1.On the Quality-Based Education for Modern Medical Students from the Physician-Patient Relationship
Yanhong FAN ; Hui DONG ; Haichang WANG
Chinese Medical Ethics 1995;0(02):-
By studying the physician-related factors in physicianpatient relationship,authors put forwards that excellent medical skill,good medical ethics,favorable communication ability,and adequate knowledge on relevant legal regulations are four key points to handle the physician-patient relationship harmoniously.This article will supply reference from the above aspects for the all-around quality-based education for medical students.
2.Effect of Music Electroacupuncture on Perifocal Ferric Ions and Neuronal Apoptosis Percentage and the Brain Water Content in Rats with Acute Cerebral Hemorrhage
Chunlan XU ; Fan WANG ; Hongsheng DONG
Shanghai Journal of Acupuncture and Moxibustion 2017;36(7):840-845
Objective To investigate the effect of music electroacupuncture on perifocal ferric ions and neuronal apoptosis and the brain water content in rats with acute cerebral hemorrhage and explore the mechanism of its action on acute cerebral hemorrhage.Methods One hundred and twenty-eight healthy adult male Wister rats were randomized to normal, model, electroacupuncture and music electroacupuncture groups. In each group, four time points of 6 hrs, 24 hrs, 3 days and 7 days were set up, eight rats each time point. A rat model of acute cerebral hemorrhage was made using collagenase. In the electroacupuncture and music electroacupuncture groups, point Baihui was connected to the anode and point Taiyang to the cathode, 2 voltage was used as a selection parameter and electroacupuncture lasted 30 min. Intracerebral perifocal ferric ions and neuronal apoptosis and the brain water content were measured at four time points of 6 hrs, 24 hrs, 3 days and 7 days after model making.Results Intracerebral ferric ion content was higher in the model, electroacupuncture and music electroacupuncture groups of rats than in the normal group at 6 hrsafter model making (P<0.05), lower in the electroacupuncture and music electroacupuncture groups than in the model group at 24 hrs, 3 and 7 days after model making (P<0.05) and lower in the music electroacupuncture group than in the electroacupuncture group at 3 and 7 days after model making (P<0.05). Intracerebral neuronal apoptosis was higher in the model, electroacupuncture and music electroacupuncture groups of rats than in the normal group at 6 hrs after model making (P<0.05) and lower in the music electroacupuncture group than in the electro- acupuncture group at 7 days after model making (P<0.05). The brain water content was higher in the model, electro- cupuncture and music electroacupuncture groups of rats than in the normal group at 6 and 24 hrs after model making (P<0.05), lower in the electroacupuncture and music electroacupuncture groups than in the model group at 3 days after model making (P<0.05) and lower in the music electroacupuncture group than in the electroacupuncture group at 7 days after model making (P<0.05).Conclusions Music electroacupuncture has a benign regulating effect on intracerebral perifocal ferric ions, inhibits neuronal apoptosis around hematoma in the early stage and reduces cerebral edema in rats with acute cerebral hemorrhage. Its therapeutic effect is superior to that of electroacupuncture.
3.Diagnosis of congenital anomoly of pediatric kidneys by high frequency ultrasound
Hongyan LI ; Xia WANG ; Fengqun DONG ; Yanhui FAN
Chinese Journal of Ultrasonography 2008;17(3):231-233
Objective To discuss the significance of high frequency ultrasound for diagnosis of congenital anomoly of pediatric kidneys. Methods Totally 118 patients with congenital anomoly of pediatric kidneys were examined with high frequency ultrasound,the characteristics of the images were analysed.Results Congenital anomoly kidneys had great diversity of variety in number,size,position,axial direction,abnormal vein and renal pelvis. In the 118 cases,pelvi ureteric stenosis was in 72 cases,renal duplication in 23,renal hypoplasia in 10,kidney deficit in 7,rotatory anomaly in 1,fused kidney in 1,and double renal pelvis in 4. Conclusions High frequency ultrasound is beneficial for diagnosing and differential diagnosing congenital anomoly of pediatric kidneys.
