No abstract available.
Humans ; Siblings*

No abstract available.
Child* ; Humans ; Infant* ; Ultrasonography

No abstract available.
Child* ; Humans ; Infant* ; Ultrasonography

PURPOSE: Biochemical confirmation of congenital hypothyroidism takes about 10 days, which may result in a delay in diagnosis. The delay could be reduced if a faster method of investigation such as knee radiograph is used. The aim of this study is to assess the value of plain radiography of the knee in providing supportive evidence for the diagnosis of congenital hypothyroidism. METHODS: Neonates with a screening TSH over 20microunit/mL or free T4 under 0.85ng/dL were referred for further investigation during period of 1992-1998. We included 116 patients whose results were all available. Diagnosis was confirmed by measuring serum TSH, T4, free T4 by radioimmunoassay, radioisotope scan and ultrasonography of the thyroid. Radiography of the knee was obtained and ossification center sizes were measured. RESULTS: Among 116 neonates, 31 were normal and congenital hypothyroisism was confirmed in 85 neonates. There was a statistically significant difference between the controls and the patients in regards to both biochemical data and knee epiphyseal ossification center size. In the congenital hypothyroidism group, there were a significant difference in biochemical data and knee epiphyseal ossification center size according to the diagnosis, and significant correlation between biochemical data and knee ossification center size, especially with serum T4 and combined mean epiphyseal diameter(r=0.56, P<0.01). In the patient group, simple regression equation was made between biochemical data and knee ossification center size. Combined mean epiphyseal diameter(mm) was 0.544 T4+4.161, combined epiphyseal surface area(mm2) was 2.940 T4+14.283. If T4 is below 7 microgram/dL, combined mean epiphyseal diameter is below 8mm and surface area is below 34mm2. CONCLUSION: In neonates with abnormal thyroid screening, knee radiograph showing a combined mean epiphyseal diameter of 8mm or less and surface area of 34mm2 or less suggests congenital hypothyroidism prior to biochemical confirmation, requiring thyroxine treatment.
Congenital Hypothyroidism* ; Diagnosis ; Epiphyses* ; Humans ; Infant, Newborn* ; Knee* ; Mass Screening ; Radiography ; Radioimmunoassay ; Thyroid Function Tests* ; Thyroid Gland* ; Thyroxine ; Ultrasonography

No abstract available.
Appendicitis* ; Child* ; Humans

Cerebrovascular accident (CVA) is the most common cause of neurologic disorder accompanying grave prognosisand its mortality above 50%. Prior to introduction of the CT, the diagnosis have been depended on clinicalfindings and spinal puncture. Radiologic diagnostic methods, such as angiography, ventriculography andradioisotope scanning are invasive and less sentitive in diagnosis of CVA than CT. The size, location andextension of the intracranial pathology and ventricular penetration are accureately and rapidly portrayed by CT.Consequently, CT plays impotant role in effective tratement and evaluation of prognosis in CVA. Authors analyzed63 cases of diagnosed CVA who were performed CT scan in Korea General Hospital from November 1981 to April 1982.The results were as follows. 1. The most prevalent age group of CVA was 6th decade, and then 7th and 5th decadesin decreasing order. The sex ration between male and female was 1.2:1. 2. The causes of CVA were hypertensivehemorrhage (50.8%), vascular occlusive disease(22.2%), anurysm ruture (4.8%), arteriovenous malformation (3.2%)and hemorrhage of unknown etiology (19.0%). 3. The most common site of hemorrhage was basal ganglia (34.6%) andthen thalamus(21.8%) and cerebral lobes(20.5%). In infarction, the common sites were the lobes(64.7%) and thebasal ganglia (35.3%) 4. Round or oval shaped hematomas of high density (85.9%) were frequent findings ofhemorrhage and mass effect occured in 75.6%. 5. All infarctions were low in density ; Most of the lesion wasinhomogeneous(70.6%) and the rests were homogeneous. Mass effects were seen in 29.4%.
Angiography ; Arteriovenous Malformations ; Basal Ganglia ; Diagnosis ; Female ; Ganglia ; Hematoma ; Hemorrhage ; Hospitals, General ; Humans ; Infarction ; Korea ; Male ; Mortality ; Nervous System Diseases ; Pathology ; Prognosis ; Spinal Puncture ; Stroke ; Tomography, X-Ray Computed

