The ankle joint is a modified complex hinge joint which plays an important role in weight bearing, walking and standing. Injuries about the ankle joint cause destruction of not only bony architecture but often also the ligamentous and soft tissue component. So the goal of the treatment of ankle fracture is restoring normal relations of ankle mortise and regaining a smooth articular surface. The author have reviewed 84 cases of ankle fractures which were treated through the admission in the Orthopedic Department, In Je Medical College Pusan Paik Hospital from June 1979 to August 1986. The average duration of the follow-up was one year. The results obtained from this study were as follows : 1. The most common type was Danis-Weber type C. Nexts were B and A in order. According to the classification of Lauge-Hansen, the most common type was Pronation-external rotstion(39.2%). 2. In Danis-Weber type B and C, satisfactory result was obtained by operative treatment. 3. Danis-Weber's classification was very practical criteria for treatment of the ankle fracture.
Ankle Fractures ; Ankle Joint ; Ankle ; Busan ; Classification ; Clinical Study ; Follow-Up Studies ; Joints ; Ligaments ; Orthopedics ; Walking ; Weight-Bearing

Most obviuos will be the several anatomic differences between the proximal femur of the child and the adult. Fractures of the femoral neck in the children are extremely rsre and usually are the result of severe trauma in 80% of the cases. This accounts for the high frequency of serious associated injuries. In this injury the vascular anatomy changing with age, continuing growth potential and the effect of deforming forces play critical roles in high complication rate and these make treatment difficult. But still any secure guidelines for the treatment of this injury are not established and this is a field which requires more active research and further progress in future. 26 cases treated at Paik Hospital from Jan. 1979 to June 1988 were analyzed in clinical and radiological aspect and the following results were obtained. 1. The commonest type was Cervicotrochanteric fracture in 13 cases(50%),displaced one 21 cases. 2. In Transepiphyseal, Transcervical and Cervicotrochanteric fracture by early reduction and internal fixation, and in Intertrochanteric fracture by conservative treatment we gained satisfactory results. 3. We experienced 2 cases of coxa vara in nonthreaded pin used cases, 4 cases of premature epiphseal closure and 4 cases of avascular necrosis in threaded pin used ones. 4. Complications were developed in 13 cases (50%). These were 5 cases of coxa vara(19.2%) 4 cases of premature epiphyseal closure (15.4%) and 4 cases of avascul necrosis (15.4%). 5. Avascykar necrosis was developed in displaced fracture of Transcervical or Cervico- trochanteric fracture beyond postoperative 1 year. So. we recommend periodic long follow up for evaluation of avascular necrosis.
Adult ; Child ; Clinical Study ; Coxa Vara ; Femur ; Femur Neck ; Follow-Up Studies ; Hip ; Humans ; Necrosis

We report 22 patients with benign prostatic hyperplasia treated with transurethral balloon dilation and followed for six months thereafter. Of these 22 patients, 15 patients(68.2%) demonstrated significant improvement in modified Boyarsky symptom score and/or corrected peak flow rate on six months follow-up.
Follow-Up Studies ; Humans ; Prostatic Hyperplasia

No abstract available.
Carcinoma, Basal Cell ; Paget Disease, Extramammary

Gorham's syndrome is a rare disorder involing a proliferation of vascular channels associated with extensive loss of bony matrix. It starts in bone, but it may secondarily involve soft tissue and adjacent bones. Although the osteolysis usuakky arrests spontaneously, its biologic behavior is difficult to predict. The mechanism of steolysis is unkown, and the role of osteoclasts is controverwial We have experienced one case of Gorham's syndrome affecting the scapula and clavicle, which is reported in this paper with brief review of literature.
Clavicle ; Osteoclasts ; Osteolysis ; Scapula