4.Cutaneous lymphoma.
Hong-Min HE ; Wei DONG ; Fan WANG
Chinese Journal of Pathology 2009;38(10):703-704
5.Neuromyelitis optica: a case report.
Si-Hui CHEN ; Fan WANG ; Gui-Rong DONG
Chinese Acupuncture & Moxibustion 2012;32(5):422-422
6.Effects of Stimulative Ways of Scalp Penetration Acupuncture on Acute Stroke
Jianhao LIU ; Fan WANG ; Chunling BAO ; Guirong DONG
Chinese Journal of Rehabilitation Theory and Practice 2016;22(1):92-94
Objective To observe the effect of different stimulative ways of scalp penetration acupuncture on acute stroke. Methods 90 inpatients with acute stroke from July, 2011 to July, 2014 were randomly divided into manual acupuncture group (n=30), electroacupuncture group (n=30) and simple acupuncture group (n=30). All the groups accepted scalp penetration acupuncture from Baihui (GV20) to Taiyang (EX-HN5) and stimulated manually, electrically and simply maintained, respectively. They were assessed with Neurological Deficit Score (NDS), measured with neuron-specific enolase (NSE) before and 14 days after treatment. The incidence of improvement was observed. Re-sults The NDS was the least in the manual acupuncture group (P<0.05), as well as the serumal level of NSE (P<0.05). The incidence of im-provement was the most in the manual acupuncture group (P<0.05). Conclusion The manual stimulation of scalp penetration acupuncture is more effective on the acute stroke.
7.Early effect of tonsillotomy on children′s snoring with tonsil hypertrophy
Xiaoguang WANG ; Mingfu DONG ; Yaqin FAN ; Zhongsheng HAN ; Xiaobo SHUI
International Journal of Laboratory Medicine 2016;37(4):484-486
Objective To explore short-term effect of tonsillotomy on children′s obstructive sleep apnea hypopnea syndrome (OSAHS) with tonsil hypertrophy by Ellman double-frequency radio-frequency machine .Methods Totally 30 cases children′s OS-AHS with tonsil hypertrophy were had tonsillotomy by Ellman double-frequency radio-frequency machine .They were compared with 30 cases children′s OSAHS with tonsil hypertrophy by traditional tonsillectomy .Short-term effect of tonsillotomy were ana-lyzed by wound bleeding ,operation time ,postoperative pain ,difficulty eating ,PSG testing ,immune function ,growth and develop-ment .Results Postoperative symptom in 1 weeks and 6 months ,compared with the traditional tonsillectomy ,30 cases of OSAHS patients were found that there were less bleeding ,shorter operative time ,mild postoperative pain ,no difficulty in feeding ,improving sleep-disordered breathing ,no decline in immune function ,good growth and development .Conclusion Short-term effect of tonsillot-omy on children′s OSAHS with tonsil hypertrophy is good by Ellman double-frequency radio-frequency machine ,it is a minimally invasive ,safe and effective surgical method children OSA HS .
