1.The Care of Patients with Paralysis Caused by Thoracic , Thoraco
The Journal of the Korean Orthopaedic Association 1989;24(6):1678-1685
In recent years, the rate of the spine fracture tends to be on the increase year by year as rate of traffic and industrial accidents are increased. 111 patients with paralysis caused by thoracic, thoracolumbar, lumbar spine injuries were evaluated from January, 1979 to December, 1988 in our study. 1. In patients with paralysis caused by thoracic, thoracolumbar, lumbar spine injuries, most common site of injuries was “thoracolumbar junction” (47.7%) and most common cause was “fall down” (48.7% ). 2. “Burst fracture” was most common type of injuries which were classified by 3-column concept according to Denis & McAfee(52.3%) 3. In early 1980's the operation was performed with Harrington rod, anterior decompression & AIF, posterior decompression & PIF and from 1984, mainly Luque sublaminar wiring, and in 1988, SSI was commonly used. 4. There was no difference in neural recovery between conservative and operative treatments. 5. There was statistic significance in the incidence of complications between conservative and operative treatments(p <0.05). 6. The more severe neurologic damage at injury, the higher incidence in complication(p<0.05). Therefore, although there was no significant difference in neural recovery between conservative and operative treatments in the care of paralysed patients caused by thoracic, thoracolumbar, lumbar spine injuries, rigid internal fixation and rapid mobilization can be recommended for decreasing complications by prologed bed rest and active rehabilitation.
Accidents, Occupational
;
Bed Rest
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Decompression
;
Humans
;
Incidence
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Paralysis
;
Rehabilitation
;
Spine
2.Immunohistochemical Study of S-100 Protein in Salivary Gland Tumors.
Hyun Yeung KANG ; Dong Wook RYANG ; Joo Yong YOO
Korean Journal of Pathology 1986;20(4):427-434
An immunohistochemistry for S-100 protein by biotin avidin system technique was done to evaluate the existence and distribution pattern of S-100 protein positive cells in various obtained were as follows. 1) Positive immunostaining for S-100 protein was observed in myoepithelial cell, serous acinar cell and nervous bundle in normal salivary gland. 2) Strong immunoreactivity for S-100 protein was shown in plemorphic adenoma, which was localized not only in myoepithelial cord or sheets of epithelial portion but also in chondrocytes, stellate cells of myxoid stroma and in squamous keratin pearl of mesenchymal metaplastic foci. 3) The S-100 protein was demonstrated in the tumor cells of tubular adenoma, acinic cell tumors and in epidermoid area of mucoepidermoid tumors. 4) Immunoreactivity for S-100 protein, however, was not found in the tumor cells of adenoid cystic carcinoma and adenolymphoma except for stroma reticulum cells. 5) Intensity of positive reaction for S-100 protein varied from cell to cell: Some had intense immunoreactivity, whreas others were only weakly positive or completely negative, even in myoepithelial cell nest of the same pleomorphic adenoma.
3.Double-Layered Lateral Meniscus: A Case Report
Chung Nam KANG ; Dong Wook KIM ; Seung Hyun HWANG
The Journal of the Korean Orthopaedic Association 1996;31(6):1307-1310
Many types of meniscal anomalies were reported. Authors found a double-layered lateral meniscus, with one meniscus overlying another. The 39-year old male patient had torn medial and lateral menisci. We performed partial medial and lateral meniscectomy, and incidentally found that lateral meniscus was double-layered. It was characteristic that the upper small accessory meniscus was firmly connected from the posterior horn to middle segments of the lower main meniscus along its peripheral edge. We left it alone. The symptoms were gone, So, it was thought that this anomaly was not related to the patient's symptoms.
Animals
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Horns
;
Humans
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Male
;
Menisci, Tibial
4.Fusarium Fruit Rot of Citrus in Jeju Island.
Jae Wook HYUN ; Seong Chan LEE ; Dong Hwan KIM ; Sang Wook KO ; Kwang Sik KIM
Mycobiology 2000;28(3):158-162
Twenty-three isolates of Fusarium spp. were obtained from decayed citrus fruits in the fields and storages in 1998-1999. Of them, six and five isolates belonged to F. proliferatum and F. moniliforme, respectively, which were the most common. F. solani and F. sambucinum had each two isolates, F. equiseti had one isolate and seven isolates were unidentified. They produced symptoms of two types in pathogenicity test: those with leathery, beige to light or dark brown, and sunken lesions without surface mycelium (type-1) and those with lesions covered with white, beige or pink surface mycelium (type-2). Four of six isolates identified to F. proliferatum and two unidentified isolates produced type-1 lesions, and all isolates identified to F. moniliforme, F. solani, F. sambucinum, F. equiseti and five unidentified isolates produced type-2 lesions.
