Cerebral Palsy ; physiopathology ; rehabilitation ; Child ; Disability Evaluation ; Humans ; Motor Skills ; Movement ; Muscle Spasticity ; physiopathology ; rehabilitation ; Neuropsychological Tests

Objective We aimed to assess the influence of space teaching on junior-college nursing students' autonomous learning ability.Methods Using random number table,two classes of junior-college nursing students of Grade 2012 were selected and divided into the experimental group (46 students) and the control group (47 students) according to their classes.Students in the control group received routine multimedia teaching.Students in the experimental group received space teaching based on the platform of World University City.The effect of space teaching on developing nursing students' autonomous learning ability was assessed with the help of their test results and the nursing students' autonomous learning ability evaluation form.Results After carrying out space teaching,the average grade,theoretical performance,total points,the total score of autonomous learning ability and the score of each dimension in the experimental group and the differences were remarkably higher than those of the control group (t value was 2.80,2.45,2.29 and 11.58).Conclusions Space teaching can assist in arousing nursing students' learning motivation and improving nursing students' independent learning ability.It can be used for reference and promoted.

Hematopoietic stem cell transplantation (HSCT) has been widely performed for patients with various genetic and acquired malignant and non-malignant diseases.Central nervous system (CNS) complications are considered an important cause of morbidity and mortality after HSCT.This review discuss the main causes of CNS after HSCT such as infection,drug toxicity,graft-versus-host disease,metabolic encephalopathy,neurologic relapses etc,so as to benefit the early recognition of CNS complications and to improve the prognosis of patients after HSCT.

Homocysteine ( Hcy) is an independent risk factor for a variety of diseases and closely related to cardiac-cerebralvascu-lar diseases, neurological diseases, diabetes and diabetic com-plications. High homocysteine levels can significantly increase the recurrence risks of cardiac-cerebralvascular events and stroke in patients with stroke, leading to high all-cause mortality. The risk of Alzheimer’s disease is increased by 1. 8 fold when the concentration of Hcy is over 14 μmol·L-1 . For each 5 μmol· L-1 increase in plasma Hcy in diabetes patients, the mortality rate increases by 5 fold in the next five years. High Hcy triggers the pathogenesis of diseases via multiple mechanisms including oxidative stress, lesions of vascular endothelial cells, prolifera-tion of vascular smooth muscle cells, dysfunction of coagulation and lipid metabolism and genomic hypomethylation etc.

[Objective] To research professor Yu’s experience in treating chronic cough of children.[Method] The paper expounds Professor Yu ’s experience in treating chronic cough of children by analyzing the etiology,pathology ,summarizing the clinical thoughts and citing some typical cases. [Result] The therapies of expel ing wind and activating blood circulation,strengthening body resistance and eliminating evil ,using both cold and warm are respectively effective in treating whoop,internal injury cough and pharyngitis. [Conclusion] When treating chronic cough of children, Professor Yu always gives consideration to the local environment,climate and the children ’s individual physique,takes care of both tip and root and makes use of simultaneous application of reducing and nourishing therapies,that has instructive significance.

Objective:To observe the clinical treatment effects of Tangkang Xifang in the patients with type 0 diabetes foot ( DF) . Methods:Totally 73 patients with type 0 DF were randomly divided into the treatment group (n=37) and the control group (n=36). All the patients discontinued other medications for 7d before the treatment. Base on the blood glucose control with the traditional treat-ment by metformin hydrochloride (1. 5 g·d-1), the treatment group was additionally given warm water foot bath with Tangkang Xi-fang, while the control group was additionally given warm water foot bath, 30 min per time and twice a day for 60 days. The changes in the clinical symptoms, ankle brachial index ( ABI) , motor nerve conduction velocity ( MCV) and some other indices were measured before and after the treatment. Results:In comparison with the control group (58. 3%), the treatment group had higher total effective rate (86. 5%), and the usage of Tangkang Xifang also significantly improved the physiopathologic syndromes of peripheral artery dis-ease and neuropathy (P<0. 01). The ABI and MCV in the treatment group were significantly better than those in the control group (P<0. 05 or P<0. 01). Conclusion:Tangkang Xifang can effectively improve the clinical symptoms of type 0 DF, which is suitable for the clinical application.

In both clinical and animal experiments,it has been confirmed that the inflammation in heart is involved in the development of heart injury after the ischemia/reperfusion.However,the pro-inflammatory mechanism is extremely complicated.Recently,a growing number of reports indicates that many factors play their roles in the inflammation,such as cytokinemia,inflammatory cells,metabolic product of arachidonic acid and COX et al.They are released/presented in the region of myocardial ischemia/reperfusion and include both ischemic and secondary heart injury.

Objective To study the correlation between ?-fibrinogen gene variation (-455G/A) and plasma fibrinogen level and cerebral infarction.Methods 86 hypertension patients with cerebral infarction(infarction group),85 hypertension patients without cerebral infarction(hypertension group) and 90 healthy people(control group) were enrolled in this trial. The polymorphism of ?-fibrinogen gene-455G/A located at the start of transcription from all subjects was analyzed by polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP) technique. Plasma fibrinogen level was measured with prothrombin time (PT) assay.Results The fibrinogen level in infarction group(4.82?0.26 g/L) was significantly higher than that in control group(4.37?0.19 g/L)( P 0.05).The A-455 allele frequency in infarction group was significantly higher than those in control group and hypertension group (all P 0.05). Conclusion Plasma fibrinogen level is affected by the ?-fibrinogen gene -455G/A polymorphism. The fibrinogen A-455 allele may be an independent risk factor of cerebral infarction.

The thoracic ossification of the ligamentum flavum(OLF)is usually located in the lower thoracic spine.Thoracic OLF has been widely recognized as a main cause of thoracic myelopathy.The pathogenesis of OLF is poorly understood.Because the thoracic OLF has many clinical manifestations and it is commonly combined with other spinal disorders,it is easy to be misdiagnosed or to be a delayed diagnosis.The surgical treatment of thoracic OLF has high risk and Serious complications.In this paper the pathogenesis,diagnosis and treatment of thoracic ossification of ligamentum flavum in recent years are reviewed.