1.Different effects of clozapine and risperidone on levels of blood glucose in patients with schizophrenia
Chinese Journal of Tissue Engineering Research 2001;5(23):144-145
Objective To investigate the different effects of clozapine and risperidone on levels of blood glucose in patients with schizophrenia. Method 200 qualified cases selected from psychiatric department were divided into two groups randomly, of which 100 cases accepted the treatment with clozapine and the other 100 cases with risperidone. Blood glucose tests were used before treatment ,4 weeks after treatment and 8 weeks after treatment Results There was significantly higher blood glucose level in clozapine- treated group than in risperidone- treated group after 4 or 8 weeks treatment. The number of cases who had elevated blood glucose level (>6.1 mmol/L) in clozapine- treated group was significantly more than in risperidone- treated group. Conclusion The glucoregulatory abnormality which leads to glucose elevation in clozapine- treated patients is greater than in risperidone- treated patients. Additional motivation to clinical monitor for antipsychotic treatment- related hyperglycemia is indicated.
2.Study on Preparation and Quality Standard of Shangyangyu Gel
China Pharmacy 2001;0(09):-
OBJECTIVE:To prepare Shangyangyu gel and establish a standard for its quality.METHODS:Shangyangyu gel was prepared using carbamer 940 as matrix.Its content was identified by spectrophotography,with the wavelength set at 516nm,and its other compositions were determined by TLC.RESULTS:The concentration of L-shikonin had good linear correlation with absorbance in the range of 8.048~ 40.24? g? mL-1(r=0.999 8).The average recovery rate was 99.45%(RSD=1.13%).CONCLUSION:This method for preparation of Shangyangyu gel was simple in technique and the standard can be used for the quality control.
3.Application of transplanting different diameter single hair in treatment of part eyebrow defect
Chinese Journal of Medical Aesthetics and Cosmetology 2014;20(6):422-424
Objective To explore the effects of implanting different diameter single hair in treatment of part eyebrow defect.Methods 49 patients with part eyebrow defect,including 37 congenital sparse eyebrows and 12 traumatic eyebrow detect,were performed hair transplantation.Single-hair grafts were harvested from the scalp behind ear or the inferior part of the occiput.Single-hair grafts were implanted according to directions of normal eyebrow.22G or 23G needle was used for stick-andplace insertion.The thick and thin hairs were divided.The thin hairs were implanted into the medial and distal ends and the upper edge,the thick hairs were implanted into the center.Results After 3-10 months follow-up.The reconstructed eyebrows growed slowly,about every 5-7 days needed be trimmed.Two sides eyebrows were symmetry.Because a small amount of transplanted hairs were not alive,twelve patients were performed the second operation for thicker eyebrow.All patients were satisfied with the results.Conclusions In treatment of part eyebrow defect,the results of implanting different diameter single hair are natural and vivid.
4.Impact of self-management of hypertension on self efficacy among community residents
Chinese Journal of Health Management 2013;7(5):304-307
Objective To evaluate the impact of hypertension self-management on self efficacy of community residents.Methods November 2011 to February 2012,twenty-eight medium-sized and better adherence to community was selected from fourteen districts and counties in Beijing.In this community-based randomized controlled trial,323 hypertensive patients were randomly assigned to the treatment group (n =159,receiving hypertension self-management) and the control group (n=164,receiving standard hypertension management).A questionary survey was completed at baseline and 6 weeks.Rank sum test or Chi-square test was used for data analysis.Results The average age of the treatment group or the control group was (61.9 ±9.1) vs (61.8 ±9.0) years old,respectively.No significant difference in mean age,gender and education level was found between the two groups (F =0.164,x2 values were 0.782 and 2.093,respectively ; all P > 0.05).In the treatment group,the scores of fatigue,headache and shortness of breath were declined (when compared with the controlled females,Z =-5.198,-3.873,-2.781 ; P < 0.05).Self-efficacy score of the treatment group was increased after the intervention.Women's symptom management self-efficacy and common disease management self-efficacy were significantly higher (Z=-2.958,-2.582; P < 0.05).In comparison with the control group,before and after self-management,the added scores of communication ability with doctors were increased.But the difference was not statistically significant (P > 0.05).Conclusion Six-week self-management program may improve self efficacy among hypertensive patients.
5.Exploration for teaching reformation of medical chemistry in the nursing major
Chinese Journal of Medical Education Research 2005;0(05):-
A series of reform on the teaching of medical chemistry has been carried out to improve the quality of instruction,which includes the goal of instruction,the content of course and the teaching method.Good results have been achieved.
