Purpose: There are a variety of techniques for treating chronic prostatitis. Regardless of the presence of infections, antibiotics were arbitrarily prescribed for 4-12 weeks, but there seemed to be ongoing debate of their effectiveness and side effects. Uro-vaxom(R) is known as an effective treatment for urinary tract infection due to its initiation the urothelial immune system activity. This study was performed to investigate for the possibility of Uro-vaxom(R) as a drug for use in non-inflammatory chronic prostatitis. Materials and Methods: 95 patients, diagnosed as chronic pelvic pain syndrome (CPPS) (National Institutes of Health (NIH)-category IIIB), were divided into three groups: group A, 35 patients were given levofloxacin 100mg TID and Uro-vaxom(R) 60mg OD for the first 4 weeks, followed by only Uro-vaxom(R) 60mg OD for the next 8 weeks; group B, 30 patients were given only Uro-vaxom(R) 60mg OD before breakfast for 12 weeks; group C, the patients were treated with levofloxacin 100mg TID for 4 weeks. All the patients were reevaluated 4 weeks and 12 weeks later. Results: The initial diagnostic stati, the NIH-Chronic Prostatitis Symptom Index (CPSI) were 25.1+/-2.7, 24.4+/-3.2 and 24.7+/-2.2 for groups A, B and C, respectively. In groups A and B, the NIH-CPSI after 12 weeks were 13.5 2.3 and 13.9+/-2.7, respectively, and showed noticeable improvements (p<0.05). In group C, the NIH-CPSI was 15.7+/-3.4, which was less improved compared to groups A and B (p>0.05). No patients experienced any adverse symptoms due to Uro-vaxom(R) intake. Conclusions: Uro-vaxom(R) could be appointed as an alternative method for the treatment of chronic prostatitis.
Academies and Institutes ; Anti-Bacterial Agents ; Breakfast ; Humans ; Immune System ; Levofloxacin ; Pelvic Pain* ; Prostatitis ; Urinary Tract Infections ; Urinary Tract*

PURPOSE: To describe the characteristic MR imaging findings of dysembryoplastic neuroepithelial tumor(DNT). MATERIALS & METHODS: We retrospectively reviewed MR images and pathologic findings of seven patients(five maleand two female, mean age 22) with surgically proven DNTs. We analyzed the location, size, configuration, signal intensity and contrast enhancement of nodules and accompanying calcifications, surrounding edema and calvarialchanges. RESULTS: All tumors were located in the cortical and subcortical portions of the temporal lobes. Most tumors showed small well-demarcated gyriform cystic nodules with almost the same signal intensity as that of the cerebrospinal fluid. Nodule margins were more sharply delineated on T2 than on T1-weighted images because on the former the peripheral portion of nodules shows high signal intensity. None of the patients showed surrounding edema or mass effect. On contrast-enhanced study, one of five patients showed subtle peripheral enhancement. Two patients showed included dense calcified nodules adjacent to cystic nodules, and two showed overlying calvarial thinning. CONCLUSION: Multiple small gyriform intracortical cystic nodules and occasional dense nodular calcifications are the characteristic findings of DNTs, and these may be differentiated from other focal lesion sin patients with temporal lobe epilepsy with the help of MR imaging.
Edema ; Epilepsy, Temporal Lobe ; Female ; Humans ; Magnetic Resonance Imaging* ; Neoplasms, Neuroepithelial* ; Retrospective Studies ; Temporal Lobe

Chronic spontaneous urticaria (CSU) is defined as the occurrence of spontaneous wheals, angioedema, or both for >6 weeks in the absence of specific causes. It is a common condition associated with substantial disease burden both for affected individuals and societies in many countries, including Korea. CSU frequently persists for several years and requires high-intensity treatment; therefore, patients experience deteriorations in quality of life and medication-associated complications. During the last decade, there have been major advances in the pharmacological treatment of CSU and there is an outstanding need for evidence-based guidelines that reflect clinical practice in Korea. The guidelines reported here represent a joint initiative of the Korean Academy of Asthma, Allergy and Clinical Immunology and the Korean Dermatological Association, and aim to provide evidence-based guidance for the management of CSU in Korean adults and children. In Part 1, disease definition, guideline scope and development methodology as well as evidence-based recommendations on the use of antihistamines and corticosteroids are summarized.

Chronic spontaneous urticaria (CSU) is defined as the occurrence of spontaneous wheals, angioedema, or both for >6 weeks in the absence of specific causes. It is a common condition associated with substantial disease burden both for affected individuals and societies in many countries, including Korea. CSU frequently persists for several years and requires high-intensity treatment; therefore, patients experience deteriorations in quality of life and medication-associated complications. During the last decade, there have been major advances in the pharmacological treatment of CSU and there is an outstanding need for evidence-based guidelines that reflect clinical practice in Korea. The guidelines reported here represent a joint initiative of the Korean Academy of Asthma, Allergy and Clinical Immunology and the Korean Dermatological Association, and aim to provide evidence-based guidance for the management of CSU in Korean adults and children. In Part 1, disease definition, guideline scope and development methodology as well as evidence-based recommendations on the use of antihistamines and corticosteroids are summarized.