Citrus*
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Fruit*
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Fusarium*
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Mycelium
;
Virulence
5.Ganglion Cyst of the Posterior Cruciate Ligament: A Case Report.
Dong Wook CHEON ; Jin Wook JUNG ; Keun Il LEE ; Hyun Min KIM
Journal of the Korean Knee Society 1997;9(2):242-244
This case report draws attention to the possibility of symptomatic and asymptomatic intraarticular ganglion cyst which was situated adjacent to the insertion sites of the anterior or posterior cruciate ligament. In many reports and our case, MR imaging is recommended as the modality of choice in diagnosing method and the cyst, if encountered, is successfully treated with arthroscopie technique. We report one case of symptematic ganglion cyst of the posterior cruciate ligament with review of literatures.
Ganglion Cysts*
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Knee
;
Magnetic Resonance Imaging
;
Posterior Cruciate Ligament*
6.A clinical analysis of the marjolin's ulcer.
Dong Ik CHOI ; Do Hyun KIM ; Jong Wook LEE ; Young Chul JANG ; Dong Chul KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1998;25(6):1115-1120
Marjolin's ulcer is a malignant degeneration of cicatrical tissue, especially in chronic burn scar. Since the first description by Jean Nicholas Marjolin(1828), many studies for Marjolin's ulcer have been performed and reported. From 1985 to 1997, we experienced 20 cases in 14 patients diagnosed as Marjolin's ulcer clinically, and we analysed malignant transformation rate, induction period of Marjolin's ulcer and prevention of Marjolin's ulcer, etc. The results are summarized as follows. 1) The sex distribution was predominant in male(64.3%). 2) The most common cause of injury was flame burn(78.6%). 3) The mean age at the time of diagnosis was 45.6 years and the average lag period was 20.6 years. 4) The pathologic types of Marjolin's ulcer were squamous cell carcinoma(57.2%), followed by dyspasia(28.6%), acnthosis and hyperkeratosis(14.2%). 5) The locations of ulcers were frequently on the lower extremity(42.9%), followed by upper extremity(35.7%) and trunk (21.4%). 6) The lymph node involvements were 3 patients out of the 8 patients who were confirmed as squamous cell carcinoma. 7) The modalities of treatment were skin graft (18 cases, 12 patients), myocutaneous flap(1 case, 1 patient), fasciocutaneous flap(1 case, 1 patient).
Burns
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Carcinoma, Squamous Cell
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Cicatrix
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Diagnosis
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Humans
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Lymph Nodes
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Sex Distribution
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Skin
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Transplants
;
Ulcer*
7.Tufted Angioma:Clinicopathologic Surveys and the Response to Intralesional Steroid.
Dong Hyun KIM ; Sung Nam CHANG ; Soo Il CHUN ; Dong Sik BANG ; Wook Hwa PARK
Annals of Dermatology 2002;14(1):22-27
BACKGROUND: Tufted angioma is an uncommon slowly progressive vascular tumor found typically in infants and young children with characteristic histologic findings, so called "cannonball" appearance. OBJECTIVE: The purpose of this study was aimed to investigate the clinical and histopathological characteristics of tufted angioma and the response to intralesional steroid. METHODS: Clinical information of 10 patients with tufted angioma diagnosed in Severance hospital and Pundang CHA hospital from 1983 to 1999 was obtained from the medical records and clinical follow-ups. We re-evaluated 10 biopsy specimens obtained from them with routine H&E staining. RESULTS: Five male and five female patients were included. In 9 patients the lesion appeared before 2 months of age. Four had a lesion at birth. The thigh was the most common site. The clinical symptoms were diverse, but characteristically tenderness was present in most cases. In all the patients the lesions had a tendency to spread progressively. Microscopically, numerous, distinct, variably sized, tightly packed capillary and endothelial cellular lobules were scattered in the dermis. There were characteristic semilunar spaces adjacent to the capillary tufts. Six patients received intralesional triamcinolone. This treatment was found to be effective in 5 patients who experienced remarkable improvement. The improved cases had similar histologic findings which were composed of cellular mass more than lumen formation. We classified our specimens into two categories, one with more cellular mass and the other with more lumen formation in relative proportion. The former was different from the latter in that it had more solid appearance and more definite margin. And we realized that it was useful to divide into these two categories since its response to treatment could be different. CONCLUSIONS: Tufted angioma is a relatively uncommon disease with characteristic histopathologic findings. It seems not to regress spontaneously. So early treatment is required to pre-vent further spreading up to the extent. We treated 6 patients with intralesional injection of triamcinolone and 5 patients experienced marked improvement which had more cellular mass more than lumen formation histopathologically.
