):387-392
Membranous obstruction of the hepatic inferior vena cava(MOVC)is one of the common causes of Budd-Chiari syndrome. The aim of this study is to ascertain and compare the characteristic sonographic and CT findings of Budd-Chiari syndrome caused by MOVC. We studied 10 patients of Budd-Chiari syndrome caused by MOVC through sonography and CT. MOVC was confirmed by operation and/or inferior vena cavography. The cases included 9 men and one woman. With sonography. IVC obstruction was diagnosed in 9 cases. The cause of IVC obstruction was web in 5 cases and fibrous cord in 3 cases. The cause was unspecified in on case. Obliteration of the hepatic veins and intrahepatic collateral vessels were delineated in 9 cases. With color doppler sonography, the directions of blood flow of the hepatic veins through the intervenous communication were fairly well demonstrated in all 5 cases. With CT, IVC obstruction was diagnosed in 7 cases. The obliteration of the hepatic segment of the IVC were segmental in 6 cases and diffuse in one case. Ct demonstrated communicating vessels between the hepatic veins in 3 cases. Furthermore. Systemic collateral vessls(azygos and hemiazygos veins. Veins along the abdominal wall, and internal mammary veins)were demonstrated in all cases. Liver cirrhosis was combined in all cases and hepatoma developed in 4 cases. Sonography is useful to detect the MOVC and to demonstrate hepatic venous obstruction and intrahepatic collateral vessels. Color doppler sonography is easily performed to show the direction of the blood flow through interconnecting vessels. CT shows the obliterated segment of the IVC clearly and multiple prominent systemic coliaterals. In conclusion, and Budd-Chiai syndrome caused by MOVC is accurately diagnosed by combined color doppler sonography and CT.
Abdominal Wall
;
Budd-Chiari Syndrome*
;
Carcinoma, Hepatocellular
;
Female
;
Hepatic Veins
;
Humans
;
Liver Cirrhosis
;
Male
;
Ultrasonography
;
Veins
;
Vena Cava, Inferior*
3.Frontalis muscle transfer technique through single inscision in blepharoptosis.
Dong Hoon WOO ; Dong Hun LIM ; Chin Ho YOON ; Han Joong KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1991;18(4):708-715
No abstract available.
Blepharoptosis*
4.Superselective Embolization of Renal Angiomyolipoma.
Jae Hoon LIM ; Young Tae KO ; Dong Ho LEE ; Joo Won LIM ; Yup YOON ; Tae Hoon KIM
Journal of the Korean Radiological Society 1994;30(3):549-554
PURPOSE: Authors retrospectively evaluated the efficacy of superselective renal arterial emboliation in 5 patients with symptomatic renal angiomyolipoma. MATERIALS AND METHODS: Five Patients with renal angiomyolipoma who had been treated with superselective renal arterial embolization were analysed retrospectively. Two patients who had multiple bilateral lesions were associated with tuberous sclerosis. The mbolic materials used were absolute alcohol in 6 sessions, absolute alcohol mixed with lipiodol in one session, and polyvinyl alcohol in one session. RESULTS: We could observe devascularization of the tumor on the post-embolization arteriograms. The symptoms such as flank pain were improved in all patients during the follow-up period of 3 months to 3years. CONCLUSION: Superselective renal arterial embolization is an effective and safe procedure in the management of renal angiomyolipomas.
Angiomyolipoma*
;
Ethanol
;
Ethiodized Oil
;
Flank Pain
;
Follow-Up Studies
;
Humans
;
Polyvinyl Alcohol
;
Retrospective Studies
;
Tuberous Sclerosis
5.Adenocarcinoma in the duodenal bulb and proximal descending duodenum: UGI, US and CT findings.
