A case of thanatophoric dwarfism is presented. The previous gestation was polyhydramniotic and aborted spontaneously at 19th week. The aborted fetus showed marked micromelia. Present gestation was also polyhydramniotic and terminated by therapeutic abortion at 31th weeks due to skeletal deformity representing thanatophoric dwarfism. The fetus shows typical characteristics of thanatophoric dwarfism. Grossly the fetus shows marked micromelia, narrowed thorax with relatively normal length of trunk, and enlarged head. In the radiograph the femur shows characteristic ‘ telephone receiver’-like form. And the histological observations shows marked disturbances of the endochondral ossification.
Aborted Fetus ; Abortion, Therapeutic ; Congenital Abnormalities ; Female ; Femur ; Fetus ; Head ; Pregnancy ; Telephone ; Thanatophoric Dysplasia* ; Thorax

An epidemiological study is to observe and analyse 100 cases of lung cancer in Korean, which had been diagnosed actually at the general hospitals in Korea from 1970 through 1974, to discover the tendency of the lung cancer by sex, age, occupation, duration of clinical symptoms before diagnosis, site of cancer in lung, size of cancer, occurrence, treatment, prognosis, smoking and pathological findings as follows. 1. Males were affected 5.7 times more than females, the peak incidence of lung cancer were 50 years old age group. 2. The occupations of the cases were commerce, agriculture, industry, laborers and teachers, etc. in thht order. 3. The average duration symptoms from onset to diagnosis were 5.5 months. 4. The cancers were affected more right side than left side of the lungs, Particularly the most of them were affected in the upper lobes of the lungs. 5. The average diameter of the tumors was 5.5crX6.5cm, However the largest of them was 10cm X 13cm. 6. The most cases of the lung cancers were occurred primarily. 7. Out of the 100 cases, 58 cases had no treatment, 23 cases had palliative-symptomatic treatment, of cases by special chemo-therapy, 7 cases by surgery, and 5 cases by cobalt 60 or X-gay. 8. In the view point of prognosis, the most cases of the lung cancers died within one year atfer diagnosis. 9. The smoking was one of the causative factor of lung cancer, but there was no significant diferentiation by means of the amount of smoking. 10. The most cases of the lung cancers diangosed histo-pathologically, were epidermoid(squamous) type.
Agriculture ; Cobalt ; Commerce ; Diagnosis ; Epidemiologic Studies* ; Female ; Hospitals, General ; Humans ; Incidence ; Korea ; Lung Neoplasms* ; Lung* ; Male ; Middle Aged ; Occupations ; Prognosis ; Smoke ; Smoking

No abstract available.
Venous Thrombosis

In case of severe blepharoptosis, frontalis muscle suspension with fascia or frontalis transfer has been popular for decades, but these static procedures have some disadvantages such as lagophthalmos, lid lag and remnant ptosis. Twenty-six patients with severe blepharoptosis who underwent frontalis suspension, frontalis transfer, or levator resection at Yonsei University Severance Hospital from 1980 to 1988 were studied. The follow-up period of patients ranged from 10 to 18 years with a mean of 12 years. Surveys and clinical results were obtained, In our review of postoperative complications, lagophthalmos persisted in sleep and even in forced eye closure in most patients 2 to 6 months after operation. But no recurrence was noted. In conclusion, undercorrection of ptosis is more desirable than overcorrection. As well levator resection can be considered in selected cases to prevent complications.
Blepharoptosis* ; Fascia ; Follow-Up Studies* ; Humans ; Postoperative Complications ; Recurrence

Adenoid cystic carcinoma is known to be a neoplasm of the major and minor salivary glands but it also occurs in the lacrimal gland, external auditory canal, easphagus, breast and skin. Adenoid cystic carcinoma of salivary gland is a slow-growin nalignant tumor. Although metastasis of this tumor clevelnps in about half the cases, its meta taes to the overlying skin is not common, moreover the skin metastasis to the remote site is raely found. Primary cutaneous adenoid cystic carcinoma is rare and histologically indistingisl able from skin metastasis of adenoid cystic carcinoma of the salivary gland. A 53 year-old man presented a solitary, well defined, erythen at us, 1.3 x 1.3cm sized nodule on the vertex of the scalp, which revealed the typical histopatholog ndings of adenoid cystic carcinoma. One and half years ago, a tumor of the parotid gland va removed and proved to be a cribriform pattern of adenoid cystic carcinoma. The skin lesion was diaghosed as a skin metastasis of the alenoid cystic carcinoma of parotid gland rather than a primary cutaneous adenoid cystic carcinona because a similar pattern of adenoid cystic carcinorom had been discovered on the parotidg an l although it developed on the scalp, the usual site of primary cutaneous adenoid cystic carcinama.
Adenoids* ; Breast ; Carcinoma, Adenoid Cystic* ; Ear Canal ; Humans ; Lacrimal Apparatus ; Middle Aged ; Neoplasm Metastasis* ; Parotid Gland* ; Salivary Glands ; Salivary Glands, Minor ; Scalp ; Skin*