Biopsy
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Capillaries
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Child
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Dermis
;
Female
;
Follow-Up Studies
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Hemangioma
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Humans
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Infant
;
Injections, Intralesional
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Male
;
Medical Records
;
Parturition
;
Thigh
;
Triamcinolone
8.Systemic Scleroderma in Childhood.
Wook Hwa PARK ; Tae Hyun PARK ; Kyung Deuk PARK ; Dong Sik BANG ; Soo Il CHUN
Korean Journal of Dermatology 1995;33(1):183-187
The onset of systemic scleroderma in the first. decade of lif occurs in less than 1.5% of instances. Systemic sclerodrma in childhood have been characterized by less severe visceral involvement and a benign course We report a boy, aged 7 years, with a history of Raynaid; phenomenon and dysphagia. He had a mask-like face, flexion contracture of hands and knee joints, digital pitting scars, ichthyosiform skin change on leg and hyperpigrnented induration on all extremities and trunk. Antinuclear antibodies were positive in nucleolar type and Scl-70 antiocy was also present. On radiologie study, the pattern of reflux esophagitis and resorption of the listal ends of all phalanges were nated. Histopathological findings were compatible with sclerodma. He was treated with Penicillamine-D and oral corticosteroic with good improvernent.
Antibodies, Antinuclear
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Cicatrix
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Contracture
;
Deglutition Disorders
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Esophagitis, Peptic
;
Extremities
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Hand
;
Humans
;
Knee Joint
;
Leg
;
Male
;
Scleroderma, Systemic*
;
Skin
9.Intracranial Encephalocele: an autopsy case of anterior basal type.
Hyun Wook KANG ; Je G CHI ; Tae Dong PARK ; Hum Rae PARK
Korean Journal of Pathology 1988;22(4):500-504
Encephalocele is a relatively rare congenital anomaly which is classified into occipital, parietal, anterior syncipital and anterior basal type regarding to the protrusion site through the bony defect of the skull. Anterior basal type of encephalocele is important in view of it's pathogenesis as well as diagnostic difficulty because of invisibility on external appearance. We have experienced a case which could be best fit to anterior basal encephalocele. This type of encephalocele is extremely rare. This report deals with a case of deadborn of 34 weeks of gestation with body weight of 2400gm and head circumference of 32 cm. There was no evidence of protrusion of brain on external examination. On autopsy the normal brain structure was compressed by abnormal mass of brain with normal consistency which was found in the petrous portion of the parietal area and covered partly by the dura. In this case, there were another associated anomalies, such as atrophy of the left optic nerve, hemihypoplasia of the left mandible, patent ductus arteriosus, bilateral hydrocele, and Meckel's diverticulum.
10.Correlation of Nitric Oxide Concentrations in Follicular Fluid with the Ovarian Response as well as the Age in Women Undergoing Controlled Ovarian Hyperstimulation.
Wook Hyun KWON ; Dong Hyung LEE ; Kyu Sup LEE
Korean Journal of Obstetrics and Gynecology 2005;48(4):996-1003
OBJECTIVE: To elucidate the correlation of nitric oxide (NO) concentrations in follicular fluid (FF) with the ovarian response as well as the age in women undergoing controlled ovarian hyperstimulation (COH). METHODS: This study was performed in 72 cycles of whom underwent COH for in vitro fertilization at infertility clinic of Changwon Hanmaeum Hospital and Pusan National University Hospital from Aug., 2003 to Dec., 2003. Each FF was collected at the oocyte retrieval and NO concentrations in FF were assessed. We analyzed the correlation of NO concentrations in FF with the ovarian response as well as the age in women undergoing COH. RESULTS: Among 72 cycles, the clinical pregnancy rate was 37.5% (27cycles). There were no significant differences in patient's age, ampules of gonadotropins used, estradiol level on the day of hCG administration, the number of oocytes retrieved, and fertilization rate between pregnant and nonpregnant groups. However, negative correlation was found between the follicular size and NO concentrations in FF. No significant correlation was found between age and NO concentrations in FF. Comparing NO concentrations in FF between pregnant and nonpregnant women by age, NO concentrations in FF were higher at nonpregnant women, significantly those of them more than 40 years old. CONCLUSION: These results suggest that NO concentrations in FF cannot be a marker for the ovarian response, and have no correlation with all parameters of COH including patients' age with exception for the follicular size.
Adult
;
Busan
;
Estradiol
;
Female
;
Fertilization
;
Fertilization in Vitro
;
Follicular Fluid*
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Gonadotropins
;
Gyeongsangnam-do
;
Humans
;
Infertility
;
Nitric Oxide*
;
Oocyte Retrieval
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Oocytes
;
Pregnancy Rate