A 17-year-old male had a coin sized, follicular plaque on the glabella for 3 months. Histopathologic examination revealed reticular degeneration in the pilosebaceous follicles and amorphous homogenous materials between the degenerated cells. Alcian blue and toluidine blue stained the material as blue and metachromatically purple, respectively. The material was subsequently confirmed as acid mucopolysaccharide. Two months after the initial visit, the lesion showed a tendancy to heal spontaneously. According to the data obtained, the case was considered as an acute benign form of follicular mucinosis.
Adolescent ; Alcian Blue ; Humans ; Male ; Mucinosis, Follicular* ; Numismatics ; Tolonium Chloride

PURPOSE: Venous thromboembolism (VTE) is a common life-threatening illness with significant morbidity and mortality rates. In recent years, the incidence of VTE has gradually increased in Korea. In this study, we evaluated the current trends in the management of acute deep vein thrombosis (DVT) in Korea. MATERIALS AND METHODS: A 20-item questionnaire was prepared and sent to 48 members of the Korean Society for Vascular Surgery. Each member worked in a different hospital. Twenty-two members participated in this study. RESULTS: The vascular surgery departments were primarily responsible for managing DVT. Ultrasound and computed tomography (CT) venography were chosen as the most common initial diagnostic tools. Eighty-two percent of participants routinely used the coagulation factor assay. Thrombolysis and inferior vena cava (IVC) filter insertion were performed mainly in the radiology departments. Seventy-seven percent of participants performed thrombolysis only if the thrombus age was less than 21 days. During thrombolysis, IVC filter was routinely inserted by 50% of respondents and removed within 14 days by 64% of respondents. Nearly all participants followed the 2012 American College of Chest Physicians guidelines for anticoagulation therapy. CONCLUSION: The majority of Korean vascular surgeons followed the guidelines. However, CT was frequently used. Thrombolysis and IVC filter insertion were more frequently performed than recommended by the guidelines.
Blood Coagulation Factors ; Surveys and Questionnaires ; Incidence ; Korea ; Mortality ; Phlebography ; Thorax ; Thrombosis ; Ultrasonography ; Veins ; Vena Cava, Inferior ; Venous Thromboembolism ; Venous Thrombosis*

BACKGROUND: The clinical study of Sweets syndrome has never been reported in Korea. OBJECTIVE: The purpose of this study was to elucidate the clinical observations and associated diseases of Sweets syndrome. METHODS: During a 5-year-period from Jan. 1990 to Dec. 1994, 32 patients were evaluated in regard to age incidence, sex ratio, location of skin lesions, and associated diseases. RESULTS & CONCLUSIONS : 1, The age distribution was in the range of 21-70 years. Most patients were between 31 to 40 years of age. There were 12 male patients and 20 female giving a sex distribution of 1.7: 1 ratio in favor of the fernale. 2. The most cornmon site of iavolvement was the arm(37.5%). 3. ESR was increased in 21 patients(65.6%) and leukocytosis was present in 13 patients(40.6) 4. The most common associated disease was Behcets disease(31.2%). 5. Steroids were used mos frequently for treatment of Sweets syndrome with 12 patients(37.5%). Recurrence occurred in 7 patients(21.9%). The results show that the iniidence of Sweets syndrome in men in Korea is not as rre as was previously thought and tfiat there are many associated diseases especially Behcets disease.
Age Distribution ; Female ; Humans ; Incidence ; Korea ; Leukocytosis ; Male ; Recurrence ; Sex Distribution ; Sex Ratio ; Skin ; Steroids ; Sweet Syndrome

The development of carcinoma in a subcutaneous dermoid cyst is a rare event. We report a 54-year-old Korean woman in whom excised subcutaneous dermoid cyst showed squamous cell carcinoma in the cyst wall.
Female ; Humans ; Cysts

