1.Pathological changes and tissue repair methods of hallux valgus
Chinese Journal of Tissue Engineering Research 2009;13(50):9958-9961
The pathological changes of hallux valgus are diversity, including adduct of metatarsus primus, increasing of the intermetatarsal angle between the first and second metatarsal bones, increasing of hallux valgus angle, dislocation of sesamoides, lost of soft tissue balancing. X-ray is the most important method to measure the pathological changes of hallux valgus. The multiformity of hallus valgus pathological changes makes manner of repairing variety. The main methods include operation on soft tissue, osseous surgery, fusion of joint and figuration of joints. The selection of the surgical methods should be individualization according to the idiographic pathological changes of hallux valgus patients.
2.Biological research evaluating the Chinese medical theory of the association of the kidney with the ears.
Journal of Integrative Medicine 2012;10(2):128-34
ABSTRACT: "Association of the kidney with the ears" is central to the traditional Chinese medical (TCM) theory of the viscera and their manifestations. Previous studies have shown that thyroxin, aldosterone, calcium and iron might be the material basis of the correlation between the kidney and the ears. Due to restriction in research techniques and methods, there has been no further progress in this research field, whose modern biological mechanisms and scientific connotations have not been explained clearly. In recent years, the progress of biological techniques and research on kidney essence provided promising opportunities for research of the association between the kidney and the ears. This article summarized the study progress of "association of the kidney with the ears" theory and posed some meaningful study thoughts. Presbycusis is a kind of degenerative disease caused by aging, which is one aspect of aging of the human body. Because aging is considered as physiological "kidney deficiency", presbycusis can be regarded as a model of "kidney deficiency" deafness. In conclusion, investigating the correlation between "kidney deficiency" and presbycusis using biotechnology systems combined with "essence of kidney", should provide a sound basis for study of the theory of the relationship between the kidney and the ears. This will provide new and valuable information for the modern biological research about the theory of visceral associations in TCM.
4.Basic and clinical research in sustained-release drug delivery systems for the treatment of malignant bone tumor
Chinese Journal of Tissue Engineering Research 2007;0(45):-
Since local chemotherapy and sustained release chemotherapy have been put forward, a number of sustained-release drug delivery systems have been developed with regard to the releasing effect in vitro and in vivo, as well as the lethal effect on the tumor cells. This study reviews the merit of sustained release chemotherapy and sustained release drug delivery system of malignant bone tumor both in vitro and in vivo.
7.Weil osteotomy for refer metatarsalgia in hallux valgus
Jianfeng XUE ; Zhongmin SHI ; Yang DONG
Orthopedic Journal of China 2006;0(09):-
[Objective]To evaluate the clinical result of Weil osteotomy for refer metatarsalgia in hallux valgus. [Method]Between 2004 and 2005, 25 feet of 17 patients with hallux valgus were treated by osteotomy at the base of the first metatarsal and Weil osteotomy of the lesser metatarsal with metatarsalgia. Weight-bearing anterior-posterior and lateral X ray were taken before the surgery and 6 weeks after surgery on follow up. The hallux valgus angle , the intermetatarsal angle between 1st and 2nd metatarsal, and length of the second metatarsal were measured on the X-ray film. AOFAS system was used to judge the clinical result of the surgery. [Result]The hallux valgus before surgery angle was 32??5.7?,after surgery it was 12.8??3.5?; the intermetatarsal angle between lst and 2nd metatarsal before surgery was 24.2??3.7?,after surgery it was 10.5??0.7?; AOFAS score was 45.6?6.9 before surgery , and 86.9?4.6 after surgery ; significant difference was found between the result. The metatarsal after Weil osteotomy was shorten by 3~8 mm, mean 4.5 mm. After surgery 18 feet had pain free, and 7 feet had a signigicant pain relief . All the patient could return to normal life without other treatment. [Conclusion ] The biomechanical changes in the foot with hallux valgus should be analyzed before surgery . Combined use of base osteotomy at the first metatarsal and Weil osteotomy at lesser metatarsal can get satisfactory clinical result in patients with sever hallux valgus and transferred refer metatarsalgia.
