Objective To analyze the quality of life(QOL)of patients with acute stroke,and to explore the effects of early specialized rehabilitation on their QOL.Methods Seventy patients with acute stroke were randomly divided into a rehabilitation group(n =35)and a control group(n =35).The rehabilitation group received specialized rehabilitation treatment while the control group received self-rehabilitation.QOL we evaluated with the short form-36(SF-36)instrument before and after.Results Before treatment,QOL scores in the both groups were much lower than the norms for healthy people.The differences on each dimension of the SF-36 were not statistically significant between the two groups.The SF-36 scores of both groups improved during the experiment,but after 1 month and 6 months the improvement on each SF-36 dimension was significantly better in the rehabilitation group than in the control group.Conclusions The QOL of patients with acute stroke is significantly impaired,but specialized rehabilitation treatment is effective in improving it.

Bacteria ; classification ; growth & development ; Candida ; growth & development ; Humans ; Infant ; Infant, Newborn ; Mouth ; microbiology

Objective To analyze clinical and pathologic features of a rare vascular amyloid deposits of amyloid nephropathy ( VADAN) in 6 patients, so as to improve its diagnosis and treatment. Methods All patients received immunopathology, microscopy and electron microscopy examination, and amyloid types were analyzed. Results There were 3 males and 3 females with ages ranging from 52 to 73 years. Two patients suffered from multiple myeloma. Majority patients had slight albuminuria and hematuria. One patient combined with minimal change glomerular disease presented nephrotic syndrome. One patient combined with IgA nephropathy had albuminuria and hematuria. And one patient had myeloma cast nephropathy with acute renal failure. Kidney biopsy proved amyloid deposits along interlobular arterial wall only in all 6 patients. Two cases secondary from multiple myeloma were κ amyloid, and the rests were λ amyloid. Conclusions VADAN is a rare type of amyloid nephropathy. Its clinical manifestation is different from common amyloid nephropathy. Kidney biopsy will benefit its differential diagnosis.

Abdominal aortic aneurysms(AAAs) is the most common aneurysm,and usually characterized by less symptom.While ruptured AAAs leads to high mortality.Abdominal ultrasonography can effectively detect AAA,decrease the AAAs-related mortality.However,screening AAAs causes some adverse outcomes,including psychological distress and immediate harms in treatment.Meanwhile,the prevalence of AAAs in sex and age is significantly different.Therefore,a reasonable and effective screening strategy is very important.This article search random control trials,systematic reviews,meta-analysis and guidelines in screening AAAs to obtain a reasonable screening strategy.

To investigate whether the MCs of colon mucosa is elevated in IBS, and to eluciate their possible roles in IBS, biopsies of the terminal ileum, ICJ, ascending colon, and sigmoid colon were stained specifically with histochemistry for the MCs in 15 controls and 28 patients with IBS. The results were investigated qualitatively and quantitatively by color image analyzer. The structure relation between MC and nerves or cells was studied by ultramicroscopy. The results showed the number of MCs in the terminal ileum, ICJ, and ascending colon, was significantly elevated in IBS( P

Objective To observe the rectal visceral perception to balloon distention and the changes o f mast cells (MCs), substance P(SP) and the vasoactive intestinal ploypeptide(VI P) in irritable bowel syndrome(IBS), and to investigate their possible roles in IBS. Methods The biopsies of the terminal ileum, the ilecocecal junctio n(ICJ), the ascending colon and the sigmoid colon were stained with histochemist ry fo r the MCs and with immunohistochemistry for SP and VIP in 19 controls, 22 diarrh ea-predominant IBS (D-IBS) patients and 20 constipation-predominant IBS (C-I BS) patients. The results were investigated qualitatively and quantitatively by color image analyzer. The structural relation between MC and nerves or cells was studied through an ultramicroscopy. Rectal visceral perception thresholds to b alloon distention, rectal compliance and anorectal manometry were examined by me ans of electric barastat and perfusion catheter manometer. Results The number of the MCs in the terminal ileum, ICJ and ascen ding colon was significantly elevated in IBS patients ( P 0.05); rectal complianc e decreased significantly ( P

