1.The frequencies of unexpected antibodies in transfusion candidates and selection of cross-matching method.
Hyun Ok KIM ; Dong Il WON ; Oh Hun KWON
Korean Journal of Blood Transfusion 1993;4(1):35-41
No abstract available.
Antibodies*
2.Sebaceous Hyperplasia Treated with Isotretinoin.
Won Hyoung KANG ; Dong Hoon SONG ; Soo Il CHUN
Korean Journal of Dermatology 1986;24(1):133-135
We present herein a case of sebaceous hyperplasia in a 55-year-old male, who showed multiple asymptomatic yellowish papules on the forehead and the cheeks. Histopathologic examination of a papule revealed numerous sebaceous lobules grouped around several enlarged sebaceous ducts. Three weeks of oral administration. of isotretinoin 40 mg per day brought marked improvement.
Administration, Oral
;
Cheek
;
Forehead
;
Humans
;
Hyperplasia*
;
Isotretinoin*
;
Male
;
Middle Aged
3.Spotted Grouped Pigmented Nevi.
Soo Il CHUN ; Dong Hoon SONG ; Won Hyoung KANG
Korean Journal of Dermatology 1986;24(4):554-558
We experienced three cases of non-giant congenital nevus. They showed zosteriform or heart-shaped grouping of pigmented papules which were pierced by hairs. Histopathologic examination disclosed nevus cell infiltration in and around hair follicles and in the upper two thirds of reticular dermis. We would like to report these cases as follicle-centered spotted grouped pigmented nevi.
Dermis
;
Hair
;
Hair Follicle
;
Nevus
;
Nevus, Pigmented*
4.Association between Schizophrenia and the T102C Polymorphism of the 5-HT2A.
Min Soo LEE ; Jong Won NAM ; Dong Il KWAK
Journal of the Korean Society of Biological Psychiatry 1998;5(2):215-218
The 5-HT2A receptor is of great interest for research into schizophrenia and psychopharmacology in light of the observation that schizophrenic patients has 5-HT cortical-subcortical imbalance and atypical antipsychotic clozpine has 5-HT2A antagonists properties. An significant association between schizophrenia and the T102C polymorphism of the gene for 5-HT2A receptor has been reported. In this study, we investigated an association between schizophrenia and the T102C polymorphism of the gene for 5-HT2A receptor in Korean schizophrenic patients. The subjects consisted of 139 schizophrenic patients and 88 normal controls. Genomic DNA was amplified by PCR and digested with MsPI. The uncutt product identified allele 1(nucleotide sequence TCT) ; digested products of 216bp and 156bp identified allele 2(nucleotide sequence TCC). The allele frequencies and the genotypic distribution of 5-HT2A receptor gene were not significantly different between schizophrenic patients and normal controls. Since allele frequencies of the T102C polymorphism may differ between individuals of different ethnic backgrounds, it needs to be conducted in an advanced research.
Alleles
;
DNA
;
Gene Frequency
;
Humans
;
Polymerase Chain Reaction
;
Psychopharmacology
;
Receptor, Serotonin, 5-HT2A
;
Schizophrenia*
;
Serotonin
;
Serotonin 5-HT2 Receptor Antagonists
5.The Usefulness of the UBC(TM)(Urinary Bladder Cancer) Test for Screening of Transitional Cell Carcinoma of the Bladder in Patients with Hematuria.
Korean Journal of Urology 2004;45(1):14-18
PURPOSE: A new quantitative tumor marker, based on the combined measurement of urinary fragments of cytokeratins 8 and 18, namely the urinary bladder cancer antigen(UBC(TM)) test, has been proposed for the detection of bladder transitional cell carcinoma(TCC). We evaluated the diagnostic efficacy of UBC(TM) test in comparison with that of urinary cytology to establish UBC(TM) test for the diagnosis of TCC. MATERIALS AND METHODS: One-hundred ninety-six patients with hematuria were included in this study. Forty patients were diagnosed histologically as TCC by transurethral resection or radical cystectomy(group A), while the others had various benign urinary tract conditions(group B). RESULTS: UBC(TM) levels were significantly different between groups A (1851.39+/-4627microgram/l) and B (19.28+/-107.03microgram/l) (p<0.001). Sensitivity for diagnosis of TCC was 89.7%(36/40) in UBC(TM) test and 45%(18/40) in cytology(p<0.05). Specificity for diagnosis of TCC was 84.6%(132/156) in UBC(TM) test and 100%(156/156) in cytology. UBC(TM) test was significantly more sensitive than cytology in stage Ta(85.7% vs. 0%, p<0.05), T1 tumors(89.4% vs. 31.5%, p<0.05), and in Grades 1(83.3% vs. 25%, p<0.05) and 2(90.4% vs. 52.3%, p<0.05) tumors. UBC(TM) test was more sensitive in higher Grade(83.3% in Grade 1, 90.4% in Grade 2 and 100% in Grade 3). CONCLUSIONS: In comparison with urinary cytology, UBC(TM) test could be a valuable marker for diagnosis of TCC in patients with early stage and low grade TCC. Therefore, UBC(TM) test in association with cytology may be useful as a screening test for TCC of the bladder.
