1.Problems and solutions for information service to foreign students in academic library
Chinese Journal of Medical Education Research 2005;0(06):-
This paper analyses the problems of information service to foreign students in the library of Dali University and put forwards the proper solutions.
2.Relationship between human papillomavirns and cervical carcinoma
Bin YU ; Peizhen XU ; Qiuwei WANG ; Yishan DONG ; Bin ZHANG
Chinese Journal of General Practitioners 2009;8(4):238-240
Objective To explore the relationship between high-risk human papillomavirus (HPV) DNA and biological behavior of cervical carcinoma. Methods Sixty-six patients of cervical carcinoma with cytological examinations and 103 patients of cervical carcinoma followed-up after surgical operation were selected for high-risk HPV DNA test with second-generation hybrid capture technique (HC2 Ⅱ). Results ①HPV DNA was positive in 62 and negative in four of 66 patients of cervical carcinoma with an overall prevalence of 94%. ②There was no significant difference in positive HPV DNA of patients with cervical carcinoma between their varied clinical stages and pathologic grades. But, HPV positivity and HPV DNA load in patients with myometrial invasion were higher than those in patients without invasion (P < 0. 05).③ HPV DNA conversed to negative in 99 of 103 patients (96%) with cervical carcinoma after surgical operation from positivity before operation. Conclusions High-risk HPV infection may correlate with angiogenesis, invasion and metastasis of cervical carcinoma and HC2 Ⅱ can be used as an effective method to detect HPV DNA.
3.Surgical results of complicated ocular trauma with cyclodialysis
Bin YU ; Xiaoguang DONG ; Jinyan WANG
Chinese Journal of Ocular Fundus Diseases 2010;26(6):517-520
ObjectiveTo explore the surgical techniques, efficacy and the management of complicated ocular trauma with anterior-posterior segment complications such as cyclodialysis. Methods Fifty-five patients (55 eyes) with complicated ocular trauma were enrolled in this study. Among them, there were 35 cases with eyeball contusion and 20 cases of eyeball rupture. Preoperative visual acuity was from no light perception to 0. 15, intraocular pressure (IOP) ranged from one to 10 mm Hg (1 mm Hg=0. 133 kPa).Cyclodialysis, vitreous hemorrhage or retinal detachment were revealed by B-ultrasound and ultrasound biomicroscopy (UBM). Cyclodialysis clefts ranged from one to 12 clock-hours. All patients underwent 3-port pars plana vitrectomy with gas/silicone oil tamponade and ciliary body reattachment by cryotherapy (cyclodialysis clefts ≤ three clock-hours) or suture fixation ( cyclodialysis clefts > three clock-hours).Healing after surgical trauma, visual acuity, intraocular pressure, intraocular hemorrhage, ciliary body and retinal reattachment were followed up. Results In one month after surgery, UBM showed 54 patients out of 55 patients had good ciliary body reattachment. Gonioscopy revealed cyclodialysis still existed in one patient, and this was cured by a second surgical suture fixation. In three months after surgery, ocular trauma healed in all 55 patients, the visual acuity ranged from no light perception to 0. 15, with a best corrected visual acuity of 0.8. The ciliary body and retina had good reattachment. IOP of 52 patients was normal; IOP of three patients was still lower than 10 mm Hg. Three patients had secondary glaucoma which was treated by glaucoma surgery. Conclusions Complicated ocular trauma with cyclodialysis can be treated with vitrectomy and cryotherapy or transscleral sutures. The procedure is safe and effective.
4.Comparison of Clinical Effects Between Totally Video-assisted Thoracoscopic Surgery and Conventional Median Sternotomy for Mitral Valve Replacement
Bin WANG ; Yunge CHENG ; Nianguo DONG
Chinese Journal of Minimally Invasive Surgery 2015;(8):681-683
Objective To compare clinical effects between totally video-assisted thoracoscopic surgery and conventional median sternotomy for mitral valve replacement . Methods From March 2012 to October 2013, patients with simple mitral valve disease underwent mitral valve replacement through either right chest port -access totally video-assisted thoracoscopy ( thoracoscopy group, n=110) or conventional median sternotomy (conventional group, n=128).The time of operation, cross-clamp ascending aorta, cardiopulmonary bypass , postoperative mechanical ventilation , intensive care unit stay , postoperative hospital stay , and volume of postoperative chest drainage were compared between the two groups .All the patients were followed after 6 months postoperatively for evaluating the condition of valve regurgitation under echocardiography . Results Between the thoracoscopy group and the conventional group, no significant differences were found in time of operation [(256.2 ±28.5) min vs.(251.2 ±30.0) min, t=1.312, P=0.191], cross-clamp time of the ascending aorta [(40.0 ±2.7) min vs.(39.4 ±2.7) min, t=1.709, P=0.089], and cardiopulmonary bypass time [(74.2 ±4.1) min vs.(73.7 ±4.9) min, t =0.846, P =0.399].As compared to the conventional group, the thoracoscopy group had significantly shorter time of postoperative mechanical ventilation [(716.4 ±79.1) min vs.(811.9 ±58.8) min, t=-10.657, P=0.000], shorter length of intensive care unit stay [(26.2 ±3.6) h vs.(29.3 ±4.7) h, t=-5.640, P=0.000], shorter length of postoperative hospital stay [(9.6 ±1.2) d vs.(10.9 ±2.5) d, t=-4.982, P=0.000], and less volume of postoperative chest drainage [(328.1 ±83.2) ml vs.(561.3 ±143.9) ml, t=-14.978, P=0.000], respectively .No death happened in the two groups . No mitral valve regurgitation was seen during follow-ups at 6 months postoperatively . Conclusion For patients undergoing mitral valve replacement , totally video-assisted thoracoscopic surgery is superior to conventional median sternotomy with respect to surgical trauma .