Objective The aim of this study was to assess the expression of protein products of Hugl-1 (human lethal-giant-lavae 1)in non-small cell lung cancer(NSCLC), to estimate their possible expression and to correlate the results of immunohistochemical analysis with various clinicopathologic parameters. Methods The expression of Hugl-1 gene was detected by immunohistochemical S-P method in 50 cases of NSCLC tissues ,50 para-cancer tissues and 10 cases of lung benign lesion tissues as control. Results (1)The expression level of Hugl-1 gene was found to be significantly lower in NSCLC tissues than in para-cancer tissues and lung benign lesion tissues(P

Liver transplantation (LT) is effective for suitable patients with HCC and may be the only curative treatment for those with unresectable HCC.The outcomes of LT for HCC are closely related with the assessment of transplantation candidates,management of patients on the waiting list and postoperative surveillance for HCC recurrence.PET imaging plays a significant role in LT process.The applications of PET imaging in LT for HCC are reviewed in this article.

Objective To investigate whether there are changes of the mast cells (MCs) and substance P ( SP) -ergic nerve terminals under light and electron microscopy, and to elucidate their possible roles in the pathogenesis of irritable bowel syndrome (IBS). Methods In 19 normal controls, 22 diarrhea predominant IBS ( D-IBS) and 20 constipation predominant IBS (C-IBS) , biopsies were taken from the terminal ileum, ileocecal junction, ascending colon and sigmoid colon. The MCs and the substance P (SP)-ergic nerve terminals, substance P receptor ( SPR) were stained by histochemical and immunohisto-chemical method respectively, and color image analyzer investigated the results qualitatively and quantitatively. The structure relation between the MCs and SP-ergic terminals was studied through an ultra-microscopy using in situs embedding technique and a light microscopic study in serial sections. Results The number of MCs in the terminal ileum, ileocecal junction, and ascending colon was significantly elevated in IBS (P

Objective: To evaluate the protective effect of Shenfu injection (SFI) against intestinal barrier dysfunction and second hit in rats with severe acute pancreatitis (SAP). Methods: Fifty-four male Wistar rats were randomly divided into sham operation group (n = 6), SAP group (n = 24), and SAP + SFI group (10 ml/kg body wt, n = 24). Sham operation group underwent laparotomy only. SAP model was established by retrograde injection of 5% sodium taurocholate into the bilipancreatic duct of Wistar rats. SAP+SFI group was given SFI (10 ml/kg) intaperitoneally 2 h before SAP establishment. Rats were sacrificed at 3,6,12 and 24 hours after operation. The samples of pancreas, lung and liver were collected for measuring the levels of myeloperoxidase (MPO) at 3,6,12, and 24 h after injection of sodium taurocholate. The pathological changes of the terminal ilea were observed under light microscopy, and the blood levels of diamine oxidase (DAO), tumor necrosis factor alpha (TNF-α) and interleukin-6(IL-6) were also measured at different time points. Results: The blood levels of TNF-α, IL-6 and DAO in SAP group were significantly higher than those in the sham operation group at all time points (P<0.01). The levels of intrapulmonary, intrapancreatic and intrahepatic MPO in SAP group were significantly than those in the sham operation group at 6,12, and 24 hours (P<0.01). The contents of DAO, TNF-α and IL-6 were significantly decreased in SAP + SFI group compared with in SAP group at all time points (P<0.05 or P<0.01). The contents of intrapulmonary, intrapancreatic and intrahepatic MPO were significantly decreased in SAP+SFI group compared with SAP group at 6,12, and 24 h after operation (P<0.05 or P<0.01). Intestinal pathological damages were obviously milder in SAP+SFI group than that in SAP group at 24 h after operation. Conclusion: SFI can protect the small intestine mucosal barrier and other organs from second hit by reducing the polymorphonuclear leucocyte detaining and inhibiting TNF-α and IL-6.