8.Clinical Characteristics of 100 Children with Cerebral Palsy
Dong-dong CHEN ; Bing-pei SHI ; Su-juan WANG ; Wei SHI ; Hong YANG
Chinese Journal of Rehabilitation Theory and Practice 2006;12(2):107-108
ObjectiveTo analysis the clinical characteristics and the high risk factors of children with cerebral palsy.MethodsClinical data of 100 children with cerebral palsy were retrospectively analyzed.Results51% of children were born with asphyxia, 42% were born prematurely, 39% were low birth body weight. 85.7% of children involved had mental retardation, 12% had hearing loss and 7% had visual impairment. 88% of children involved had abnormal cranial CT results and 46.1% had abnormal EEG. 50.0% of the children had abnormal brain stem auditory evoked potentials.ConclusionAsphyxia, prematurely birth and low birth body weight are high risk factors of cerebral palsy. Most of the children with cerebral palsy in this group are mental retarded.
9.Poly (L-lactic acid) absorbable pins in osteotomy for treatment of hallus valgus: A 35-case report
Wenxin LIU ; Yang DONG ; Zhongmin SHI ; Chunlin ZHANG ; Zhichang ZHANG
Chinese Journal of Tissue Engineering Research 2009;13(3):583-586
A total of 35 patients with hallus valgus (56 feet) received treatment at the Department of Orthopedics, the Sixth People's Hospital, Shanghai Jiao Tong University between January 2004 and June 2005 and were recruited into this study. These patients underwent osteotomy of proximal first metatarsal and internal fixation with poly (L-lactic acid) (PLLA) absorbable pins. All patients were followed up for 4-22 months. Excellent outcomes were found in 27 patients (44 feet) and good results in 8 patients (12 feet). The mean healing time of surgical region was 6 weeks, nonunion or delayed union was not found. There were 3 cases suffering from complications post surgery. Two of them presented with peripheral wound red swelling, considering as a result of extraneous material-caused aseptic inflammatory reaction. This phenomenon would be regressed 2-4 weeks after hydropathic compress of ethanol gauzes and timely renewal of dressings. There was 1 case who suffered from protrution of absorbable pin 1 week after fixation and received reposition and plaster fixation. Bone displacement and nonunion were not found. This complication maybe results from excessively large bone pore due to shaking of electrodrill, which leads to loosening of absorbable pins.
10.MRI diagnosis of ejaculatory duct obstruction
Yan GUO ; Yaoping SHI ; Dong YANG ; Huanjun WANG ; Bitao PAN
Chinese Journal of Radiology 2012;46(7):633-635
Objective To explore the MRI features of ejaculatory duct obstruction.Methods During January 2003 to Dccember 2010,transrectal ultrasonography (TRUS) was performed for 106 patients and underwent surgical treatment for ejaculatory duct obstruction.Among them,16 patients underwent MRI examination.The MRI features of ejaculatory duct obstruction in these patients were summarized.Results Ejaculatory duct cysts,ranging in size from 4 mm ×4 mm ×7 mm to 4 mm ×4 mm ×9 mm and locating in the paramedian line,were detected in 5 of the 16 patients; ejaculatory duct dilation located in the paramedian line was detected in 7 patients,with the internal diameter of 5 to 30 mm. After contrast injection,significant enhancement of the wall of the ejaculatory duct was observed in 2 patients.Mullerian duct cysts complicated with dilated ejaculatory duct and seminal vesicles were detected in 4 patients,in whom the cysts were located in the median line,ranging in size from 4 mm × 5 mm × 6 mm to 34 mm×35 mm ×44 mm,with inverted teardrop shaped pointing toward the seminal colliculus.ConclusionThe most common MRI features of ejaculatory duct obstruction are ejaculatory duct dilation and ejaculatory duct cysts.