6.Promoting the Development of the Clinical Medicine By Using Meta-Analysis
You-Dong WEI ; Peng XIE ;
Chinese Journal of Medical Education Research 2003;0(04):-
The article put across Meta-analysis well by giving its definition and analyzing its development. It empha-sized its effect in the clinical medicine and dwelled on dealing with the problems encountered when meta-analysis wasapplied and the solutions to the problems. It also pointed out its significant role in raising the level of clinical medicine,teaching and scientific research.[
7.Comparative study of clinical effect on open and laparoscopic partial nephrectomy treatment for small renal cell carcinoma
Zonglan XIE ; Chuanjiang DONG ; Ziqiang DONG ; Lusheng ZHANG
Journal of Regional Anatomy and Operative Surgery 2015;24(6):634-636
Objective To compare the safety and clinical effect of laparoscopic partial nephrectomy ( LPN) on small renal cell carcino-ma. Methods The records of 65 patients who underwent partial nephrectomy in our hospital from March 2008 to March 2013 were retrospec-tively analyzed. 35 patients were given open partial nephrectomy and the other 30 patients were given LPN. Compared the operative time,blood loss,warm ischemia time,length of stay,positive marginrate,and occurance rate of complications between the two groups. Results There was no statistical difference in the mean size of tumor in the two groups. Compared to the OPN group,there was less blood loss,operative time, hospital stays and warm ischemia time in the LPN group. There was neither positive surgical margin nor renal function damage in the two groups. And during the follow-up period ranged from 6 to 18 months,there was no local recurrence. Conclusion Laparoscopic partial ne-phrectomy has a shorter operation time,less blood loss,shorter length of hospital stay compared with open partial nephrectomy,and it wouldn 't extend the time of warm ischemia,while the clinical effect of the two methods are similar.
8.Effects of Shen-fu on the activity of β-adrenoreceptors in cardiopulmonary resuscitation rats
Weifeng XIE ; Xingyi YANG ; Dong WANG
Chinese Journal of Emergency Medicine 2009;18(1):22-25
Objective To study the effects of Shen-fuinjection onthe activity of β-adrenoreceptor in SD rats with cardiopulmonary resuscitation. Method The exprimerit was done at emergency medical lab of Shanghai Changzheng hospital.Cardiac arrest was induced thngh asphyxiation(succinylcholine)and ice-cold 0.5 mol/L KCI in rats,and resuscitation began at five minutes after cardiac orrest.In this experiment,seventy-two male SD rats were randomizly divided into 9 groups:control group(sham group),routine treatment(O.5 h,2 h,4 h,6 h) groups.and Shen-fu treatment(O.5 h,2 h,4 h,6 h),and each group had 8 rats.Rats of Shen-fh treatment groups were injected with shen-fu(20 mL/kg,20 mL/h)during CPR.3H-prazosln Wag used to determine the activity of β-adrenoreceptor in myocyte. The data of the statistic analysiswere presentedin the for mofmeaj14-standard(4-5)deviation.One-way ANOVA was used for muhig Toup comparison,and t-test for comprarison between two groups.Results[3-adrenoreeeptor reached peak at0.5 h after CPR(247.81±8.91)fmol/mg,reached the lowest level at 4 h(104.17 4-13.87)fmol/mg,and returned to the normal level at 6 h(178.53±10.42)fmol/mg.In the eady period.-adrenorecepter activity in control group[O.5 h:(259.91-4-18.09)finol/mJ was similar to that in Shenfu treatment groups(P>O.05).In the late phase,adrenoreeeptor activity in the Shen-fu treatment groups[2 h:(173.04±18.77)fmol/mg,4 h:(148.72±13.88)finoL/mg]was significantly hi#er than that in the control groups(P<0.05).Conclusiom After CPR, ceplor activity firstly rises and then declines,and Shenfu injection Call significantly increase adrenoreceptor activity of mrs in the later period after CPR.
9.Repairing of cicatricial ectropion with orbicularis oculi myocutaneous flap
Dong LI ; Hongbin XIE ; Jianning LI
Chinese Journal of Medical Aesthetics and Cosmetology 2002;0(01):-
Objective To investigate the state of the art technique of ectropion correction. Methods Orbicularis oculi myocutaneous flap on both upper and lower eyelids was used to correct ectropion. Results From Feb.1994~June 2001, the authors performed correction of ectropion for 24 patients. Among them 19 patients were followed up, and the period of follow-up ranged from 3 weeks to 2 years. All of the followed patients received good results except one who had partial necrosis of the orbicularis oculi myocutaneous flap. Conclusion Orbicularis oculi myocutaneous flap has a rich blood circulation. The ratio of its length and width can be made to be 6∶1, and its contour can be trimmed as one's will. In addition, the flap can be transferred flexibly, and the incision in donor site is hidden in nature wrinkle. With this flap, the ectropion can be repaired as an aesthetic unit in one stage.
10.CT features and differential diagnosis of focal nodular hyperplasia of the liver
Dong CHEN ; Heng PAN ; Changnong XIE
Chinese Journal of Primary Medicine and Pharmacy 2009;16(1):6-7,后插4
Objective To discuss the appearances of focal nodular hyperplasia(FNH) of the liver on the muhiphase helical CT scanning, and to improve its diagnostic accuracy with CT. Methods Helical CT scanning of pre- and post- contrast arterial phase,portal venous phase and delayed phase was performed in 10 cases with surgically and pathologically proved FNH. Results On pre- contrast scans,9 of 11 FNH lesions were hypodense(either homo-geneous or non-homogeneous), the other two lesions were isodense. On the arterial phase scans, all lesions were markedly and homogeneously enhanced,except for the central scar area. Tortuous and dilated arteries were seen at the center or peripheral area in 3 out of 11 lesions. On the portal phase and delayed phase scans ,4 of 11 lesions turned to isedanse of slightly hypodense,7 lesions remained slightly hyperdense. Central scar was found in 8 FNH lesions ,2 of them showed no enhancement while the other six demonstrated late enhancement. Conclusion Mulfiphase helical CT scanning can fully reflect the blood supplying and pathologic features of FNH, and it is of great value in diagnosing and differentiating FNH.