No abstract available.
Arm

No abstract available.
Sperm Motility* ; Spermatozoa*

BACKGROUND: In patients with systemic lupus erythematosus (SLE), serum factors play a role in the apoptosis and necrosis of neutrophils. We intended to verify that autoantibodies including anti-dsDNA antibody are one of the factors. We also investigated the potential usefulness of simultaneous flow cytometric measurement of cytotoxicity and autoantibody binding to neutrophils in SLE sera for evaluation of disease activity. METHODS: A total of 228 sera from 48 patients with lupus nephritis (LN), 19 patients with SLE without LN, 35 patients with rheumatoid arthritis (RA) and 40 healthy males were studied. Whole blood from healthy males mixed with test sera was incubated. Autoantibody binding, apoptosis and necrosis of neutrophils were measured by flow cytometry using IgG-FITC and 7-aminoactinomycin D after a 20-hour incubation period or after adjustments of incubation conditions. The results were expressed as the test/healthy control ratio of measured values, and the correlations between these results and anti-dsDNA antibody levels were investigated. RESULTS: IgG mean fluorescence intensity (MFI) ratio was 1.0+/-0.3, 1.6+/-1.6, 2.0+/-1.5 and 4.8+/-7.5 in the healthy, RA, SLE and LN group, respectively, and showed a significant increase in the LN group when compared with the healthy group (N=20 in each group, P<0.05). Apoptosis & necrosis ratio was 1.0+/-0.2, 1.0+/-0.5, 1.6+/-1.0 and 2.6+/-1.9 in each of the above 4 groups, and showed a significant increase in the LN group when compared with the healthy (P<0.005) and RA group (P< 0.01). By immunofluorescence microscopy, increased nuclear reactivities on neutrophils by autoantibody binding were observed in 12 (60%) of 20 LN sera. All three correlations between anti-dsDNA antibody level, apoptosis & necrosis ratio and IgG MFI ratio were significant (P<0.0005). Preincubation with DNA extracts decreased both IgG MFI ratio and apoptosis & necrosis ratio significantly (N=25, P<0.05). CONCLUSIONS: Our findings confirm the previous reports of increased neutrophil apoptosis in the peripheral blood of patients with SLE. This study indicates that anti-dsDNA antibody or other antinuclear antibodies in sera are associated with an active increase in the apoptosis and necrosis of neutrophils as well as simple binding to neutrophils. This may suggest that autoantibodies increase the exposure of autoantigen DNA and exacerbate autoimmunity in the pathogenesis. Although further studies are needed, we suggest that measuring the cytotoxicity and autoantibody binding to neutrophils in SLE serum simultaneously by flow cytometry should be a useful test for evaluation of disease activity.
Antibodies, Antinuclear ; Apoptosis* ; Arthritis, Rheumatoid ; Autoantibodies ; Autoimmunity ; DNA ; Flow Cytometry ; Fluorescence ; Humans ; Immunoglobulin G ; Lupus Erythematosus, Systemic* ; Lupus Nephritis ; Male ; Microscopy, Fluorescence ; Necrosis ; Neutrophils*

PURPOSE: Recent randomized prospective data suggest that early hyperglycemia is associated with high mortality in critically ill patients and that tight glucose control leads to an improved outcome. This concept has not been carefully examined in trauma patients. The purpose of this study was to determine the relationship of different levels of early hyperglycemia to the clinical outcomes in trauma patients. METHODS: A retrospective study of 309 cases of trauma victims who visited the Emergency Department of Daegu Catholic University Hospital from March 2003 to February 2004 was made. Patients younger than 15 years of age and patients having diabetes mellitus were excluded. The records of all of these patients were reviewed for age, the Injury Severity Score (ISS), Glasgow Coma Scale (GCS) score, blood glucose, lengths of ICU and hospital stays, infection morbidity, and mortality. They were divided into three groups by their glucose level (> or = 110 mg/dl and < 110 mg/dl, > or = 140 mg/dl and < 140 mg/dl, > or = 200 mg/dl and < 200 mg/dl). Each group was subdivided into hyperglycemic and non-hyperglycemic subgroups. RESULTS: Hyperglycemia was associated with increased infection morbidity, and mortality. Patients with hyperglycemia (> or = 110 mg/dl, > or = 140 mg/dl, > or = 200 mg/dl) showed higher mortality compared to the corresponding non-hyperglycemic groups (< 110 mg/dl, < 140 mg/dl, < 200 mg/dl) [(0.7% vs 13.0%, 0.5% vs 22.7%, 2.6% vs 45.7%, respectively (p<0.001)]. A univariate logistic regression analysis revealed a significant relationship of age, ISS, GCS score, and blood glucose (> or = 110 mg/dl, > or =140 mg/dl, > or = 200 mg/dl) with mortality. A multivariate logistic regression analysis addressing the effects of age, ISS, and GCS score showed a significant relationship among age (p<0.001), ISS (p<0.001), glucose > or = 140 mg/dl (0.042), and death. In the univariate logistic regression analysis of these variables to infection, we observed a significant correlation between all examined variables and infection, except for glucose > or = 110 mg/dl. Glucose > or = 200 mg/dl (p= 0.007), age (p=0.014), and ISS (p<0.001) were independent predictors of infection in the multivariate logistic regression analysis. CONCLUSION: Early hyperglycemia was associated with higher injury severity, infection rate, and mortality rate. Early hyperglycemia defined as glucose > or = 200 mg/dl was an independent predictor of increased infection rate in trauma patients. Also, early hyperglycemia defined as glucose > or = 140 mg/dl showed a significant independent relationship to death.
Blood Glucose ; Critical Illness ; Daegu ; Diabetes Mellitus ; Emergency Service, Hospital ; Glasgow Coma Scale ; Glucose ; Humans ; Hyperglycemia* ; Injury Severity Score ; Length of Stay ; Logistic Models ; Mortality ; Prognosis* ; Retrospective Studies

No abstract available.
Peritoneal Dialysis, Continuous Ambulatory* ; Pharmacokinetics* ; Renal Dialysis*