Copper fragment was introduced into the vitreous body of fourteen albino rabbits through the scleral incision at equatorial region. Both photopic and scotopic ERGs were recorded for 30 days thereafter stimulated by the electronic photoflash of 2 msec duration.The changes in scotopic b-potential were roughly classified into 3 types. The first type (5 eyes) showed acute, severe reduction, extinguishing from 6 to 24 days. The second type (3 eyes) was characterized by the absence of any remarakble changes during the whole observation period, the final b'potential being 82,4% of the original value. In the third type (6 eyes), the b-potential decreased gradually and 24.3% of the pre' operative value was attained after 30 days. The latent time and the implicit time of the b-potential increased proportionally to the reduction of the b-wave. The scotopic a-wave behaved parallel to the b-wave, and in later stage, negative (-) type of ERGs were frequently encountered. The photopic a- and b-waves changed in the similar way as the scotopic a- and b-waves, respectively. The slitlamp biomicroscopy and ophthalmoscopy revealed the fibrous tissue proliferation around the copper fragment in relatively early stage. When the proliferation progressed and extended into the vitreous body, ERG showed reduction in b-potential, and sometimes increase in b-potential was noted In cases in which connective tissue encapsulated the copper and did not extend into the vitreous body, ERG changes were much milder and slower. In histological sesctions performed 2 weeks and 3 weeks after the insertion of copper fragment, the degeneration of the retina began both in the visual cell layer and ganglion cell layer almost simultaneously. When the ERG was extinguished, the retinal tissue showed complete destruction.
Connective Tissue ; Copper* ; Ganglion Cysts ; Ophthalmoscopy ; Rabbits ; Retina ; Retinaldehyde ; Vitreous Body

We have experienced a case of plexiform neurofibrorna of the right upper eyelid and orbit in a 12-year-old girl who had typical skin features of neurofibromatosis and no family history. The non-pulsating proptosis of the right eye and diffuse thickening with hypertrophy of the upper lid, had increased insiduciusly since the birth on. Biopsy taken from eyelirl lesion showed the features of plexiform neurofibroma. Skull X-ray and brain computerized tomogram showed that the right orbit was wider, with the enlarged mass and defects in orbital roof and lesser and greater wings of the sphenoid bone. The surgical excision of the right eyelid lesion was performed.
Biopsy ; Brain ; Child ; Exophthalmos ; Eyelids* ; Female ; Humans ; Hypertrophy ; Neurofibroma, Plexiform* ; Neurofibromatoses* ; Orbit* ; Parturition ; Skin ; Skull ; Sphenoid Bone

No abstract available.
Breast Implants* ; Breast* ; Contracture* ; Pregnancy*

No abstract available.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*

No abstract available.
Trichomonas*

No abstract available.
Trichomonas*

Thirty-nine patients with fixed drug eruption who visited the Department of Dermatology in National Medical Center from January 1g7g to December 1982 were selected. Among them, twentyseven patients performed skin biopsy and were evaluated histopathologically on the basis of duration. The results were as follows; ].In the early stage less than 1 week of duration, hydropic degeneration of basal cells, necrotic keratinocytes with eosinophilic cytoplasm and pknotic nucleus in the epidermis, and mixed cell infiltration with eosinophlis in the upper dermis were prominently. In the late stage more than 20 days of duration, acanthosis, an increased amount of melanin in the basal cell layer and presence of melanophages were found more prominent, however, hydropic degeneration of basal cells, papillary dermal ederna, inflammatory infiltration of mononuclear cells were found less prounced or absent.
Biopsy ; Cytoplasm ; Dermatology ; Dermis ; Drug Eruptions* ; Eosinophils ; Epidermis ; Humans ; Keratinocytes ; Melanins ; Skin

In glaucoma patients, optic nerve head analysis is very useful in early detection and progression during follow-up. Among optic nerve head analysis methods, the confocal laser tomographic scanner(Heidelberg Retina Tomograph: HRT) is actively studied for accurate and highly reproducible analysis.We analyzed the optic nerve head of 62 normal eyes(male 40 eyes, female 22 eyes) in third decade of Korean with HRT, and calculated the mean value of each parameters in HRT and evaluated the difference between men and women. We also studied the distribution fo the value of each parameter in normal third decade of Korean. In addition, for the parameters of Rim/Disc area ratio, we calculated the mean value in 6 divisions of optic nerve head.The mean value of Disc area was 2.039mm3, Cup area 0.593mm3, rim area 1.716mm3 and Cup/Disc area ratio 0.237. Rim volume, Maximal cup depth, Height variation contour, Mean retinal nerve fiber layer thickness, and Retinal nerve fiber layer cross sectional area were statistically different between men and women. For Rim/Disc area ratio, the maximal value was noted in nasal inferior(0.873) region, and the minimal value was in temporal(0.579) region. There was no statistically difference between men and women in Rim/Disc area ratio.
Female ; Follow-Up Studies ; Glaucoma ; Humans ; Male ; Nerve Fibers ; Optic Disk* ; Optic Nerve* ; Retina ; Retinaldehyde

The cytologic examination of the urine is very simple and inexpensive procedure for the detection and follow up the genitourinary tumors, and worthy as a mass screening test. The voided urines of 20 patients who were admitted to the department of urology, Seoul city hospital from October 1983 to September 1985 with the diagnosis of bladder carcinoma were analysed as to variations in PH and osmolality values and quality of cytologic smears. The same analyses were repeated after addition of trichloracetic acid (TCA) and after diuresis was obtained by Furosemide medication. Standardization of values of PH (average 2) and of osmolality (average 300 mosm/kg) was obtained by adding TCA to furosemide urine. The cellular smears of this TCA treated furosemide urine exhibited the finest cytological details when compared to the smears obtained by routine method.
Diagnosis* ; Diuresis ; Furosemide ; Hospitals, Urban ; Humans ; Hydrogen-Ion Concentration ; Mass Screening ; Osmolar Concentration ; Seoul ; Urinary Bladder ; Urology

Chondrodysplasia punctata is a rare congenital disorder of bone, occuring in infants, which is characterized by radiographic manifestation of premature deposition of punctate calcific densitiy in epiphyseal areas, preformed in cartilage. We experienced a case of rhizomelic type-chondrodysplsia punctata in a two day old female who showed short stature, symmetric shortening of proximal limbs, cataract, icthyositic skin lesion and characteristic coronal clefts in lumbar vertebral bodies on X-ray.
Cartilage ; Cataract ; Chondrodysplasia Punctata ; Chondrodysplasia Punctata, Rhizomelic* ; Congenital, Hereditary, and Neonatal Diseases and Abnormalities ; Extremities ; Female ; Humans ; Infant ; Skin