1.Diagnostic value of lysine-aspirin bronchoprovocation test for aspirin-sensitive asthma.
Hae Sim PARK ; Yoon Jeong KIM ; Hee yeon KIM ; Dong Ho NAHM ; Yoon Bo YOON
Korean Journal of Allergy 1997;17(2):171-179
Aspirin(ASA) and NSAIDs can induce bronchoconstriction in 10~20% of adult asthmatics patients. Inhalation of lysine-ASA(L-ASA) has been described as an alternative method for diagnosis of ASA-sensitive asthma. To further understand the characterlstics of ASA-sensitive asthmas. we studied 38 asthmatic patients with ASA -sensitivity (36 intrinsic and 2 extrinsic asthma) proven by L-ASA bronchoprovocation test (BPT). Most were female (male to female ratio was 27:73). Twenty (53%) of them had no previous history of adverse reactions when exposed to ASA. Twenty nine (79%) had rhino-sinusitis symptoms. Early asthmatic response was observed in 16 (42%) patients, late only response in 16(42%), and dual response in 6(16%) patients. The threshold of L-ASA to provoke a positive response ranged from 11.2 to 180 mg/ml and most (68.3%) had a positive response after the inhalation of 180 mg/ml. Concurrent sensitivity to sulfite was noted in 14 (36%) patients, followed by sensitivity to tartrazine in one (3%) patient. None showed a positive response to sodium benzoate. After the avoidance from ASA/ NSAIDs with administration of anti-asthmatic medications, symptom and medication scores reduced in 26(87%) patients among 30 followed patients. They were classified into the improved group: four (13%) patients belonged to the not-improved group. There were no significant differences in clinical characteristics between the improved and not- improved group (p>0.05). In conclusion, L-ASA BPT could be considered as a useful method to diagnose ASA -sensitive asthma and be used to screen the causative agent for asthmatic patients with intrinsic type, especially in female patients with rhino-sinusitis and/or nasal polyp, even though they do not have arty history of adverse reactions. Cessation of exposure and proper treatment may allow to reduce symptom and medication scores.
Adult
;
Anti-Inflammatory Agents, Non-Steroidal
;
Asthma*
;
Bronchoconstriction
;
Diagnosis
;
Female
;
Humans
;
Inhalation
;
Nasal Polyps
;
Sodium Benzoate
;
Tartrazine
2.Magnetic Resonance Imaging Findings of Intraspinal Neurenteric Cyst: Case Report.
Dong Ik KIM ; Choon Sik YOON ; Pyeong Ho YOON ; Tae Sub CHUNG ; Sang Wook YOON
Journal of the Korean Radiological Society 1994;31(4):621-625
Intraspinal neurenteric cysts are rare congenital lesions that results from abnormal separation of germ layers in the third week of embryonic development, which may cause spinal compression. Although, the diagnosis of neurenteric cyst was very difficult prior to operation, MRI has proven to be a useful imaging modality in detection, localization and characterization of intraspinal neurenteric cysts. We recently experienced intraspinal neurenteric cyst in two patients who presented with progerssive quadriparesis. Myelography, CT myelography and MRI were taken and complete excision was performed. The MRI findings are presented and the literature is reviewed.
Diagnosis
;
Embryonic Development
;
Female
;
Germ Layers
;
Humans
;
Magnetic Resonance Imaging*
;
Myelography
;
Neural Tube Defects*
;
Pregnancy
;
Quadriplegia
4.A Urodynamic Database Management using MS Access Computer Program.
Kap Byung KIM ; Dong Woo RO ; Duk Yoon KIM
Journal of the Korean Continence Society 1999;3(1):35-40
No abstract available.
Urodynamics*
5.An Immunohistochemical Study of Vascular Endothelial Growth Factor as a Predictor of Progression in Bladder Cancer.
Jong Bo CHOI ; Dong Hee YOON ; Dong Sun KIM ; Duck Ki YOON ; Jae Heung CHO
Korean Journal of Urology 2000;41(7):807-811
No abstract available.
Urinary Bladder Neoplasms*
;
Urinary Bladder*
;
Vascular Endothelial Growth Factor A*
6.Intracerebral Hemorrhage in Eclampsia : Two Cases Report.