Tae Hoon KIM ; Young Tae KO ; Dong Ho LEE ; Jae Hoon LIM ; Yup YOON ; Joo Won LIM
Journal of the Korean Radiological Society 1993;29(5):1007-1014
The findings of upper gastrointestinal series(UGI), computed tomography (CT), and sonography(US) of ten duodenal adenocarcinoma confirmed by surgery (n=7) and endoscopic biopsy (n=3) were retrospectively analyzed. We performed US in all cases, CT and UGI in 8 out of 10 cases. UGI showed 4 cases of ulcerating type, 3 of stenotic type, and one failed to visualize duodenum due to previous gastrojejunostomy. UGI was more accurate in depicting the mucosal changes such as ulcer, however, it played a limited role in the evaluation of extraluminal extension. US showed 4 cases of hypocchoic wall thickening, 3 of hypoechoic extraluminal mass, and one of polypoid intraluminal mass but 2 were not detected on US. US accurately detected hepatic and pancreatic metastasis, however, it played a limited role in the evaluation of direct colonic invasion. CT showed was eccentric wall thickening in 4 cases, large extraluminal mass in 2, and low density intraluminal mass in but one was missed on CT. CT was the most accurate modality to determine the extent of the lesion and adjacent or distant metastasis but it could be misdiagnosed as submucosal tumor if the extraluminal component is large. UGI, CT and US can be used complementary for accurate diagnosis of a duodenal cancer. US may be used as a screening tool for detecting duodenal cancer.
Adenocarcinoma*
;
Biopsy
;
Colon
;
Diagnosis
;
Duodenal Neoplasms
;
Duodenum*
;
Gastric Bypass
;
Mass Screening
;
Neoplasm Metastasis
;
Retrospective Studies
;
Ulcer
6.Comparison of Riboflavin Status between Traditional Farming Women and Commercial Farming Women in Korea.
Korean Journal of Community Nutrition 1997;2(5):701-710
this study was undertaken to compare the riboflavin status of rural women with different physical activity intensity and to determine factors influencing biochemical fiboflavin status. The study was carried out over three different farming seasons : planting (June), harvest(October) and interim(February) in two rural regions of Korea. One was a traditional farming region, the other a commercial farming region with heavier work intensity. Twenty women in the traditional region and eighteen women in the commercial region were involved. The intensity of physical activity was determined by a daily activity record. Body composition was assessed by bioelectrical impedence. Dietary riboflavin intake was measured by the food frequency method. Riboflavin biochemical status was assessed by erythrocyte glutathione reductase activity coefficient (EGR AC) and ruinary riboflavin excretion. The results from the EGR AC and urinary riboflavin excretion during the period showed the overall riboflavin status of the commercial farming women was significantly worse than that of the traditional farming women(EGR AC p<0.0001, urinary riboflavin excretion p<0.05). The traditional farming group had about 40% with risk of riboflavin deficiency, whereas the commercial farming group had about 70%. Overall mean nutrient intake was not significantly different between the two groups, however, overall mean percent lean body mass representing long term physical activity was significantly higher in the commercial farming group (<0.005). It appears that the biochemical riboflavin status of traditional farming women was significantly influenced by riboflavin intake and crude nitrogen balance while the biochemical riboflavin status of the commercial farming women was significantly influenced by riboflavin intake and percent of lean body mass over the three seasons.
Body Composition
;
Erythrocytes
;
Female
;
Glutathione Reductase
;
Humans
;
Korea*
;
Motor Activity
;
Nitrogen
;
Plants
;
Riboflavin Deficiency
;
Riboflavin*
;
Seasons
7.CT characterization of bile duct dilatation: differential disgnosis of obstructive jaundice.
Jae Hoon LIM ; Yup YOON ; Young Tae KO ; Dong Ho LEE ; Ik YANG
Journal of the Korean Radiological Society 1992;28(4):601-608
Each Disease affecting the bile ducts tends to produce characteristic pattern of billiary dilatation: recurrent pyogenic cholangitis causes dilatation and straightening of the larger(central) intrahepatic ducts ; clonorchiasis causes dilatation of the smaller (peripheral) intraahepatic ducts; and carcinoma along the extrahepatic ducts causes (proportional) dilatation and tortuosity of both larger and smaller intrahepatic ducts. To evaluate the specificity of the pattern and morphology of the dilated biliary tree on CT scancs (CT characterization) three independent radiologists who were unfamiliar with the cases were asked to classify 62 CT scans in patients with obstructive jaundice. The case population consisted of 14 cases with recurrent pyogenic cholangitis, 18 cases with clonorchiasis and 30 cases with carcinoma along the extrahepatic ducts, which were intermixed randomly. Classification was made only on the basis of CT characterization: those scans showing primary lesions i.t., stone, aggregate of flukes, or tumor mass were excluded or masked. All the scans of every case showing the extrahepatic bile duct were masked. Radiologists correctly classified 54 of the 62 cases (87%): ten of the 14 patients with recurrent pyogenic cholangitis(71%), 17 of the 18 patients with clonorchiasis(94%) and 27 of the 30 patients with carcinoma along the extrahepatic bile cucts(90%). We believe that CT characterization of bile duct dilatation is useful in the differential diagnosis of obstructive jaundice, especially when a primary pathologic lesion is not depicted in CT scans.
