Objective To investigate the different effects of clozapine and risperidone on levels of blood glucose in patients with schizophrenia. Method 200 qualified cases selected from psychiatric department were divided into two groups randomly, of which 100 cases accepted the treatment with clozapine and the other 100 cases with risperidone. Blood glucose tests were used before treatment ,4 weeks after treatment and 8 weeks after treatment Results There was significantly higher blood glucose level in clozapine－ treated group than in risperidone－ treated group after 4 or 8 weeks treatment. The number of cases who had elevated blood glucose level (>6.1 mmol/L) in clozapine－ treated group was significantly more than in risperidone－ treated group. Conclusion The glucoregulatory abnormality which leads to glucose elevation in clozapine－ treated patients is greater than in risperidone－ treated patients. Additional motivation to clinical monitor for antipsychotic treatment－ related hyperglycemia is indicated.

OBJECTIVE:To prepare Shangyangyu gel and establish a standard for its quality.METHODS:Shangyangyu gel was prepared using carbamer 940 as matrix.Its content was identified by spectrophotography,with the wavelength set at 516nm,and its other compositions were determined by TLC.RESULTS:The concentration of L-shikonin had good linear correlation with absorbance in the range of 8.048～ 40.24? g? mL-1(r=0.999 8).The average recovery rate was 99.45%(RSD=1.13%).CONCLUSION:This method for preparation of Shangyangyu gel was simple in technique and the standard can be used for the quality control.

Objective To explore the effects of implanting different diameter single hair in treatment of part eyebrow defect.Methods 49 patients with part eyebrow defect,including 37 congenital sparse eyebrows and 12 traumatic eyebrow detect,were performed hair transplantation.Single-hair grafts were harvested from the scalp behind ear or the inferior part of the occiput.Single-hair grafts were implanted according to directions of normal eyebrow.22G or 23G needle was used for stick-andplace insertion.The thick and thin hairs were divided.The thin hairs were implanted into the medial and distal ends and the upper edge,the thick hairs were implanted into the center.Results After 3-10 months follow-up.The reconstructed eyebrows growed slowly,about every 5-7 days needed be trimmed.Two sides eyebrows were symmetry.Because a small amount of transplanted hairs were not alive,twelve patients were performed the second operation for thicker eyebrow.All patients were satisfied with the results.Conclusions In treatment of part eyebrow defect,the results of implanting different diameter single hair are natural and vivid.

Objective To evaluate the impact of hypertension self-management on self efficacy of community residents.Methods November 2011 to February 2012,twenty-eight medium-sized and better adherence to community was selected from fourteen districts and counties in Beijing.In this community-based randomized controlled trial,323 hypertensive patients were randomly assigned to the treatment group (n =159,receiving hypertension self-management) and the control group (n=164,receiving standard hypertension management).A questionary survey was completed at baseline and 6 weeks.Rank sum test or Chi-square test was used for data analysis.Results The average age of the treatment group or the control group was (61.9 ±9.1) vs (61.8 ±9.0) years old,respectively.No significant difference in mean age,gender and education level was found between the two groups (F =0.164,x2 values were 0.782 and 2.093,respectively ; all P ＞ 0.05).In the treatment group,the scores of fatigue,headache and shortness of breath were declined (when compared with the controlled females,Z =-5.198,-3.873,-2.781 ; P ＜ 0.05).Self-efficacy score of the treatment group was increased after the intervention.Women's symptom management self-efficacy and common disease management self-efficacy were significantly higher (Z=-2.958,-2.582; P ＜ 0.05).In comparison with the control group,before and after self-management,the added scores of communication ability with doctors were increased.But the difference was not statistically significant (P ＞ 0.05).Conclusion Six-week self-management program may improve self efficacy among hypertensive patients.

A series of reform on the teaching of medical chemistry has been carried out to improve the quality of instruction,which includes the goal of instruction,the content of course and the teaching method.Good results have been achieved.

The article put across Meta-analysis well by giving its definition and analyzing its development. It empha-sized its effect in the clinical medicine and dwelled on dealing with the problems encountered when meta-analysis wasapplied and the solutions to the problems. It also pointed out its significant role in raising the level of clinical medicine,teaching and scientific research.[

Objective To compare the safety and clinical effect of laparoscopic partial nephrectomy ( LPN) on small renal cell carcino-ma. Methods The records of 65 patients who underwent partial nephrectomy in our hospital from March 2008 to March 2013 were retrospec-tively analyzed. 35 patients were given open partial nephrectomy and the other 30 patients were given LPN. Compared the operative time,blood loss,warm ischemia time,length of stay,positive marginrate,and occurance rate of complications between the two groups. Results There was no statistical difference in the mean size of tumor in the two groups. Compared to the OPN group,there was less blood loss,operative time, hospital stays and warm ischemia time in the LPN group. There was neither positive surgical margin nor renal function damage in the two groups. And during the follow-up period ranged from 6 to 18 months,there was no local recurrence. Conclusion Laparoscopic partial ne-phrectomy has a shorter operation time,less blood loss,shorter length of hospital stay compared with open partial nephrectomy,and it wouldn 't extend the time of warm ischemia,while the clinical effect of the two methods are similar.

[Objective] The purpose is to determine the effect of Chaihu Plus Longgumuli Decoction(CD)on behaviors and plasma adrenocorticotropic hormone(ACTH)level changed by psychological stress in rats.[Methods] Male Sprague-Dawley rats were randomly allocated to four groups as follows:normal(C),psychological stress model(P),CD(12.5g/kg,ig)+P(DP),and CD(25g/kg,ig)+P(HP).One week later,rats were subjected to psychological stress.The behaviors of rats were tested in open field conditions,and the plasma ACTH level was detected by radioimmunoassay.[Results] The crossing scores,the rearing cores and plasma ACTH level increased more significantly in the psychological stress model rats than that in normal group;Rats in both DP and HP groups showed lower crossing and rearing cores and blunted elevation of plasma ACTH after psychological stress compared with rats in psychological stress model.[Conclusion] The hypothalamo-pituitary-adrenocortical(HPA)axis function and anxiety-like behavior could be regulated by CD during psychological stress in rats.

Objective To study the expressions of cyclooxygenase-2(COX-2) and epidermal growth factor receptor(EGFR) in tumor tissues and explore the effect of COX-2 and EGFR in NSCLC development.Methods The expression of COX-2 and EGFR was detected by immunohistochemical technique in 56 cases of non-small cell lung cancer(NSCLC) and in 20 cases of normal lung tissues.Results The expression of COX-2 and EGFR in NSCLC was significantly higher than that in normal lung tissues(P

Objective To analyze CT features of extra-gastrointestinal stromal tumom(EGIST).Methods The CT data of 9 pa-tients with EGIST proved by operation and pathology were analysed retrospectively.Results Of 9 cases with EGIST,7 cases were malignant and 2 cases were benign.2 cases were origina-ted from liver.2 cases from mesocolon,2 cases from Small mesentericin,2 case showed widely diffuse nodules scattered in peritoneum,omentum,small intestine,mesangial and colon serosa.In those nodules, some nodules from pelvic cavity wereinosculated into larger mass.1 case came from right kidney week gap.The biggestdiameter of tumomrs of each case was ranged from 5.0 cm to 14.0 cm (mean 9.6 cm).5 cases showed lobulated shape,4 cases showed round or oval.All cases showed non-homogeneous density in plain CT,with cystic change and necrotic foci in 7cases,calcification in 2 cases.In arterial phase,all cases appeared significantly abnormal thickening or multiply tumor blood vessels in edge and center of those tumors.Conclusion EGIST has unique imaging performance.