No abstract available.
Candida

No abstract available.
Nevus

No abstract available.
Onychomycosis

No abstract available.
Candida ; Onychomycosis

No abstract available.
Hair ; Humans ; Piedra ; Scalp ; Trichosporon

BACKGROUND: Few studies have compared the efficacy, cosmetic outcomes, and adverse events between 5-aminolevulinic acid photodynamic therapy (ALA-PDT) and methyl aminolevulinate-PDT (MAL-PDT) for actinic keratoses (AKs) in Asian ethnic populations with dark-skin. OBJECTIVE: We retrospectively compared the long-term efficacy, recurrence rates, cosmetic outcomes, and safety of ALA-PDT versus MAL-PDT for facial AKs in Koreans. METHODS: A total of 222 facial AKs in 58 patients were included in this study. A total of 153 lesions (29 patients) were treated with 5-ALA, and 69 lesions (29 patients) with MAL. ALA and MAL creams were applied for 6 hours and 3 hours, respectively; the lesions were then illuminated with a halogen lamp at 150 J/cm2 for ALA-PDT and a diode lamp at 37 J/cm2 for MAL-PDT. RESULTS: The complete response rates of ALA-PDT and MAL-PDT were 56.9% and 50.7%, respectively, with no significant difference at 12 months after treatment. No significant difference in recurrence rates was observed between the 2 PDT modalities at either 6 or 12 months after treatment. There was no significant difference in the cosmetic outcomes between the 2 treatment modalities at 12 months after PDT. However, ALA-PDT caused significantly more painful than MAL-PDT (p=0.005). The adverse events were mild to moderate, transient, and self-limiting for both modalities. CONCLUSION: MAL-PDT was similar to ALA-PDT in terms of long-term efficacy, recurrence rates, cosmetic outcomes, and adverse events; however, it was a significantly less painful procedure than ALA-PDT in our study.
Asian Continental Ancestry Group ; Follow-Up Studies* ; Humans ; Keratosis, Actinic* ; Photochemotherapy* ; Recurrence ; Retrospective Studies

Atypical junctional melanocytic hyperplasia is a rare condition with unknown etiology. It is characterized by focal atypical melanocytic proliferation limited in the basal layer. Although this lesion is difficult to separate from melanoma in situ (MIS), it could be distinguished from MIS by the lack of several features, including lateral spread, upward epidermal migration, marked cytologic atypia, finely granular "smoky" melanin pigment, mitotic figures, and a subjacent host inflammatory response. In one study, atypical junctional melanocytic hyperplasia was found in 6.2% (25/400) of otherwise normal intradermal nevi. However, to our knowledge, no case of atypical junctional melanocytic hyperplasia with intradermal nevus has ever been published in Korean dermatologic literatures. Herein, we report a rare and interesting case of atypical junctional melanocytic hyperplasia with intradermal nevus.
Hyperplasia ; Melanins ; Melanoma ; Nevus, Intradermal

The presence of various cutaneous disorders may reflect the occult internal malignancy. Bullous pemphigoid (BP), a common autoimmune skin disease, is characterized by the presence of subepidermal blisters. The association of bullous pemphigoid with internal malignant neoplasm has occasionally been reported. However, the relationship of bullous pemphigoid and malignancy is still controversial; the evidence for this association is increasing. Here, we report a rare case of a bullous pemphigoid associated with prostate adenocarcinoma.
Adenocarcinoma ; Blister ; Pemphigoid, Bullous ; Prostate ; Skin Diseases

Palisaded neutrophilic and granulomatous dermatitis (PNGD) is characterized histopathologically by the presence of granulomatous inflammation with or without leukocytoclastic vasculitis. It has been associated with multiple systemic diseases, particularly autoimmune conditions like rheumatoid arthritis and Behcet's disease. We report a 52-year-old woman with rheumatoid arthritis who presented with a single, non-tender, rapidly growing nodule on her right elbow. Histologic examination of the nodule revealed degenerated collagen, neutrophils, neutrophilic dust, fibrin, and mucin present in the centers of the palisades of histiocytes throughout the dermis. Herein, we report the abrupt onset of PNGD in a patient with rheumatoid arthritis.
Arthritis, Rheumatoid* ; Collagen ; Dermatitis* ; Dermis ; Dust ; Elbow ; Female ; Fibrin ; Histiocytes ; Humans ; Inflammation ; Middle Aged ; Mucins ; Neutrophils* ; Vasculitis

Erythema annulare centrifugum (EAC), first described by Darier in 1916, is characterized by annular, circinate, gyrate or serpiginous lesions. Although the pathogenesis of EAC is not fully understood, it is considered to be a hypersensitivity reaction to a wide variety of etiological factors, including autoimmune diseases, internal malignancies, drugs, infections, and pregnancy. To the best our knowledge, no case of EAC associated with Candida guilliermondii infection has ever been published in the Korean medical literature, and there have been a few reported cases associated with Candida albicans in other countries. Herein, we report on a rare and interesting case of EAC in a 62-year-old female patient with Candida guilliermondii infection.
Aminocaproic Acids ; Autoimmune Diseases ; Candida ; Candida albicans ; Erythema ; Female ; Humans ; Hypersensitivity ; Middle Aged ; Pregnancy