5.Coronary angiography by transradial approach with modified 5 F universial catheter
Peng DONG ; Bin WANG ; Weihua JIN
Chinese Journal of Interventional Cardiology 1996;0(04):-
Objective To study the feasibility and safety of the diagnostic coronary angiography by transradial approach with modified 5 F universial catheter.Methods Retrospective analysis was performed in 268 randomly chosen patients undergoing diagnostic coronary angiography by transradial approach,either with 5 F universial catheter(universial group,n=133) or 5 F modified universial catheter(modified group,n=135).The success rate and the duration of operation and fluoroscopy,the rate of error entry into branch vessel between the 2 groups were compared.Results The success rate for angiography was 87.2%(116/133) in the universal group and 97.0%(131/135) in the improved group(P
6.Enhanced radiosensitivity of H22 ascitic tumor to 12C6+ ions radiation in ultra-filtration extract mixture from Astragalus mongholicus-treated mice.
Bin-bin WANG ; Xiao-hu WANG ; Kai LIU ; Shao-bo SUN ; Peng SONG ; Ying-dong LI
Acta Pharmaceutica Sinica 2015;50(12):1596-1602
This study was designed to investigate the impact of ultra-filtration extract mixture from Astragals mongholicus (UEMAM) o radiosensitivity of H22 ascitic tumor in mice to 12C6+ ions radiation. The H22 ascitic tumor model was established in mice by intraperitoneal injection of 0.2 mL H22 ascitic cells. The animals were subsequently divided into 4 groups randomly, treated with normal saline, UEMAM, heavy ion beam radiotherapy and UEMAM plus heavy ion beam radiotherapy, respectively. The body weights, abdomen circumference of the mice were measured and the mouse behavior was monitored every day; survival time was recorded to evaluate life extension effect; flow cytometry technique was used to detect H22 cell apoptosis and cell cycle; protein levels of p53, Bax, Bcl-2 and cleaved Caspase-3 were analyzed by Western blot; the single cell gel electrophoresis was used to detect the level of deoxyribonucleic acid damage (DNA damage). The results suggest that UEMAM significantly increased survival time, and decreased body weights and abdomen circumference over the saline control group. The treatment increased cell apoptosis, cycle arrest and DNA damage compared to the saline control group. UEMAM significantly enhanced the therapeutic effect of heavy ion beam radiation in survival time, and decreased body weights and abdomen circumference in the tumor-baring mice. The combination increased cell apoptosis, cycle arrest and DNA damage compared to the radiotherapy group. The results of Western blot suggest that the treatment significantly enhanced p53-induced apoptotic signals. The experiment discovered that UEMAM could improve radiosensitivity of H22 ascitic tumor through activation of p53-mediated apoptotic signal pathway.
Animals
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Apoptosis
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Astragalus Plant
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chemistry
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Cell Cycle
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Cell Line, Tumor
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DNA Damage
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Ions
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Mice
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Neoplasms, Experimental
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drug therapy
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radiotherapy
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Plant Extracts
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pharmacology
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Radiation Tolerance
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Signal Transduction
7.An improved wavelet threshold algorithm for ECG denoising.
Xiuling LIU ; Lei QIAO ; Jianli YANG ; Bin DONG ; Hongrui WANG
Journal of Biomedical Engineering 2014;31(3):511-515
Due to the characteristics and environmental factors, electrocardiogram (ECG) signals are usually interfered by noises in the course of signal acquisition, so it is crucial for ECG intelligent analysis to eliminate noises in ECG signals. On the basis of wavelet transform, threshold parameters were improved and a more appropriate threshold expression was proposed. The discrete wavelet coefficients were processed using the improved threshold parameters, the accurate wavelet coefficients without noises were gained through inverse discrete wavelet transform, and then more original signal coefficients could be preserved. MIT-BIH arrythmia database was used to validate the method. Simulation results showed that the improved method could achieve better denoising effect than the traditional ones.
Algorithms
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Arrhythmias, Cardiac
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Databases, Factual
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Electrocardiography
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Humans
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Signal Processing, Computer-Assisted
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Wavelet Analysis
8.Analysis of the causes of postoperative hemorrhage of tracheotomy in patients with liver transplantation.
Bao-dong WANG ; Ai-hua SUN ; Bin-hua DENG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2006;41(12):953-954
Adult
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Aged
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Female
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Humans
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Liver Transplantation
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adverse effects
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Male
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Middle Aged
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Postoperative Hemorrhage
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etiology
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Tracheotomy
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adverse effects
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Young Adult