Intravascular papillary endotholial hyperplasia is a relatively rare (istose which is characterized by the development of endothelialdined papillary projections in a vascula humen. It is commonly found to be associated with thromboticrraterial and is now considered a reative process of the endothelium rather than a neoplastic one. Although this disease usually presents petri dish or bluish nodule on the head, neck or upper extremiti it can develop anywhere on the bod, . There are many reports about lesions in unusal locations, but t.hey are almost always solitary. A 61-year-old woman complained of multiple, tender, 1 x 1 to 4 x 5 creasized nodules on both hands, antecubital fossa, chest, abdomen, left shoulder and right calf. These the nodules showed reddish to bluish colors and had long hisbiries from 1 year to 7 years. Four our 13 lesions were excised for histopathologic diagnosis intravascular papillary endothelial hyperplaian 3 lesions and cavernous hemangioma in 1 lesion.(
Abdomen ; Diagnosis ; Endothelium ; Female ; Hand ; Head ; Hemangioma, Cavernous ; Humans ; Hyperplasia* ; Middle Aged ; Neck ; Shoulder ; Thorax

The incidence in women less than 35 years of age is increasing despite an overall decrease in newly diagnosed invasive cervieal cancer among all age groups. However the influence of young age on prognosis remains controversial. So 163 patients of invasive cervical cancer in women aged 35 or less treated from Jan. 1, 1984 to Dec. 31. 1993 at the Department of Obstetrics and Gynecology, Kosin Medical College, Pusan, Korea, were studied retrospectively. We obtained the following results; The 5-year survival rates by clinical stage were 88.7Y% in stage I b, 71.5% in stage IIa, 31.2% in stage IIb and O% in stage III or above. The lymph node metastasis rates by stage in RAH group, were 21.3% in stage I b and 31.8% in stage IIa. The lymph nodc metastasis rates by lesion size in RAH group, were 19.2% in 2cm below, 20.7% in 2-4cm and 40.0% in 4cm above. The 5-year survival rates in RAH group were 74,9% in lymph node positive group and 89.0% in lymph node negative group. The recurrenee rates by clinieal stage were 0% in stage Ia, 20.6% in stage I b, 22.2% in stage IIa, 50.0% in stage Ilb and 90.9% in stage III or above.
Busan ; Female ; Gynecology ; Humans ; Incidence ; Korea ; Lymph Nodes ; Neoplasm Metastasis ; Obstetrics ; Prognosis ; Retrospective Studies ; Survival Rate ; Uterine Cervical Neoplasms*

OBJECTIVE: The purpose of this study was to investigate clinical charactoristics of adenocarcinoma of the uterine cervix. STUDY METHODS: This study is a retrospective analysis of 103 patients with adenocarcinoma of cervix treated at the Kosin Medical center forom 1984 to 1993. RESULTS: The distribution by stage of disease included FIGO stage I, 51(49.6%); stage II, 32(31%); Stage III, 17(16.5%);Stage IV, 3(2.9%). The 2-year survival results for patients with stage I was 93.5%; stage II was 72.4%;stage III was 46.2% and stage IV was none survived. And 4 year survival results,'83.3/o, 591% and 33.3/o in stage I, II and III, reqxetively. The 4-year survivel rate varied significantly according to tumor size and lymph nade metastasis status-below 2cm 84.2%, 2cm~4cm 75%, above 4cm 0%: (stage I);negative node 91.3%, positive node 40% (stage I). The results of resurrent rate according to clinical stage was 11.8%, 25.8%, 84.6% and 100 % in stage I, ll, III and lV, respectively. CONCLUSION: Treatment strategies should be based on the stage of disease, tumor size, lymph node metastasis status and recurrent.
Adenocarcinoma* ; Cervix Uteri* ; Female ; Humans ; Lymph Nodes ; Neoplasm Metastasis ; Retrospective Studies

No abstract available.
Fournier Gangrene*

No abstract available.
Constriction, Pathologic* ; Sutures* ; Trachea*