BACKGROUND: Morphologic characteristics of the human embryonic and fetal periderm according to body region are not very clearly defined. OBJECTIVE: We have tried to Clarify the sequential development of periderm regionally. METHOD: Skin samples were obtained from 12 human embryos and fetuses ranging from 4 to 23 estimated gestational ages(EGA) and divided regionally into scalp, face, back. abdomen, thigh and sale. Specimens were observed by scainning with an electron microscope. RESULTS: Human embryonic end fetal periderm show distinct morphologic changes as follows along its own sequence of development flattened surface, elevated surface, fiormation of incomplete bleb. single bleb stage, multiple-complex bleb stage, formation of regressinjg bieb. Then towards the end of the second trimester, most of thieperidermal cells are completely regressed. Regional variation in peridermal development is not evide!nt during the embryonic period, but earlier development is apparent in the sole, face and scalp especially in the sole compared to other areas during the late first snd second trimester after EGA 9 weeks. CONCLUSION: The periderm, which can be seen only in embryonic and fetal epidermis, shows distinct sequential developmental changeis with regional variation.
Abdomen ; Blister ; Body Regions ; Commerce ; Embryonic Structures ; Epidermis ; Female ; Fetus ; Humans* ; Pregnancy ; Pregnancy Trimester, Second ; Scalp ; Skin ; Thigh

Polydactyly is the most common congenital anomaly of the upper limb. Polydactyly is classified as preaxial polydactyly(thumb), central polydactyly(index, middle and ring fingers), and postaxial polydactyly(little finger) by the site of the extra digit. A 3-day-old female newborn had a 1.5 * 1.0cm sized flesh color ed pedunculated sac like mass on the proximal phalanx of her right thumb since birth. A roentgenogram on the hand revealed no bony abnormalities of the digit and the mass contained no bony structures. The stalk of the mass was cut by the CO2 laser. On histopathological examination, a cartilage structure was found in the loosely arranged, edematous dermis and the overlying epidermis was flattened. The clinical and histological findings support the diagnosis of preaxial polydactyly. We report this interesting case of preaxial polydactyly with a review of the literature.
Cartilage ; Color ; Dermis ; Diagnosis ; Epidermis ; Female ; Hand ; Humans ; Infant, Newborn ; Lasers, Gas ; Parturition ; Polydactyly* ; Skin* ; Thumb ; Upper Extremity

Squamous cell carcinoma in chronic osteomyelitic foci is uncommon malignant tumor although well documented. This article deals with clinical study of 9 cases of squamous cell carcinoma arising in chronic osteomyelitic foci during past 9 years from April 1962 to March 1969 at the Dept. Orthopedic Surgery, Taegu Presbyterian Hospital. The diagnosis was confirmed by clinical symptoms, history, tissue and lymph node biopsy. Brief analysis of age and sex distribution, symptoms, physical findings and clinical management were recorded and summarized as follow: 1). This tumor may occur in any age group but all reported cases were after the age of 30. 2). Only 1 outof 9 cases was female. 3). The common clinical manifestations at the time of admission were draining sinus with foul odorous discharge, fungating mass and enlargement of regional lymph node. 4). More than 80% of our series occurred in the lower extremity, tibia acouting 55.6%. 5). 6 casses had epen fracture and duration of osteomyelitis was 28 years in average. 6). Biopsy included tissues from all portions of sinuses, a fungating mass and the tissues from the marrow space in case of deep extension. 7). The choice of treatment consisted of early adequate amputation or radical resection of the focus and irradiation.
Amputation ; Biopsy ; Bone Marrow ; Carcinoma, Squamous Cell ; Clinical Study ; Daegu ; Diagnosis ; Epithelial Cells ; Female ; Humans ; Lower Extremity ; Lymph Nodes ; Odors ; Orthopedics ; Osteomyelitis ; Protestantism ; Sex Distribution ; Tibia