Bile Ducts*
;
Bile Ducts, Extrahepatic
;
Bile*
;
Biliary Tract
;
Cholangitis
;
Classification
;
Clonorchiasis
;
Diagnosis, Differential
;
Dilatation*
;
Humans
;
Jaundice, Obstructive*
;
Masks
;
Sensitivity and Specificity
;
Tomography, X-Ray Computed
;
Trematoda
8.Bile duct necrosis:Complication of transcatheter hepatic arterial embolization.
Tae Hoon KIM ; Yup YOON ; Jae Hoon LIM ; Young Tae KO ; Dong Ho LEE
Journal of the Korean Radiological Society 1993;29(5):1020-1023
Bile duct necrosis and liver abscess are rare complications after transcatheter hepatic arterial embolization (THAE) of hepatocellular carcinoma. Authors report bile duct necrosis and liver abscess occurred in 2 cases as a complication of THAE of hepatocellular carcinoma. In these two patients, lipiodol emulsion mixed with adriamycin and mitomycin was used more than three times as chemoembolic materials.
Bile Ducts*
;
Bile*
;
Carcinoma, Hepatocellular
;
Doxorubicin
;
Ethiodized Oil
;
Humans
;
Liver Abscess
;
Mitomycin
;
Necrosis
9.A STUDY ON THE BOND STRENGTH OF REINFORCED INDIRECT COMPOSITE RESINS TO DENTAL ALLOYS.
Dong Joo YOON ; Sang Wan SHIN ; yu Won SUH ; Ho Nam LIM
The Journal of Korean Academy of Prosthodontics 1999;37(5):620-639
Indirect composite resin are used as an popular effective esthetic material in prosthetic dentistry, often with metallic substructure that provides support for restorations. Recently, new indirect composite resins as a substitute of ceramic have been developed. These resins provide good esthetics, with a wide range of hue and chroma. And the flexural strength of those is in the range of 120-150MPa, which is higher than that of feldspathic ceramic, and similar tot hat of Dicor. Although it has many merits, one of the major clinical problems of composite resins is the bond failure between metal and resin due to insufficient interfacial bond strength. The purpose of this study was to evaluate shear bond strength of the reinforced indirect composite resin to dental alloys. Three different composite resin systems(Artglass . Sculpture , Targis ) as test groups and ceramic(VMK 68 ) as control group were bonded to Ni-Cr-Be alloy(Rexillium III ) and gold alloy(Dave 4). All specimens were stored at 37degrees C distilled water for 24 hours and the half of specimens were thermocycled 2000 times at temperature from 5degrees C to 60degrees C. The shear bond strengths of reinforced indirect composite resins to dental alloys were measured by using the universal testing machine, and modes of debonding were observed by stereoscope and scanning electron microscope. The results were as follows : 1. The shear bond strengths of reinforced indirect composit resins to dental alloys were approximately half those of ceramic to dental alloys(P<0.01). 2. There was no significant difference between the shear bond strength of several reinforced indirect composite resins to metal. 3. Alloy type did not affect on the shear bond strengths of resin to metal, but the shear bond strengths of ceramic to gold alloys were higher than those of ceramic to Ni-Cr alloys(P<0.05). 4. The shear bond strenghts of Artglass and Targis to gold alloys were significantly decreased after thermocycling treatment(P<0.01). 5. Sculpture showed cohesive, adhesive, and mixed failure modes, but Artglass and Targis showed adhesive or mixed failures. And ceramic showed cohesive and mixed failures.
Adhesives
;
Alloys
;
Ceramics
;
Composite Resins*
;
Dental Alloys*
;
Dentistry
;
Esthetics
;
Gold Alloys
;
Sculpture
;
Water
10.Chest radiographic findings of tuberculous pneumonia.
Seung Hye JUNG ; Dong Wook SUNG ; Yup YOON ; Jae Hoon LIM
Journal of the Korean Radiological Society 1991;27(4):535-539
No abstract available.
Pneumonia*
;
Radiography, Thoracic*
;
Thorax*