The primary objective of this study was to make the prediction percentile tabulation of the sum of mesiodistal widths of the unerupted permanent canines and premolars derived from the sum of mesiodistal widths of the erupted permanent incisors in normal and crowding groups. Crowding group consisted of 85 pairs of dental casts (42 males and 43 females) with more than 4mm of crowding in anteriors. Normal group consisted of 109 pairs of dental casts (65 males and 44 females) with less than 1mm of spacing or crowding in anteriors. The mesiodistal crown diameters of permanent teeth were measured from the dental casts using the sliding calipers (Mitutoyo Co., Japan). From the study, the obtained results were as follows: There were not significant differences between male and female in both groups on the basis of the ratios between the sum of mesiodistal widths of incisors and the sum of mesiodistal widths of canines and premolars. There was not significant difference between two groups on the basis of the ratio between the sum of mesiodistal widths of mandibular incisors and the sum of mesiodistal widths of mandibular canines and premolars and was significant differences between two groups on the basis of the ratio between the sum of mesiodistal widths of mandibular incisors and the sum of mesiodistal widths of maxillary canines and premolars. There was significant difference between two groups on the basis of the ratio between the sum of mesiodistal widths of maxillary incisors and the sum of mesiodistal widths of mandibular canines and premolars. There was significant difference between two groups on the basis of the ratio between the sum of mesiodistal widths of maxillary incisors and the sum of mesiodistal widths of maxillary canines and premolars. The percentile prediction tabulations were made in an attempt to predict the sum of mesiodistal widths of the unerupted permanent canines and premolars derived from the sum of mesiodistal widths of the erupted permanent mandibular incisors in each group. The percentile prediction tabulations were made in an attempt to predict the sum of mesiodistal widths of the unerupted permanent canines and premolars derived from the sum of mesiodistal widths of the erupted permanent maxillary incisors in each group.
Bicuspid* ; Crowding ; Crowns ; Female ; Humans ; Incisor ; Male ; Tooth

No abstract available.
Child* ; Humans ; Seizures*

BACKGROUND: Recently, Doppler echocardiography has been widely used to evaluate left ventricular(LV) diastolic filling. However, There are only limited date about the influence of LV systolic function on the pattern of left ventricular diastolic filling. METHODS: To evaluate the changes of Doppler echocardiographic parameters of left ventricular filling induced by variations in left ventricular systolic function in dilated cardiomyopathy(DC) with heart failure(HF), 25 patients(M : F=14 : 11) with DC and HF, and 21 age-matched normal subjects(M : F=13 : 8) were examined by ECG, phonocardiography and echocardiography. From the Doppler recording, A2D(time from second heart sound to the onset of early diastolic mitral flow), peak velocity at early diastole(E) and late diastole(A), ratio of E to A velocity(E/A) and flow velocity integral(FVI) were measured. RESULTS: In 22 patients with DC and HF without mitral regurgitation(MR), A2D was significantly prolonged(119.5+/-12.7 vs 92.4+/-14.1msec, p<0.01), and early diastolic peak velocity and E/A velocity ratio were decreased as compared with the normal subjects(E=0.39+/-0.08 vs 0.57+/-0.12m/sec, p<0.01, E/A : 0.87+/-0.19 vs 1.33+/-0.19 vs 1.33+/-0.18, p<0.05). There were significant correlations between A2D and FVI(r=+0.73, p<0.01), and between E/A velocity ratio and FVI(r=-0.78, p<0.01). However, in 3 patients with MR, A2D(88.7+/-12.1msec), E(0.56+/-0.05m/sec), and E/A(1.32+/-0.12) were similar to those in normal subjects, despite of decreased FVI(12.0+/-0.9cm). CONCLUSIONS: These data show that a change of left ventricular systolic function in patients without MR may influence a diastolic filling pattern of left ventricle but not in patient with MR, and suggest that MR masks left ventricular distolic filling abnormalities.
Cardiomyopathy, Dilated* ; Echocardiography ; Echocardiography, Doppler* ; Electrocardiography ; Heart ; Heart Sounds ; Heart Ventricles ; Humans ; Masks ; Phonocardiography ; Ventricular Function, Left*

No abstract available.
Pericardial Effusion*