PURPOSE: Conventional intravenous nutrition has been given as a solution of amino acids combined with dextrose and a separate line delivering a lipid emulsion. This technique was unsatisfactory, however, because of difficulties in managing technical and metabolic complications. Since the first clinical use of a single solution containing all the necessary nutrients was introduced in 1976, the total nutrient admixture (TNA) system has been used. However, despite the numerous advantages of this TNA system, it has not been used worldwide because of an assumption about unstability of this admixture. This study was conducted to compare the physical stability of TNA systems using two different 2 commercially available amino acid solutions and fat emulsions. METHODS: Each group contained 600 ml of 20% dextrose, 250 ml of 10% amino acid solution, 250 ml of 10% fat emulsion, 0.2 ml of heparin, and 20 ml of electrolyte solution was investigated for 7 days while being stored 4oC and at ambient temperature. The stabilities of these admixtures were compared by noting changes in macroscopic appearance, pH, osmolarity, Zeta-potential, peroxide value, particle size and distribution, and fat composition. RESULTS: When an amino acid solution containing P 2 was used, a supernatant yellow band was observed from the 3rd day at ambient temperature. The pH and peroxide value also showed significant changes, but these changes did not exceed the product-specifications. When an amino acid solution without P 2 was used, no significant change was observed. CONCLUSION: TNA systems are physically stable at 4oC temperature for at least 7 days, but TNA systems prepared with amino acid solution containing P 2 are not stable at ambient temperature from the 3rd day. On the other hand, TNA systems prepared with an amino acid solution without P 2 are stable at ambient temperature for 7 days. Various commercially available fat emulsions containing 10% soybean oil did not affect the stability of TNA systems.
Amino Acids ; Emulsions ; Glucose ; Hand ; Heparin ; Hydrogen-Ion Concentration ; Osmolar Concentration ; Parenteral Nutrition ; Particle Size ; Soybean Oil

The primitive erythroblasts in 21 cases of embryonic hearts from 4 to 9 weeks of gestation were studied with a light microscope. The nuclear diameter, the motosis, and the loss of nuclei of the primitive erythoblasts were analyzed quantitatively. The results obtained were as follows. 1. At 4 weeks of gestation, the blood cells consisted of proerythroblasts, along with basophilic polychromatophilic primitive erythroblasts. The nuclear diameter ranged from 3.20 µm to 9.20 µm, but the main range was from 4.20 µm to 6.00 µm. It was revealed that 9.50% had diameter of more than 6 µm. 2. At the fist half of the 7 week gestation when hepatic hemopoiesis developed, the blood cells consisted of basophilic, polychromatophilic, and eosinophilic erythroblasts. Cells of more than 6 µm in nuclear diameter were about 1.10% and thereafter gradually disappeared. The range of the nuclear diameters was from 2.60 µm to 7.00 µm, while a range from 3.40 µm to 5.20 µm wqs the main. The proportion of cells less than 4 µm in nuclear diameter was 39.58% and thereafter rapidly increased. 3. From the second half of 7 weeks to 9 weeks of gestation, the erythrocytes originating from hepatic hemopoiesis increasingly replaced the circulating primitive erythroblasts, which became mature during this time. The erythrocytes showed 72.88% at 9 weeks of gestation. The proportions of cells less than 4 µm in nuclear diameter in the first and second haIves of 8 weeks and 9 weeks were 52.73%, 80.02%, and 89.09%, which represented the rapid destruction of nuclei. 4. Mitosis in the primitive erythroblasts occurred principally up to the early 6th weeks, and very weakly at 8 weeks. 5. As the crown-rump length increased, the average nuclear diameter decreased very significantly (P<0.01, y=-0.2811X + 0.3171). The results suggest that distrilbution of the nuclear diameter, the maturity, the rate of nuclear loss, and the mitotic figure offer credible data for estimating embryonic age.
Basophils ; Blood Cells ; Crown-Rump Length ; Embryonic Structures* ; Eosinophils ; Erythroblasts* ; Erythrocytes ; Heart ; Humans* ; Mitosis ; Pregnancy

No abstract available.
Adolescent ; Humans ; Personal Satisfaction ; Smoke* ; Smoking*