8.Establishment of human lung adenocarcinoma multidrug resistance cell lines induced by paclitaxel and the mRNA expressions of DNA pol?,mdr1,mrp1,GST-?,lrp,and topo Ⅱ genes
Zhiju WANG ; Hongkun FAN ; Min LI ; Guoqiang ZHAO ; Ziming DONG
Journal of Xi'an Jiaotong University(Medical Sciences) 1982;0(04):-
Objective To establish human lung adenocarcinoma multidrug resistance cell lines in vitro,observe their biological characteristics,and investigate the mRNA expressions of DNA pol?,mdr 1,mrp1,GST-?,lrp and topo Ⅱ genes.Methods Paclitaxel-resistant cell lines(A549/TXL20) were established in vitro by exposure to stepwise increased concentrations of the drug in a cell culture medium.Biological morphology and cell cycles were analyzed by morphometry and flow cytometry.The chemoresistance indexes of cells were measured by methyl tetrazolium assay.Evaluation of growth and in vitro drug sensitivity were performed.RT-PCR was employed to analyze the mRNA expressions of the DNA pol?,mdr 1,mrp1,GST-?,lrp,and topo Ⅱ genes.Results ① Compared with parent cells,the resistant sublines had a lower confluent density.They were smaller and mixed with giant cells in different sizes and with different numbers of nucleoli,and the growth property of A549/TXL20 did not change significantly compared with A549 cell lines.② The resistant cells,A549/TXL20,were 19.3 times more resistant to paclitaxel and 67.4 times more resistant to cisplatin than the parent cells,and also demonstrated cross-resistance to mitomycin,vinblastine,and 5-fluouracil(5-FU). ③ Compared with the A549 celllines,an unreasonably higher level of drug resistance and lower drug concentration was detected in A549/TXL20 cells after exposure to the drug in the culture medium.④ The mRNA expression level of DNA pol?,mdr1,GST-?,mrp1 andlrp genes in A549/TXL20 cells was significantly higher than that in A549 cell lines(P
9.Comparison of surgery and conservative treatment for senile dens fractures of Anderson-D Alonzo type Ⅱ or Ⅲ: a Meta-analysis
Huajun LING ; Lei FAN ; Jianwen DONG ; Weiwen LIN ; Qiyou WANG
Chinese Journal of Orthopaedic Trauma 2017;19(3):225-233
Objective To compare the operative and conservative treatments for senile dens fractures of Anderson-D Alonzo type Ⅱ or Ⅲ using Meta-analysis.Methods A literature search was conducted in PubMed,Embase,Web of Science,Cochrane Library,Wanfang Data and CNKI for studies on senile dens fractures of Anderson-D Alonzo type Ⅱ or Ⅲ from the earliest records through June 2016.The relative studies identified were screened by 2 independent authors.The quality of these articles was evaluated using modified Newcastle-Ottawa scale,and the meta-analysis was conducted using Review Manager 5.3.Results A total of 22 articles were brought into this Meta-analysis.The union rate was significantly higher in the operative group than in the conservative group[OR =0.30,95% CI(0.20,0.44),P < 0.001];the mortality in the operative group was significantly lower than in the conservative group[OR =0.61,95% CI (0.39,0.96),P=0.03];the complication rate was similar in both groups[OR=1.09,95% CI(0.76,1.57),P < 0.46].The heterogeneity of all the 3 indexes was low.In the subgroup analysis,the union rate was significantly higher in posterior operations than in anterior operations or conservative treatments (P < 0.05).Conclusion For the elderly patients with dens fracture of type Ⅱ or Ⅲ who can tolerate surgery,operative treatment may be more suitable because it can lead to much better prognosis.
10.The relationship of C-reactive protein, adrenomedullin, brain natriuretic peptide and matrix metalloproteinases with congestive heart failure in the elderly patients
Liyan XIE ; Yanping WANG ; Qian FAN ; Ping LIU ; Hai DONG
Chinese Journal of Geriatrics 2003;0(09):-
Objective To study the relationship of the plasma levels of high sensitive C-reactive protein(hs-CRP),adrenomedullin(ADM),brain natriuretic peptide(BNP)and matrix metalloproteinases (MMPs)with severity of heart falure, the left ventricular ejection fraction and the relationship among them in the elderly patients with congestive heart failure(CHF). Methods The blood samples were obtained from 50 patients with congestive heart failure and 24 healthy controls.The plasma level of hs-CRP was measured by immunoturbidometry.The plasma levels of ADM and BNP were determined by radioimmunoassay.The plasma levels of MMP-2 and MMP-9 were measured with ELISA.Left ventricular ejection fraction(LVEF)was measured by echocardiography. Results The plasma levels of hs-CRP, ADM ,BNP and MMP-2,MMP-9 had significantly negative correlation to LVEF(P