Carcinoma, Transitional Cell*
;
Diagnosis
;
Hematuria*
;
Humans
;
Keratins
;
Mass Screening*
;
Sensitivity and Specificity
;
Urinary Bladder Neoplasms
;
Urinary Bladder*
;
Urinary Tract
6.A Case of Leflunomide Induced Vasculitis.
Kyu LEE ; Dong Gyu KIM ; Ji Hyun OH ; Dong Il LEE ; Choong Won LEE
The Journal of the Korean Rheumatism Association 2004;11(4):459-460
No abstract available.
Vasculitis*
7.Species and antimicrobial susceptibility of enteropathogenic bacteria isolated in 1986-1991.
Kwang Soo PARK ; Kye Won LEE ; Dong Il WON ; Kyung Won LEE ; Woon Seob JUNG ; Oh Hun KWON
Korean Journal of Infectious Diseases 1993;25(3):221-229
No abstract available.
Bacteria*
8.A case of myxoid leiomyosarcoma of uterus.
Dong Hoon HWANG ; Yeon Sook LEE ; Won Il PARK ; Yoon Ho LEE ; Yui Jung KIM ; Chan Il PARK
Korean Journal of Obstetrics and Gynecology 1993;36(7):2058-2062
No abstract available.
Leiomyosarcoma*
;
Uterus*
9.Anomalous Position of the Gallbladder.
Young Tae KO ; Dong Ho LEE ; Joo Won LIM ; Tae Il HAN ; Yup YOON
Journal of the Korean Radiological Society 1994;31(6):1107-1112
PURPOSE: To determine the significance of anomalous position of the gallbladder. MATERIALS AND METHODS: Sixteen patients with anomalous position of the gallbladder were evaluated for analysis. The diagnosis was confirmed by ultrasonography(15 patients) and oral cholecystography(1patient). Among those, six patients underwent CT scan and a patient had 99mTc-DISIDA scan. The images were analysed with respect to the location of the GB and configuration and associated abnormality of the liver and hepatobiliary systems. Medical records of each patient were also reviewed. RESULTS: Among 16 patients having an anomalous position of the gallbladder, nine had retrodisplaced gallbladder, four had left-sided gallbaldder, two had suprahepatic gallbladder, and one had floating gallbladder. Except for one patient, fifteen had abnormality in the liver such as focal atrophic or hypoplastic change and liver cirrhosis. Intrahepatic stones were demonstrated in 6 patients. CONCLUSION: Our results showed that anomalous position of the gallbladder was commonly associated with atrophy or hypoplasia of the liver rather than congenital in origin. The possiblity of an anomalous location of gallbladder should be kept in mind when GB is not in its normal location.
Atrophy
;
Diagnosis
;
Gallbladder*
;
Humans
;
Liver
;
Liver Cirrhosis
;
Medical Records
;
Technetium Tc 99m Disofenin
;
Tomography, X-Ray Computed
10.A Case of Cutaneous Larva Migrans.
Joo Won KIM ; Dong Jun KIM ; Il Hwan KIM ; Hae Jun SONG ; Chil Hwan OH
Korean Journal of Dermatology 1999;37(3):423-426
A 34-year-old woman presented with several intensely pruritic erythematous serpiginous thread-like skin lesions which began as a small papule on the epigastrium 4 months prior to her visit and was migrating to the left chest area. The laboratory examination showed eosinophilia and the total serum IgE level was slightly increased. Histopathologic examination revealed a pustular burrow in the epidermis with a larva-like cystic lesion apart from the burrow in the epidermis. The patient was treated with topical 10 % albendazole cream 3 times daily for 1 week without recurrence for 22 months up to now. We thought this was a rare case which was confirmed by a skin biopsy showing larva in the epidermis.
Adult
;
Albendazole
;
Biopsy
;
Eosinophilia
;
Epidermis
;
Female
;
Humans
;
Immunoglobulin E
;
Larva
;
Larva Migrans*
;
Recurrence
;
Skin
;
Thorax