Dong Yoon NAM ; Soo Jung YOO ; Jong In KIM
Korean Journal of Obstetrics and Gynecology 2000;43(9):1679-1683
No abstract available.
Cerebral Hemorrhage*
;
Eclampsia*
;
Female
;
Pregnancy
7.Two-year Follow-up after Visual Laser Ablation of Prostate (V-LAP) for BPH.
Jong Bo CHOI ; Dong Sun KIM ; Duck Ki YOON
Korean Journal of Urology 2000;41(12):1546-1550
No abstract available.
Follow-Up Studies*
;
Laser Therapy*
;
Prostate*
8.Vitiliginous Hypopigmented Patches Developed during Photochemotherapy ( PUVA ) in a patient with Psoriasis.
Yoon Kee PARK ; Dong Hoon SONG ; Hyung Joo KIM
Korean Journal of Dermatology 1987;25(5):629-632
We observed a 51-year-old male, who developed depigmented patches on the lower abdomen after photochemotherapy(PUVA) of psoriasis without evidence of phototoxic reaction. The depigmented patches did not orginate from the sites of previous psoriatic lesions. Fontana-Masson stain of the biopsy specimen revealed nearly absent melanin pigments in the epidrmis of the hypopigmented patch, while lots of pigments were obsereved on the surrounding hyperpigmented area. Electron micrograph showed no melanocytes in the hypopigmented patch. Thus we report this case as having vitiliginous patches induced by photochemotherapy of psoriasis.
Abdomen
;
Biopsy
;
Humans
;
Male
;
Melanins
;
Melanocytes
;
Middle Aged
;
Photochemotherapy*
;
Psoriasis*
;
Vitiligo
9.A Case of Marginal Keratoderma of the Palms.
Yoon Kee PARK ; Seung Eon BAEK ; Dong Kun KIM
Korean Journal of Dermatology 1985;23(1):72-76
We herein report a 28-year-old woman with typical marginal keratoderma of the palms of 4 years duration. She denied any chronic pressure or trauma. Histological findings disclosed marked hyperkeratosis, parakeratosis, acanthosis, elongation of rete ridges, edema and capillary dilatations of papillary dermis, and infiltration of chronic inflammatory cells. There was no changes in collagenous and elastic fibers. Treatment with oral 13-cis retinoid and topical application of 0.02% flumethasone ointment containing 3%, salicylate resulted in only transit effect.
Adult
;
Capillaries
;
Collagen
;
Dermis
;
Dilatation
;
Edema
;
Elastic Tissue
;
Female
;
Flumethasone
;
Humans
;
Parakeratosis
10.The Relationship of Ki-67, Proliferating Cell Nuclear Antigen, AgNORs and p53 Protein Expression in Astrocytoma.
Dong Ja KIM ; Jae Weon LIM ; Yoon Kyung SOHN
Korean Journal of Pathology 1999;33(1):25-31
The grading of astrocytoma has traditionally relied on histological assessment, but there are some differences in their parameters, application, and reproducibility. Recently, numerous studies have attempted to correlate biological aggresiveness with tumor proliferation index using new immunohistochemical methods. The purpose of this study is to correlate the histopathological grades of astrocytoma with the expression of Ki-67, PCNA, p53 protein and AgNORs. The paraffin sections of 41 consecutive cases of astrocytomas were examined. Histologically the tumors were graded as three groups under the St. Anne-Mayo system and showed 14 cases in grade II, 15 cases in grade III and 12 cases in grade IV (glioblastoma multiforme). As a result, the Ki-67 labelling index and p53 protein expression tended to increase with increasing grade of malignancy. But the univariate analysis showed that there was no significant difference between the tumor grades (p>0.05). The PCNA labelling index and number of AgNORs revealed striking differences between the grade II and grade III astrocytomas (p<0.05). We concluded that the PCNA labelling index and AgNORs counting are useful markers for differentiation between grade II and III astrocytomas.
Astrocytoma*
;
Paraffin
;
Proliferating Cell Nuclear Antigen*
;
Strikes, Employee